Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | 0 % | Antireserpine activity (RES) of mice after peroral administration of 50 mg/kg of compound; NT is not tested | ChEMBL. | 2891853 |
Inhibition (functional) | 0 % | Antimaximal electroshock seizure (MES) activity in mice after peroral administration of 50 mg/kg of compound; NT is not tested | ChEMBL. | 2891853 |
Inhibition (functional) | 0 % | Antitremorine activity(TRM) of mice after peroral administration of 50 mg/kg of compound; NT is not tested | ChEMBL. | 2891853 |
Inhibition (functional) | < 30 % | Antiexploratory activity (EXPL) of mice determined by an antimex activity meter, 50 mg/kg of dose was administered perorally; No inhibition | ChEMBL. | 2891853 |
Inhibition (functional) | < 30 % | Antiexploratory activity (EXPL) of mice determined by an antimex activity meter, 50 mg/kg of dose was administered perorally; No inhibition | ChEMBL. | 2891853 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.