TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 442.51 | Formula: C26H26N4O3
H donors: 1 H acceptors: 3 LogP: 3.85 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCCCNC(=O)C1C(=Nc2c(N1C(=O)c1ccncc1)cccc2)c1ccc(cc1)OC
InChi: 1S/C26H26N4O3/c1-3-4-15-28-25(31)24-23(18-9-11-20(33-2)12-10-18)29-21-7-5-6-8-22(21)30(24)26(32)19-13-16-27-17-14-19/h5-14,16-17,24H,3-4,15H2,1-2H3,(H,28,31)
InChiKey: XYMXLEXUPCOQHZ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	tyrosine protein kinase shark	0.019	0.2726	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase Src64B	0.019	0.2726	1
Brugia malayi	ephrin receptor 1 precursor	0.0075	0.0773	0.1108
Schistosoma mansoni	serine/threonine RGC	0.0075	0.0773	0.2837
Echinococcus granulosus	insulin receptor	0.0075	0.0773	0.2837
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0075	0.0773	0.2837
Leishmania major	protein kinase, putative	0.0075	0.0773	0.5
Toxoplasma gondii	protein kinase domain-containing protein	0.0075	0.0773	1
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0115	0.1462	0.2095
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0063	0.0581	0.2133
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Loa Loa (eye worm)	jmjC domain-containing protein	0.006	0.0522	0.0748
Brugia malayi	protein-tyrosine kinase	0.019	0.2726	0.3905
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine protein kinase Srms	0.019	0.2726	1
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Trypanosoma cruzi	protein kinase, putative	0.0075	0.0773	0.5
Echinococcus granulosus	expressed conserved protein	0.0115	0.1462	0.5365
Schistosoma mansoni	hypothetical protein	0.0115	0.1462	0.5365
Onchocerca volvulus		0.0115	0.1462	0.1825
Echinococcus granulosus	histone lysine methyltransferase setb	0.0063	0.0581	0.2133
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Entamoeba histolytica	protein kinase, putative	0.0075	0.0773	0.000000048638
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0075	0.0773	0.1108
Schistosoma mansoni	tensin	0.0115	0.1462	0.5365
Trichomonas vaginalis	set domain proteins, putative	0.0502	0.8012	0.7845
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0302	0.4634	0.5
Brugia malayi	Protein kinase domain containing protein	0.019	0.2726	0.3905
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0075	0.0773	0.2837
Loa Loa (eye worm)	SH2 domain-containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	SHC transforming protein 3	0.0115	0.1462	0.5365
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.0302	0.4634	0.5
Loa Loa (eye worm)	hypothetical protein	0.019	0.2726	0.3905
Brugia malayi	Tyrosine-protein kinase PR2	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.019	0.2726	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Onchocerca volvulus		0.0075	0.0773	0.0965
Loa Loa (eye worm)	TK/ACK protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/DDR protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0075	0.0773	0.2837
Echinococcus multilocularis	lysine specific demethylase 5A	0.0035	0.0103	0.0378
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FAK protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Brugia malayi	Tyrosine-protein kinase abl-1	0.019	0.2726	0.3905
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Echinococcus granulosus	epidermal growth factor receptor	0.0075	0.0773	0.2837
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0095	0.1115	0.4091
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0115	0.1462	0.5365
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0115	0.1462	0.5365
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0115	0.1462	0.5365
Echinococcus multilocularis	NCK adaptor protein	0.0115	0.1462	0.5365
Loa Loa (eye worm)	TK/ABL protein kinase	0.019	0.2726	0.3905
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/ALK protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase shark	0.019	0.2726	1
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0063	0.0581	0.7519
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0061	0.0542	0.1988
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0619	1	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Schistosoma mansoni	protein tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.019	0.2726	1
Onchocerca volvulus		0.0115	0.1462	0.1825
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Echinococcus granulosus	kinase suppressor of Ras 1	0.0075	0.0773	0.2837
Trichomonas vaginalis	TKL family protein kinase	0.0075	0.0773	0.000000048638
Schistosoma mansoni	hypothetical protein	0.0115	0.1462	0.5365
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	jmjC domain containing protein	0.0035	0.0103	0.0148
Loa Loa (eye worm)	TK/CSK protein kinase	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	hypothetical protein	0.005	0.035	0.0502
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0075	0.0773	0.5
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase Blk	0.019	0.2726	1
Echinococcus multilocularis	SH2 motif	0.0115	0.1462	0.5365
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0035	0.0103	0.0378
