Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0085 | 0.0019 |
Echinococcus granulosus | neuroligin | 0.0049 | 0.0562 | 0.0499 |
Leishmania major | arginine N-methyltransferase, type I | 0.0058 | 0.0696 | 0.9519 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0309 | 0.0251 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0399 | 0.0396 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0138 | 0.0079 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0225 | 0.0211 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0049 | 0.0562 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0263 | 0.0252 |
Toxoplasma gondii | bicoid-interacting protein BIN3 | 0.0058 | 0.0696 | 0.0673 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0728 | 0.0666 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0263 | 0.0205 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0562 | 0.057 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0067 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.206 | 0.2164 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0049 | 0.0562 | 0.0499 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.0696 | 0.0641 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0363 | 0.0299 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.1593 | 0.1666 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0049 | 0.0562 | 0.0499 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0263 | 0.931 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0728 | 0.0673 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0728 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0025 | 0.0204 | 0.0138 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0696 | 0.0713 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0049 | 0.0562 | 0.0499 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0283 | 0.0225 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0058 | 0.0696 | 1 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0067 | 0.0043 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0097 | 0.1272 | 0.1326 |
Onchocerca volvulus | 0.0049 | 0.0562 | 0.0367 | |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0097 | 0.1272 | 0.1214 |
Trypanosoma brucei | Protein arginine N-methyltransferase 1 catalytic subunit | 0.0058 | 0.0696 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0067 | 0.011 |
Leishmania major | arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 | 0.0058 | 0.0696 | 0.9519 |
Echinococcus multilocularis | protein arginine N methyltransferase 7 | 0.0058 | 0.0696 | 0.0634 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0049 | 0.0562 | 0.7483 |
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0058 | 0.0696 | 0.5 |
Echinococcus multilocularis | histone arginine methyltransferase CARMER | 0.0649 | 0.9425 | 0.9421 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0097 | 0.1272 | 0.122 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0021 | 0.0148 | 0.0129 |
Brugia malayi | Carboxylesterase family protein | 0.0291 | 0.4142 | 0.4379 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.079 | 0.0735 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0025 | 0.0204 | 0.0145 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.233 | 0.2284 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0283 | 0.0218 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0562 | 0.0506 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0283 | 0.0231 |
Echinococcus granulosus | histone arginine methyltransferase CARMER | 0.0649 | 0.9425 | 0.9421 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0049 | 0.0562 | 0.0499 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0204 | 0.2266 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0309 | 0.0244 |
Echinococcus multilocularis | phd:f box containing protein | 0.0025 | 0.0204 | 0.0138 |
Trichomonas vaginalis | set domain proteins, putative | 0.0237 | 0.3333 | 1 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0067 | 0.2528 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0208 | 0.2909 | 0.3067 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0263 | 0.0008 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.019 | 0.0132 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0094 | 0.122 | 0.1161 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0146 | 0.008 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0085 | 0.0019 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0728 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0067 | 0.0043 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0283 | 0.0225 |
Onchocerca volvulus | 0.003 | 0.0283 | 0.0031 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0434 | 0.0434 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0025 | 0.0204 | 0.2266 |
Brugia malayi | Carboxylesterase family protein | 0.0291 | 0.4142 | 0.4379 |
Onchocerca volvulus | 0.0049 | 0.0562 | 0.0367 | |
Brugia malayi | Protein arginine N-methyltransferase | 0.0058 | 0.0696 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.4142 | 0.4379 |
Onchocerca volvulus | 0.059 | 0.8563 | 1 | |
Loa Loa (eye worm) | protein arginine N-methyltransferase | 0.0058 | 0.0696 | 0.0713 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0204 | 0.0188 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0138 | 0.0118 |
Trypanosoma cruzi | arginine N-methyltransferase, type III | 0.0058 | 0.0696 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0728 | 0.0666 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.1593 | 0.1666 |
Brugia malayi | Carm1-pending protein | 0.0649 | 0.9425 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0291 | 0.4142 | 0.4103 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0728 | 0.0673 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0263 | 0.5 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0298 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0801 | 0.0824 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0025 | 0.0204 | 0.0145 |
Entamoeba histolytica | arginine N-methyltransferase 1, putative | 0.0058 | 0.0696 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.019 | 0.0124 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0085 | 0.0026 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0688 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0728 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0432 | 0.0367 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0291 | 0.4142 | 0.4107 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0204 | 0.0188 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0049 | 0.0562 | 0.7483 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0309 | 0.0244 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0204 | 0.0188 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0204 | 0.2266 |
Trypanosoma cruzi | protein arginine n-methyltransferase 7 | 0.0058 | 0.0696 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0298 | 0.0289 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0963 | 0.0996 |
Echinococcus granulosus | methyltransferase protein 5 | 0.0058 | 0.0696 | 0.0634 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0058 | 0.0696 | 0.0485 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0263 | 0.0198 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0146 | 0.0088 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0291 | 0.4142 | 0.4103 |
Loa Loa (eye worm) | carboxylesterase | 0.0291 | 0.4142 | 0.4379 |
Plasmodium vivax | JmjC domain containing protein | 0.0025 | 0.0204 | 0.7195 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0025 | 0.0204 | 0.0138 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.1593 | 0.1666 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0534 | 0.054 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0263 | 0.021 |
Brugia malayi | jmjC domain containing protein | 0.0154 | 0.2107 | 0.2214 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0562 | 0.057 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0049 | 0.0562 | 0.0506 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0067 | 0.2354 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0146 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0398 | 0.0395 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.0534 | 0.0471 |
