Detailed information for compound 1766056

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 336.603 | Formula: C15H8Cl3N3
  • H donors: 1 H acceptors: 2 LogP: 5.27 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#Cc1c(NCc2ccccc2)c(Cl)c(c(c1Cl)C#N)Cl
  • InChi: 1S/C15H8Cl3N3/c16-12-10(6-19)13(17)14(18)15(11(12)7-20)21-8-9-4-2-1-3-5-9/h1-5,21H,8H2
  • InChiKey: HHDIWOGDBBTVBZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0011 0.0267
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0021 0.0178
Schistosoma mansoni histone deacetylase 0.0046 0.0041 0.0235
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0009 0.022
Loa Loa (eye worm) hypothetical protein 0.0146 0.0157 0.1354
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0 0.0003
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0019 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0015 0.0805
Schistosoma mansoni inositol monophosphatase 0.0038 0.0032 0.0184
Toxoplasma gondii pantoate-beta-alanine ligase 0.8591 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0007 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.0137 0.0128
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0013 0.0013
Toxoplasma gondii histone deacetylase HDAC1 0.0108 0.0114 0.0113
Echinococcus granulosus Smad4 0.0017 0.0007 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0159 0.0911
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0032 0.0275
Echinococcus granulosus ecdysone induced protein 78C 0.0055 0.0051 0.029
Onchocerca volvulus 0.0036 0.0029 0.127
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0015 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0003 0.0188
Trypanosoma cruzi histone deacetylase 1, putative 0.0046 0.0041 0.2784
Brugia malayi Cathepsin L-like precursor 0.0024 0.0015 0.0128
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0032 0.2019
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0072 0.0413
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Brugia malayi conserved hypotetical protein 0.0026 0.0017 0.0147
Schistosoma mansoni histone deacetylase 4 5 0.0108 0.0114 0.0652
Echinococcus granulosus nibrin 0.0011 0 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0055 0.0051 0.0292
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0017 0.0099
Plasmodium falciparum histone deacetylase 2 0.0108 0.0114 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0055 0.0051 0.0292
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0021 0.0178
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0011 0.0267
Onchocerca volvulus 0.0024 0.0015 0.0659
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0013 0.0075
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0009 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Brugia malayi beta-lactamase 0.0038 0.0032 0.0275
Brugia malayi hypothetical protein 0.1004 0.1158 1
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0029 0.127
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0837
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0055 0.0051 0.0292
Schistosoma mansoni hypothetical protein 0.0146 0.0157 0.0901
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0137 0.0136
Echinococcus multilocularis mitogen activated protein kinase 0.0116 0.0122 0.0239
Brugia malayi nuclear receptor RXR 0.0029 0.0021 0.0178
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Echinococcus multilocularis histone deacetylase 6 0.0108 0.0114 0.0223
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0019 0.0161
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0081
Echinococcus multilocularis expressed conserved protein 0.0106 0.0111 0.0218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0009 0.005
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.002 0.0167
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0008 0.0704
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0015 0.0082
Echinococcus granulosus intermediate filament protein 0.0144 0.0156 0.089
Brugia malayi Steroid receptor seven-up type 2 0.0055 0.0051 0.0437
Echinococcus granulosus sodium:glucose cotransporter 0.0038 0.0032 0.0181
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0018 0.0017
Schistosoma mansoni cpg binding protein 0.0031 0.0024 0.0137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0051 0.0437
Schistosoma mansoni amine GPCR 0.0011 0 0.0002
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0019 0.001 0.0009
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0011 0.0514
Echinococcus granulosus cytoplasmic intermediate filament protein 0.007 0.0068 0.0391
Echinococcus granulosus cathepsin l1 0.0024 0.0015 0.0085
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Leishmania major histone deacetylase, putative 0.0046 0.0041 0.2646
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0019 0.0019
Plasmodium falciparum plasmepsin VII 0.0019 0.001 0.0814
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0032 0.2169
Loa Loa (eye worm) hypothetical protein 0.0067 0.0065 0.0562
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.0017 0.0147
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Leishmania major hypothetical protein, conserved 0.0038 0.0032 0.2022
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0122 0.3216
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0024 0.0015 0.0014
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.0014 0.0003 0.0127
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0017 0.0147
Schistosoma mansoni inositol transporter 0.0038 0.0032 0.0183
