Detailed information for compound 1757536

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 536.702 | Formula: C32H44N2O5
  • H donors: 1 H acceptors: 3 LogP: 4.32 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)[C@@]12C[C@H](CC(=O)NCc3ccccc3)C(=O)N(C2=C[C@@H](O[C@@H]1C)C(C)(C)C)CCC1=CCCCC1
  • InChi: 1S/C32H44N2O5/c1-22-32(30(37)38-5)20-25(18-28(35)33-21-24-14-10-7-11-15-24)29(36)34(17-16-23-12-8-6-9-13-23)26(32)19-27(39-22)31(2,3)4/h7,10-12,14-15,19,22,25,27H,6,8-9,13,16-18,20-21H2,1-5H3,(H,33,35)/t22-,25+,27-,32+/m1/s1
  • InChiKey: PIPYNSBMRCFRKC-PICMWPILSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0469 0.138
Loa Loa (eye worm) hypothetical protein 0.0064 0.0793 0.1234
Loa Loa (eye worm) RecQ helicase 0.0021 0.0164 0.0245
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0127 0.0541
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0302 0.1282
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0018 0.00000000022873
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0247 0.0376
Loa Loa (eye worm) hypothetical protein 0.0311 0.4452 0.6991
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Schistosoma mansoni zinc finger protein 0.0015 0.0076 0.0059
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.003
Loa Loa (eye worm) helicase 0.0011 0.0018 0.0016
Loa Loa (eye worm) AGC/PKN protein kinase 0.0082 0.107 0.167
Loa Loa (eye worm) hypothetical protein 0.0311 0.4452 0.6991
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0078
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0649 0.0641
Schistosoma mansoni cpg binding protein 0.0032 0.0325 0.0309
Brugia malayi hypothetical protein 0.0016 0.009 0.0128
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0127 0.0466
Schistosoma mansoni unc-13 (munc13) 0.0082 0.1064 0.1049
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0127 0.0432
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.107 0.1055
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0127 0.0466
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0075 0.0959 0.1495
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0063 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Schistosoma mansoni phosphoglycerate kinase 0.0169 0.2354 0.2341
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0418 0.1777
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0041
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.006 0.0256
Echinococcus granulosus bloom syndrome protein 0.0021 0.0164 0.0156
Loa Loa (eye worm) hypothetical protein 0.0038 0.0415 0.0639
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0027 0.0036
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Schistosoma mansoni zinc finger protein 0.0021 0.0163 0.0146
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0552 0.0544
Echinococcus multilocularis serine:threonine protein kinase N2 0.0238 0.3371 0.3365
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0394 0.1673
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0082 0.1064 0.1056
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0018 0.001
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0082 0.107 0.167
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0523 0.081
Entamoeba histolytica PH domain containing protein kinase, putative 0.0162 0.2254 0.9574
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0394 0.1673
Schistosoma mansoni inositol monophosphatase 0.0037 0.0394 0.0378
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0523 0.0507
Echinococcus multilocularis serine threonine protein kinase 0.0222 0.3147 0.3141
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0082 0.107 0.1062
Loa Loa (eye worm) hypothetical protein 0.0216 0.3057 0.4796
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0744 0.3081
Echinococcus multilocularis serine:threonine protein kinase 38 0.0082 0.107 0.1062
Trichomonas vaginalis rotamase, putative 0.0032 0.033 0.0965
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0075 0.0959 0.0944
Leishmania major phosphoglycerate kinase C, glycosomal 0.0169 0.2354 1
Echinococcus granulosus serine:threonine protein kinase N2 0.0082 0.107 0.1062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0127 0.0432
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0164 0.0156
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0075 0.0959 0.1495
Schistosoma mansoni rac gtpase activating protein 0.0075 0.0959 0.0944
Echinococcus multilocularis N chimaerin 0.0075 0.0959 0.0951
Echinococcus granulosus unc 13 munc13 0.0082 0.1064 0.1056
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0875 0.2599
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0018 0.0078
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0418 0.1229
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0418 0.1777
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0299 0.127
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0018 0.0042
Echinococcus granulosus protein kinase c iota type 0.025 0.3553 0.3547
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0242 0.1029
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0062 0.0769 0.3269
Brugia malayi CXXC zinc finger family protein 0.0029 0.0273 0.0416
Onchocerca volvulus 0.0047 0.0552 0.0855
