TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 546.649 | Formula: C30H42O9
H donors: 2 H acceptors: 3 LogP: 4.3 Rotable bonds: 2
Rule of 5 violations (Lipinski): 2
SMILES: OC[C@]12O[C@H]1[C@H]1[C@H]3OC45O[C@]1([C@H]1[C@@]6([C@@H]2O)O[C@](OC6=O)([C@@H]1[C@H](C)CCCCCCC5)C)[C@@H](C[C@@]3(O4)C(=C)C)C
InChi: 1S/C30H42O9/c1-15(2)26-13-17(4)29-19-21(26)35-28(38-26,39-29)12-10-8-6-7-9-11-16(3)18-20(29)30(24(33)36-25(18,5)37-30)23(32)27(14-31)22(19)34-27/h16-23,31-32H,1,6-14H2,2-5H3/t16-,17-,18-,19-,20+,21-,22+,23-,25+,26-,27+,28?,29-,30+/m1/s1
InChiKey: XRYQMTUHMOLDGS-STHVRRCPSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trypanosoma cruzi	protein kinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus granulosus	epidermal growth factor receptor	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/ACK protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	ankyrin repeat protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	raf serine:threonine protein kinase	0.0007	0.5	0.5
Giardia lamblia	Kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Blk	0.0007	0.5	0.5
Brugia malayi	SH2 domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase	0.0007	0.5	0.5
Trypanosoma cruzi	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/RYK protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0007	0.5	0.5
Toxoplasma gondii	protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0007	0.5	0.5
Echinococcus multilocularis	transfer RNA-Thr	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0007	0.5	0.5
Brugia malayi	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0007	0.5	0.5
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/INSR protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0007	0.5	0.5
Echinococcus granulosus	ephrin type A receptor 4 A	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0007	0.5	0.5
Brugia malayi	Tyrosine-protein kinase abl-1	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Giardia lamblia	Kinase, NEK	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Raf kinase	0.0007	0.5	0.5
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0007	0.5	0.5
Leishmania major	hypothetical protein, conserved	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus granulosus	activated cdc42 kinase 1	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Plasmodium falciparum	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Loa Loa (eye worm)	TK/ALK protein kinase	0.0007	0.5	0.5
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0007	0.5	0.5
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	AGC family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase pr2	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Plasmodium vivax	protein kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	insulin receptor	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Echinococcus multilocularis	heat shock protein 70	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/ABL protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein, conserved	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Leishmania major	protein kinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Entamoeba histolytica	receptor protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	integrin linked protein kinase	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	kinase suppressor of Ras 1	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	activated cdc42 kinase 1	0.0007	0.5	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0007	0.5	0.5
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Srms	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	activin receptor type	0.0007	0.5	0.5
Trichomonas vaginalis	STE family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Giardia lamblia	Protein 21.1	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0007	0.5	0.5
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0007	0.5	0.5
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0007	0.5	0.5
Toxoplasma gondii	STE kinase	0.0007	0.5	0.5
Echinococcus multilocularis	FL cytokine receptor	0.0007	0.5	0.5
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	c src tyrosine kinase	0.0007	0.5	0.5
Schistosoma mansoni	ephrin receptor	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	C-terminal src kinase protein 1	0.0007	0.5	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine kinase	0.0007	0.5	0.5
Echinococcus granulosus	epidermal growth factor receptor	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	receptor protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Brugia malayi	integrin-linked kinase	0.0007	0.5	0.5
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0007	0.5	0.5
Echinococcus granulosus	activin receptor type	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Brugia malayi	ephrin receptor 1 precursor	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/ROR protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase HCK	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/CSK protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	ephrin receptor	0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0007	0.5	0.5
Leishmania major	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/DDR protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	protein tyrosine kinase	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0007	0.5	0.5
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/Met protein kinase	0.0007	0.5	0.5
Brugia malayi	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0007	0.5	0.5
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trypanosoma brucei	protein kinase, putative	0.0007	0.5	0.5
Plasmodium falciparum	tyrosine kinase-like protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	ankyrin repeat protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase shark	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Plasmodium falciparum	protein kinase, putative	0.0007	0.5	0.5
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0007	0.5	0.5
Brugia malayi	SH2 domain containing protein	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TK family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FAK protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Giardia lamblia	Kinase, NEK	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Brugia malayi	SRC-1	0.0007	0.5	0.5
Trypanosoma brucei	Pseudokinase, putative	0.0007	0.5	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase csk	0.0007	0.5	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0007	0.5	0.5
Plasmodium falciparum	tyrosine kinase-like protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	epidermal growth factor receptor	0.0007	0.5	0.5
Echinococcus granulosus	natriuretic peptide receptor 1	0.0007	0.5	0.5
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	protein kinase atn1, putative	0.0007	0.5	0.5
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0007	0.5	0.5
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0007	0.5	0.5
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	c src tyrosine kinase	0.0007	0.5	0.5
Echinococcus granulosus	protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0007	0.5	0.5
Plasmodium falciparum	protein kinase, putative	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Echinococcus multilocularis	protein tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0007	0.5	0.5
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Loa Loa (eye worm)	TK protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0007	0.5	0.5
Trichomonas vaginalis	CAMK family protein kinase	0.0007	0.5	0.5
Brugia malayi	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0007	0.5	0.5
Echinococcus granulosus	protein tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0007	0.5	0.5
Brugia malayi	Furin-like cysteine rich region family protein	0.0007	0.5	0.5
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0007	0.5	0.5
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0007	0.5	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0007	0.5	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	protein-tyrosine kinase	0.0007	0.5	0.5
Schistosoma mansoni	serine/threonine RGC	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0007	0.5	0.5
Echinococcus multilocularis	insulin receptor	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase, putative	0.0007	0.5	0.5
Onchocerca volvulus		0.0007	0.5	0.5
Entamoeba histolytica	serine/threonine kinase, putative	0.0007	0.5	0.5
Entamoeba histolytica	cysteine surface protein, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	integrin linked protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	hypothetical protein	0.0007	0.5	0.5
Brugia malayi	Tyrosine-protein kinase PR2	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine protein kinase	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Brugia malayi	Protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	SRC-1	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Brugia malayi	Receptor family ligand binding region containing protein	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase shark	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Schistosoma mansoni	hypothetical protein	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Entamoeba histolytica	tyrosin kinase, putative	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Brugia malayi	Guanylyl cyclase protein 23	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/EPH protein kinase	0.0007	0.5	0.5
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0007	0.5	0.5
Entamoeba histolytica	hypothetical protein	0.0007	0.5	0.5
Schistosoma mansoni	protein kinase	0.0007	0.5	0.5
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0007	0.5	0.5
Schistosoma mansoni	tyrosine kinase	0.0007	0.5	0.5
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0007	0.5	0.5
Onchocerca volvulus	Tyrosine kinase homolog	0.0007	0.5	0.5
Entamoeba histolytica	protein kinase domain containing protein	0.0007	0.5	0.5
Entamoeba histolytica	tyrosine kinase, putative	0.0007	0.5	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0007	0.5	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0007	0.5	0.5
Toxoplasma gondii	protein kinase domain-containing protein	0.0007	0.5	0.5
Echinococcus granulosus	receptor type guanylyl cyclase	0.0007	0.5	0.5
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0007	0.5	0.5

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (functional)	= 7.36 uM	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	ChEMBL.	23558238
IC50 (functional)	= 26.28 uM	Cytotoxicity against human K562 cells after 48 hrs by MTT assay	ChEMBL.	23558238

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23	23558238

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2376814

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1761285