Onchocerca volvulus 0.0019 0.001 0.0414
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0011 0 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Schistosoma mansoni nuclear receptor 0.0026 0.0017 0.0099
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0011 0.0088
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0029 0.0755
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0116 0.0122 0.8313
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0 0.0002
Echinococcus granulosus histone deacetylase 0.0108 0.0114 0.065
Brugia malayi follicle stimulating hormone receptor 0.0521 0.0594 0.5133
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0019 0.001 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0032 0.0837
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0015 0.0124
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Brugia malayi BRCA1-associated protein 2 containing protein 0.0014 0.0003 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.013 0.3419
Loa Loa (eye worm) beta-lactamase 0.0038 0.0032 0.0275
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0024 0.0015 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.022
Onchocerca volvulus 0.0036 0.0029 0.127
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0092
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.0017 0.0099
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0178
Plasmodium falciparum histone deacetylase, putative 0.0108 0.0114 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0159 0.0911
Schistosoma mansoni neuropeptide receptor 0.0011 0 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0044 0.0376
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0055 0.0051 0.029
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0009 0.022
Plasmodium vivax aspartyl protease, putative 0.0019 0.001 0.0814
Onchocerca volvulus Huntingtin homolog 0.013 0.0139 0.6137
Schistosoma mansoni cpg binding protein 0.0031 0.0024 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Brugia malayi CHE-14 protein 0.0049 0.0044 0.0376
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0041
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0029 0.0166
Schistosoma mansoni hypothetical protein 0.0011 0 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0072 0.0413
Schistosoma mansoni opsin-like receptor 0.0011 0 0.0002
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0013 0.0694
Schistosoma mansoni opsin-like receptor 0.0011 0 0.0002
Onchocerca volvulus 0.0038 0.0032 0.1408
Entamoeba histolytica histone deacetylase, putative 0.0046 0.0041 0.1073
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0122 0.013 0.0744
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0019 0.0019
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0018 0.0009
Schistosoma mansoni biogenic amine receptor 0.0011 0 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0749 0.086 0.493
Brugia malayi Nuclear hormone receptor-like 1 0.0055 0.0051 0.0437
Echinococcus multilocularis Smad4 0.0017 0.0007 0.0014
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0161
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0051 0.0437
Echinococcus granulosus histone deacetylase 7 0.0108 0.0114 0.065
Schistosoma mansoni thyroid hormone receptor 0.0055 0.0051 0.0292
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0213 0.0236 0.2034
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0019 0.0019
Plasmodium falciparum plasmepsin VI 0.0019 0.001 0.0814
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0022 0.0187
Loa Loa (eye worm) histone deacetylase 0.0108 0.0114 0.0979
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0011 0.0891
Echinococcus multilocularis histone deacetylase 8 0.0046 0.0041 0.008
Trichomonas vaginalis chaperonin, putative 0.0028 0.002 0.0509
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.0121 0.0237
Onchocerca volvulus 0.0036 0.0029 0.127
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Echinococcus multilocularis protein patched 0.0049 0.0044 0.0085
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Schistosoma mansoni smad 0.0017 0.0007 0.0041
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.013 0.0139 0.1197
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Schistosoma mansoni neuropeptide receptor 0.0011 0 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0019 0.1608
Schistosoma mansoni hypothetical protein 0.0011 0 0.0002
Echinococcus multilocularis FTZ F1 alpha 0.0055 0.0051 0.0099
Plasmodium vivax histone deacetylase 1, putative 0.0046 0.0041 0.3583
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0051 0.0099
Trypanosoma brucei unspecified product 0.0015 0.0005 0.0318
Leishmania major T-complex protein 1, beta subunit, putative 0.0028 0.002 0.1153
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0053 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0029 0.0755
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0008 0.007
Schistosoma mansoni lamin 0.0144 0.0156 0.0892
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0015 0.0377
Brugia malayi ecdysteroid receptor 0.0055 0.0051 0.0437
Plasmodium falciparum plasmepsin V 0.0019 0.001 0.0814
Schistosoma mansoni cellular tumor antigen P53 0.0153 0.0166 0.0951
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0013 0.0868
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0055 0.0051 0.0437
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0032 0.0032
Loa Loa (eye worm) intermediate filament protein 0.0144 0.0156 0.1341