Echinococcus granulosus myotubularin protein 13 0.0079 0.1028 0.102
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0127 0.0356
Brugia malayi hypothetical protein 0.0025 0.0221 0.0335
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0042 0.0467 0.045
Entamoeba histolytica protein kinase, putative 0.0087 0.1138 0.4817
Schistosoma mansoni protein kinase C 0.0082 0.1064 0.1049
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Brugia malayi RhoGAP domain containing protein 0.0075 0.0959 0.1495
Toxoplasma gondii exonuclease III APE 0.0019 0.0127 0.0541
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0127 0.0356
Brugia malayi Pre-SET motif family protein 0.003 0.0299 0.0457
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Loa Loa (eye worm) RasGEF domain-containing protein 0.0075 0.0959 0.1495
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.055 0.0534
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.008 0.1036 0.3081
Trypanosoma brucei ISWI complex protein 0.0015 0.0076 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0959 0.0944
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0649 0.0641
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0221 0.094
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0098 0.0082
Schistosoma mansoni intermediate filament proteins 0.0027 0.0247 0.0231
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Brugia malayi CHD4 protein 0.0015 0.0071 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Onchocerca volvulus 0.0216 0.3057 0.4796
Brugia malayi C1-like domain containing protein 0.0214 0.3023 0.4742
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0082 0.1064 0.1056
Loa Loa (eye worm) hypothetical protein 0.0054 0.0649 0.1008
Echinococcus multilocularis cpg binding protein 0.0032 0.0325 0.0317
Loa Loa (eye worm) hypothetical protein 0.044 0.6365 1
Plasmodium falciparum small ubiquitin-related modifier 0.003 0.0302 0.1214
Leishmania major DNA damage repair protein, putative 0.0012 0.0027 0.0114
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0042 0.0034
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0027 0.0114
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0469 0.138
Brugia malayi Phosphoglycerate kinase 0.0169 0.2354 0.369
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0127 0.0541
Onchocerca volvulus 0.0236 0.3344 0.5247
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0299 0.0291
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0042
Trypanosoma cruzi DNA polymerase eta, putative 0.0037 0.0401 0.1706
Treponema pallidum phosphoglycerate kinase 0.0169 0.2354 1
Schistosoma mansoni rotamase 0.0033 0.0342 0.0326
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.003
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0379 0.0371
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0523 0.081
Echinococcus granulosus protein kinase c eta type 0.0075 0.0959 0.0951
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0027 0.0114
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0027 0.0114
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.5866 0.5863
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0169 0.2354 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0257 0.0746
Schistosoma mansoni cpg binding protein 0.0029 0.0273 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.007 0.0184
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0649 0.0641
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0394 0.0386
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0101 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.4255 0.4245
Trypanosoma cruzi small ubiquitin protein, putative 0.003 0.0302 0.1282
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0012 0.0024 0.0024
Brugia malayi SET domain containing protein 0.0013 0.0044 0.0055
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0114 0.0317
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0169 0.2354 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0101 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0027 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Echinococcus granulosus chromobox protein 2 0.0011 0.0018 0.001
Echinococcus granulosus Rac GTPase activating protein 1 0.0075 0.0959 0.0951
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0302 0.088
Entamoeba histolytica diacylglycerol kinase, putative 0.0075 0.0959 0.4053
Echinococcus multilocularis myotubularin protein 13 0.0079 0.1028 0.102
Loa Loa (eye worm) SMO-1 protein 0.003 0.0302 0.0461
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0744 0.3081
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0552 0.0544
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0018 0.0029
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0018 0.003
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Entamoeba histolytica hypothetical protein 0.0011 0.0018 0.0042
Brugia malayi diacylglycerol kinase 0.0075 0.0959 0.1495
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0744 0.2769
Loa Loa (eye worm) AGC/NDR protein kinase 0.0082 0.107 0.167
Onchocerca volvulus 0.0027 0.0247 0.0376
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.107 0.1055
