Detailed information for compound 1759897

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 519.772 | Formula: C23H20BrClN2O5
  • H donors: 0 H acceptors: 3 LogP: 3.95 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCOC(=O)[C@@H]1[C@H]2COc3c([C@@H]2N2[C@]1(C)C(=O)N(C2=O)c1ccc(cc1)Cl)cc(cc3)Br
  • InChi: 1S/C23H20BrClN2O5/c1-3-31-20(28)18-16-11-32-17-9-4-12(24)10-15(17)19(16)27-22(30)26(21(29)23(18,27)2)14-7-5-13(25)6-8-14/h4-10,16,18-19H,3,11H2,1-2H3/t16-,18+,19+,23+/m1/s1
  • InChiKey: IKKDKEBIRMANSH-LDQAXMLRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0118 0.0208 0.0203
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0071 0.0252
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Echinococcus multilocularis cpg binding protein 0.0037 0.0049 0.0077
Plasmodium falciparum JmjC domain-containing protein, putative 0.002 0.0015 0.0064
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0154
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0014 0.0005 0.0019
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0071 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0039 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0191 0.8753
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Toxoplasma gondii cathepsin CPL 0.0466 0.0888 0.9079
Loa Loa (eye worm) hypothetical protein 0.0466 0.0888 0.0888
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0054 0.1351
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0019 0.0069
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0025 0.0025
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.042
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0051 0.0172
Plasmodium falciparum serine repeat antigen 9 0.0118 0.0208 0.2258
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0484 0.1785
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.0178 0.18
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0554 0.1061 0.106
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.0017
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0014 0.0005 0.0004
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0051 0.0494
Echinococcus granulosus phd:f box containing protein 0.002 0.0015 0.0056
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0084 0.0083
Brugia malayi ecdysteroid receptor 0.0032 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0051 0.0051
Brugia malayi intermediate filament protein 0.0055 0.0084 0.0083
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0314 0.1165
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0118 0.0208 0.2258
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0122 0.1122
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Onchocerca volvulus Alhambra homolog 0.006 0.0095 0.009
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0039 0.0039
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0043 0.102
Toxoplasma gondii melibiase subfamily protein 0.0106 0.0184 0.1826
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0023 0.0176
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0027 0.0215
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0726 0.6839
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.001 0.0009
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0512 0.0978 0.3613
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Brugia malayi nuclear receptor RXR 0.0017 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0052 0.0079 0.0079
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0191 0.1332
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0198 0.0364 0.1349
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0191 0.1332
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0015 0.0045
Brugia malayi jmjC domain containing protein 0.0198 0.0364 0.0363
Plasmodium vivax unspecified product 0.0141 0.0253 0.2769
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0011 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0613 0.5763
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.012 0.019
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0006 0.0005
Loa Loa (eye worm) glutathione reductase 0.0048 0.0071 0.0071
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0014 0.0005 0.0019
Brugia malayi Cathepsin L-like cysteine proteinase 0.0325 0.0613 0.0612
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0045 0.0071
Entamoeba histolytica cysteine proteinase 1, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.006 0.0095 0.0095
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0554 0.1061 0.1061
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0208 0.0207
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0325 0.0613 0.2262
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0028 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Brugia malayi cathepsin F-like cysteine proteinase 0.0118 0.0208 0.0207
Onchocerca volvulus 0.0241 0.0448 0.0444
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.001 0.0018
Plasmodium falciparum serine repeat antigen 4 0.0118 0.0208 0.2258
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0005 0.0018
Onchocerca volvulus 0.0055 0.0084 0.0079
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Brugia malayi Papain family cysteine protease containing protein 0.0466 0.0888 0.0888
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0039 0.0127
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.124
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0051 0.0081
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0118 0.0208 0.2258
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0195 0.0713
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Echinococcus granulosus bloom syndrome protein 0.0025 0.0025 0.0094
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0314 0.0314
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.0508
Mycobacterium tuberculosis Probable hydrolase 0.0112 0.0195 0.1364
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Loa Loa (eye worm) cysteine protease 0.0466 0.0888 0.0888
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0118 0.0208 0.0754
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0019 0.0029
Leishmania major pyruvate kinase 0.0034 0.0043 0.0412
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0092
Onchocerca volvulus 0.0112 0.0195 0.019
Plasmodium vivax vivapain-2 0.0466 0.0888 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0118 0.0208 0.205
Echinococcus granulosus pyruvate kinase 0.0034 0.0043 0.0159
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0067
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0215 0.1508
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.0178 0.0178
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0095 0.0095
Brugia malayi hypothetical protein 0.0034 0.0043 0.0042
Leishmania major hypothetical protein, conserved 0.0112 0.0195 0.1971
Loa Loa (eye worm) hypothetical protein 0.0022 0.0019 0.0019
Mycobacterium leprae conserved hypothetical protein 0.0112 0.0195 0.8976
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0014 0.0005 0.0004
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0122 0.1036
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Trypanosoma cruzi cysteine protease, putative 0.0259 0.0484 0.1785
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0009 0.0033
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0043 0.0042
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0011 0.0017
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0112 0.0195 0.0194
Trypanosoma brucei cysteine peptidase C (CPC) 0.0512 0.0978 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0054 0.019