Loa Loa (eye worm) | carboxylesterase | 0.0049 | 0.0562 | 0.057 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0204 | 0.0188 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0067 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0876 | 0.0904 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0049 | 0.0562 | 0.7483 |
Schistosoma mansoni | jumonji domain containing protein | 0.0134 | 0.1818 | 0.1769 |
Echinococcus granulosus | acetylcholinesterase | 0.0291 | 0.4142 | 0.4103 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0067 | 0.0116 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0562 | 0.0506 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0049 | 0.0562 | 0.0506 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0688 | 1 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0025 | 0.0204 | 0.0145 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.233 | 0.2284 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0204 | 0.0188 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0025 | 0.0204 | 0.7728 |
Loa Loa (eye worm) | carboxylesterase | 0.0049 | 0.0562 | 0.057 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0686 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0696 | 0.0713 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0067 | 0.0116 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0263 | 1 |
Brugia malayi | hypothetical protein | 0.0151 | 0.206 | 0.2164 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0562 | 0.057 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0298 | 0.0233 |
Schistosoma mansoni | gliotactin | 0.0049 | 0.0562 | 0.0506 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0257 | 0.0245 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0025 | 0.0204 | 0.0138 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0049 | 0.0562 | 0.0506 |
Trypanosoma brucei | protein arginine n-methyltransferase 7 | 0.0058 | 0.0696 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0737 | 0.0675 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0721 | 0.0739 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.019 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0486 | 0.0489 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0534 | 0.0478 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0432 | 0.0367 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0095 | 0.0036 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0058 | 0.0696 | 0.0485 |
Echinococcus granulosus | phd:f box containing protein | 0.0025 | 0.0204 | 0.0138 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0085 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Schistosoma mansoni | acetylcholinesterase | 0.0049 | 0.0562 | 0.0506 |
Brugia malayi | jmjC domain containing protein | 0.0097 | 0.1272 | 0.1326 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0154 | 0.2107 | 0.2054 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.4142 | 0.4379 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0025 | 0.0204 | 0.0138 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0257 | 0.0199 |
Onchocerca volvulus | 0.0151 | 0.206 | 0.2171 | |
Echinococcus granulosus | acetylcholinesterase | 0.0291 | 0.4142 | 0.4103 |
Schistosoma mansoni | protein arginine n-methyltransferase | 0.0649 | 0.9425 | 0.9422 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0049 | 0.0562 | 0.0499 |
Brugia malayi | Carboxylesterase family protein | 0.0049 | 0.0562 | 0.057 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0309 | 0.0251 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.0534 | 0.0471 |
Echinococcus multilocularis | geminin | 0.0169 | 0.233 | 0.2279 |
Toxoplasma gondii | histone arginine methyltransferase PRMT3 | 0.0058 | 0.0696 | 0.0673 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.0058 | 0.0696 | 0.0485 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0728 | 0.0707 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0728 | 1 |
Echinococcus multilocularis | neuroligin | 0.0049 | 0.0562 | 0.0499 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0025 | 0.0204 | 0.0146 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0263 | 0.0252 |
Echinococcus multilocularis | acetylcholinesterase | 0.0291 | 0.4142 | 0.4103 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0263 | 0.0198 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0025 | 0.0204 | 0.0138 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0097 | 0.1272 | 0.122 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0204 | 0.0188 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0029 | 0.0256 | 0.019 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0534 | 0.0478 |
Toxoplasma gondii | histone arginine methyltransferase PRMT4/CARM1 | 0.0649 | 0.9425 | 1 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0058 | 0.0696 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0257 | 0.0245 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0025 | 0.0204 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0263 | 0.0205 |
Entamoeba histolytica | hypothetical protein | 0.0058 | 0.0696 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0737 | 0.0675 |
Onchocerca volvulus | 0.0049 | 0.0562 | 0.0367 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0291 | 0.4142 | 0.4379 |
Echinococcus granulosus | geminin | 0.0169 | 0.233 | 0.2279 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0204 | 0.0188 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0058 | 0.0696 | 1 |
Onchocerca volvulus | 0.0049 | 0.0562 | 0.0367 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0257 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0204 | 0.0188 |
Brugia malayi | Pre-SET motif family protein | 0.0208 | 0.2909 | 0.3067 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0263 | 0.0252 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0067 | 0.0116 |
Onchocerca volvulus | 0.0237 | 0.3333 | 0.3703 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0728 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0204 | 0.0188 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0747 | 0.0692 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0094 | 0.0072 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0363 | 0.0299 |
Schistosoma mansoni | jumonji domain containing protein | 0.0025 | 0.0204 | 0.0145 |
Loa Loa (eye worm) | Carm1-pending protein | 0.0649 | 0.9425 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0067 | 0.0116 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0058 | 0.0696 | 1 |
Echinococcus granulosus | protein arginine N methyltransferase 7 | 0.0058 | 0.0696 | 0.0634 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0025 | 0.0204 | 0.0138 |
Echinococcus multilocularis | acetylcholinesterase | 0.0291 | 0.4142 | 0.4103 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0283 | 0.0273 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0263 | 0.021 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Onchocerca volvulus | 0.0049 | 0.0562 | 0.0367 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0562 | 0.057 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0154 | 0.2107 | 0.2054 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0204 | 0.2157 |
Schistosoma mansoni | phd/f-box containing protein | 0.0025 | 0.0204 | 0.0145 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0283 | 1 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0029 | 0.0256 | 0.019 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (binding) | > 100 uM | Inhibition of MRP1 (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence assay | ChEMBL. | 23726026 |
EC50 (binding) | > 100 uM | Inhibition of BCRP (unknown origin) expressed in MDCK cells assessed as reduction of calcein-AM transport after 30 mins by fluorescence assay | ChEMBL. | 23726026 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.