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0055 0.0051 0.0437
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0019 0.0491
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0072 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Echinococcus multilocularis histone deacetylase 7 0.0108 0.0114 0.0223
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0019 0.0491
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.001 0.0055
Echinococcus granulosus smad 0.0017 0.0007 0.004
Echinococcus multilocularis ubiquitin specific protease 41 0.0122 0.013 0.0254
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0146 0.0157 0.1354
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.0017 0.0099
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Schistosoma mansoni steroid hormone receptor ad4bp 0.0055 0.0051 0.0292
Entamoeba histolytica cysteine proteinase, putative 0.0036 0.0029 0.0755
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0055 0.0051 0.0099
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0008 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0032 0.0182
Brugia malayi MAP kinase sur-1 0.0116 0.0122 0.1052
Leishmania major cathepsin L-like protease 0.0036 0.0029 0.1804
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0116 0.0122 0.8345
Loa Loa (eye worm) inositol-1 0.0038 0.0032 0.0274
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.011
Echinococcus granulosus survival motor neuron protein 1 0.1004 0.1158 0.6636
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0009 0.0048
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0159 0.0311
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0116 0.0122 0.8345
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0015 0.0124
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.0119 0.0233
Schistosoma mansoni hypothetical protein 0.0749 0.086 0.493
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0015 0.0124
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0213 0.0236 0.2034
Leishmania major histone deacetylase, putative 0.0108 0.0114 0.7726
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0013 0.0335
Echinococcus granulosus microtubule associated protein 2 0.1508 0.1744 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0159 0.0909
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0008 0.007
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0 0.0002
Schistosoma mansoni retinoic acid receptor RXR 0.0055 0.0051 0.0292
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.0121 0.0692
Echinococcus multilocularis mitogen activated protein kinase 3 0.0116 0.0122 0.0239
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0122 0.3216
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Mycobacterium leprae Probable lipase LipE 0.0038 0.0032 0.0032
Brugia malayi cytoplasmic intermediate filament protein 0.0077 0.0077 0.0666
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0019 0.1608
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0164 0.0178 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Brugia malayi aspartic protease BmAsp-1, identical 0.0019 0.001 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0318
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0014 0.0003 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0837
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.013 0.8871
Brugia malayi hypothetical protein 0.0026 0.0017 0.0147
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0159 0.0909
Echinococcus multilocularis histone deacetylase 1 0.0046 0.0041 0.008
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.0481 0.0944
Leishmania major cathepsin L-like protease 0.0036 0.0029 0.1804
Plasmodium falciparum cysteine proteinase falcipain 3 0.0036 0.0029 0.252
Entamoeba histolytica hypothetical protein 0.0115 0.0121 0.319
Onchocerca volvulus 0.0036 0.0029 0.127
Schistosoma mansoni apoferritin-2 0.0026 0.0018 0.0101
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0032 0.0024
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0336 0.0379 1
Schistosoma mansoni amine GPCR 0.0011 0 0.0002
Schistosoma mansoni histamine h1 receptor 0.0011 0 0.0002
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0015 0.1258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0055 0.0051 0.0437
Onchocerca volvulus 0.0026 0.0017 0.0752
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0055 0.0051 0.029
Echinococcus granulosus histone deacetylase 6 0.0122 0.013 0.0741
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.2172
Plasmodium vivax histone deacetylase, putative 0.0108 0.0114 1
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.8591 1 1
Onchocerca volvulus Cathepsin F homolog 0.0036 0.0029 0.127
Schistosoma mansoni hypothetical protein 0.0067 0.0066 0.0378
Schistosoma mansoni hypothetical protein 0.0067 0.0066 0.0378
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0008 0.0016
Echinococcus multilocularis ecdysone induced protein 78C 0.0055 0.0051 0.0099
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0012 0.0001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0128
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0178
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.0136 0.0146 1
Onchocerca volvulus Huntingtin homolog 0.013 0.0139 0.6137
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0018 0.5434
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0051 0.029
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0019 0.001 0.0244
