Detailed information for compound 17597

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 305.438 | Formula: C16H23N3OS
  • H donors: 2 H acceptors: 3 LogP: 5.06 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Nc1snc(n1)c1cc(c(c(c1)C(C)(C)C)O)C(C)(C)C
  • InChi: 1S/C16H23N3OS/c1-15(2,3)10-7-9(13-18-14(17)21-19-13)8-11(12(10)20)16(4,5)6/h7-8,20H,1-6H3,(H2,17,18,19)
  • InChiKey: HYHIPGJKSYRVCB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Cyclooxygenase Starlite/ChEMBL References
Rattus norvegicus Arachidonate 5-lipoxygenase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum IPR001024,Lipoxygenase, LH2;IPR013819,Lipoxygenase, C-terminal,domain-containing Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma japonicum ko:K00461 arachidonate 5-lipoxygenase [EC1.13.11.34], putative Get druggable targets OG5_127482 All targets in OG5_127482
Schistosoma mansoni lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus multilocularis arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
Echinococcus granulosus arachidonate 5 lipoxygenase Get druggable targets OG5_127482 All targets in OG5_127482
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0078 0.0687
Brugia malayi G-protein coupled receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.008 0.0162
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0147 0.0447 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0017 0.0017
Echinococcus granulosus carboxylesterase 5A 0.0139 0.0422 0.0422
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0292 0.0925 0.0925
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0078 0.1246
Entamoeba histolytica vacuolar protein sorting 26 0.0022 0.0036 0.0238
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi MBOAT family protein 0.0022 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.004 0.0077
Brugia malayi Cathepsin L-like precursor 0.0023 0.004 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0118 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.0007 0.0007
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0022
Loa Loa (eye worm) MBOAT family protein 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0059 0.0158 0.0158
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Brugia malayi SPARC precursor 0.0059 0.0158 0.0158
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Schistosoma mansoni sterol O-acyltransferase 1 0.0225 0.0703 0.0703
Schistosoma mansoni nuclear hormone receptor 0.0023 0.004 0.004
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0096
Echinococcus granulosus cysteine protease 0.0018 0.0023 0.0023
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0078 0.1002
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0008 0.0008
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0055 0.0055
Brugia malayi Carboxylesterase family protein 0.0024 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0049 0.0126 0.0126
Echinococcus multilocularis cysteine protease 0.0035 0.0078 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0049 0.0126 0.0126
Schistosoma mansoni cpg binding protein 0.0031 0.0067 0.0067
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0067 0.0067
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0013 0.0013
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0089 0.0089
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0078 0.0078
Loa Loa (eye worm) cysteine protease 0.0035 0.0078 0.0078
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0116 0.0116
Schistosoma mansoni histone deacetylase 1 2 3 0.0031 0.0066 0.0066
Trypanosoma cruzi histone deacetylase, putative 0.0031 0.0066 0.0066
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0017 0.0017
Trypanosoma brucei protein kinase, putative 0.0052 0.0136 0.0136
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0056 0.0147 0.0147
Echinococcus multilocularis lamin dm0 0.0028 0.0055 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0029 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus allatostatin A receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0013 0.0007 0.0007
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0022 0.0036 0.0036
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0015 0.0015
Onchocerca volvulus 0.0032 0.0068 0.0869
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0027 0.0049
Brugia malayi G-protein coupled receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0995 0.3238 0.3238
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0042 0.0042
Echinococcus granulosus geminin 0.0174 0.0537 0.0537
Brugia malayi Protein kinase domain containing protein 0.0015 0.0014 0.0014
Onchocerca volvulus Chorion peroxidase homolog 0.0095 0.0277 0.36
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0022 0.0036 0.0036
Schistosoma mansoni 60S ribosomal protein L21 0.0011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.005 0.0127 0.0127
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0022 0.0036 0.0238
Schistosoma mansoni integrin alpha 0.0056 0.0149 0.0149
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0116 0.0116
Echinococcus granulosus cathepsin L 0.0018 0.0023 0.0023
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0158 0.0158
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0049 0.0126 0.0126
Leishmania major cathepsin L-like protease 0.0035 0.0078 0.0078
Schistosoma mansoni histone deacetylase 4 5 0.006 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0015 0.0014 0.0014
Echinococcus granulosus sterol regulatory element binding protein 0.0995 0.3238 0.3238
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0063 0.0124
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0067 0.0067
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Echinococcus multilocularis survival motor neuron protein 1 0.0243 0.0764 0.0764
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0158 0.3123
Brugia malayi Serotonin receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0089 0.018
Echinococcus multilocularis thyroid hormone receptor alpha 0.0049 0.0126 0.0126
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0027 0.0027
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0017 0.0342
Echinococcus granulosus lipoxygenase domain containing protein 0.0065 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Brugia malayi Cyclic-nucleotide gated cation channel 0.0013 0.0007 0.0007
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0018 0.0018
Schistosoma mansoni peroxidasin 0.0095 0.0277 0.0277
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0026 0.005 0.005
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0089 0.0089
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0026 0.005 0.005
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0015 0.0014 0.0014
Echinococcus multilocularis dnaJ subfamily B 0.0421 0.1347 0.1347
Plasmodium vivax histone deacetylase, putative 0.006 0.0162 0.3172
Echinococcus multilocularis histone deacetylase 7 0.006 0.0162 0.0162
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0178 0.0178
Loa Loa (eye worm) melatonin receptor type 1A 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0158 0.0158
Brugia malayi neuropeptide F receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0036 0.0815
Echinococcus granulosus histone deacetylase 7 0.006 0.0162 0.0162
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni coup transcription factor 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0001 0.0001
Schistosoma mansoni dihydrofolate reductase 0.0048 0.0121 0.0121
Schistosoma mansoni hypothetical protein 0.0174 0.0537 0.0537
Echinococcus multilocularis g-protein coupled receptor 0.0011 0.0001 0.0001
Brugia malayi Melatonin receptor type 1A 0.0011 0.0001 0.0001
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0017 0.0017
Trichomonas vaginalis set domain proteins, putative 0.0244 0.0767 0.1634
Schistosoma mansoni amine GPCR 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0024 0.0041 0.0041
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0126 0.0126
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.0068 0.0068
Schistosoma mansoni follistatin 0.0059 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Trypanosoma cruzi cruzipain precursor, putative 0.0132 0.0399 0.0399
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0023 0.0023
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0147 0.0447 0.0447
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.0277 0.0277
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0007 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0119 0.0119
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0086 0.0086
Echinococcus granulosus nuclear receptor nhr 48 0.0023 0.004 0.004
Plasmodium vivax histone deacetylase 2, putative 0.006 0.0162 0.3172
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1431 0.4672 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0116 0.0238
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0225 0.0703 0.0703
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.009 0.009
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0086 0.0248 0.0248
Schistosoma mansoni acetylcholinesterase 0.0024 0.0041 0.0041
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0089 0.0089
Loa Loa (eye worm) DR-78 0.0023 0.004 0.004
Schistosoma mansoni patched 1 0.0995 0.3238 0.3238
Onchocerca volvulus 0.0024 0.0041 0.0522
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0007 0.0007
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.0105 0.0216
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0041 0.0041
Echinococcus multilocularis serotonin transporter 0.0186 0.0577 0.0577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Leishmania major glycerol uptake protein, putative 0.0022 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0078 0.0687
Loa Loa (eye worm) hypothetical protein 0.0065 0.0177 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0036 0.0036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0119 0.0119
Trypanosoma brucei histone deacetylase, putative 0.006 0.0162 0.0162
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Echinococcus granulosus neuroligin 0.0024 0.0041 0.0041