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0115	0.1462	0.2095
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Schistosoma mansoni	tyrosine protein kinase	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.019	0.2726	0.3905
Brugia malayi	Tensin	0.0115	0.1462	0.2095
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0075	0.0773	0.2837
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	jmjC domain-containing protein	0.0035	0.0103	0.0148
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Entamoeba histolytica	protein kinase, putative	0.0075	0.0773	0.000000048638
Echinococcus multilocularis	tyrosine protein kinase Abl	0.019	0.2726	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0302	0.4634	0.5
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0773	0.5
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.019	0.2726	1
Echinococcus multilocularis	c src tyrosine kinase	0.019	0.2726	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Schistosoma mansoni	growth factor receptor-bound protein	0.0115	0.1462	0.5365
Loa Loa (eye worm)	TK/RYK protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.1462	0.2095
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Toxoplasma gondii	STE kinase	0.0075	0.0773	1
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK/EPH protein kinase	0.0075	0.0773	0.1108
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0115	0.1462	0.5365
Echinococcus multilocularis	epidermal growth factor receptor	0.0075	0.0773	0.2837
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Loa Loa (eye worm)	TK/Met protein kinase	0.0075	0.0773	0.1108
Brugia malayi	STAT protein, DNA binding domain containing protein	0.0115	0.1462	0.2095
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Echinococcus granulosus	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Schistosoma mansoni	tensin-related	0.0115	0.1462	0.5365
Leishmania major	hypothetical protein, conserved	0.0075	0.0773	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase ABL1	0.019	0.2726	1
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Brugia malayi	cytokine inducible SH2-containing protein 5	0.0115	0.1462	0.2095
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Onchocerca volvulus		0.019	0.2726	0.3402
Plasmodium falciparum	tyrosine kinase-like protein	0.0075	0.0773	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	tensin	0.0115	0.1462	0.5365
Echinococcus granulosus	tyrosine protein kinase HCK	0.0075	0.0773	0.2837
Schistosoma mansoni	suppressor of cytokine signaling	0.0115	0.1462	0.5365
Onchocerca volvulus		0.019	0.2726	0.3402
Loa Loa (eye worm)	SRC-1	0.019	0.2726	0.3905
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.019	0.2726	0.2116
Echinococcus multilocularis	protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	jmjC domain containing protein	0.0095	0.1115	0.1598
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0075	0.0773	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0115	0.1462	0.5365
Schistosoma mansoni	jumonji domain containing protein	0.0075	0.0785	0.2881
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.019	0.2726	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Trypanosoma brucei	protein kinase, putative	0.0075	0.0773	0.5
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0115	0.1462	0.5365
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Schistosoma mansoni	tensin	0.0115	0.1462	0.5365
Brugia malayi	hypothetical protein	0.019	0.2726	0.3905
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0115	0.1462	0.5365
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0441	0.698	1
Giardia lamblia	Kinase	0.0075	0.0773	0.0773
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Onchocerca volvulus		0.019	0.2726	0.3402
Schistosoma mansoni	SH2A	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	ephrin receptor	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.019	0.2726	0.3905
Echinococcus multilocularis	tensin	0.0115	0.1462	0.5365
Echinococcus granulosus	NCK adaptor protein	0.0115	0.1462	0.5365
Giardia lamblia	Kinase, NEK	0.0075	0.0773	0.0773
Echinococcus granulosus	integrin linked protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	SH2 domain-containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	tyrosine protein kinase pr2	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase Srms	0.019	0.2726	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK/ROR protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK protein kinase	0.019	0.2726	0.3905
Brugia malayi	hypothetical protein	0.0075	0.0773	0.1108
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0115	0.1462	0.1825
Echinococcus granulosus	c src tyrosine kinase	0.019	0.2726	1
Echinococcus granulosus	SH2 domain containing protein 7	0.0115	0.1462	0.5365
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0075	0.0773	0.2837
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0075	0.0773	0.1108
Schistosoma mansoni	ephrin receptor	0.0075	0.0773	0.2837
Echinococcus multilocularis	protein kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0115	0.1462	0.5365