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0016
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0044 0.0085
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0011 0.002
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0122 0.013 0.0742
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0027 0.0019
Toxoplasma gondii aspartyl protease ASP1 0.0019 0.001 0.0009
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0128
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.0014 0.0003 0.0003
Schistosoma mansoni biogenic amine receptor 0.0011 0 0.0002
Schistosoma mansoni coup transcription factor 0.0055 0.0051 0.0292
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0 0.0002
Schistosoma mansoni nuclear receptor 0.0026 0.0017 0.0099
Echinococcus multilocularis survival motor neuron protein 1 0.1004 0.1158 0.2273
Echinococcus multilocularis thyroid hormone receptor alpha 0.0055 0.0051 0.0099
Schistosoma mansoni ferritin 0.0026 0.0018 0.0101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Plasmodium vivax plasmepsin IV, putative 0.0019 0.001 0.0814
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Echinococcus granulosus cathepsin l1 0.0036 0.0029 0.0164
Schistosoma mansoni memapsin-2 (A01 family) 0.0479 0.0545 0.3125
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0116 0.0122 0.8345
Loa Loa (eye worm) hypothetical protein 0.0062 0.006 0.0515
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0055 0.0051 0.0437
Loa Loa (eye worm) histone deacetylase 7A 0.0108 0.0114 0.0979
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0055 0.0051 0.2242
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0122 0.013 0.0254
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.024
Echinococcus multilocularis musashi 0.0144 0.0156 0.0305
Leishmania major DNA polymerase eta, putative 0.0022 0.0013 0.0694
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0015 0.0028
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0122 0.013 0.3419
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0013 0.0073
Toxoplasma gondii histone deacetylase HDAC4 0.0046 0.0041 0.0041
Trichomonas vaginalis BRCA1-associated protein, putative 0.0014 0.0003 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Echinococcus granulosus BRCA1 associated protein 0.0014 0.0003 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0072 0.0413
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0067 0.0066 0.0376
Schistosoma mansoni biogenic amine (5HT) receptor 0.0011 0 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0055 0.0051 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0009 0.022
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0017 0.0099
Schistosoma mansoni sodium/solute symporter 0.0038 0.0032 0.0183
Trichomonas vaginalis ferritin, putative 0.0026 0.0018 0.0454
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Brugia malayi isocitrate dehydrogenase 0.0018 0.0008 0.007
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0036 0.0029 0.252
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0011 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.0029 0.0248
Schistosoma mansoni inositol monophosphatase 0.0038 0.0032 0.0184
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0184 0.0201 0.1738
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0041
Leishmania major DNA polymerase kappa, putative 0.0022 0.0013 0.0694
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Brugia malayi hypothetical protein 0.0029 0.0021 0.0178
Echinococcus multilocularis protein dispatched 1 0.0055 0.0052 0.0101
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0013 0.0013
Onchocerca volvulus 0.0027 0.0019 0.0828
Loa Loa (eye worm) hypothetical protein 0.0067 0.0066 0.0566
Toxoplasma gondii histone deacetylase HDAC2 0.0046 0.0041 0.0041
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0028 0.002 0.0038
Brugia malayi nuclear receptor NHR-88 0.0055 0.0051 0.0437
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0122 0.3216
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0038 0.0032 0.0062
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0046
Trypanosoma brucei histone deacetylase 4 0.0108 0.0114 0.7768
Mycobacterium ulcerans hypothetical protein 0.0027 0.0019 0.0019
Leishmania major histone deacetylase, putative 0.0108 0.0114 0.7726
Echinococcus multilocularis high affinity choline transporter 1 0.0348 0.0393 0.077
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0092
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0019 0.1107
Schistosoma mansoni adenoreceptor 0.0011 0 0.0002
Schistosoma mansoni hypothetical protein 0.0012 0.0001 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Schistosoma mansoni hypothetical protein 0.0205 0.0226 0.1296
Echinococcus granulosus cpg binding protein 0.0031 0.0024 0.0135
Brugia malayi histone deacetylase 3 (HD3) 0.0046 0.0041 0.0352
Onchocerca volvulus 0.0036 0.0029 0.127
Schistosoma mansoni nuclear hormone receptor 0.0055 0.0051 0.0292
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0021 0.004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0015 0.0977
Loa Loa (eye worm) DR-78 0.0026 0.0017 0.0147
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0015 0.0377
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0055 0.0051 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Brugia malayi Histone deacetylase family protein 0.0108 0.0114 0.0979
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0122 0.8345