Schistosoma mansoni importin beta-1 0.0035 0.0045 0.0149
Brugia malayi Cathepsin L-like precursor 0.0141 0.0253 0.0252
Plasmodium falciparum serine repeat antigen 7 0.0118 0.0208 0.2258
Entamoeba histolytica Ran family GTPase 0.0026 0.0027 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0019 0.0019
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0259 0.0259
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0325 0.0613 0.5763
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0039 0.0038
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0006 0.0005
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0011 0.0011
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0943 0.149
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.001 0.0015
Echinococcus granulosus beta LACTamase domain containing family member 0.0112 0.0195 0.0723
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0006 0.0005
Giardia lamblia Cathepsin L-like protease 0.0118 0.0208 0.205
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0038 0.0059
Loa Loa (eye worm) hypothetical protein 0.0054 0.0082 0.0082
Leishmania major hypothetical protein, conserved 0.0052 0.0079 0.0782
Trichomonas vaginalis ran, putative 0.0026 0.0027 0.0228
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0182
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Echinococcus multilocularis tar DNA binding protein 0.0076 0.0126 0.02
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Brugia malayi hypothetical protein 0.0036 0.0048 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0034 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Brugia malayi hypothetical protein 0.0021 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0005 0.0018
Echinococcus multilocularis peregrin 0.006 0.0095 0.015
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.0462
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Echinococcus multilocularis cathepsin b 0.1391 0.2698 0.4263
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Brugia malayi Isocitrate dehydrogenase 0.0017 0.001 0.0009
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0051 0.0189
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Toxoplasma gondii thioredoxin reductase 0.0048 0.0071 0.0664
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0032 0.0276
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0025 0.0487
Entamoeba histolytica G protein alpha subunit, putative 0.0014 0.0005 0.0018
Brugia malayi cathepsin B-like cysteine proteinase 0.1391 0.2698 0.2697
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Schistosoma mansoni kinase 0.0055 0.0084 0.0295
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0048 0.0076
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0112 0.0195 0.0195
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0118 0.0208 0.2258
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.001 0.0025
Onchocerca volvulus 0.0112 0.0195 0.019
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0052 0.0192
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0051 0.0456
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.0888 0.1404
Mycobacterium ulcerans beta-lactamase 0.0112 0.0195 0.5625
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0076 0.0126 0.0126
Toxoplasma gondii exonuclease III APE 0.0039 0.0054 0.0492
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0019 0.0069
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0339 0.1243
Loa Loa (eye worm) hypothetical protein 0.0031 0.0038 0.0038
Brugia malayi steroid hormone receptor 0.0032 0.0039 0.0038
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0039 0.0039
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0067
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.001 0.0015
Giardia lamblia Pyruvate kinase 0.0017 0.0011 0.0015
Plasmodium falciparum serine repeat antigen 1 0.0118 0.0208 0.2258
Toxoplasma gondii aldehyde dehydrogenase 0.0185 0.0339 0.343
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0071 0.0697
Echinococcus multilocularis lysine specific demethylase 6a 0.002 0.0015 0.0024
Brugia malayi nuclear hormone receptor 0.0032 0.0039 0.0038
Schistosoma mansoni alpha-glucosidase 0.0149 0.0267 0.0975
Plasmodium falciparum serine repeat antigen 2 0.0118 0.0208 0.2258
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0314 0.0497
Loa Loa (eye worm) hypothetical protein 0.007 0.0115 0.0115
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0118 0.0208 0.2258
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0208 0.0208
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.0435 0.0435
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0054 0.0053
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.002 0.0015 0.0092
Plasmodium falciparum cysteine proteinase falcipain 3 0.0466 0.0888 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0006 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0014 0.0005 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.0441
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0009 0.0024
Echinococcus granulosus jumonji domain containing 1A 0.002 0.0015 0.0056
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0039 0.0062
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0039 0.0127
Brugia malayi Melibiase family protein 0.007 0.0115 0.0114
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0043
Plasmodium vivax unspecified product 0.0259 0.0484 0.5397
Echinococcus granulosus RUN 0.0021 0.0019 0.0069
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0221 0.0221
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0039 0.0034
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0215 0.1508
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.001 0.0094
Brugia malayi Pre-SET motif family protein 0.0031 0.0038 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Schistosoma mansoni zinc finger protein 0.0015 0.0006 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.0629 0.2332
Mycobacterium leprae Probable pyruvate kinase PykA 0.0034 0.0043 0.1033
Plasmodium vivax hypothetical protein, conserved 0.0112 0.0195 0.2112
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0023 0.0234
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0122 1
Echinococcus granulosus lamin dm0 0.0055 0.0084 0.031
Brugia malayi Inositol-1 0.0074 0.0122 0.0121
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.0548
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0019 0.0105
Schistosoma mansoni cathepsin F (C01 family) 0.0325 0.0613 0.2257
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Plasmodium falciparum serine repeat antigen 3 0.0118 0.0208 0.2258
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.3111
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0023 0.1237
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0142 0.0141
Plasmodium vivax vivapain-3 0.0259 0.0484 0.5397
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0054 0.02
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0043 0.0247
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0054 0.019
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0039 0.0038
Onchocerca volvulus 0.0147 0.0265 0.026
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0039 0.0127
Mycobacterium ulcerans hypothetical protein 0.0025 0.0025 0.0487
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.001 0.0036
Loa Loa (eye worm) hypothetical protein 0.0104 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0037 0.005 0.0168
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.0272
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0039 0.0062