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0753 0.0745
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0177 0.2468 0.387
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0018 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0394 0.1155
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0744 0.316
Trypanosoma brucei rac serine-threonine kinase, putative 0.0087 0.1138 0.4836
Loa Loa (eye worm) hypothetical protein 0.0039 0.0425 0.0655
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.107 0.1055
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0206 0.0198
Brugia malayi Protein kinase domain containing protein 0.0082 0.107 0.167
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0042
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0744 0.0736
Brugia malayi Ubiquitin-like protein SMT3 0.003 0.0302 0.0461
Trichomonas vaginalis rotamase, putative 0.0033 0.0342 0.1
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0018 0.0078
Trypanosoma cruzi ISWI complex protein 0.0015 0.0076 0.0321
Trichomonas vaginalis AGC family protein kinase 0.0082 0.107 0.3182
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0552 0.0536
Plasmodium falciparum phosphoglycerate kinase 0.0169 0.2354 1
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0078
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Echinococcus granulosus dna polymerase eta 0.0064 0.0793 0.0785
Plasmodium vivax SET domain protein, putative 0.003 0.0299 0.1201
Brugia malayi diacylglycerol kinase 0.0075 0.0959 0.1495
Schistosoma mansoni hypothetical protein 0.0075 0.0959 0.0944
Onchocerca volvulus 0.0212 0.2989 0.4689
Loa Loa (eye worm) hypothetical protein 0.044 0.6365 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0042 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0342 0.1
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0169 0.2354 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0523 0.0515
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0042
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0523 0.0515
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Echinococcus granulosus Chromo domain 0.0011 0.0018 0.001
Echinococcus multilocularis expressed protein 0.0033 0.0342 0.0334
Plasmodium vivax phosphoglycerate kinase, putative 0.0169 0.2354 1
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0018 0.0016
Trypanosoma cruzi DNA polymerase eta, putative 0.0064 0.0793 0.3369
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0077 0.0993 0.0985
Echinococcus multilocularis unc 13 (munc13) 0.0082 0.1064 0.1056
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0342 0.0525
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0221 0.0869
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0075 0.0959 0.0951
Schistosoma mansoni hypothetical protein 0.0292 0.4171 0.4161
Echinococcus granulosus protein kinase C gamma type 0.0222 0.3147 0.3141
Echinococcus granulosus Diacylglycerol kinase theta 0.0075 0.0959 0.0951
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0075 0.0959 0.0951
Loa Loa (eye worm) raf kinase 0.0075 0.0959 0.1495
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0126 0.0462
Brugia malayi mbt repeat family protein 0.0047 0.0552 0.0855
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0394 0.0386
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0337 0.0942
Trichomonas vaginalis hypothetical protein 0.0011 0.0018 0.003
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0221 0.094
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0649 0.1008
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0082 0.107 0.1062
Loa Loa (eye worm) AGC/AKT protein kinase 0.0087 0.1138 0.1777
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Onchocerca volvulus 0.003 0.0301 0.046
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0018 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0242 0.1029
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0169 0.2354 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0027 0.0114
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0027 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Trypanosoma brucei unspecified product 0.0026 0.0242 0.1029
Brugia malayi Pre-SET motif family protein 0.0207 0.2921 0.4582
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0552 0.0536
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0523 0.0507
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0649 0.0633
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0753 0.0745
Echinococcus multilocularis geminin 0.0168 0.2343 0.2336
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.033 0.1403
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2921 0.4582
Loa Loa (eye worm) hypothetical protein 0.0082 0.1064 0.166
Trypanosoma brucei unspecified product 0.0026 0.0242 0.1029
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0418 0.0402
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0027 0.0114
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0127 0.0506
Brugia malayi Bromodomain containing protein 0.0038 0.0414 0.0638
Schistosoma mansoni hypothetical protein 0.0406 0.5866 0.5859
Loa Loa (eye worm) hypothetical protein 0.0012 0.0027 0.0029