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0019 0.001 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0179 0.0196 0.516
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0007 0.0041
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0137 0.0136
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0019 0.001 0.0081
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0072 0.062
Brugia malayi Histone deacetylase 1 0.0046 0.0041 0.0352
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Schistosoma mansoni cathepsin D (A01 family) 0.0019 0.001 0.0055
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0018 0.0017
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0019 0.0019
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0122 0.013 0.0744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0055 0.0051 0.0437
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0011 0 0.0002
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.0017 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0044 0.1147
Brugia malayi hypothetical protein 0.0019 0.001 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0318
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0246 0.0274 0.0266
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0009 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0146 1
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0137 0.0783
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0011 0.093
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0011 0.0088
Echinococcus multilocularis ferritin 0.0026 0.0018 0.0034
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0017 0.0752
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0019 0.1107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0122 0.8345
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0055 0.0051 0.0099
Brugia malayi T-complex protein 1, beta subunit 0.0028 0.002 0.0167
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0028 0.002 0.1319
Echinococcus multilocularis cysteine protease 0.0036 0.0029 0.0056
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0122 0.013 0.3419
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0019 0.0019
Echinococcus granulosus ferritin 0.0026 0.0018 0.0099
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0013 0.011
Schistosoma mansoni ferritin 0.0026 0.0018 0.0101
Giardia lamblia Kinase, CMGC MAPK 0.0116 0.0122 0.3216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0021 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Onchocerca volvulus 0.0038 0.0032 0.1402
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Loa Loa (eye worm) histone deacetylase 1 0.0046 0.0041 0.0352
Loa Loa (eye worm) fibroinase 0.0036 0.0029 0.0248
Leishmania major cysteine peptidase A (CPA) 0.0036 0.0029 0.1804
Echinococcus granulosus neuropeptide receptor A26 0.0488 0.0556 0.3185
Schistosoma mansoni patched 1 0.0049 0.0044 0.0251
Trypanosoma cruzi cruzipain precursor, putative 0.0012 0.0001 0.0042
Echinococcus granulosus GPCR family 2 0.0067 0.0066 0.0376
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0015 0.0082
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0032 0.0032
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0164 0.0178 0.017
Echinococcus multilocularis tumor protein p63 0.1047 0.1207 0.237
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0 0.0000046286
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.0017 0.0097
Trypanosoma cruzi histone deacetylase, putative 0.0046 0.0041 0.2784
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0024 0.0015 0.0014
Brugia malayi histone deacetylase 1 (HD1) 0.0046 0.0041 0.0352
Loa Loa (eye worm) hypothetical protein 0.0213 0.0236 0.2034
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.0017 0.0033
Plasmodium vivax aspartyl protease, putative 0.0019 0.001 0.0814
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0019 0.001 0.0081
Plasmodium falciparum T-complex protein 1 subunit beta 0.0028 0.002 0.1698
Echinococcus granulosus high affinity choline transporter 1 0.0348 0.0393 0.2249
Echinococcus multilocularis histone deacetylase 3 0.0046 0.0041 0.008
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Echinococcus multilocularis solute carrier family 5 0.0038 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Schistosoma mansoni RAR-like nuclear receptor 0.0055 0.0051 0.0292
Onchocerca volvulus 0.0026 0.0017 0.0752
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0019 0.0019
Toxoplasma gondii ATPase, AAA family protein 0.0011 0 0.00000017502
Loa Loa (eye worm) T-complex protein 1 0.0028 0.002 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0019 0.0018
Echinococcus granulosus histone deacetylase 1 0.0046 0.0041 0.0233
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0336 0.0379 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0055 0.0051 0.2242
Trypanosoma cruzi cysteine peptidase, putative 0.0036 0.0029 0.1958
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0015 0.0124
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0067 0.0066 0.0129
Onchocerca volvulus 0.0019 0.001 0.0414
Brugia malayi nuclear hormone receptor 0.0026 0.0017 0.0147
Brugia malayi Cathepsin L-like precursor 0.0024 0.0015 0.0128
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0011 0.0267
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0061 0.0349
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0122 0.07
Onchocerca volvulus 0.0038 0.0032 0.1408
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0116 0.0122 0.1052
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0015 0.0977