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0006 0.0005
Schistosoma mansoni intermediate filament proteins 0.0055 0.0084 0.0292
Brugia malayi hypothetical protein 0.0014 0.0005 0.0004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0052 0.0462
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0005 0.0018
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0108 0.1044
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Trypanosoma brucei hypothetical protein, conserved 0.0112 0.0195 0.1991
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0009 0.0092
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0095 0.015
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0032 0.0039 0.0062
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0014 0.0005 0.0005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0006 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0051 0.0081
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0054 0.3976
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0208 0.0754
Toxoplasma gondii cathepsin CPC2 0.0118 0.0208 0.2076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0071 0.0262
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.005 0.0049
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0039 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Loa Loa (eye worm) fibroinase 0.0466 0.0888 0.0888
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0039 0.0038
Plasmodium falciparum serine repeat antigen 5 0.0118 0.0208 0.2258
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0032 0.0039 0.0145
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Giardia lamblia Pyruvate kinase 0.0034 0.0043 0.0348
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Schistosoma mansoni alpha-glucosidase 0.0149 0.0267 0.0975
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0112 0.0195 0.1364
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Plasmodium falciparum pyruvate kinase 0.0034 0.0043 0.0383
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0015 0.0154
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0118 0.0208 0.0207
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0215 0.1508
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Echinococcus granulosus cathepsin L 0.0118 0.0208 0.077
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Echinococcus granulosus tar DNA binding protein 0.0076 0.0126 0.0469
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.0178 0.0282
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0215 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0051 0.0189
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0084 0.0084
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0141 0.0253 0.0253
Plasmodium vivax vivapain-1 0.0259 0.0484 0.5397
Loa Loa (eye worm) hypothetical protein 0.1391 0.2698 0.2698
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0006 0.0005
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0208 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0484 0.4546
Schistosoma mansoni nuclear receptor 0.0015 0.0006 0.0005
Brugia malayi hypothetical protein 0.0017 0.001 0.0009
Plasmodium falciparum phd finger protein, putative 0.006 0.0095 0.0975
Onchocerca volvulus Cathepsin L homolog 0.0466 0.0888 0.0884
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0052 0.0462
Schistosoma mansoni pyruvate kinase 0.0034 0.0043 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0014 0.0005 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Entamoeba histolytica cysteine proteinase, putative 0.0325 0.0613 0.532
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0005 0.0018
Giardia lamblia Kinase, PLK 0.0103 0.0178 0.1745
Brugia malayi nuclear receptor NHR-88 0.0015 0.0006 0.0005
Plasmodium falciparum glutathione reductase 0.0048 0.0071 0.0697
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0052 0.0051
Brugia malayi PHD-finger family protein 0.0022 0.0019 0.0019
Onchocerca volvulus 0.0055 0.0084 0.0079
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0038 0.0038
Plasmodium falciparum serine repeat antigen 6 0.0118 0.0208 0.2258
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0051 0.0456
Brugia malayi beta-lactamase 0.0112 0.0195 0.0194
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0071 0.045
Schistosoma mansoni hypothetical protein 0.0021 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0043 0.0383
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0095 0.0916
Leishmania major hypothetical protein, conserved 0.0216 0.0399 0.406
Onchocerca volvulus 0.0466 0.0888 0.0884
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0039 0.0039
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0122 0.1188
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0314 0.0497
Schistosoma mansoni coup transcription factor 0.0032 0.0039 0.0127
Echinococcus multilocularis cysteine protease 0.0466 0.0888 0.1404
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0009 0.0024
Toxoplasma gondii histone lysine demethylase JMJD6a 0.002 0.0015 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0003 0.0025
Entamoeba histolytica hypothetical protein 0.0118 0.0208 0.1789
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0112 0.0195 0.1364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0157 0.0284 0.1038
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0034 0.0126
Loa Loa (eye worm) hypothetical protein 0.0147 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0043 0.0149
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0208 0.0761
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0019 0.003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0466 0.0888 0.0888
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Plasmodium falciparum thioredoxin reductase 0.0048 0.0071 0.0697
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0141 0.0253 0.0252
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0142 0.0508
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0014 0.0005 0.0019
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0006 0.001
Trypanosoma cruzi cruzipain precursor, putative 0.0466 0.0888 0.3286
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0095 0.0916
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Onchocerca volvulus 0.0325 0.0613 0.0608
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0039 0.0038
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0106 0.0184 0.029
Schistosoma mansoni cpg binding protein 0.0035 0.0045 0.0148
Echinococcus multilocularis pyruvate kinase 0.0034 0.0043 0.0068
Echinococcus granulosus cysteine protease 0.0259 0.0484 0.1793
Echinococcus multilocularis pyruvate kinase 0.0027 0.0029 0.0046
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Schistosoma mansoni polycystin 1-related 0.0021 0.0019 0.0051
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0259 0.0259
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.002 0.0117
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0162
Plasmodium falciparum cysteine proteinase falcipain 1 0.0259 0.0484 0.5397
Plasmodium vivax hypothetical protein, conserved 0.006 0.0095 0.0975
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0118 0.0208 0.2258
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0039 0.0038
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0201
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0082 0.0745
Brugia malayi glutathione reductase 0.0048 0.0071 0.007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0032 0.0276
Echinococcus granulosus cathepsin l1 0.0325 0.0613 0.227