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0248 0.322
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0022 0.0036 0.0036
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0026 0.005 0.005
Brugia malayi hypothetical protein 0.0243 0.0764 0.0764
Echinococcus multilocularis sex peptide receptor 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0024 0.0041 0.0522
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0108 0.2137
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Loa Loa (eye worm) solute carrier family 6 member 4 0.0186 0.0577 0.0577
Echinococcus granulosus death domain containing protein 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0013
Brugia malayi hypothetical protein 0.0032 0.0068 0.0068
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0091 0.0262 0.0262
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0048 0.0121 0.2703
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0165 0.0506 0.0506
Echinococcus multilocularis histone deacetylase 6 0.0066 0.0182 0.0182
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0126 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0021 0.0021
Schistosoma mansoni ap endonuclease 0.0019 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0136 0.0282
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Echinococcus multilocularis G-protein coupled receptor, putative 0.0011 0.0001 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0007 0.0007
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0158 0.3123
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0165 0.0506 0.0506
Echinococcus multilocularis integrin alpha ps 0.0027 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0011 0.0001 0.0001
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0011 0.0001 0.0001
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0011 0.0001 0.0001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0067 0.1325
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0036
Brugia malayi nuclear hormone receptor 0.0049 0.0126 0.0126
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0001 0.0001
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0017 0.0342
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0139 0.0422 0.0422
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0089 0.0181
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0015 0.0015
Onchocerca volvulus Peroxidasin homolog 0.0095 0.0277 0.36
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Trypanosoma brucei histone deacetylase 2 0.0031 0.0066 0.0066
Trypanosoma brucei histone deacetylase 1 0.0078 0.022 0.022
Loa Loa (eye worm) carboxylesterase 0.0024 0.0041 0.0041
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0043 0.0107 0.0107
Echinococcus granulosus voltage dependent calcium channel 0.0091 0.0262 0.0262
Brugia malayi Carboxylesterase family protein 0.0024 0.0041 0.0041
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Entamoeba histolytica hypothetical protein, conserved 0.0022 0.0036 0.0238
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0067 0.0067
Echinococcus multilocularis protein patched 0.0995 0.3238 0.3238
Brugia malayi hypothetical protein 0.0023 0.004 0.004
Echinococcus granulosus g protein coupled receptor 0.0011 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0203 0.0631 0.0631
Schistosoma mansoni terminal deoxycytidyl transferase 0.0015 0.0014 0.0014
Brugia malayi MH2 domain containing protein 0.0123 0.0368 0.0368
Schistosoma mansoni zinc finger protein 0.0023 0.004 0.004
Plasmodium falciparum histone deacetylase 2 0.006 0.0162 0.2953
Loa Loa (eye worm) hypothetical protein 0.0186 0.0577 0.0577
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0018 0.0024 0.0024
Echinococcus granulosus thymidylate synthase 0.0117 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0399 0.0399
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Leishmania major glycerol uptake protein, putative 0.0022 0.0036 0.0036
Echinococcus granulosus neuropeptide receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.305 1 1
Brugia malayi ecdysteroid receptor 0.0049 0.0126 0.0126
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0023 0.0096
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0001 0.0001
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.0068 0.0068
Brugia malayi isocitrate dehydrogenase 0.0016 0.0017 0.0017
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0011 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0042 0.0042
Echinococcus multilocularis geminin 0.0174 0.0537 0.0537
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0136 0.0136
Onchocerca volvulus 0.0095 0.0277 0.36
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.006 0.006
Schistosoma mansoni nuclear receptor 0.0023 0.004 0.004
Echinococcus multilocularis somatostatin receptor 0.0011 0.0001 0.0001
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0165 0.0506 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0049 0.0126 0.0126
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0017 0.0388
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0086 0.0248 0.0248
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0765
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0067 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0049 0.0126 0.0126
Echinococcus granulosus ecdysone induced protein 78C 0.0049 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0067 0.0067
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0015
Echinococcus granulosus neuropeptide s receptor 0.0484 0.1558 0.1558
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0032 0.0068 0.0068
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0007 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.044 0.044
Echinococcus multilocularis lipoxygenase domain containing protein 0.0065 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0013 0.0013
Loa Loa (eye worm) histone deacetylase 1 0.0078 0.022 0.022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0095 0.0277 0.0277
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Plasmodium falciparum transporter, putative 0.0032 0.0068 0.1038
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0147 0.0447 1
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0158 0.0158
Onchocerca volvulus 0.0086 0.0248 0.322
Echinococcus multilocularis dna polymerase eta 0.0015 0.0014 0.0014
Brugia malayi histone deacetylase 3 (HD3) 0.0078 0.022 0.022
Echinococcus multilocularis voltage dependent calcium channel 0.0091 0.0262 0.0262
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0041 0.0926
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0158 0.0158
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0011 0.0002 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0011 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0001 0.0001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0089 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0454 0.0454
Echinococcus multilocularis cpg binding protein 0.0031 0.0067 0.0067
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0186 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Plasmodium vivax histone deacetylase 1, putative 0.0078 0.022 0.4336
Loa Loa (eye worm) norepinephrine transporter 0.0186 0.0577 0.0577
Loa Loa (eye worm) TYRA-2 protein 0.0011 0.0001 0.0001
Echinococcus granulosus lamin 0.0028 0.0055 0.0055
Echinococcus multilocularis neuroligin 0.0024 0.0041 0.0041
Echinococcus granulosus integrin alpha 3 0.0027 0.0053 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0011 0.0001 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0108 0.0222
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.305 1 1
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0178 0.0178
Brugia malayi orphan nuclear receptor NR2E1 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0049 0.0126 0.0126
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0165 0.0506 1
Schistosoma mansoni integrin alpha-ps 0.0056 0.0149 0.0149
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0089 0.018
Brugia malayi hypothetical protein 0.0056 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0116 0.0116
Brugia malayi MBOAT family protein 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Echinococcus granulosus Ankyrin 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Echinococcus multilocularis Niemann Pick C1 protein 0.0995 0.3238 0.3238
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0007 0.0007
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0049 0.0126 0.0126
Schistosoma mansoni zinc finger protein 0.0022 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0086 0.0086
Brugia malayi steroid hormone receptor 0.0049 0.0126 0.0126
Loa Loa (eye worm) fibroinase 0.0035 0.0078 0.0078
Echinococcus multilocularis neuropeptide receptor 0.0011 0.0001 0.0001
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.0068 0.0068
Leishmania major glycerol uptake protein, putative 0.0022 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0085 0.0172
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0018 0.0018
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Echinococcus granulosus tachykinin peptides receptor 99D 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0026 0.005 0.005
Brugia malayi diacylglycerol acyltransferase 0.0022 0.0036 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0105
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0127 0.0127
Onchocerca volvulus 0.0023 0.004 0.051
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0007 0.0007
Brugia malayi nuclear hormone receptor family member nhr-6 0.0023 0.004 0.004
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0022 0.0036 0.0238
Leishmania major squalene monooxygenase-like protein 0.0161 0.0493 0.0493
Schistosoma mansoni growth hormone secretagogue receptor 0.0011 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0041 0.0041
Loa Loa (eye worm) carboxylesterase 0.0024 0.0041 0.0041
Brugia malayi tailless protein 0.0023 0.004 0.004
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0048 0.0121 0.0121
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0036 0.0036