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.0024
Echinococcus granulosus solute carrier family 5 0.0038 0.0032 0.0181
Schistosoma mansoni hypothetical protein 0.0011 0 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0009 0.022
Brugia malayi hypothetical protein 0.0027 0.0019 0.0158
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0032 0.0032
Schistosoma mansoni opsin-like receptor 0.0011 0 0.0002
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0015 0.0377
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0055 0.0051 0.0437
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0032 0.0024
Brugia malayi cathepsin L-like precursor 0.0024 0.0015 0.0128
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0013 0.0868
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0032 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0072 0.0413
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0008 0.0008
Giardia lamblia TCP-1 chaperonin subunit beta 0.0028 0.002 0.0508
Trypanosoma cruzi histone deacetylase, putative 0.0108 0.0114 0.7768
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0032 0.0024
Schistosoma mansoni neuropeptide receptor 0.0011 0 0.0002
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.002 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0055 0.0051 0.0437
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0 0.0002
Brugia malayi hypothetical protein 0.0017 0.0008 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0015 0.0377
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0072 0.062
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0008 0.0008
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0032 0.0836
Mycobacterium ulcerans lipase LipD 0.0038 0.0032 0.0032
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0125 0.0132 0.9054
Schistosoma mansoni histone deacetylase 1 2 3 0.0046 0.0041 0.0235
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0159 0.137
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.0121 0.0694
Loa Loa (eye worm) hypothetical protein 0.007 0.0068 0.0589
Leishmania major cathepsin L-like protease 0.0136 0.0146 1
Treponema pallidum fructose-bisphosphate aldolase 0.0336 0.0379 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.0137 0.0781
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0051 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0055 0.0051 0.0437
Schistosoma mansoni ferritin 0.0026 0.0018 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0178
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.0137 0.0267
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0009 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0015 0.0128
Schistosoma mansoni high-affinity choline transporter 0.0348 0.0393 0.225
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.024
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0003 0.0241
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0011 0.0267
Trichomonas vaginalis esterase, putative 0.0038 0.0032 0.0837
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0024 0.0015 0.0084
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0055 0.0051 0.0437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Brugia malayi Eukaryotic aspartyl protease family protein 0.0019 0.001 0.0081
Echinococcus multilocularis Niemann Pick C1 protein 0.0162 0.0176 0.0344
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0009 0.022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0055 0.0051 0.0437
Entamoeba histolytica cysteine protease, putative 0.0036 0.0029 0.0755
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0273
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Plasmodium falciparum plasmepsin IV 0.0019 0.001 0.0814
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Schistosoma mansoni DNA ligase IV 0.0011 0 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0521 0.0594 0.5133
Brugia malayi CXXC zinc finger family protein 0.003 0.0022 0.0187
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.013 0.8871
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.0017 0.0033
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0015 0.1258
Echinococcus granulosus neuropeptide s receptor 0.0488 0.0556 0.3185
Schistosoma mansoni ferritin light chain 0.0026 0.0018 0.0101
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0158
Loa Loa (eye worm) Smad1 0.0017 0.0007 0.006
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0032 0.0024
Schistosoma mansoni DNA polymerase eta 0.0022 0.0013 0.0075
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0055 0.0051 0.0292
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0011 0.093
Loa Loa (eye worm) hypothetical protein 0.0153 0.0166 0.143
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.028 0.2417
Brugia malayi tailless protein 0.0026 0.0017 0.0147
Echinococcus multilocularis geminin 0.0749 0.086 0.1688
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0011 1
Brugia malayi hypothetical protein 0.0026 0.0017 0.0147
Leishmania major histone deacetylase, putative 0.0046 0.0041 0.2646
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.0024
Loa Loa (eye worm) cysteine protease 0.0036 0.0029 0.0248
Schistosoma mansoni histone deacetylase hda2 0.0046 0.0041 0.0235
Mycobacterium ulcerans beta-lactamase 0.0038 0.0032 0.0032
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0038 0.0032 0.0181
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Schistosoma mansoni myosin xvIII 0.0011 0 0.0002