Brugia malayi hypothetical protein 0.0015 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Echinococcus multilocularis cathepsin L cysteine protease 0.0466 0.0888 0.1404
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Echinococcus multilocularis cysteine protease 0.0466 0.0888 0.1404
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0518
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0208 0.2258
Schistosoma mansoni rab6-interacting 0.0021 0.0019 0.0051
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0484 0.4945
Brugia malayi CXXC zinc finger family protein 0.0035 0.0045 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0039 0.0145
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0079 0.0283
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0039 0.0062
Schistosoma mansoni cathepsin s 0.0141 0.0253 0.0921
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Brugia malayi fibroinase precursor 0.0118 0.0208 0.0207
Brugia malayi follicle stimulating hormone receptor 0.0234 0.0435 0.0434
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.1217
Leishmania major cysteine peptidase A (CPA) 0.0466 0.0888 0.9082
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0006 0.0023
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0015
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0014 0.0005 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0066 0.0106 0.4345
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0066 0.0106 0.0713
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica cysteine protease, putative 0.0466 0.0888 0.7728
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Plasmodium vivax unspecified product 0.0118 0.0208 0.2258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0039 0.0034
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0039 0.0062
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.0888 0.3281
Brugia malayi cathepsin F-like cysteine proteinase 0.0141 0.0253 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0048 0.0178
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0023 0.4123
Echinococcus granulosus snurportin 1 0.0372 0.0704 0.261
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.001 0.0036
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0014 0.0005 0.0005
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0182
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0051 0.0431
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0071 0.0112
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0043 0.038
Echinococcus granulosus importin subunit beta 1 0.0035 0.0045 0.0167
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0032 0.0109
Brugia malayi nuclear receptor RXR 0.0015 0.0006 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Schistosoma mansoni hypothetical protein 0.0017 0.0011 0.0022
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Leishmania major GTP-binding protein, putative 0.0026 0.0027 0.0248
Schistosoma mansoni hypothetical protein 0.006 0.0095 0.0335
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.205
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0124 0.0459
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.0178 0.0174
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0014 0.0005 0.0004
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.0025 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0011 0.0017
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0023 0.0102
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Brugia malayi hypothetical protein 0.0015 0.0006 0.0005
Brugia malayi Importin beta-1 subunit 0.0035 0.0045 0.0044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0051 0.0456
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0006 0.0023
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0054 0.0328
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Echinococcus multilocularis expressed protein 0.0014 0.0005 0.0008
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0115 0.0408
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0126 0.0223 0.0223
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0512 0.0978 0.3618
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0006 0.0006
Echinococcus granulosus cathepsin b 0.1391 0.2698 1
Loa Loa (eye worm) ctsf protein 0.0466 0.0888 0.0888
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.0025 0.0487
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0118 0.0208 0.2258
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0039 0.0127
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0039 0.0039
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0019 0.0029
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0025 0.0214
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.0025 0.0118
Brugia malayi cathepsin L-like cysteine proteinase 0.0118 0.0208 0.0207
Brugia malayi Thioredoxin reductase 0.0048 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0037 0.005 0.005
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0039 0.0038
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0118 0.0208 0.0208
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0005 0.0007
Plasmodium vivax glutathione reductase, putative 0.0048 0.0071 0.0697
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Giardia lamblia PHD finger protein 15 0.006 0.0095 0.0885
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0005 0.0017
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0704 0.0704
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0009 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0333 0.0629 0.0628
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0019
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0039 0.0145
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Brugia malayi nuclear receptor NHR-88 0.0032 0.0039 0.0038
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0023 0.0209
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0048 0.0161
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0126 0.0223 0.0223
Trypanosoma brucei glucosidase, putative 0.0038 0.0052 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Brugia malayi TAR-binding protein 0.0076 0.0126 0.0126
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Echinococcus multilocularis GPCR, family 2 0.0017 0.0011 0.0017
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0006 0.0023
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0027
Schistosoma mansoni loxhd1 0.0021 0.0019 0.0051
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0142 0.0224
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0051 0.0189
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0039 0.0062
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0123 0.0438
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0054 0.0446
Brugia malayi cathepsin L precursor 0.0118 0.0208 0.0207
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0015 0.0006 0.0005
Onchocerca volvulus 0.0466 0.0888 0.0884
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0191 0.1332
Brugia malayi cathepsin Z-like cysteine proteinase 0.0118 0.0208 0.0207
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0006 0.0001
Trypanosoma cruzi cysteine proteinase, putative 0.0259 0.0484 0.1785
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0005 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Mycobacterium tuberculosis Probable lipase LipE 0.0112 0.0195 0.1364
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0045 0.0456
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0027 0.0201
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.0025 0.0214
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0448 0.4209