Echinococcus granulosus	ephrin type A receptor 4 A	0.0075	0.0773	0.2837
Brugia malayi	SH2 domain containing protein	0.019	0.2726	0.3905
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	transfer RNA-Thr	0.0075	0.0773	0.2837
Brugia malayi	hypothetical protein	0.0099	0.1191	0.1707
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine protein kinase Fyn	0.019	0.2726	1
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.019	0.2726	1
Plasmodium falciparum	protein kinase, putative	0.0075	0.0773	1
Onchocerca volvulus		0.0075	0.0773	0.0965
Loa Loa (eye worm)	SH2 domain-containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	tyrosine protein kinase Fyn	0.019	0.2726	1
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	protein kinase	0.0075	0.0773	0.2837
Onchocerca volvulus		0.0063	0.0581	0.0726
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0075	0.0773	0.1108
Entamoeba histolytica	protein kinase, putative	0.0115	0.1462	0.0747
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Brugia malayi	Guanylyl cyclase protein 23	0.0075	0.0773	0.1108
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0075	0.0773	0.2837
Brugia malayi	RhoGAP domain containing protein	0.0115	0.1462	0.2095
Schistosoma mansoni	vav2	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Echinococcus multilocularis	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0099	0.1191	0.1707
Echinococcus granulosus	tyrosine protein kinase Src42A	0.019	0.2726	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Echinococcus multilocularis	signal transduction protein lnk realted	0.0115	0.1462	0.5365
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0115	0.1462	0.1825
Plasmodium falciparum	protein kinase, putative	0.0075	0.0773	1
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0115	0.1462	0.0747
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0075	0.0773	1
Onchocerca volvulus		0.019	0.2726	0.3402
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0075	0.0773	0.2837
Brugia malayi	tRNA modification GTPase TrmE family protein	0.0115	0.1462	0.2095
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0075	0.0773	0.2837
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.019	0.2726	0.3905
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0115	0.1462	0.5365
Echinococcus granulosus	activated cdc42 kinase 1	0.0075	0.0773	0.2837
Brugia malayi	Pre-SET motif family protein	0.0441	0.698	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0115	0.1462	0.2095
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	serine/threonine protein kinase	0.0075	0.0773	0.2837
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0075	0.0773	0.0965
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0115	0.1462	0.5365
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	insulin receptor	0.0075	0.0773	0.2837
Schistosoma mansoni	adapter molecule crk	0.0115	0.1462	0.5365
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus granulosus	protein tyrosine kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0115	0.1462	0.2095
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	activin receptor type	0.0075	0.0773	0.2837
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0115	0.1462	0.5365
Echinococcus granulosus	activin receptor type	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Onchocerca volvulus		0.0075	0.0773	0.0965
Loa Loa (eye worm)	hypothetical protein	0.0099	0.1191	0.1707
Leishmania major	protein kinase, putative	0.0075	0.0773	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Brugia malayi	Pre-SET motif family protein	0.0063	0.0581	0.0833
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0115	0.1462	0.5365
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.019	0.2726	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Schistosoma mansoni	serine/threonine protein kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine kinase	0.019	0.2726	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine protein kinase Fyn	0.019	0.2726	1
Schistosoma mansoni	eyes absent homolog	0.0099	0.1191	0.4371
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Entamoeba histolytica	SH2 domain containing protein	0.0115	0.1462	0.0747
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus granulosus	receptor type guanylyl cyclase	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine kinase	0.019	0.2726	1
Schistosoma mansoni	tensin	0.0115	0.1462	0.5365
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.019	0.2726	1
Onchocerca volvulus		0.0115	0.1462	0.1825
Onchocerca volvulus		0.0115	0.1462	0.1825
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0115	0.1462	0.5365
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0075	0.0773	0.2837
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	signal transduction protein lnk-related	0.0115	0.1462	0.5365
Echinococcus multilocularis	activated cdc42 kinase 1	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0115	0.1462	0.5365
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0773	0.5