Trypanosoma cruzi GUP1, putative 0.0022 0.0036 0.0036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.004 0.004
Brugia malayi Cytochrome P450 family protein 0.0029 0.006 0.006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.004 0.004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus histone deacetylase 1 0.0078 0.022 0.022
Schistosoma mansoni lamin 0.0028 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Schistosoma mansoni netrin receptor unc5 0.0015 0.0013 0.0013
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0017 0.0017
Echinococcus multilocularis integrin alpha 3 0.0027 0.0053 0.0053
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0066 0.0131
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0091 0.0262 0.0262
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Schistosoma mansoni sodium/chloride dependent transporter 0.0186 0.0577 0.0577
Brugia malayi Nuclear hormone receptor E75 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0136 0.0282
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0178 0.0178
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0178 0.0178
Brugia malayi G protein-coupled receptor 0.0011 0.0001 0.0001
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0017 0.0017
Loa Loa (eye worm) integrin alpha pat-2 0.0124 0.0373 0.0373
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0116 0.1088
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.305 1 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0011 0.0002 0.0002
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0078 0.1246
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0029 0.006 0.006
Trypanosoma cruzi histone deacetylase, putative 0.0031 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.0018
Onchocerca volvulus 0.0065 0.0177 0.2289
Brugia malayi hypothetical protein 0.0086 0.0248 0.0248
Brugia malayi RE15519p 0.0011 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0001 0.0001
Leishmania major histone deacetylase, putative 0.006 0.0162 0.0162
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0178 0.0178
Toxoplasma gondii hypothetical protein 0.0032 0.0068 0.1345
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis orexin receptor type 2 0.0011 0.0001 0.0001
Brugia malayi Cathepsin L-like precursor 0.0011 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0007 0.0007
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0015 0.0014 0.0014
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0022 0.0036 0.0683
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0136 0.0234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0155 0.0475 0.0475
Brugia malayi Dopamine receptor protein 1 0.0011 0.0001 0.0001
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0089 0.08
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.0105 0.0216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0049 0.0126 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0067
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0042 0.0101 0.0101
Echinococcus granulosus histone deacetylase 8 0.0031 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Brugia malayi Cytochrome P450 family protein 0.0029 0.006 0.006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0017 0.0017
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0257 0.0809 0.0809
Loa Loa (eye worm) calcium channel 0.0091 0.0262 0.0262
Brugia malayi cathepsin F-like cysteine proteinase 0.0011 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0007 0.0004
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0027 0.0513
Brugia malayi nuclear receptor NHR-88 0.0023 0.004 0.004
Brugia malayi Kelch motif family protein 0.0059 0.0157 0.0157
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0049 0.0126 0.0126
Plasmodium vivax multidomain scavenger receptor, putative 0.0065 0.0177 0.3475
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.1345
Echinococcus granulosus intermediate filament protein 0.0028 0.0055 0.0055
Schistosoma mansoni organic anion transporter 0.0086 0.0248 0.0248
Schistosoma mansoni neuropeptide f receptor 76f 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0061 0.0061
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0027 0.0208
Brugia malayi nuclear receptor NHR-67 0.0023 0.004 0.004
Onchocerca volvulus Dual oxidase homolog 0.0095 0.0277 0.36
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0136 0.0136
Brugia malayi Nuclear hormone receptor E75 0.0023 0.004 0.004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0013 0.0008 0.0008
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0013 0.0013
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0007 0.0004
Toxoplasma gondii histone deacetylase HDAC2 0.0078 0.022 0.4354
Brugia malayi sulfakinin receptor protein 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0022 0.0036 0.0036
Echinococcus granulosus sodium and chloride dependent glycine 0.0032 0.0068 0.0068
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0013 0.0007 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0032 0.0068 0.0068
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0015
Brugia malayi MAP kinase sur-1 0.0052 0.0136 0.0136
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0011 0.0001 0.0001
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0089 0.0089
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0248 0.0248
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0028 0.0055 0.0701
Echinococcus granulosus 7tm_1 domain containing protein 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0085 0.0172
Echinococcus multilocularis histone deacetylase 1 0.0078 0.022 0.022
Brugia malayi hypothetical protein 0.0086 0.0248 0.0248
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0055 0.0107
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0013 0.0007 0.0007
Onchocerca volvulus 0.0023 0.004 0.0509
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.0042 0.0042
Echinococcus multilocularis allatostatin A receptor 0.0011 0.0001 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.0023
Brugia malayi MBOAT family protein 0.0022 0.0036 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Mycobacterium tuberculosis Conserved hypothetical protein 0.0015 0.0014 0.0307
Loa Loa (eye worm) nuclear receptor NHR-67 0.0023 0.004 0.004
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0096 0.0877
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0029 0.0059 0.0059
Onchocerca volvulus 0.0022 0.0036 0.0453
Brugia malayi Cytochrome P450 family protein 0.0031 0.0065 0.0065
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0022 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0049 0.0126 0.0126
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0089 0.0089
Leishmania major protein kinase, putative 0.0013 0.0008 0.0008
Trypanosoma cruzi cruzipain precursor, putative 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0035 0.008 0.008
Trypanosoma cruzi histone deacetylase 1, putative 0.0078 0.022 0.022
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0091 0.0262 0.0262
Schistosoma mansoni myosin xvIII 0.0011 0.0001 0.0001
Brugia malayi intermediate filament protein 0.0028 0.0055 0.0055
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0059 0.0157 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Brugia malayi TAR-binding protein 0.0065 0.0178 0.0178
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0022 0.0036 0.0036
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.0953 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0089 0.0089
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.305 1 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0086 0.0086
Schistosoma mansoni lipoxygenase 0.0257 0.0809 0.0809
Plasmodium vivax vivapain-1 0.0018 0.0023 0.0419
Echinococcus multilocularis histone deacetylase 6 0.006 0.0162 0.0162
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0013
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0022 0.0036 0.0384
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.022 0.0462
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0089 0.0132
Giardia lamblia GTOR 0.0046 0.0116 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0091 0.0262 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0116 0.0238
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0041 0.0926
Leishmania major cathepsin L-like protease 0.0035 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0126 0.0378 0.0378
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0108 0.0222
Echinococcus granulosus histone deacetylase 6 0.006 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0128 0.0128
Echinococcus multilocularis protein dispatched 1 0.0995 0.3238 0.3238
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0055 0.0055
Echinococcus granulosus cpg binding protein 0.0031 0.0067 0.0067
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0067 0.0067
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0001 0.0001
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0032 0.0068 0.0068
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0001 0.0001
Trypanosoma cruzi glycerol uptake protein, putative 0.0022 0.0036 0.0036
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0015
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0011 0.0001 0.0001
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0011 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0049 0.0126 0.0126
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0001 0.0001
Schistosoma mansoni cathepsin s 0.0011 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0059 0.0157 0.0157
Plasmodium vivax vivapain-2 0.0035 0.0078 0.1518
Echinococcus granulosus cathepsin l1 0.0035 0.0078 0.0078
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0049 0.0126 0.0126
Leishmania major cathepsin L-like protease 0.0132 0.0399 0.0399
Brugia malayi Animal haem peroxidase family protein 0.0095 0.0277 0.0277
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0017 0.0017
Schistosoma mansoni survival motor neuron protein 0.005 0.0127 0.0127
Loa Loa (eye worm) CYP4Cod1 0.0029 0.006 0.006
Onchocerca volvulus 0.0049 0.0126 0.163
Plasmodium vivax vivapain-2 0.0035 0.0078 0.1518