Echinococcus multilocularis musashi 0.0055 0.0084 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0141 0.0253 0.0927
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.0888 0.7728
Giardia lamblia Cathepsin B precursor 0.0512 0.0978 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0039 0.0038
Leishmania major trypanothione reductase 0.0048 0.0071 0.0695
Trypanosoma cruzi cysteine peptidase, putative 0.0259 0.0484 0.1785
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0333 0.0629 0.2318
Brugia malayi ecdysone receptor 0.0015 0.0006 0.0005
Brugia malayi beta-lactamase family protein 0.0112 0.0195 0.0194
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0399 0.1469
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.0178 0.1659
Schistosoma mansoni aldehyde dehydrogenase 0.0185 0.0339 0.1243
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0208 0.1938
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0045 0.0456
Echinococcus granulosus JmjC domain containing protein 4 0.002 0.0015 0.0056
Loa Loa (eye worm) IKK protein kinase 0.5124 1 1
Trypanosoma brucei trypanothione reductase 0.0048 0.0071 0.0719
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0122 0.0441
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0185 0.0339 0.3452
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0182
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0118 0.0208 0.0208
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0019 0.0029
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.0178 0.1531
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0112 0.0195 0.5625
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0599 0.1149 1
Onchocerca volvulus 0.0466 0.0888 0.0884
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Mycobacterium ulcerans hypothetical protein 0.0025 0.0025 0.0487
Trypanosoma cruzi major cysteine proteinase, putative 0.0118 0.0208 0.0761
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0015 0.0097
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0106 0.0184 0.068
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0005 0.0008
Brugia malayi RNA, U transporter 1 0.0099 0.0171 0.017
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.0178 0.0178
Schistosoma mansoni hypothetical protein 0.0023 0.0023 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0039 0.0145
Plasmodium falciparum importin beta, putative 0.0035 0.0045 0.0405
Brugia malayi hypothetical protein 0.0017 0.001 0.0009
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0035
Schistosoma mansoni cpg binding protein 0.0037 0.0049 0.0162
Echinococcus granulosus expressed protein 0.0014 0.0005 0.0018
Loa Loa (eye worm) G protein alpha subunit 3 0.0014 0.0005 0.0005
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0014 0.0005 0.0019
Schistosoma mansoni cathepsin C 0.0118 0.0208 0.0754
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0118 0.0208 0.2258
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Brugia malayi hypothetical protein 0.0147 0.0265 0.0264
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.001 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0079 0.0283
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0094
Echinococcus granulosus cathepsin L cysteine proteinase 0.0466 0.0888 0.3293
Loa Loa (eye worm) RecQ helicase 0.0025 0.0025 0.0025
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0039 0.0034
Schistosoma mansoni hypothetical protein 0.0036 0.0048 0.0161
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0014 0.0005 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0038 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0039 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0106 0.0184 0.0663
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0713 0.1371 1
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Brugia malayi MH2 domain containing protein 0.0144 0.0259 0.0258
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Plasmodium vivax serine-repeat antigen (SERA) 0.0118 0.0208 0.2258
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Trichomonas vaginalis esterase, putative 0.0112 0.0195 0.1817
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0043 0.0149
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0011 0.001
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0599 0.1149 1
Schistosoma mansoni protein phosphatase 2C 0.002 0.0015 0.0038
Leishmania major hypothetical protein, conserved 0.002 0.0015 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0006 0.001
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Toxoplasma gondii cathepsin CPC1 0.0118 0.0208 0.2076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0118 0.0208 0.205
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0333 0.0629 0.0629
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0014 0.0005 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0124 0.0124
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0027 0.0026
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Loa Loa (eye worm) hypothetical protein 0.0125 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0009 0.0024
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0039 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0259 0.0484 0.4546
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0084 0.0084
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0023 0.042
Schistosoma mansoni hypothetical protein 0.002 0.0015 0.0039
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0014 0.0005 0.0008
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0112 0.0195 0.1364
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0017
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0185 0.0339 0.1258
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.002 0.0015 0.0038
Schistosoma mansoni cathepsin B (C01 family) 0.0118 0.0208 0.0754
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.001 0.0003
Loa Loa (eye worm) DR-78 0.0015 0.0006 0.0006
Brugia malayi Pre-SET motif family protein 0.0212 0.0391 0.039
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.001 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0009 0.0092
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0009 0.0024
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0128 0.0227 0.084
Plasmodium vivax SET domain protein, putative 0.0031 0.0038 0.0321
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.002 0.0015 0.0045
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0185 0.0339 0.0536
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0039 0.0127
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0051 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus granulosus GPCR family 2 0.0017 0.0011 0.004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0028 0.0028
Entamoeba histolytica cysteine proteinase, putative 0.0466 0.0888 0.7728
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0043 0.038
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0118 0.0208 0.1938
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0084 0.0083
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0027 0.01
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0038 0.0139
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0054 0.0508
Echinococcus granulosus cathepsin l cysteine peptidase 0.0466 0.0888 0.3293
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0118 0.0208 0.2258
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0069
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0118 0.0208 0.0754
Brugia malayi beta-lactamase family protein 0.0112 0.0195 0.0194