Echinococcus granulosus	raf serine:threonine protein kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.019	0.2726	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0063	0.0581	0.2133
Echinococcus granulosus	natriuretic peptide receptor 1	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.019	0.2726	1
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0075	0.0773	0.2837
Onchocerca volvulus		0.0075	0.0773	0.0965
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Loa Loa (eye worm)	serine/threonine protein kinase	0.0075	0.0773	0.1108
Onchocerca volvulus		0.019	0.2726	0.3402
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Schistosoma mansoni	shc transforming protein	0.0115	0.1462	0.5365
Brugia malayi	C-terminal src kinase protein 1	0.0075	0.0773	0.1108
Echinococcus multilocularis	epidermal growth factor receptor	0.0075	0.0773	0.2837
Echinococcus multilocularis	N chimaerin	0.0115	0.1462	0.5365
Entamoeba histolytica	ankyrin repeat protein	0.0075	0.0773	0.000000048638
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0581	0.0833
Toxoplasma gondii	protein kinase	0.0075	0.0773	1
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0115	0.1462	0.5365
Echinococcus granulosus	SH2 motif	0.0115	0.1462	0.5365
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0619	1	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine protein kinase Lyn	0.019	0.2726	1
Echinococcus multilocularis	SHC transforming protein 3	0.0115	0.1462	0.5365
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0075	0.0773	1
Echinococcus granulosus	N chimaerin	0.0115	0.1462	0.5365
Onchocerca volvulus		0.0075	0.0773	0.0965
Onchocerca volvulus		0.0075	0.0773	0.0965
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.019	0.2726	0.3905
Echinococcus multilocularis	heat shock protein 70	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase Blk	0.019	0.2726	1
Echinococcus granulosus	tyrosine kinase	0.0075	0.0773	0.2837
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0075	0.0773	0.1108
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0115	0.1462	0.5365
Onchocerca volvulus		0.0502	0.8012	1
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0075	0.0773	0.2837
Trichomonas vaginalis	TKL family protein kinase	0.0075	0.0773	0.000000048638
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.019	0.2726	1
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0095	0.1115	0.4091
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0075	0.0773	0.2837
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	FL cytokine receptor	0.0075	0.0773	0.2837
Schistosoma mansoni	growth factor receptor-bound protein	0.0115	0.1462	0.5365
Schistosoma mansoni	GTPase activating protein	0.0115	0.1462	0.5365
Schistosoma mansoni	serine/threonine protein kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	suppressor of cytokine signaling	0.0115	0.1462	0.5365
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0115	0.1462	0.5365
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.019	0.2726	1
Onchocerca volvulus		0.0115	0.1462	0.1825
Giardia lamblia	Protein 21.1	0.0075	0.0773	0.0773
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0075	0.0773	0.1108
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Trypanosoma brucei	Pseudokinase, putative	0.0075	0.0773	0.5
Echinococcus granulosus	growth factor receptor bound protein 2	0.0115	0.1462	0.5365
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.019	0.2726	1
Schistosoma mansoni	serine/threonine protein kinase	0.0075	0.0773	0.2837
Onchocerca volvulus		0.0075	0.0773	0.0965
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0075	0.0773	0.000000048638
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0075	0.0773	0.2837
Giardia lamblia	Kinase, NEK	0.0075	0.0773	0.0773
Echinococcus multilocularis	SH2 motif	0.0115	0.1462	0.5365
Loa Loa (eye worm)	STAT protein	0.0115	0.1462	0.2095
Brugia malayi	hypothetical protein	0.0115	0.1462	0.2095
Trichomonas vaginalis	TKL family protein kinase	0.0075	0.0773	0.000000048638
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/INSR protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0063	0.0581	0.2133
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Brugia malayi	Sex muscle abnormal protein 5	0.0115	0.1462	0.2095
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0063	0.0581	0.2133
Brugia malayi	integrin-linked kinase	0.0075	0.0773	0.1108
Onchocerca volvulus		0.0075	0.0773	0.0965
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0075	0.0773	0.2837
Echinococcus granulosus	hypothetical protein	0.0115	0.1462	0.5365
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.019	0.2726	1
Onchocerca volvulus		0.0075	0.0773	0.0965
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0075	0.0773	0.2837
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	integrin linked protein kinase	0.0075	0.0773	0.2837
Plasmodium vivax	protein kinase, putative	0.0075	0.0773	1
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0075	0.0773	0.1108
Schistosoma mansoni	nck2/grb4	0.0115	0.1462	0.5365
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.019	0.2726	1