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0023 0.0023
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0041 0.0041
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0136 0.0136
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0008 0.0008
Treponema pallidum fructose-bisphosphate aldolase 0.03 0.0953 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Schistosoma mansoni agrin 0.0059 0.0158 0.0158
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0116 0.0116
Echinococcus granulosus orexin receptor type 2 0.0011 0.0001 0.0001
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.305 1 1
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0027 0.0147
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0078 0.0078
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.004 0.0284
Brugia malayi Uncoordinated protein 44 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0036 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0119 0.0119
Schistosoma mansoni DNA polymerase eta 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Trypanosoma cruzi GUP1, putative 0.0022 0.0036 0.0036
Echinococcus granulosus thyroid hormone receptor alpha 0.0023 0.004 0.004
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0078 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Trypanosoma brucei DNA polymerase kappa, putative 0.0033 0.0071 0.0071
Brugia malayi Histone deacetylase family protein 0.006 0.0162 0.0162
Onchocerca volvulus 0.0023 0.004 0.051
Echinococcus granulosus g protein coupled receptor 0.0011 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0089 1
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0001 0.0001
Brugia malayi nuclear receptor RXR 0.0023 0.004 0.004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0011 0.0001 0.0001
Schistosoma mansoni histone deacetylase 0.0078 0.022 0.022
Echinococcus multilocularis thymidylate synthase 0.0117 0.0349 0.0349
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0119 0.0119
Schistosoma mansoni neuropeptide receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.0049 0.0126 0.0126
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0014 0.0014
Schistosoma mansoni biogenic amine receptor 0.0011 0.0001 0.0001
Echinococcus granulosus integrin alpha ps 0.0056 0.0149 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Brugia malayi nuclear hormone receptor 0.0023 0.004 0.004
Trypanosoma cruzi DNA polymerase eta, putative 0.0015 0.0014 0.0014
Echinococcus multilocularis lamin 0.0028 0.0055 0.0055
Brugia malayi Dihydrofolate reductase 0.0048 0.0121 0.0121
Echinococcus multilocularis integrin beta 2 0.0274 0.0865 0.0865
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0023 0.0023
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0116 0.1088
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0059 0.0158 0.2043
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0007 0.0007
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0041 0.0041
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0041 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0011 0.0002 0.0002
Brugia malayi Hhat protein 0.0022 0.0036 0.0036
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0089 0.0802
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.1345
Echinococcus granulosus peroxidasin 0.0095 0.0277 0.0277
Toxoplasma gondii protease inhibitor PI2 0.0059 0.0158 0.3123
Echinococcus granulosus Solute carrier organic anion transporter family 0.0086 0.0248 0.0248
Loa Loa (eye worm) histone deacetylase 11 0.0031 0.0066 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Echinococcus granulosus o acyltransferase membrane bound domain 0.0022 0.0036 0.0036
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0007 0.0004
Schistosoma mansoni voltage-gated cation channel 0.0091 0.0262 0.0262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Brugia malayi nuclear receptor RXR 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Onchocerca volvulus 0.0013 0.0007 0.0068
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0136 0.0136
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0049 0.0126 0.0126
Brugia malayi Nuclear hormone receptor-like 1 0.0049 0.0126 0.0126
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0022 0.0036 0.0036
Brugia malayi Inositol-1 0.0038 0.0089 0.0089
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0049 0.0126 0.0126
Leishmania major glycerol uptake protein, putative 0.0022 0.0036 0.0036
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0116 0.0116
Echinococcus granulosus dro:myosuppressin receptor 0.0011 0.0001 0.0001
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0085 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0158 0.3123
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Onchocerca volvulus 0.0086 0.0248 0.322
Trypanosoma cruzi cytochrome P450, putative 0.0029 0.006 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0021 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Schistosoma mansoni RAR-like nuclear receptor 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypoxia-induced factor 1 0.0155 0.0473 0.0473
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0007 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis G protein coupled receptor 139 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni sodium-dependent amino acid transporter 0.0032 0.0068 0.0068
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.0277 0.0277
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.004 0.051
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0023 0.004 0.004
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0002 0.0041
Echinococcus granulosus hypothetical protein 0.0011 0.0001 0.0001
Entamoeba histolytica cysteine protease, putative 0.0035 0.0078 0.0687
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0001 0.0001
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.1345
Schistosoma mansoni histone deacetylase hda2 0.0066 0.0182 0.0182
Loa Loa (eye worm) G-protein coupled receptor 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0116 0.0116
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0011 0.0001 0.0001
Brugia malayi dihydrofolate reductase family protein 0.0048 0.0121 0.0121
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0018 0.0018
Brugia malayi hypothetical protein 0.0095 0.0277 0.0277
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0027 0.0027
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0022 0.0036 0.0036
Onchocerca volvulus 0.0032 0.0068 0.0869
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0013 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0049 0.0126 0.0126
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0015
Schistosoma mansoni nuclear hormone receptor 0.0023 0.004 0.004
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0086 0.0248 0.322
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0002 0.0002
Echinococcus granulosus acetylcholinesterase 0.0139 0.0422 0.0422
Brugia malayi hypothetical protein 0.0065 0.0177 0.0177
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0007 0.0004
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0022 0.0036 0.0036
Toxoplasma gondii histone deacetylase HDAC1 0.006 0.0162 0.3195
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0164 0.3236
Loa Loa (eye worm) hypothetical protein 0.0186 0.0577 0.0577
Echinococcus granulosus dnaJ subfamily B 0.0421 0.1347 0.1347
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0067
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0027 0.0027
Onchocerca volvulus 0.0035 0.0078 0.1002
Echinococcus granulosus fmrfamide receptor 0.0011 0.0001 0.0001
Brugia malayi hypothetical protein 0.0023 0.004 0.004
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0041 0.0041
Brugia malayi Animal haem peroxidase family protein 0.0095 0.0277 0.0277
Mycobacterium ulcerans thymidylate synthase 0.0117 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0065 0.0065
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0096
Echinococcus granulosus integrin alpha ps 0.0027 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0065 0.0177 0.0177
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0011 0.0001 0.0001
Echinococcus granulosus alpha 1A adrenergic receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0089 0.0089
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0022 0.0036 0.0036
Schistosoma mansoni microtubule-associated protein tau 0.0709 0.2298 0.2298
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0013 0.0013
Loa Loa (eye worm) neuropeptide F receptor 0.0011 0.0001 0.0001
Echinococcus granulosus G protein coupled receptor 139 0.0011 0.0001 0.0001
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Brugia malayi Carboxylesterase family protein 0.0024 0.0041 0.0041
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0022 0.0036 0.0713
Brugia malayi hypothetical protein 0.0126 0.0378 0.0378
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Loa Loa (eye worm) hypothetical protein 0.0015 0.0014 0.0014
Loa Loa (eye worm) hhat protein 0.0022 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0178 0.0178
Schistosoma mansoni sodium/chloride dependent transporter 0.0032 0.0068 0.0068
Brugia malayi hypothetical protein 0.0168 0.0516 0.0516
Loa Loa (eye worm) acetyltransferase 0.0149 0.0454 0.0454
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0007 0.0007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0076 0.1695
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0186 0.0577 0.7516
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Brugia malayi PAS domain containing protein 0.005 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0091 0.0262 0.0262
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0041 0.0041
Echinococcus multilocularis g protein coupled receptor 0.0011 0.0001 0.0001
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0089 0.0089
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0043 0.0107 0.0107
Trypanosoma cruzi squalene monooxygenase, putative 0.0161 0.0493 0.0493
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0091 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0089 0.0181