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0039 0.0127
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0054 1
Schistosoma mansoni inositol monophosphatase 0.0074 0.0122 0.0433
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0512 0.0978 1
Giardia lamblia Hypothetical protein 0.0118 0.0208 0.205
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0122 0.1122
Plasmodium vivax vivapain-2 0.0466 0.0888 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Echinococcus multilocularis lamin dm0 0.0055 0.0084 0.0132
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0026
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0006 0.0005
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Brugia malayi hypothetical protein 0.0052 0.0079 0.0078
Echinococcus multilocularis cathepsin L 0.0118 0.0208 0.0328
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0038 0.0323
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0178 0.0651
Echinococcus multilocularis lamin 0.0055 0.0084 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0178 0.0644
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0015 0.0039
Schistosoma mansoni lamin 0.0055 0.0084 0.0292
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0005 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Mycobacterium tuberculosis Conserved protein 0.0025 0.0025 0.0118
Brugia malayi hypothetical protein 0.0126 0.0223 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0023 0.0036
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0124 0.0442
Onchocerca volvulus 0.0466 0.0888 0.0884
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0009 0.0062
Chlamydia trachomatis pyruvate kinase 0.0034 0.0043 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0208 0.1789
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0054 0.0085
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0051 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Onchocerca volvulus 0.0032 0.0039 0.0034
Echinococcus multilocularis pyruvate kinase 0.0034 0.0043 0.0068
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0466 0.0888 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3247 0.6329 1
Onchocerca volvulus 0.0015 0.0006 0.0001
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0039 0.0145
Brugia malayi Doublecortin family protein 0.0021 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0141 0.0253 0.0253
Echinococcus granulosus cathepsin L cysteine protease 0.0259 0.0484 0.1793
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.001 0.0018
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0025 0.004
Onchocerca volvulus Cathepsin F homolog 0.0466 0.0888 0.0884
Loa Loa (eye worm) hypothetical protein 0.0035 0.0045 0.0045
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.0178 0.0661
Loa Loa (eye worm) jmjC domain-containing protein 0.002 0.0015 0.0015
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0006 0.0005
Echinococcus multilocularis jumonji domain containing 1A 0.002 0.0015 0.0024
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0259 0.0484 0.1778
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0122 0.3399
Loa Loa (eye worm) beta-lactamase 0.0112 0.0195 0.0195
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.0178 0.0651
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0039 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0427
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0032 0.0039 0.0038
Echinococcus granulosus cathepsin b 0.1391 0.2698 1
Echinococcus multilocularis phd:f box containing protein 0.002 0.0015 0.0024
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0191 0.1332
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0195 0.1817
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0035 0.011
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0484 0.0483
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0019 0.0105
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0025 0.0214
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0043 0.0038
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0391 0.0391
Trichomonas vaginalis D-aminoacylase, putative 0.0112 0.0195 0.1817
Trypanosoma brucei polo-like protein kinase 0.0103 0.0178 0.182
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0009 0.0009
Onchocerca volvulus 0.0466 0.0888 0.0884
Onchocerca volvulus 0.5124 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0011 0.001
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0014 0.0005 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0466 0.0888 1
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0014 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.0599 0.1149 0.1149
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1391 0.2698 1
Trypanosoma cruzi hypothetical protein, conserved 0.0112 0.0195 0.0713
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Giardia lamblia Cathepsin L-like protease 0.0118 0.0208 0.205
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Onchocerca volvulus 0.01 0.0172 0.0167
Entamoeba histolytica cysteine proteinase, putative 0.0259 0.0484 0.4197
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.0888 0.1404
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0142 0.0525
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.001 0.0018
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0118 0.0208 0.2258
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0141 0.0223
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0118 0.0208 0.2258
Echinococcus multilocularis beta LACTamase domain containing family member 0.0112 0.0195 0.0308
Loa Loa (eye worm) cathepsin B 0.0512 0.0978 0.0978
Echinococcus granulosus peregrin 0.006 0.0095 0.0352
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Onchocerca volvulus Huntingtin homolog 0.0126 0.0223 0.0218
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0039 0.0145
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.001 0.0025
Schistosoma mansoni phd/f-box containing protein 0.002 0.0015 0.0038
Echinococcus granulosus lamin 0.0055 0.0084 0.031
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0141 0.0524
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0039 0.0038
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Plasmodium vivax importin-beta 2, putative 0.0035 0.0045 0.0405
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0043 0.0043
Schistosoma mansoni alpha glucosidase 0.0038 0.0052 0.0174
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0043 0.038
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0052 0.0182
Mycobacterium ulcerans esterase/lipase LipP 0.0112 0.0195 0.5625
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0039 0.0127
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0466 0.0888 0.1404
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0011
Brugia malayi RNA recognition motif domain containing protein 0.0076 0.0126 0.0126
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0009 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.0629 0.0994
Onchocerca volvulus 0.0112 0.0195 0.019
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Schistosoma mansoni inositol monophosphatase 0.0074 0.0122 0.0433
Onchocerca volvulus 0.0031 0.0038 0.0033
Schistosoma mansoni lamin 0.0055 0.0084 0.0292
Loa Loa (eye worm) hypothetical protein 0.0024 0.0023 0.0023
Brugia malayi Bromodomain containing protein 0.006 0.0095 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0039 0.0062
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0032 0.0039 0.0039
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0084 0.0083
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0019 0.0069