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0115	0.1462	0.5365
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Echinococcus granulosus	signal transduction protein lnk realted	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0075	0.0773	0.2837
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.1462	0.2095
Onchocerca volvulus		0.019	0.2726	0.3402
Echinococcus granulosus	epidermal growth factor receptor	0.0075	0.0773	0.2837
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0115	0.1462	0.5365
Echinococcus multilocularis	tensin	0.0115	0.1462	0.5365
Echinococcus multilocularis	SH2 motif	0.0115	0.1462	0.5365
Onchocerca volvulus		0.0115	0.1462	0.1825
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0075	0.0773	0.2837
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0075	0.0773	0.5
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.019	0.2726	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0115	0.1462	0.5365
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0075	0.0773	0.2837
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0075	0.0773	0.2837
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0075	0.0773	0.0965
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0115	0.1462	0.5365
Echinococcus granulosus	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine protein kinase csk	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FER protein kinase	0.019	0.2726	0.3905
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0115	0.1462	0.2095
Trichomonas vaginalis	TKL family protein kinase	0.0075	0.0773	0.000000048638
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0075	0.0773	0.1108
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Brugia malayi	SH2 domain containing protein	0.0115	0.1462	0.2095
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0075	0.0773	0.2837
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus multilocularis	protein tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	tensin-related	0.0115	0.1462	0.5365
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0075	0.0773	1
Brugia malayi	Raf kinase	0.0075	0.0773	0.1108
Brugia malayi	SRC-1	0.019	0.2726	0.3905
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Onchocerca volvulus	Tyrosine kinase homolog	0.0075	0.0773	0.0965
Loa Loa (eye worm)	hypothetical protein	0.0115	0.1462	0.2095
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.019	0.2726	1
Trypanosoma cruzi	protein kinase, putative	0.0075	0.0773	0.5
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0035	0.0103	0.0378
Treponema pallidum	fructose-bisphosphate aldolase	0.0619	1	0.5
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0063	0.0581	0.2133
Echinococcus granulosus	jumonji domain containing protein	0.004	0.0192	0.0704
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.019	0.2726	1
Echinococcus granulosus	activated cdc42 kinase 1	0.0075	0.0773	0.2837
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0075	0.0773	0.1108
Echinococcus granulosus	tyrosine kinase	0.019	0.2726	1
Plasmodium falciparum	protein kinase, putative	0.0075	0.0773	1
Brugia malayi	Furin-like cysteine rich region family protein	0.0075	0.0773	0.1108
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.019	0.2726	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Loa Loa (eye worm)	TK/FER protein kinase	0.0075	0.0773	0.1108
Echinococcus multilocularis		0.0115	0.1462	0.5365
Echinococcus granulosus	lysine specific demethylase 5A	0.0035	0.0103	0.0378
Echinococcus multilocularis	jumonji domain containing protein	0.004	0.0192	0.0704
Giardia lamblia	Fructose-bisphosphate aldolase	0.0619	1	1
Brugia malayi	Protein kinase domain containing protein	0.0075	0.0773	0.1108
Schistosoma mansoni	tyrosine kinase	0.019	0.2726	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Brugia malayi	Receptor family ligand binding region containing protein	0.0075	0.0773	0.1108
Loa Loa (eye worm)	TK protein kinase	0.0075	0.0773	0.1108
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0075	0.0773	1
Plasmodium falciparum	tyrosine kinase-like protein	0.0075	0.0773	1
Schistosoma mansoni	tyrosine kinase	0.0075	0.0773	0.2837
Brugia malayi	SH2 domain containing protein	0.019	0.2726	0.3905
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0063	0.0581	0.2133
Schistosoma mansoni	hypothetical protein	0.0075	0.0773	0.2837
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.019	0.2726	1
Schistosoma mansoni	protein kinase	0.0075	0.0773	0.2837
Plasmodium vivax	SET domain protein, putative	0.0063	0.0581	0.7519
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0115	0.1462	0.5365
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0075	0.0773	0.5
Echinococcus multilocularis	SH2 domain containing protein 7	0.0115	0.1462	0.5365
Brugia malayi	hypothetical protein	0.0075	0.0773	0.1108
Echinococcus multilocularis	tyrosine kinase	0.0075	0.0773	0.2837
Echinococcus granulosus	SH2 motif	0.0115	0.1462	0.5365

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2354517

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1757380