Brugia malayi Animal haem peroxidase family protein 0.0095 0.0277 0.0277
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0007 0.0007
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0013 0.0007 0.0007
Brugia malayi neuropeptide F receptor 0.0011 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0011 0.0001 0.0001
Brugia malayi nuclear receptor NHR-88 0.0049 0.0126 0.0126
Chlamydia trachomatis dihydrofolate reductase 0.0048 0.0121 1
Echinococcus granulosus serotonin transporter 0.0186 0.0577 0.0577
Loa Loa (eye worm) histone deacetylase 3 0.0078 0.022 0.022
Loa Loa (eye worm) acetylcholinesterase 1 0.0139 0.0422 0.0422
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0108 0.0108
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.1431 0.4672 1
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0136 0.0136
Echinococcus multilocularis fmrfamide receptor 0.0011 0.0001 0.0001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.0068 0.0068
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0032 0.0068 0.0068
Brugia malayi Carboxylesterase family protein 0.0024 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0031 0.0067 0.0856
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0043 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0036
Echinococcus multilocularis histone deacetylase 3 0.0078 0.022 0.022
Toxoplasma gondii cathepsin CPL 0.0035 0.0078 0.1546
Echinococcus multilocularis peroxidasin 0.0095 0.0277 0.0277
Brugia malayi AKH receptor 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0037 0.0086 0.11
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0007 0.0004
Schistosoma mansoni rab6-interacting 0.0065 0.0177 0.0177
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0013 0.0007 0.0007
Echinococcus multilocularis integrin alpha ps 0.0056 0.0149 0.0149
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0027 0.0027
Echinococcus multilocularis voltage dependent calcium channel 0.0091 0.0262 0.0262
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0119 0.0119
Loa Loa (eye worm) nuclear hormone receptor 0.0023 0.004 0.004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0035 0.0078 0.1002
Echinococcus granulosus histone deacetylase 0.006 0.0162 0.0162
Brugia malayi Dopamine receptor 0.0011 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Plasmodium vivax amine transporter, putative 0.0032 0.0068 0.1316
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0007 0.0007
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0136 0.0136
Brugia malayi Doublecortin family protein 0.0065 0.0177 0.0177
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis sterol O acyltransferase 1 0.0225 0.0703 0.0703
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0017 0.0017
Plasmodium vivax SET domain protein, putative 0.0031 0.0067 0.1296
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0119 0.0119
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0023 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0139 0.0422 0.0422
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.305 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0035 0.0078 0.1002
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0136 0.0136
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Schistosoma mansoni inositol monophosphatase 0.0038 0.0089 0.0089
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0116 0.0116
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Treponema pallidum sodium- and chloride- dependent transporter 0.0186 0.0577 0.5944
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0007 0.0004
Loa Loa (eye worm) MBOAT family protein 0.0022 0.0036 0.0036
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0158 0.0158
Onchocerca volvulus 0.0024 0.0041 0.0522
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0011 0.0001 0.0001
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0105 0.0105
Toxoplasma gondii hypothetical protein 0.0016 0.0015 0.0302
Brugia malayi CXXC zinc finger family protein 0.003 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) hhat protein 0.0022 0.0036 0.0036
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0049 0.0126 0.0126
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0017 0.0017
Giardia lamblia DINP protein human, muc B family 0.0022 0.0036 0.0019
Loa Loa (eye worm) integrin beta-2 0.0374 0.1194 0.1194
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0091 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0022 0.0036 0.0238
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0049 0.0126 0.0126
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0023 0.0023
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Onchocerca volvulus 0.0065 0.0177 0.2289
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0027 0.0053 0.0053
Brugia malayi Carboxylesterase family protein 0.0139 0.0422 0.0422
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0013 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Onchocerca volvulus 0.0024 0.0041 0.0522
Brugia malayi RNA binding protein 0.0065 0.0178 0.0178
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0022 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0047 0.0118 0.0118
Brugia malayi Pre-SET motif family protein 0.0215 0.067 0.067
Leishmania major histone deacetylase, putative 0.006 0.0162 0.0162
Brugia malayi Cathepsin L-like precursor 0.0023 0.004 0.004
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0116 0.0116
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Trypanosoma brucei cytochrome P450, putative 0.0029 0.006 0.006
Mycobacterium ulcerans DNA polymerase IV 0.0043 0.0105 0.0105
Onchocerca volvulus 0.0095 0.0277 0.36
Plasmodium falciparum amino acid transporter, putative 0.0032 0.0068 0.1038
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0399 0.0399
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0007 0.0007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0049 0.0126 0.0126
Onchocerca volvulus 0.0035 0.0078 0.1002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Schistosoma mansoni opsin-like receptor 0.0011 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0055 0.0107
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0013 0.0013
Onchocerca volvulus 0.0095 0.0277 0.36
Echinococcus granulosus Niemann Pick C1 protein 0.0995 0.3238 0.3238
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0001 0.0001
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0022 0.0036 0.0036
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0368 0.0368
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0136 0.0282
Brugia malayi hypothetical protein 0.0155 0.0475 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Echinococcus granulosus o acyltransferase membrane bound domain 0.0022 0.0036 0.0036
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0031 0.0066 0.0066
Onchocerca volvulus Bile acid receptor homolog 0.0049 0.0126 0.163
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0023 0.004 0.004
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.0077 0.1522
Schistosoma mansoni hypothetical protein 0.0106 0.0314 0.0314
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0085 0.0172
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0008 0.0008
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.03 0.0953 1
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0147 0.0305
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0765
Mycobacterium leprae Possible regulatory protein 0.0013 0.0007 0.0149
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0086 0.0248 0.0248
Echinococcus multilocularis integrin alpha ps 0.0056 0.0149 0.0149
Trypanosoma brucei unspecified product 0.0036 0.0083 0.0083
Brugia malayi polk-prov protein 0.0033 0.0071 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0178 0.0178
Schistosoma mansoni histone deacetylase 4 5 0.006 0.0162 0.0162
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0067 0.0067
Toxoplasma gondii transporter, major facilitator family protein 0.0086 0.0248 0.4907
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0023 0.0111
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0022 0.0036 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Leishmania major histone deacetylase, putative 0.0078 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0049 0.0126 0.163
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0065 0.0177 0.0177
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0186 0.0577 0.0577
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0015
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0059 0.0158 0.0158
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0022 0.0036 0.0036
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0017 0.0017
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0126 0.0378 0.0378
Echinococcus granulosus sex peptide receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0089 0.0089
Brugia malayi hypothetical protein 0.0026 0.005 0.005
Echinococcus granulosus Nuclear hormone receptor HR96 0.0023 0.004 0.004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0174 0.0537 0.0537
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0178 0.0178
Echinococcus granulosus neuropeptide receptor 0.0011 0.0001 0.0001
Brugia malayi prostaglandin transporter 0.0086 0.0248 0.0248
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0089 0.0089
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0091 0.0262 0.0262
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0032 0.0068 0.5376
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0136 0.2694
Loa Loa (eye worm) hypothetical protein 0.0243 0.0764 0.0764
Giardia lamblia Fructose-bisphosphate aldolase 0.03 0.0953 0.1992
Brugia malayi Pre-SET motif family protein 0.0031 0.0067 0.0067
Trypanosoma cruzi histone deacetylase 1, putative 0.0078 0.022 0.022
Schistosoma mansoni opsin-like receptor 0.0011 0.0001 0.0001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0041 0.0041
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0027 0.0027
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.0068
Loa Loa (eye worm) serotonin transporter b 0.0186 0.0577 0.0577
Plasmodium falciparum histone deacetylase 1 0.0078 0.022 0.4154