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0394 0.1155
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0418 0.1229
Brugia malayi Protein kinase domain containing protein 0.0077 0.0993 0.1549
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0993 0.0978
Leishmania major DNA polymerase eta, putative 0.0064 0.0793 0.3369
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0394 0.1673
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0523 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.0993 0.0978
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.055 0.0542
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0744 0.0736
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0071 0.0054
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0297 0.4255 0.425
Echinococcus granulosus Small ubiquitin modifier 2 0.003 0.0302 0.0294
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0394 0.1577
Leishmania major DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Schistosoma mansoni ap endonuclease 0.0019 0.0127 0.0111
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0214 0.3023 0.4742
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0418 0.041
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0247 0.0376
Echinococcus multilocularis serine:threonine protein kinase N2 0.0082 0.107 0.1062
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0319 0.4584 0.7198
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0425 0.0655
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0018 0.0001
Schistosoma mansoni hypothetical protein 0.002 0.0154 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.107 0.1055
Echinococcus granulosus Chromobox protein 3 0.0011 0.0018 0.001
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0169 0.2354 1
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0127 0.0119
Echinococcus granulosus cpg binding protein 0.0032 0.0325 0.0317
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0418 0.041
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0744 0.0728
Echinococcus multilocularis musashi 0.0027 0.0247 0.0239
Brugia malayi Protein kinase domain containing protein 0.0082 0.107 0.167
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0875 0.2599
Trypanosoma cruzi ISWI complex protein 0.0015 0.0076 0.0321
Toxoplasma gondii diacylglycerol kinase, putative 0.0075 0.0959 0.4075
Onchocerca volvulus 0.0011 0.0018 0.0016
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0394 0.1673
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0744 0.316
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0418 0.0645
Brugia malayi p70 ribosomal S6 kinase beta 0.0082 0.107 0.167
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0082 0.107 0.167
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0221 0.094
Trichomonas vaginalis set domain proteins, putative 0.0236 0.3344 1
Echinococcus multilocularis Chromo domain 0.0011 0.0018 0.001
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0418 0.0402
Loa Loa (eye worm) runx1 0.0055 0.0668 0.1037
Toxoplasma gondii AGC kinase 0.0082 0.107 0.4545
Echinococcus multilocularis chromobox protein 1 0.0069 0.0875 0.0868
Echinococcus multilocularis microtubule associated protein 2 0.0685 1 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0702 0.2982
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0018 0.0078
Schistosoma mansoni lamin 0.0027 0.0247 0.0231
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0082 0.107 0.1062
Loa Loa (eye worm) MBCTL1 0.0054 0.0649 0.1008
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0418 0.1777
Echinococcus multilocularis protein kinase c eta type 0.0075 0.0959 0.0951
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Brugia malayi chromobox protein homolog 3 0.0039 0.0425 0.0655
Schistosoma mansoni diacylglycerol kinase theta 0.0075 0.0959 0.0944
Brugia malayi Protein kinase c protein 2 0.0217 0.307 0.4816
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0127 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0082 0.107 0.1062
Brugia malayi Variant SH3 domain containing protein 0.0075 0.0959 0.1495
Echinococcus multilocularis protein kinase c iota type 0.025 0.3553 0.3547
Echinococcus multilocularis Small ubiquitin modifier 2 0.003 0.0302 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.055 0.0534
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0101 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0552 0.0544
Brugia malayi Phosphoglycerate kinase 0.0062 0.0769 0.1197
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.033 0.1403
Schistosoma mansoni phosphoglycerate kinase 0.0169 0.2354 0.2341
Toxoplasma gondii small ubiquitin family modifier, putative 0.003 0.0302 0.1282
Brugia malayi Hr1 repeat family protein 0.0082 0.107 0.167
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0164 0.0468
Schistosoma mansoni serine/threonine kinase 0.0082 0.107 0.1055
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0018 0.0078
Onchocerca volvulus 0.0082 0.1064 0.166
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0142 0.1961 0.3072
Echinococcus granulosus serine:threonine protein kinase N2 0.0158 0.2185 0.2179
Loa Loa (eye worm) hypothetical protein 0.0169 0.2354 0.369
