Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0143 | 0.4068 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0004 | 0.0007 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0004 | 0.0004 |
Brugia malayi | Muscle positioning protein 4 | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.3238 | 0.3238 |
Mycobacterium tuberculosis | Probable reductase | 0.0111 | 0.2732 | 0.6656 |
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Echinococcus multilocularis | notch | 0.0051 | 0.0184 | 0.0339 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0051 | 0.0184 | 0.0339 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0777 | 0.0777 |
Echinococcus granulosus | slit 2 protein | 0.0051 | 0.0184 | 0.0339 |
Echinococcus multilocularis | fibropellin Ia | 0.0051 | 0.0184 | 0.0339 |
Onchocerca volvulus | 0.0108 | 0.2576 | 1 | |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0051 | 0.0184 | 0.0339 |
Echinococcus granulosus | protein jagged 1 | 0.0051 | 0.0184 | 0.0339 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0143 | 0.4068 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0072 | 0.0176 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0777 | 0.0777 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0072 | 0.0072 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0143 | 0.4068 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0111 | 0.2732 | 0.6656 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | peroxidasin | 0.0108 | 0.2576 | 0.2576 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0124 | 0.326 | 0.7978 |
Onchocerca volvulus | Peroxidase homolog | 0.0108 | 0.2576 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.0051 | 0.0184 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.183 | 0.183 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0004 | 0.0007 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0777 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Mycobacterium ulcerans | glutaminase | 0.0282 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0108 | 0.2576 | 0.2576 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0072 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0051 | 0.0184 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0051 | 0.0184 | 0.0339 |
Echinococcus granulosus | neural cadherin | 0.0051 | 0.0184 | 0.0339 |
Echinococcus multilocularis | Mastin | 0.0049 | 0.0077 | 0.0141 |
Onchocerca volvulus | 0.0051 | 0.0184 | 0.0715 | |
Onchocerca volvulus | 0.009 | 0.183 | 0.7104 | |
Onchocerca volvulus | 0.0108 | 0.2576 | 1 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | 0.0051 | 0.0184 | 0.0715 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0777 | 0.0777 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0004 | 0.0004 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0051 | 0.0184 | 0.0715 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0777 | 0.0777 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0777 | 0.0777 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0051 | 0.0184 | 0.0339 |
Onchocerca volvulus | 0.0051 | 0.0184 | 0.0715 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | notch protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | Notch2 | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0111 | 0.2732 | 0.6656 |
Schistosoma mansoni | septate junction protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.009 | 0.183 | 0.183 |
Onchocerca volvulus | 0.0108 | 0.2576 | 1 | |
Echinococcus multilocularis | protein jagged 1 | 0.0051 | 0.0184 | 0.0339 |
Echinococcus granulosus | notch | 0.0051 | 0.0184 | 0.0339 |
Loa Loa (eye worm) | glutaminase | 0.0282 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | Peroxidasin homolog | 0.0108 | 0.2576 | 1 |
Echinococcus granulosus | delta-like protein 1 | 0.0051 | 0.0184 | 0.0339 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0143 | 0.4068 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0108 | 0.2576 | 0.2576 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0143 | 0.4068 | 0.7483 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0108 | 0.2576 | 0.2576 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0051 | 0.0184 | 0.0453 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0072 | 0.0072 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0777 | 0.0777 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0777 | 0.0777 |
Echinococcus granulosus | Mastin | 0.0049 | 0.0077 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | 0.0051 | 0.0184 | 0.0715 | |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.3238 | 0.3238 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0051 | 0.0184 | 0.0715 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0777 | 0.0777 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | Animal haem peroxidase family protein | 0.0108 | 0.2576 | 0.2576 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | Cadherin domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.5437 | 0.5437 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0111 | 0.2732 | 0.6656 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0049 | 0.0077 | 0.0141 |
Schistosoma mansoni | cell polarity protein | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | Cadherin domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0051 | 0.0184 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0049 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus multilocularis | enteropeptidase | 0.0049 | 0.0077 | 0.0141 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0072 | 0.0072 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0072 | 0.0176 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0143 | 0.4068 | 0.4068 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0108 | 0.2576 | 1 |