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.006 0.006
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0096 0.0148
Onchocerca volvulus 0.0086 0.0248 0.322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0119 0.0119
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0178 0.0178
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0023 0.0023
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0023 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0089 0.0089
Echinococcus multilocularis Polycystic kidney disease protein 0.0065 0.0177 0.0177
Brugia malayi hypothetical protein 0.0059 0.0157 0.0157
Toxoplasma gondii hypothetical protein 0.0022 0.0036 0.0713
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0049 0.0126 0.0126
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0017 0.0017
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0023 0.0023
Schistosoma mansoni lipoxygenase 0.014 0.0426 0.0426
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0024 0.0041 0.0522
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0022 0.0036 0.0036
Plasmodium vivax unspecified product 0.0018 0.0023 0.0419
Schistosoma mansoni nuclear receptor 0.0023 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0078 0.0157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0162 0.0162
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0116 0.0116
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0108 0.2111
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.0277 0.0277
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0015 0.0015
Onchocerca volvulus Peroxidase homolog 0.0095 0.0277 0.36
Echinococcus multilocularis agrin 0.0059 0.0158 0.0158
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0089 0.1756
Schistosoma mansoni cpg binding protein 0.0031 0.0067 0.0067
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.005 0.005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Brugia malayi larval opioid receptor 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0037 0.0086 0.0086
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0011 0.0001 0.0001
Schistosoma mansoni intermediate filament proteins 0.0028 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.022 0.0462
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0013 0.0013
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Schistosoma mansoni adenoreceptor 0.0011 0.0001 0.0001
Onchocerca volvulus Peroxidase homolog 0.0095 0.0277 0.36
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0018 0.0018
Brugia malayi hypothetical protein 0.0037 0.0086 0.0086
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0015 0.0014 0.0014
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0085 0.0085
Brugia malayi MBOAT family protein 0.0022 0.0036 0.0036
Toxoplasma gondii histone deacetylase HDAC3 0.0078 0.022 0.4354
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus granulosus histone deacetylase 3 0.0078 0.022 0.022
Echinococcus granulosus cathepsin l1 0.0023 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0023 0.0039
Echinococcus granulosus 7TM GPCR rhodopsin 0.0011 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0085 0.0172
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0086 0.0086
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0995 0.3238 0.3238
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0049 0.0126 0.0126
Echinococcus granulosus o acyltransferase membrane bound domain 0.0022 0.0036 0.0036
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0011 0.0001 0.0001
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0158 0.3123
Trypanosoma cruzi histone deacetylase, putative 0.006 0.0162 0.0162
Schistosoma mansoni integrin alpha-ps 0.0029 0.006 0.006
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.005 0.005
Brugia malayi conserved hypotetical protein 0.0023 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0085 0.0172
Echinococcus granulosus histone deacetylase 6 0.0066 0.0182 0.0182
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0086 0.0086
Onchocerca volvulus 0.0155 0.0475 0.6181
Brugia malayi Carboxylesterase family protein 0.0139 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0023 0.004 0.004
Echinococcus granulosus lipoxygenase domain containing protein 0.0065 0.0177 0.0177
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0032 0.0068 0.0068
Trypanosoma brucei glycerol uptake protein, putative 0.0022 0.0036 0.0036
Echinococcus multilocularis sodium channel protein 0.0042 0.0101 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Hypothetical protein 0.0056 0.0147 0.3289
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.305 1 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0078 0.0078
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0213 0.0213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0078 0.0078
Schistosoma mansoni rab6-interacting 0.0065 0.0177 0.0177
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0049 0.0126 0.0126
Echinococcus multilocularis neuropeptide receptor A26 0.0484 0.1558 0.1558
Leishmania major glycerol uptake protein, putative 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.0036
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0108 0.2137
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0834 0.2707 0.2707
Loa Loa (eye worm) steroid hormone receptor 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Schistosoma mansoni peroxidasin 0.0095 0.0277 0.0277
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Schistosoma mansoni integrin beta subunit 0.0215 0.0672 0.0672
Echinococcus multilocularis follistatin 0.0059 0.0158 0.0158
Brugia malayi G protein-coupled receptor F59B2.13 0.0011 0.0001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Leishmania major cathepsin L-like protease 0.0035 0.0078 0.0078
Echinococcus multilocularis Ankyrin 0.0015 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0049 0.0126 0.0126
Schistosoma mansoni lamin 0.0028 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0244 0.0768 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0078 0.0157
Loa Loa (eye worm) hypothetical protein 0.0139 0.0422 0.0422
Schistosoma mansoni inositol monophosphatase 0.0038 0.0089 0.0089
Schistosoma mansoni opsin-like receptor 0.0011 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0136 0.0136
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0091 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi Blistered cuticle protein 3 0.0095 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Trypanosoma cruzi major cysteine proteinase, putative 0.0104 0.0306 0.0306
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0013 0.0013
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0022 0.0036 0.0036
Brugia malayi Peroxidasin 0.0095 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0078 0.022 0.022
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Brugia malayi ecdysone receptor 0.0023 0.004 0.004
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0013 0.0007 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0007 0.0004
Brugia malayi histone deacetylase 11 0.0031 0.0066 0.0066
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.305 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.067 0.067
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Brugia malayi Dopamine receptor protein 2 0.0011 0.0001 0.0001
Onchocerca volvulus 0.0035 0.0078 0.1002
Brugia malayi CHE-14 protein 0.0995 0.3238 0.3238
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1431 0.4672 1
Toxoplasma gondii histone deacetylase HDAC4 0.0031 0.0066 0.131
Echinococcus multilocularis histone deacetylase 8 0.0031 0.0066 0.0066
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0186 0.0577 0.0577
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0117 0.0349 0.7804
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0078 0.1002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0023 0.0023
Schistosoma mansoni biogenic amine receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0011 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0121 0.0362 0.0362
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0117 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni single-minded 0.005 0.0128 0.0128
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0041 0.0079
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0165 0.0506 0.0506
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0089 0.0089
Echinococcus multilocularis histone deacetylase 6 0.006 0.0162 0.0162
Echinococcus granulosus neuropeptide Y receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0086 0.0248 0.0248
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0011 0.0001 0.0001
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0007 0.0007
Loa Loa (eye worm) doublecortin family protein 0.0065 0.0177 0.0177
Plasmodium vivax histone deacetylase, putative 0.0031 0.0066 0.1282
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0765
Echinococcus granulosus follistatin 0.0059 0.0158 0.0158
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.0068
Echinococcus granulosus dna polymerase kappa 0.0043 0.0105 0.0105
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0136 0.0136
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0257 0.0809 0.0809
Loa Loa (eye worm) hypothetical protein 0.0013 0.0007 0.0007
Schistosoma mansoni nuclear receptor nhr-48 0.0023 0.004 0.004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0049 0.0126 0.0126
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0067 0.0067
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0116 0.0116
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.008 0.0162
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.0053
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0041 0.0041
Echinococcus multilocularis neuropeptide Y receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0078 0.0078
Brugia malayi cathepsin L-like precursor 0.0023 0.004 0.004
Trichomonas vaginalis porcupine, putative 0.0022 0.0036 0.0067
Brugia malayi histone deacetylase 1 (HD1) 0.0078 0.022 0.022
Treponema pallidum alginate O-acetylation protein (algI) 0.0022 0.0036 0.0093