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0006 0.0006
Brugia malayi isocitrate dehydrogenase 0.0017 0.001 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0076 0.0126 0.0452
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0006 0.0005
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0006 0.001
Brugia malayi jmjC domain containing protein 0.0075 0.0124 0.0123
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0051 0.0421
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0005 0.0045
Loa Loa (eye worm) hypothetical protein 0.0084 0.0142 0.0142
Echinococcus granulosus pyruvate kinase 0.0034 0.0043 0.0159
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.047
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0015 0.0097
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0006 0.0001
Leishmania major importin beta-1 subunit, putative 0.0028 0.0032 0.03
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Onchocerca volvulus Huntingtin homolog 0.0126 0.0223 0.0218
Plasmodium vivax JmjC domain containing protein 0.002 0.0015 0.0064
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Schistosoma mansoni ran 0.0026 0.0027 0.0082
Echinococcus granulosus cpg binding protein 0.0037 0.0049 0.018
Brugia malayi G-protein alpha subunit 0.0014 0.0005 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0259 0.0484 0.4945
Giardia lamblia Cathepsin L precursor 0.0118 0.0208 0.205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0019
Mycobacterium leprae Probable lipase LipE 0.0112 0.0195 0.8976
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0039 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0216 0.0399 0.1469
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.007 0.0115 0.1057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.0025 0.0487
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0023 0.0084
Entamoeba histolytica hypothetical protein 0.0024 0.0023 0.0178
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0179
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0128 0.0227 0.0358
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0118 0.0208 0.1789
Onchocerca volvulus 0.0015 0.0006 0.0001
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.002 0.0117
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0259 0.0484 0.1785
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0084
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Leishmania major pyruvate kinase 0.0034 0.0043 0.0412
Toxoplasma gondii ABC1 family protein 0.0112 0.0195 0.1944
Mycobacterium tuberculosis Probable esterase LipL 0.0112 0.0195 0.1364
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0045 0.0045
Schistosoma mansoni rab6-interacting 0.0021 0.0019 0.0051
Onchocerca volvulus 0.0021 0.0019 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.0025 0.0084
Onchocerca volvulus Cathepsin L homolog 0.0466 0.0888 0.0884
Schistosoma mansoni hypothetical protein 0.0494 0.0943 0.3484
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0052 0.0082
Mycobacterium tuberculosis Probable lipase LipD 0.0112 0.0195 0.1364
Onchocerca volvulus 0.0466 0.0888 0.0884
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Brugia malayi RNA binding protein 0.0076 0.0126 0.0126
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.001 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0118 0.0208 0.1938
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Echinococcus granulosus lysine specific demethylase 6a 0.002 0.0015 0.0056
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0006 0.0023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.001 0.001
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1391 0.2698 1
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0014 0.0005 0.0008
Echinococcus multilocularis JmjC domain containing protein 4 0.002 0.0015 0.0024
Trypanosoma brucei hypothetical protein, conserved 0.0216 0.0399 0.4075
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0023 0.0176
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0028 0.0045
Mycobacterium ulcerans hypothetical protein 0.0112 0.0195 0.5625
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0006 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0364 0.0688 0.6477
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0039 0.0039
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0118 0.0208 0.0208
Schistosoma mansoni cathepsin F (C01 family) 0.0466 0.0888 0.3281
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0118 0.0208 0.1938
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Schistosoma mansoni pyruvate kinase 0.0034 0.0043 0.0142
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0011 0.0048
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0106 0.0184 0.029
Loa Loa (eye worm) hypothetical protein 0.0112 0.0195 0.0195
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0118 0.0208 0.2258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Echinococcus granulosus cathepsin l1 0.0466 0.0888 0.3293
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0095 0.0352
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1391 0.2698 1
Schistosoma mansoni cathepsin S (C01 family) 0.0118 0.0208 0.0754
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0009 0.0062
Echinococcus granulosus intermediate filament protein 0.0055 0.0084 0.031
Mycobacterium tuberculosis Conserved protein 0.0112 0.0195 0.1364
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.0025 0.0094
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.001
Entamoeba histolytica cysteine proteinase 2 0.0259 0.0484 0.4197
Brugia malayi Cathepsin L-like precursor 0.0325 0.0613 0.0612
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0054 0.0461
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0466 0.0888 0.8371
Onchocerca volvulus 0.0021 0.0019 0.0014
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0014 0.0005 0.0019
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0054 0.0054
Schistosoma mansoni ap endonuclease 0.0039 0.0054 0.0182
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0943 0.3496
Schistosoma mansoni nuclear receptor 0.0015 0.0006 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.0466 0.0888 0.3286
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Toxoplasma gondii preprocathepsin c precursor, putative 0.0118 0.0208 0.2076
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0014 0.0005 0.0018
Brugia malayi Papain family cysteine protease containing protein 0.0118 0.0208 0.0207
Entamoeba histolytica cysteine protease, putative 0.0118 0.0208 0.1789
Entamoeba histolytica hypothetical protein 0.0036 0.0048 0.0395
Onchocerca volvulus Glucosylceramidase homolog 0.0364 0.0688 0.0684
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0052 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0118 0.0208 0.1938
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0038 0.0121
Loa Loa (eye worm) inositol-1 0.0074 0.0122 0.0122
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0115 0.0408
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0023 0.0158
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0027 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0039 0.0127
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0006 0.001
Brugia malayi conserved hypotetical protein 0.0015 0.0006 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0118 0.0208 0.0754
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0051 0.0179
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0466 0.0888 0.0888
Loa Loa (eye worm) hypothetical protein 0.0055 0.0084 0.0084
Loa Loa (eye worm) TAR-binding protein 0.0076 0.0126 0.0126