Echinococcus multilocularis | protein jagged 2 | 0.0051 | 0.0184 | 0.0339 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | peroxidasin | 0.0108 | 0.2576 | 0.2576 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0051 | 0.0184 | 0.0184 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0777 | 0.1429 |
Brugia malayi | notch-like transmembrane receptor | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0124 | 0.326 | 0.3955 |
Echinococcus granulosus | protein jagged 2 | 0.0051 | 0.0184 | 0.0339 |
Brugia malayi | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Schistosoma mansoni | slit | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0108 | 0.2576 | 0.2576 |
Echinococcus granulosus | peroxidasin | 0.0108 | 0.2576 | 0.4739 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.183 | 0.183 |
Echinococcus granulosus | protein jagged 2 | 0.0051 | 0.0184 | 0.0339 |
Echinococcus multilocularis | peroxidasin | 0.0108 | 0.2576 | 0.4739 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0124 | 0.326 | 0.7978 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0143 | 0.4068 | 0.4068 |
Brugia malayi | Animal haem peroxidase family protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Onchocerca volvulus | 0.0051 | 0.0184 | 0.0715 | |
Echinococcus granulosus | protein jagged 1 | 0.0051 | 0.0184 | 0.0339 |
Onchocerca volvulus | 0.0073 | 0.108 | 0.4191 | |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0111 | 0.2732 | 0.6656 |
Brugia malayi | Animal haem peroxidase family protein | 0.0108 | 0.2576 | 0.2576 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0143 | 0.4068 | 1 |
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Trichomonas vaginalis | glutaminase, putative | 0.0282 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0777 | 0.1429 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0124 | 0.326 | 0.7978 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0143 | 0.4068 | 0.5 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0143 | 0.4068 | 0.4068 |
Echinococcus multilocularis | slit 2 protein | 0.0051 | 0.0184 | 0.0339 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0051 | 0.0184 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | Peroxidase homolog | 0.0108 | 0.2576 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0004 | 0.0007 |
Brugia malayi | Delta serrate ligand family protein | 0.0051 | 0.0184 | 0.0184 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0143 | 0.4068 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0051 | 0.0184 | 0.0184 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0111 | 0.2732 | 0.6656 |
Brugia malayi | Animal haem peroxidase family protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0108 | 0.2576 | 0.2576 |
Schistosoma mansoni | glutaminase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0051 | 0.0184 | 0.0339 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0051 | 0.0184 | 0.0184 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0072 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.009 | 0.183 | 0.183 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0072 | 0.0176 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0072 | 0.0132 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.3238 | 0.3238 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0143 | 0.4068 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0072 | 0.0176 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0004 | 0.0007 |
Brugia malayi | Peroxidasin | 0.0108 | 0.2576 | 0.2576 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0072 | 0.0176 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0143 | 0.4068 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0108 | 0.2576 | 0.2576 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0072 | 0.0132 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0051 | 0.0184 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Brugia malayi | Animal haem peroxidase family protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0143 | 0.4068 | 1 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0049 | 0.0077 | 0.0141 |
Echinococcus granulosus | proteasome prosome macropain | 0.0143 | 0.4068 | 0.7483 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | notch | 0.0051 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Onchocerca volvulus | Peroxidasin homolog | 0.0108 | 0.2576 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.2576 | 0.2576 |
Brugia malayi | EGF-like domain containing protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0051 | 0.0184 | 0.0339 |
Brugia malayi | Trypsin family protein | 0.009 | 0.183 | 0.183 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0777 | 0.0777 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0004 | 0.0004 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus granulosus | enteropeptidase | 0.0049 | 0.0077 | 0.0141 |
Loa Loa (eye worm) | glutaminase 2 | 0.0282 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0175 | 0.5437 | 1 |
Echinococcus multilocularis | geminin | 0.0175 | 0.5437 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.5437 | 0.5437 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Echinococcus multilocularis | neural cadherin | 0.0051 | 0.0184 | 0.0339 |
Echinococcus granulosus | fibropellin Ia | 0.0051 | 0.0184 | 0.0339 |
Onchocerca volvulus | Putative cubilin | 0.0051 | 0.0184 | 0.0715 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0143 | 0.4068 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0184 | 0.0184 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0777 | 0.0777 |
Onchocerca volvulus | Slit protein homolog | 0.0051 | 0.0184 | 0.0715 |
Onchocerca volvulus | Dual oxidase homolog | 0.0108 | 0.2576 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | = 13 uM | Cytotoxicity against human HuH7 cells after 2 days by MTS assay | ChEMBL. | 23683596 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.