Trypanosoma cruzi MFS transporter, putative 0.0086 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Echinococcus multilocularis histone deacetylase 0.006 0.0162 0.0162
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0165 0.0506 1
Leishmania major cathepsin L-like protease 0.0132 0.0399 0.0399
Onchocerca volvulus 0.0032 0.0068 0.0869
Brugia malayi Serotonin receptor 0.0011 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0032 0.0068 0.0068
Brugia malayi ORL1-like opioid receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) dihydrofolate reductase 0.0048 0.0121 0.0121
Echinococcus multilocularis lipoxygenase domain containing protein 0.0065 0.0177 0.0177
Onchocerca volvulus Huntingtin homolog 0.0126 0.0378 0.4918
Brugia malayi Histone deacetylase family protein 0.006 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0168 0.0516 0.0516
Onchocerca volvulus Peroxidasin homolog 0.0095 0.0277 0.36
Schistosoma mansoni histone deacetylase 0.0078 0.022 0.022
Onchocerca volvulus 0.0086 0.0248 0.322
Onchocerca volvulus Huntingtin homolog 0.0126 0.0378 0.4918
Echinococcus multilocularis FTZ F1 alpha 0.0049 0.0126 0.0126
Echinococcus multilocularis sterol regulatory element binding protein 0.0995 0.3238 0.3238
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) agrin synaptic family protein 0.0059 0.0158 0.0158
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0007 0.0004
Echinococcus multilocularis musashi 0.0028 0.0055 0.0055
Loa Loa (eye worm) RNA binding protein 0.0065 0.0178 0.0178
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0078 0.0078
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0027 0.0027
Brugia malayi Integrin beta pat-3 precursor 0.0374 0.1194 0.1194
Loa Loa (eye worm) MBOAT family protein 0.0022 0.0036 0.0036
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0015
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.1431 0.4672 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0213 0.0213
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0016 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0027 0.0027
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0013 0.0007 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0013 0.0013
Leishmania major DNA polymerase kappa, putative 0.0022 0.0036 0.0036
Leishmania major protein kinase, putative 0.0018 0.0025 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0068 0.1316
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Leishmania major cathepsin L-like protease 0.0132 0.0399 0.0399
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0017 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0116 0.0238
Onchocerca volvulus 0.003 0.0061 0.0778
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0089 0.0089
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0094 0.0191
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni biogenic amine receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0368 0.0368
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0089 0.0089
Trypanosoma cruzi glycerol uptake protein, putative 0.0022 0.0036 0.0036
Echinococcus granulosus tar DNA binding protein 0.0065 0.0178 0.0178
Toxoplasma gondii exonuclease III APE 0.0019 0.0027 0.0544
Leishmania major cytochrome p450-like protein 0.0029 0.006 0.006
Echinococcus granulosus acetylcholinesterase 0.0139 0.0422 0.0422
Schistosoma mansoni histone deacetylase hda2 0.0031 0.0066 0.0066
Schistosoma mansoni gliotactin 0.0024 0.0041 0.0041
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0454 0.0454
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.03 0.0953 0.2031
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0013 0.0008 0.0008
Echinococcus granulosus lamin dm0 0.0028 0.0055 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.004 0.0077
Echinococcus granulosus neuropeptide FF receptor 2 0.0011 0.0001 0.0001
Trypanosoma brucei histone deacetylase 4 0.006 0.0162 0.0162
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0022 0.0036 0.0713
Loa Loa (eye worm) ctsf protein 0.0035 0.0078 0.0078
Trypanosoma brucei squalene monooxygenase, putative 0.0161 0.0493 0.0493
Schistosoma mansoni loxhd1 0.0065 0.0177 0.0177
Schistosoma mansoni amine GPCR 0.0011 0.0001 0.0001
Echinococcus granulosus g protein coupled receptor 0.0011 0.0001 0.0001
Brugia malayi putative neuropeptide receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0089 0.0181
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0027 0.0053 0.0053
Leishmania major cathepsin L-like protease 0.0035 0.0078 0.0078
Echinococcus granulosus agrin 0.0059 0.0158 0.0158
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0248 0.0248
Loa Loa (eye worm) histone deacetylase 0.006 0.0162 0.0162
Echinococcus granulosus RUN 0.0065 0.0177 0.0177
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0422 0.0422
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0022 0.0036 0.0036
Leishmania major DNA polymerase eta, putative 0.0015 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.005
Plasmodium vivax vivapain-3 0.0018 0.0023 0.0419
Echinococcus granulosus g-protein coupled receptor 0.0011 0.0001 0.0001
Brugia malayi Tachykinin-like peptides receptor 99D 0.0011 0.0001 0.0001
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0023 0.0096
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.005 0.005
Brugia malayi follicle stimulating hormone receptor 0.0248 0.0779 0.0779
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0023 0.004 0.004
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0007 0.0007
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0048 0.0121 0.2703
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Brugia malayi thymidylate synthase 0.0117 0.0349 0.0349
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0032 0.0068 0.0068
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0013 0.0007 0.0007
Schistosoma mansoni amine GPCR 0.0011 0.0001 0.0001
Plasmodium falciparum LCCL domain-containing protein 0.0065 0.0177 0.3266
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0015
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0078 0.0078
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Trypanosoma brucei DNA polymerase eta, putative 0.0015 0.0014 0.0014
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.0105 0.0105
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0078 0.022 0.0462
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0096 0.1612
Echinococcus granulosus integrin beta 2 0.0274 0.0865 0.0865
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0001 0.0001
Plasmodium falciparum histone deacetylase, putative 0.006 0.0162 0.2953
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0027 0.0615
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Brugia malayi hypoxia-induced factor 1 0.0155 0.0473 0.0473
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0036 0.0067
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0023 0.004 0.051
Echinococcus granulosus neuropeptide receptor A26 0.0484 0.1558 0.1558
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0027 0.0027
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0061 0.0061
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0095 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0022
Entamoeba histolytica hypothetical protein 0.0037 0.0086 0.0765
Loa Loa (eye worm) blistered cuticle protein 3 0.0095 0.0277 0.0277
Brugia malayi Histone deacetylase 1 0.0078 0.022 0.022
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0011 0.0001 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0049 0.0126 0.0126
Onchocerca volvulus 0.0117 0.0349 0.4533
Brugia malayi Animal haem peroxidase family protein 0.0095 0.0277 0.0277
Echinococcus granulosus FTZ F1 alpha 0.0049 0.0126 0.0126
Onchocerca volvulus 0.0035 0.0078 0.1002
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0013 0.0013
Schistosoma mansoni cpg binding protein 0.003 0.0061 0.0061
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0248 0.322
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0049 0.0126 0.0126
Loa Loa (eye worm) thymidylate synthase 0.0117 0.0349 0.0349
Onchocerca volvulus 0.0035 0.0078 0.1002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0046 0.0088
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0078 0.1246
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0011 0.0001 0.0001
Echinococcus granulosus tm gpcr rhodopsin 0.0011 0.0001 0.0001
Echinococcus multilocularis hyperpolarization activated cyclic 0.0013 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0049 0.0126 0.0126
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0032 0.0068 0.0068
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0248 0.322
Trypanosoma cruzi squalene monooxygenase, putative 0.0161 0.0493 0.0493
Echinococcus multilocularis RUN 0.0065 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0421 0.1347 0.1347
Brugia malayi Death domain containing protein 0.0015 0.0013 0.0013
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0.0001 0.0001
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0158 0.0158
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0017 0.0017
Echinococcus multilocularis serotonin receptor 0.0011 0.0001 0.0001
Loa Loa (eye worm) inositol-1 0.0038 0.0089 0.0089
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0089 0.0089
Echinococcus granulosus dihydrofolate reductase 0.0048 0.0121 0.0121
Brugia malayi putative neuropeptide receptor NPR1 0.0011 0.0001 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0023 0.0096
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0086 0.0086
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0007 0.0004
Leishmania major hypothetical protein, conserved 0.0022 0.0036 0.0036
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.0041 0.0926
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni retinoic acid receptor RXR 0.0049 0.0126 0.0126
Echinococcus multilocularis cysteine protease 0.0035 0.0078 0.0078
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Echinococcus multilocularis microtubule associated protein 2 0.0709 0.2298 0.2298
Echinococcus multilocularis expressed protein 0.0059 0.0158 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0017 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Onchocerca volvulus 0.0028 0.0055 0.0701
