TDR Targets

Basic information

Technical information

TDR Targets ID: 176101
Name: 3-(2-chlorophenothiazin-10-yl)propyl-[(7-meth oxy-2-oxochromen-4-yl)methyl]-dimethylazanium
MW: 508.052 | Formula: C28H28ClN2O3S+
H donors: 0 H acceptors: 1 LogP: 5.79 Rotable bonds: 7
Rule of 5 violations (Lipinski): 2
SMILES: COc1ccc2c(c1)oc(=O)cc2C[N+](CCCN1c2ccccc2Sc2c1cc(Cl)cc2)(C)C
InChi: 1S/C28H28ClN2O3S/c1-31(2,18-19-15-28(32)34-25-17-21(33-3)10-11-22(19)25)14-6-13-30-23-7-4-5-8-26(23)35-27-12-9-20(29)16-24(27)30/h4-5,7-12,15-17H,6,13-14,18H2,1-3H3/q+1
InChiKey: KWKDENFXTSYISJ-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-(2-chlorophenothiazin-10-yl)propyl-[(7-methoxy-2-oxo-chromen-4-yl)methyl]-dimethyl-ammonium
3-(2-chloro-10-phenothiazinyl)propyl-[(7-methoxy-2-oxo-1-benzopyran-4-yl)methyl]-dimethylammonium
3-(2-chlorophenothiazin-10-yl)propyl-[(7-methoxy-2-oxo-chromen-4-yl)methyl]-dimethyl-azanium
3-(2-chlorophenothiazin-10-yl)propyl-[(2-keto-7-methoxy-chromen-4-yl)methyl]-dimethyl-ammonium
3-(2-chloro-10-phenothiazinyl)propyl-[(7-methoxy-2-oxo-4-chromenyl)methyl]-dimethylammonium

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Trypanosoma cruzi	trypanothione reductase, putative	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Toxoplasma gondii	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Candida albicans	similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania donovani	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Neospora caninum	Glutathione reductase, related	Get druggable targets OG5_126785	All targets in OG5_126785
Brugia malayi	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania infantum	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Brugia malayi	Thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium falciparum	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium knowlesi	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium yoelii	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma congolense	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus multilocularis	thioredoxin glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Loa Loa (eye worm)	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma brucei	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium berghei	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium berghei	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium knowlesi	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	Get druggable targets OG5_126785	All targets in OG5_126785
Loa Loa (eye worm)	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Candida albicans	similar to S. cerevisiae GLR1 (YPL091W) glutathione oxidoreductase	Get druggable targets OG5_126785	All targets in OG5_126785
Echinococcus granulosus	thioredoxin glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium vivax	glutathione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium falciparum	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Schistosoma japonicum	ko:K00384 thioredoxin reductase (NADPH) [EC1.8.1.9], putative	Get druggable targets OG5_126785	All targets in OG5_126785
Cryptosporidium hominis	thioredoxin reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Babesia bovis	thiodoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania braziliensis	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Theileria parva	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Neospora caninum	MGC84926 protein, related	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania mexicana	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium vivax	thioredoxin reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Cryptosporidium parvum	thioredoxin reductase 1	Get druggable targets OG5_126785	All targets in OG5_126785
Plasmodium yoelii	glutathione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Leishmania major	trypanothione reductase	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma cruzi	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785
Trypanosoma brucei gambiense	trypanothione reductase, putative	Get druggable targets OG5_126785	All targets in OG5_126785