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0552 0.0544
Schistosoma mansoni chromobox protein 0.0011 0.0018 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Echinococcus granulosus lamin dm0 0.0027 0.0247 0.0239
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0763 0.0747
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0075 0.0959 0.0944
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.007 0.0184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0101 0.0145
Onchocerca volvulus 0.044 0.6365 1
Schistosoma mansoni diacylglycerol kinase theta 0.0075 0.0959 0.0944
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0071 0.0098
Trypanosoma brucei unspecified product 0.0038 0.0418 0.1777
Onchocerca volvulus 0.0029 0.0273 0.0416
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Loa Loa (eye worm) hypothetical protein 0.0012 0.0035 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0425 0.1249
Brugia malayi RhoGAP domain containing protein 0.0075 0.0959 0.1495
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0273 0.0416
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0075 0.0959 0.1495
Brugia malayi hypothetical protein 0.044 0.6365 1
Echinococcus multilocularis phosphoglycerate kinase 1 0.0169 0.2354 0.2347
Chlamydia trachomatis phosphoglycerate kinase 0.0169 0.2354 0.5
Brugia malayi protein kinase C II. 0.0319 0.4584 0.7198
Echinococcus multilocularis Rac GTPase activating protein 1 0.0075 0.0959 0.0951
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0169 0.2354 0.7032
Brugia malayi RhoGEF domain containing protein 0.0075 0.0959 0.1495
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0154 0.0229
Loa Loa (eye worm) hypothetical protein 0.0385 0.5561 0.8735
Leishmania major hypothetical protein, conserved 0.0015 0.0076 0.0321
Echinococcus granulosus N chimaerin 0.0075 0.0959 0.0951
Schistosoma mansoni serine/threonine protein kinase 0.0297 0.4255 0.4245
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.011 0.016
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Echinococcus multilocularis zinc finger protein 0.0021 0.0163 0.0154
Leishmania major hypothetical protein, conserved 0.0025 0.0221 0.094
Entamoeba histolytica protein kinase, putative 0.0087 0.1138 0.4817
Trypanosoma brucei phosphoglycerate kinase 0.0169 0.2354 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0418 0.0645
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0063 0.0086
Loa Loa (eye worm) hypothetical protein 0.0044 0.0502 0.0776
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.003 0.0302 0.0285
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0018 0.0016
Schistosoma mansoni hypothetical protein 0.0168 0.2343 0.233
Loa Loa (eye worm) hypothetical protein 0.007 0.0891 0.1388
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0077 0.0993 0.0985
Onchocerca volvulus 0.0137 0.188 0.2945
Schistosoma mansoni hypothetical protein 0.0015 0.0076 0.0059
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Onchocerca volvulus 0.0027 0.0247 0.0376
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0063 0.0191
Schistosoma mansoni DNA polymerase eta 0.0064 0.0793 0.0777
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0133 0.1823 0.1816
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0418 0.1682
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0744 0.0728
Loa Loa (eye worm) hypothetical protein 0.0026 0.024 0.0364
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0257 0.0746
Loa Loa (eye worm) hypothetical protein 0.0047 0.055 0.0851
Brugia malayi Protein kinase domain containing protein 0.0087 0.1138 0.1777
Echinococcus granulosus phosphoglycerate kinase 1 0.0169 0.2354 0.2347
Loa Loa (eye worm) hypothetical protein 0.0208 0.2931 0.4598
Trypanosoma brucei small ubiquitin-related modifier 0.003 0.0302 0.1282
Loa Loa (eye worm) hypothetical protein 0.0137 0.188 0.2945
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0552 0.0855
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0027 0.0114
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.0042
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0552 0.0536
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0206 0.019
Schistosoma mansoni lamin 0.0027 0.0247 0.0231
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0418 0.041
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0418 0.1307
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.033 0.1403
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0082 0.107 0.167
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.019 0.2671 0.2665
Entamoeba histolytica protein kinase, putative 0.0082 0.107 0.4525
Loa Loa (eye worm) hypothetical protein 0.0047 0.0552 0.0855
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0127 0.0541
Schistosoma mansoni chromobox protein 0.0069 0.0875 0.086
Trypanosoma brucei DNA polymerase eta, putative 0.0064 0.0793 0.3369
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0017 0.0008
Schistosoma mansoni atypical protein kinase C 0.0257 0.3654 0.3643
Schistosoma mansoni inositol monophosphatase 0.0037 0.0394 0.0378
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0018 0.001
Entamoeba histolytica diacylglycerol kinase, putative 0.0075 0.0959 0.4053