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0026 0.005 0.005
Echinococcus granulosus single minded 2 0.004 0.0097 0.0097
Loa Loa (eye worm) histone deacetylase 7A 0.006 0.0162 0.0162
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Brugia malayi photoreceptor-specific nuclear receptor 0.0292 0.0925 0.0925
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0001 0.0001
Echinococcus granulosus histone deacetylase 6 0.006 0.0162 0.0162
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0.0001 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0011 0.0001 0.0001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0119 0.0119
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.305 1 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0022 0.0036 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0136 0.0136
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0027 0.0027
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.0779 0.0779
Loa Loa (eye worm) hypothetical protein 0.0086 0.0248 0.0248
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni ap endonuclease 0.0019 0.0027 0.0027
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0076 0.1695
Echinococcus multilocularis nuclear receptor nhr 48 0.0023 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0011 0.0001 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0174 0.0174
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0059 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0995 0.3238 0.3238
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0049 0.0126 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0049 0.0126 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Echinococcus multilocularis dihydrofolate reductase 0.0048 0.0121 0.0121
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0011 0.0001 0.0001
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0117 0.0349 0.7804
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0043 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0038 0.0089 0.0089
Leishmania major cathepsin L-like protease 0.0035 0.0078 0.0078
Toxoplasma gondii histone deacetylase HDAC5 0.0031 0.0067 0.1318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0078 0.0157
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0011 0.0001 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0132 0.0399 0.0399
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0054 0.0105
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0013 0.0007 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.0032 0.0068 0.0068
Trichomonas vaginalis histone deacetylase, putative 0.0078 0.022 0.0462
Echinococcus multilocularis serotonin receptor 0.0011 0.0001 0.0001
Echinococcus granulosus hyperpolarization activated cyclic 0.0013 0.0007 0.0007
Echinococcus granulosus somatostatin receptor 0.0011 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0995 0.3238 0.6928
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0078 0.0078
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.004 0.004
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0085 0.0085
Schistosoma mansoni amine GPCR 0.0011 0.0001 0.0001
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0057 0.0153 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0105 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0132 0.0399 0.0399
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0078 0.0078
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0022 0.0036 0.0036
Trypanosoma brucei glycerol uptake protein, putative 0.0022 0.0036 0.0036
Echinococcus granulosus Protein patched homolog 1 0.0995 0.3238 0.3238
Echinococcus multilocularis dro:myosuppressin receptor 0.0011 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.0068
Brugia malayi Steroid receptor seven-up type 2 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0049 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0029 0.006 0.006
Entamoeba histolytica cysteine protease, putative 0.0018 0.0023 0.0096
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0049 0.0126 0.0126
Brugia malayi nuclear hormone receptor family member odr-7 0.0023 0.004 0.004
Schistosoma mansoni polycystin 1-related 0.0065 0.0177 0.0177
Onchocerca volvulus Protein ultraspiracle homolog 0.0049 0.0126 0.163
Echinococcus granulosus survival motor neuron protein 1 0.0243 0.0764 0.0764
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0078 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0055 0.0107
Brugia malayi hypothetical protein 0.0065 0.0177 0.0177
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0119 0.0119
Onchocerca volvulus Histone deacetylase 10 homolog 0.0031 0.0066 0.0846
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0049 0.0126 0.0126
Echinococcus granulosus neuropeptides capa receptor 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0077 0.0155
Brugia malayi Cathepsin L-like precursor 0.0035 0.0078 0.0078
Echinococcus multilocularis dna polymerase kappa 0.0043 0.0105 0.0105
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0022
Echinococcus multilocularis carboxylesterase 5A 0.0139 0.0422 0.0422
Toxoplasma gondii hypothetical protein 0.0032 0.0068 0.1345
Echinococcus granulosus microtubule associated protein 2 0.0709 0.2298 0.2298
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0041 0.0079
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0013 0.0013
Trypanosoma brucei histone deacetylase 3 0.006 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.004
Echinococcus granulosus dna polymerase eta 0.0015 0.0014 0.0014
Giardia lamblia Histone deacetylase 0.0078 0.022 0.0415
Entamoeba histolytica histone deacetylase, putative 0.0078 0.022 0.2199
Schistosoma mansoni neuropeptide receptor 0.0011 0.0001 0.0001
Schistosoma mansoni organic anion transporter 0.0086 0.0248 0.0248
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0454 0.0454
Brugia malayi ImpB/MucB/SamB family protein 0.0015 0.0014 0.0014
Echinococcus multilocularis neuropeptide s receptor 0.0484 0.1558 0.1558
Loa Loa (eye worm) carboxylesterase 0.0139 0.0422 0.0422
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Echinococcus multilocularis acetylcholinesterase 0.0139 0.0422 0.0422
Brugia malayi secreted modular calcium-binding protein 1 0.0059 0.0158 0.0158
Brugia malayi Animal haem peroxidase family protein 0.0095 0.0277 0.0277
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0013 0.0145
Echinococcus granulosus sterol O acyltransferase 1 0.0225 0.0703 0.0703
Echinococcus granulosus peptide allatostatin:somatostatin 0.0011 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0049 0.0126 0.0126
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0049 0.0126 0.0126
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0023 0.0023
Echinococcus granulosus serotonin receptor 0.0011 0.0001 0.0001
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0042 0.0821
Echinococcus multilocularis rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Trichomonas vaginalis transmembrane protein nessy, putative 0.0022 0.0036 0.0067
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.004 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0032 0.0068 0.0068
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0091 0.0262 0.0262
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0057 0.0153 0.0153
Brugia malayi MBOAT family protein 0.0022 0.0036 0.0036
Echinococcus granulosus Polycystic kidney disease protein 0.0065 0.0177 0.0177
Brugia malayi hypothetical protein 0.0011 0.0001 0.0001
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0089 0.0089
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0089 0.0089
Loa Loa (eye worm) animal heme peroxidase 0.0095 0.0277 0.0277
Echinococcus granulosus rhodopsin orphan GPCR 0.0011 0.0001 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0027 0.0049
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0078 0.1002
Brugia malayi Integrin alpha pat-2 precursor 0.0056 0.0149 0.0149
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0136 0.0282
Schistosoma mansoni sodium/chloride dependent transporter 0.0032 0.007 0.007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0041 0.0041
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0091 0.0262 0.0262
Echinococcus multilocularis cathepsin L 0.0018 0.0023 0.0023
Trypanosoma cruzi glycerol uptake protein, putative 0.0022 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0033 0.0071 0.0071
Leishmania major histone deacetylase, putative 0.0078 0.022 0.022
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0007 0.0007
Onchocerca volvulus 0.005 0.0127 0.164
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0022 0.0036 0.0036
Schistosoma mansoni histamine h1 receptor 0.0011 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0049 0.0126 0.0126
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.0041 0.0041
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0089 0.018
Brugia malayi GnHR receptor homolog 0.0011 0.0001 0.0001

Activities

Activity type Activity value Assay description Source Reference
(binding) 0 ChEMBL. 10197960
IC50 (binding) = 0.33 uM Evaluated in vitro for its inhibitory activity against 5-lipoxygenase ChEMBL. 1433181
IC50 (binding) = 0.33 uM Evaluated in vitro for its inhibitory activity against 5-lipoxygenase ChEMBL. 1433181
IC50 (binding) = 2.2 uM Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthase ChEMBL. 1433181
IC50 (binding) = 2.2 uM Evaluated in vitro for its inhibitory activity against Prostaglandin G/H synthase ChEMBL. 1433181
IC50 (binding) > 20 uM Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2) ChEMBL. 10197960
IC50 (binding) > 20 uM IC50 value against ovine Prostaglandin G/H synthase 1 ChEMBL. 10197960
IC50 (binding) > 20 uM Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2) ChEMBL. 10197960
IC50 (binding) > 20 uM IC50 value against ovine Prostaglandin G/H synthase 1 ChEMBL. 10197960
Ratio (binding) = 0.15 Ratio of IC50 against 5-LO to that of CO enzyme. ChEMBL. 1433181

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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