Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.1014 | 0.0453 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0191 | 0.0127 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.4439 | 0.5396 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0.0064 | 0.5 |
Trypanosoma brucei | ISWI complex protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.4439 | 0.5381 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.4722 | 0.6015 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.7379 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.8876 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4439 | 0.4403 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4722 | 0.4688 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0004 | 0.0082 | 0.1363 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.7379 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Onchocerca volvulus | 0.003 | 0.4439 | 0.5 | |
Trypanosoma cruzi | ISWI complex protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0711 | 0.0651 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.4722 | 0.6015 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0.0064 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0603 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4722 | 0.4688 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0603 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0004 | 0.0082 | 0.1363 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.1014 | 0.0453 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.7379 | 0.7362 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 20 uM | Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2) | ChEMBL. | 10197960 |
IC50 (binding) | > 20 uM | IC50 value against ovine Prostaglandin G/H synthase 1 | ChEMBL. | 10197960 |
IC50 (binding) | > 20 uM | Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2) | ChEMBL. | 10197960 |
IC50 (binding) | > 20 uM | IC50 value against ovine Prostaglandin G/H synthase 1 | ChEMBL. | 10197960 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.