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0169 0.2354 0.7032
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0027 0.0114
Plasmodium vivax small ubiquitin-related modifier, putative 0.003 0.0302 0.1214
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Schistosoma mansoni bromodomain containing protein 0.0064 0.0805 0.079
Brugia malayi Bromodomain containing protein 0.0076 0.0978 0.1525
Onchocerca volvulus 0.0011 0.0018 0.0016
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0139 0.1914 0.2998
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0394 0.1673
Schistosoma mansoni vav2 0.0079 0.1028 0.1012
Brugia malayi protein kinase C3,putative 0.017 0.2367 0.3711
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0469 0.0724
Echinococcus multilocularis raf serine:threonine protein kinase 0.0075 0.0959 0.0951
Schistosoma mansoni chromobox protein 0.0069 0.0875 0.086
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0221 0.0869
Echinococcus granulosus dnaJ subfamily B 0.0406 0.5866 0.5863
Brugia malayi mbt repeat family protein 0.0047 0.0552 0.0855
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0164 0.0245
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0523 0.0515
Echinococcus granulosus lamin 0.0027 0.0247 0.0239
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Brugia malayi ImpB/MucB/SamB family protein 0.0064 0.0793 0.1234
Schistosoma mansoni serine/threonine protein kinase 0.0319 0.4584 0.4575
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0127 0.0541
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0082 0.107 0.167
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0101 0.0093
Schistosoma mansoni cpg binding protein 0.0032 0.0325 0.0309
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0114 0.0317
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0071 0.0062
Echinococcus granulosus dna polymerase kappa 0.0038 0.0418 0.041
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0018 0.0001
Trypanosoma brucei phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Echinococcus granulosus raf serine:threonine protein kinase 0.0075 0.0959 0.0951
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0214 0.3023 0.4742
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0071 0.0062
Echinococcus granulosus expressed protein 0.0033 0.0342 0.0334
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0394 0.1673
Schistosoma mansoni protein kinase C mu 0.0214 0.3023 0.3011
Giardia lamblia DINP protein human, muc B family 0.0038 0.0418 0.1682
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0394 0.1155
Entamoeba histolytica ubiquitin like protein 0.003 0.0302 0.1251
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Echinococcus granulosus NDR protein kinase 0.0082 0.107 0.1062
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0418 0.1747
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0379 0.0371
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0127 0.0119
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0042 0.0034
Leishmania major DNA polymerase eta, putative 0.0037 0.0401 0.1706
Echinococcus multilocularis RNA directed DNA polymerase 0.0133 0.1823 0.1816
Leishmania major DNA polymerase kappa, putative 0.0012 0.0027 0.0114
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0169 0.2354 1
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0875 0.1364
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0018 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Trypanosoma brucei phosphoglycerate kinase 0.0169 0.2354 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0301 0.046
Schistosoma mansoni lozenge 0.0055 0.0668 0.0652
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0127 0.0541
Loa Loa (eye worm) hypothetical protein 0.0075 0.0959 0.1495
Brugia malayi Pleckstrin Homology Domain 0.0079 0.1028 0.1603
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0082 0.107 0.1062
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0027 0.0114
Echinococcus granulosus zinc finger protein 0.0021 0.0163 0.0154
Loa Loa (eye worm) hypothetical protein 0.0079 0.1028 0.1603
Loa Loa (eye worm) inositol-1 0.0037 0.0394 0.0606
Loa Loa (eye worm) hypothetical protein 0.0025 0.0221 0.0335
Echinococcus granulosus protein kinase c epsilon type 0.0319 0.4584 0.4579
Onchocerca volvulus 0.0311 0.4452 0.6991
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0018 0.0016
Echinococcus multilocularis chromobox protein 1 0.0069 0.0875 0.0868
Echinococcus multilocularis Protein lozenge 0.0055 0.0668 0.066
Echinococcus multilocularis Diacylglycerol kinase theta 0.0075 0.0959 0.0951
Mycobacterium ulcerans phosphoglycerate kinase 0.0169 0.2354 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0063 0.0163
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0018 0.0001
Brugia malayi PHD-finger family protein 0.0026 0.0241 0.0366
Schistosoma mansoni unc-13 (munc13) 0.0082 0.1064 0.1049
Brugia malayi Ras association domain family 1 isoform A 0.0075 0.0959 0.1495
Echinococcus multilocularis protein kinase c epsilon type 0.0319 0.4584 0.4579
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0018 0.00000000022873
Echinococcus granulosus intermediate filament protein 0.0027 0.0247 0.0239
