Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0078 | 0.5 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0078 | 0.5 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | c src tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0078 | 0.5 | 0.5 |
Brugia malayi | SRC-1 | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | SRC-1 | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0078 | 0.5 | 0.5 |
Brugia malayi | SH2 domain containing protein | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0078 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Echinococcus multilocularis | c src tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK protein kinase | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.5 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0078 | 0.5 | 0.5 |
Brugia malayi | SH2 domain containing protein | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0078 | 0.5 | 0.5 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0078 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0078 | 0.5 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Brugia malayi | Protein kinase domain containing protein | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0078 | 0.5 | 0.5 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0078 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Onchocerca volvulus | 0.0078 | 0.5 | 0.5 | |
Brugia malayi | protein-tyrosine kinase | 0.0078 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.