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Plasmodium falciparum	dihydrolipoyl dehydrogenase, apicoplast	trypanothione reductase, putative	492 aa	548 aa	21.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0079	0.5748	0.5748
Loa Loa (eye worm)	ctsf protein	0.0119	1	1
Plasmodium vivax	unspecified product	0.0061	0.3764	0.3764
Onchocerca volvulus	Cathepsin L homolog	0.0119	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0079	0.5748	0.5748
Trypanosoma cruzi	cysteine proteinase, putative	0.0061	0.3764	0.3764
Trypanosoma cruzi	cysteine peptidase, putative	0.0039	0.1391	0.1391
Echinococcus multilocularis	cysteine protease	0.0119	1	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.5748	0.5061
Onchocerca volvulus	Cathepsin F homolog	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0061	0.3764	0.3764
Echinococcus multilocularis	cathepsin L cysteine protease	0.0119	1	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0039	0.1391	0.1391
Brugia malayi	Cathepsin L-like precursor	0.0119	1	1
Echinococcus granulosus	cathepsin L	0.0061	0.3764	0.3764
Plasmodium vivax	unspecified product	0.0039	0.1391	0.1391
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0119	1	1
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0026	0	0.5
Brugia malayi	Thioredoxin reductase	0.0076	0.5394	0.5394
Onchocerca volvulus		0.0119	1	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0061	0.3764	0.3764
Giardia lamblia	NADH oxidase lateral transfer candidate	0.0026	0	0.5
Trypanosoma cruzi	cysteine peptidase, putative	0.0119	1	1
Onchocerca volvulus	Cathepsin L homolog	0.0119	1	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0061	0.3764	0.3764
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0119	1	1
Loa Loa (eye worm)	hypothetical protein	0.0119	1	1
Plasmodium falciparum	thioredoxin reductase	0.0076	0.5394	0.5394
Brugia malayi	cathepsin L-like precursor	0.0079	0.5748	0.5748
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0079	0.5748	0.5748
Leishmania major	cathepsin L-like protease	0.0119	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0119	1	1
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0076	0.5394	1
Brugia malayi	Papain family cysteine protease containing protein	0.0061	0.3764	0.3764
Leishmania major	cathepsin L-like protease	0.0119	1	1
Echinococcus granulosus	thioredoxin glutathione reductase	0.0076	0.5394	0.5394
Brugia malayi	glutathione reductase	0.0076	0.5394	0.5394
Mycobacterium ulcerans	flavoprotein disulfide reductase	0.0026	0	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Plasmodium vivax	vivapain-3	0.0061	0.3764	0.3764
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.0026	0	0.5
Plasmodium vivax	thioredoxin reductase, putative	0.0076	0.5394	0.5394
Toxoplasma gondii	thioredoxin reductase	0.0076	0.5394	0.5394
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Trypanosoma brucei	trypanothione reductase	0.0076	0.5394	0.5394
Echinococcus granulosus	cathepsin l1	0.0079	0.5748	0.5748
Echinococcus multilocularis	cathepsin L cysteine protease	0.0119	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0061	0.3764	0.3764
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Onchocerca volvulus		0.0119	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0119	1	1
Leishmania major	cathepsin L-like protease	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0119	1	1
Entamoeba histolytica	cysteine protease, putative	0.0119	1	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0061	0.3764	0.3764
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0039	0.1391	0.1391
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0061	0.3764	0.3764
Treponema pallidum	NADH oxidase	0.0026	0	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0119	1	1
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.0026	0	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0119	1	1
Leishmania major	cysteine peptidase A (CPA)	0.0119	1	1
Loa Loa (eye worm)	thioredoxin reductase	0.0076	0.5394	0.465
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.5748	0.5061
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0061	0.3764	0.3764
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0119	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0061	0.3764	0.3764
Schistosoma mansoni	cathepsin F (C01 family)	0.0079	0.5748	0.5748
Trypanosoma cruzi	trypanothione reductase, putative	0.0076	0.5394	0.5394
Plasmodium vivax	glutathione reductase, putative	0.0076	0.5394	0.5394
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0119	1	1
Onchocerca volvulus		0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Leishmania major	cathepsin L-like protease	0.0119	1	1
Echinococcus multilocularis	cathepsin L	0.0061	0.3764	0.3764
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0061	0.3764	0.3764
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0119	1	1
Echinococcus granulosus	cathepsin l1	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0061	0.3764	0.3764
Plasmodium vivax	vivapain-2	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0119	1	1
Leishmania major	cathepsin L-like protease	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0079	0.5748	0.5748
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0061	0.3764	0.3764
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0076	0.5394	0.5394
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Leishmania major	cathepsin L-like protease	0.0119	1	1
Echinococcus granulosus	cysteine protease	0.0061	0.3764	0.3764
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Brugia malayi	cathepsin F-like cysteine proteinase	0.0039	0.1391	0.1391
Onchocerca volvulus		0.0119	1	1
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase, LpdB	0.0026	0	0.5
Brugia malayi	Papain family cysteine protease containing protein	0.0061	0.3764	0.3764
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0119	1	1
Schistosoma mansoni	cathepsin s	0.0039	0.1391	0.1391
Leishmania major	trypanothione reductase	0.0076	0.5394	0.5394
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0079	0.5748	0.5748
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Loa Loa (eye worm)	cysteine protease	0.0119	1	1
Onchocerca volvulus		0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0119	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0119	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0119	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0119	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0079	0.5748	0.3182
Toxoplasma gondii	cathepsin CPL	0.0119	1	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0119	1	1
Trypanosoma cruzi	cysteine protease, putative	0.0061	0.3764	0.3764
Onchocerca volvulus		0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0119	1	1
Plasmodium falciparum	glutathione reductase	0.0076	0.5394	0.5394
Brugia malayi	Papain family cysteine protease containing protein	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Echinococcus multilocularis	cysteine protease	0.0119	1	1
Brugia malayi	Cathepsin L-like precursor	0.0039	0.1391	0.1391
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0026	0	0.5
Brugia malayi	Cathepsin L-like precursor	0.0079	0.5748	0.5748
Leishmania major	cathepsin L-like protease	0.0119	1	1
Leishmania major	cathepsin L-like protease	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0061	0.3764	0.3764
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0119	1	1
Onchocerca volvulus		0.0119	1	1
Loa Loa (eye worm)	glutathione reductase	0.0076	0.5394	0.465
Loa Loa (eye worm)	fibroinase	0.0119	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0119	1	1
Plasmodium vivax	vivapain-2	0.0119	1	1
Mycobacterium ulcerans	dihydrolipoamide dehydrogenase	0.0026	0	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0119	1	1
Plasmodium vivax	vivapain-1	0.0061	0.3764	0.3764
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0119	1	1
Loa Loa (eye worm)	hypothetical protein	0.0079	0.5748	0.5061

Activities

Activity type	Activity value	Assay description	Source	Reference
ED50 (functional)	= 3.11 ug ml-1	Antiparasitic activity against T. brucei	ChEMBL.	10956223
ED50 (functional)	= 3.11 ug ml-1	Antiparasitic activity against T. brucei	ChEMBL.	10956223
ED50 (functional)	= 5.28 uM	Antiparasitic activity against T. brucei	ChEMBL.	10956223
ED50 (functional)	= 5.28 uM	Antiparasitic activity against T. brucei	ChEMBL.	10956223
IC50 (binding)	= 2.95 uM	Inhibitory activity against T. cruzi trypanothione reductase	ChEMBL.	10956223
IC50 (binding)	= 2.95 uM	Inhibitory activity against T. cruzi trypanothione reductase	ChEMBL.	10956223
Ki (binding)	= 0.56 uM	Inhibitory activity against T. cruzi trypanothione reductase	ChEMBL.	10956223
Ki (binding)	= 0.56 uM	Inhibitory activity against T. cruzi trypanothione reductase	ChEMBL.	10956223

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL106769
PubChem: 10817172

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 176101