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0333 0.0629 0.0994
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Schistosoma mansoni lipoxygenase 0.0128 0.0227 0.0823
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0006 0.0006
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0191 0.1332
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0038 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.001 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0052 0.0462
Echinococcus multilocularis cathepsin L 0.0259 0.0484 0.0764
Brugia malayi Cathepsin L-like precursor 0.0466 0.0888 0.0888
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0039 0.0039
Toxoplasma gondii cathepsin B 0.0512 0.0978 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0195 0.0706
Echinococcus multilocularis cathepsin b 0.1391 0.2698 0.4263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0466 0.0888 0.8371
Trichomonas vaginalis glucosylceramidase, putative 0.0383 0.0726 0.6839
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Brugia malayi hypothetical protein 0.0021 0.0019 0.0018
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0079 0.0805
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0027 0.009
Brugia malayi tailless protein 0.0015 0.0006 0.0005
Onchocerca volvulus 0.0084 0.0142 0.0137
Giardia lamblia Encystation-specific protease 0.0118 0.0208 0.205
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0095 0.0335
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0118 0.0208 0.1938
Trypanosoma cruzi cruzipain precursor, putative 0.0141 0.0253 0.0927
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0118 0.0208 0.1938
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0118 0.0208 0.2258
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0035
Brugia malayi jmjC domain containing protein 0.002 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0483
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0466 0.0888 0.8371
Schistosoma mansoni pyruvate kinase 0.0017 0.0011 0.0022
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0112 0.0195 0.0706
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0185 0.0339 0.2425
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0039 0.0039
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0019 0.007
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0039 0.0062
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0054 0.0524
Mycobacterium ulcerans lipase LipD 0.0112 0.0195 0.5625
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0333 0.0629 0.2332
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0512 0.0978 0.9217
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0043 0.0436
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0023 0.0176
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.002 0.0015 0.015
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0122 0.0192
Giardia lamblia Cysteine protease 0.0118 0.0208 0.205
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0005 0.0018
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0122 0.0451
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0079 0.0793
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0054 0.0483
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0039 0.0127
Echinococcus granulosus pyruvate kinase 0.0017 0.0011 0.004
Schistosoma mansoni jumonji domain containing protein 0.002 0.0015 0.0038
Schistosoma mansoni lipoxygenase 0.0089 0.0151 0.0544
Brugia malayi cathepsin L-like precursor 0.0325 0.0613 0.0612
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Onchocerca volvulus 0.0466 0.0888 0.0884
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0014 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0372 0.0704 0.2596
Brugia malayi Cathepsin L-like precursor 0.0325 0.0613 0.0612
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0009 0.0067
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0009 0.0092
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0011 0.0017
Entamoeba histolytica hypothetical protein 0.0028 0.0032 0.0255
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0043 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.0054 0.0082 0.0745
Brugia malayi Papain family cysteine protease containing protein 0.0259 0.0484 0.0483
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0015 0.0015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0124 0.0442
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0466 0.0888 0.9084
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0023 0.0158
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0122 0.1122
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0005
Onchocerca volvulus 0.0035 0.0045 0.004
Plasmodium vivax hypothetical protein, conserved 0.0022 0.002 0.0117
Brugia malayi nuclear receptor NHR-67 0.0015 0.0006 0.0005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0198 0.0364 0.0575
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0052 0.0427
Onchocerca volvulus Cathepsin L homolog 0.0118 0.0208 0.0203
Leishmania major cathepsin L-like protease 0.0466 0.0888 0.9082
Echinococcus multilocularis snurportin 1 0.0372 0.0704 0.1112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0039 0.0038
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0005 0.0007
Brugia malayi nuclear hormone receptor 0.0015 0.0006 0.0005
Echinococcus multilocularis RUN 0.0021 0.0019 0.0029
Echinococcus multilocularis pyruvate kinase 0.0017 0.0011 0.0017
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0006 0.0023
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0045 0.04
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0039 0.0038
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0006 0.0023
Plasmodium falciparum serine repeat antigen 8 0.0118 0.0208 0.2258
Entamoeba histolytica cysteine protease, putative 0.0259 0.0484 0.4197
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0032 0.0276
Mycobacterium tuberculosis Probable reductase 0.0109 0.0191 0.1332
Echinococcus granulosus cathepsin L 0.0259 0.0484 0.1793
Brugia malayi AF-10 protein 0.002 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0325 0.0613 0.0613
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0052 0.0462
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0006 0.0005
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0039 0.0127
Brugia malayi PHD-finger family protein 0.006 0.0095 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0005 0.0018
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0043 0.0436
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0118 0.0208 0.1938
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0039 0.0127
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0039 0.0145
Loa Loa (eye worm) RNA binding protein 0.0076 0.0126 0.0126
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0014 0.0005 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0554 0.1061 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0118 0.0208 0.0754
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0039 0.0038
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.001 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0112 0.0195 0.1817
Mycobacterium ulcerans aldehyde dehydrogenase 0.0185 0.0339 1
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0079 0.0751
Schistosoma mansoni ran 0.0026 0.0027 0.0082
Giardia lamblia Cathepsin B precursor 0.0118 0.0208 0.205
Schistosoma mansoni phosphatidylserine receptor 0.002 0.0015 0.0038
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0314 0.0314

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.