Loa Loa (eye worm) hypothetical protein 0.0212 0.2989 0.4689
Loa Loa (eye worm) hypothetical protein 0.0137 0.188 0.2945
Brugia malayi intermediate filament protein 0.0027 0.0247 0.0376
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0649 0.0641
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0037 0.0401 0.1706
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0418 0.1777
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0418 0.1682
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0744 0.3081
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0342 0.0525
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0018 0.003
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.055 0.0542
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0552 0.0855
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0221 0.0869
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0523 0.0507
Echinococcus granulosus RNA directed DNA polymerase 0.0133 0.1823 0.1816
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0082 0.107 0.1062
Schistosoma mansoni chromobox protein 0.0011 0.0018 0.0001
Trypanosoma brucei phosphoglycerate kinase 0.0062 0.0769 0.3269
Trichomonas vaginalis AGC family protein kinase 0.0082 0.107 0.3182
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0018 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0087 0.1138 0.3387
Echinococcus multilocularis dna polymerase eta 0.0064 0.0793 0.0785
Entamoeba histolytica phosphoglycerate kinase, putative 0.0169 0.2354 1
Schistosoma mansoni protein kinase C mu 0.0075 0.0959 0.0944
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0027 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0082 0.107 0.3182
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0164 0.0468
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0027 0.0114
Schistosoma mansoni hypothetical protein 0.0168 0.2343 0.233
Loa Loa (eye worm) hypothetical protein 0.004 0.045 0.0694
Brugia malayi Protein cec-1. 0.0011 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0393 0.5672 0.8909
Echinococcus multilocularis lamin 0.0027 0.0247 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0299 0.0282
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0018 0.003
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.033 0.1372
Giardia lamblia Phosphoglycerate kinase 0.0169 0.2354 1
Onchocerca volvulus 0.0042 0.0467 0.0721
Entamoeba histolytica hypothetical protein 0.0075 0.0959 0.4053
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0206 0.0198
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0425 0.1249
Echinococcus granulosus chromobox protein 1 0.0069 0.0875 0.0868
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0127 0.0187
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0017 0.0008
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0418 0.1777
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0769 0.3269
Echinococcus multilocularis lamin dm0 0.0027 0.0247 0.0239
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0247 0.0376
Brugia malayi Variant SH3 domain containing protein 0.0012 0.0024 0.0024
Brugia malayi Inositol-1 0.0037 0.0394 0.0606
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0027 0.0114
Loa Loa (eye worm) hypothetical protein 0.0011 0.0018 0.0016
Giardia lamblia Sentrin 0.003 0.0302 0.1182
Brugia malayi hypothetical protein 0.0011 0.0018 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.0247 0.0376
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0418 0.1307
Leishmania major phosphoglycerate kinase B, cytosolic 0.0169 0.2354 1
Brugia malayi Heterochromatin protein 1 0.0069 0.0875 0.1364
Entamoeba histolytica protein kinase, putative 0.0082 0.107 0.4525
Echinococcus granulosus Protein kinase C brain isozyme 0.0297 0.4255 0.425
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0027 0.0114
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0114 0.0317
Loa Loa (eye worm) hypothetical protein 0.0133 0.1823 0.2854
Echinococcus granulosus chromobox protein 1 0.0069 0.0875 0.0868
Schistosoma mansoni microtubule-associated protein tau 0.0685 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0221 0.094
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0242 0.1029
Brugia malayi polk-prov protein 0.0012 0.0027 0.0029
Schistosoma mansoni ap endonuclease 0.0019 0.0127 0.0111
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.033 0.1403
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0274 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0027 0.0114
Schistosoma mansoni hypothetical protein 0.0011 0.0018 0.0001
Echinococcus granulosus geminin 0.0168 0.2343 0.2336
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0394 0.1643
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.033 0.1403
Loa Loa (eye worm) hypothetical protein 0.0311 0.4452 0.6991
Echinococcus multilocularis chromobox protein 2 0.0011 0.0018 0.001
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0169 0.2354 1
Leishmania major small ubiquitin protein, putative 0.003 0.0302 0.1282
Echinococcus granulosus endonuclease exonuclease phosphatase 0.019 0.2671 0.2665

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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