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0008 0.0704
Leishmania major cathepsin L-like protease 0.0036 0.0029 0.1804
Loa Loa (eye worm) hypothetical protein 0.0144 0.0156 0.1341
Echinococcus granulosus histone deacetylase 6 0.0108 0.0114 0.065
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.0017 0.0097
Echinococcus multilocularis neuropeptide s receptor 0.0488 0.0556 0.1091
Echinococcus granulosus dna polymerase eta 0.0022 0.0013 0.0073
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Onchocerca volvulus 0.003 0.0022 0.0958
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0032 0.0024
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0024 0.0015 0.0377
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.001 0.0814
Plasmodium falciparum plasmepsin II 0.0019 0.001 0.0814
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0017 0.0097
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0017 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0011 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0032 0.2172
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0013 0.0335
Schistosoma mansoni ap endonuclease 0.002 0.0011 0.006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0013 0.0005
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0028 0.002 0.0111
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0547
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0032 0.0836
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0015 0.1258
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0015 0.0128
Plasmodium falciparum plasmepsin VIII, putative 0.0019 0.001 0.0814
Plasmodium vivax histone deacetylase, putative 0.0046 0.0041 0.3583
Onchocerca volvulus 0.0153 0.0166 0.7334
Schistosoma mansoni Smad4 0.0017 0.0007 0.0041
Loa Loa (eye worm) histone deacetylase 11 0.0046 0.0041 0.0352
Schistosoma mansoni hypothetical protein 0.0011 0 0.0002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0007 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Brugia malayi MH2 domain containing protein 0.0017 0.0007 0.006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Schistosoma mansoni topbp1 0.0011 0 0.0003
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0011 0 0.0002
Trypanosoma brucei unspecified product 0.0015 0.0005 0.0318
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0205 0.0226 0.195
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.0017 0.0147
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.0137 0.0136
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.0146 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.0017 0.0147
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0017 0.0097
Echinococcus multilocularis GPCR, family 2 0.0067 0.0066 0.0129
Plasmodium vivax vivapain-3 0.0018 0.0009 0.0733
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Brugia malayi histone deacetylase 11 0.0046 0.0041 0.0352
Brugia malayi hypothetical protein 0.0029 0.0021 0.0178
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0001 0.0002
Echinococcus granulosus expressed protein 0.0026 0.0018 0.0099
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0055 0.0051 0.0099
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0024 0.0015 0.0084
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Brugia malayi hypothetical protein 0.0011 0 0.0001
Echinococcus granulosus lamin dm0 0.0144 0.0156 0.089
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0021 0.012
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0009 0.057
Echinococcus granulosus geminin 0.0749 0.086 0.4929
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Echinococcus multilocularis BRCA1 associated protein 0.0014 0.0003 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0019 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0159 0.0911
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0019 0.1608
Schistosoma mansoni hypothetical protein 0.0067 0.0066 0.0378
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0009 0.0073
Echinococcus granulosus cysteine protease 0.0018 0.0009 0.0048
Loa Loa (eye worm) hypothetical protein 0.1004 0.1158 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0029 0.0056
Trypanosoma brucei histone deacetylase 2 0.0046 0.0041 0.2784
Schistosoma mansoni brca1-associated protein (brap2) 0.0014 0.0003 0.0018
Brugia malayi nuclear receptor NHR-88 0.0026 0.0017 0.0147
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0007 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0122 0.013 0.3419
Brugia malayi hypothetical protein 0.013 0.0139 0.1197
Trypanosoma cruzi histone deacetylase, putative 0.0108 0.0114 0.7768
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Mycobacterium ulcerans hypothetical protein 0.0038 0.0032 0.0032
Trichomonas vaginalis histone deacetylase, putative 0.0046 0.0041 0.1073
Schistosoma mansoni hypothetical protein 0.0067 0.0066 0.0378
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0164 0.0178 0.0178
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0008 0.0547
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0144 0.0156 0.1341
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0038 0.0032 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Trypanosoma cruzi histone deacetylase, putative 0.0046 0.0041 0.2784
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0003 0.0188
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0006
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0017 0.0033
Loa Loa (eye worm) histone deacetylase 3 0.0046 0.0041 0.0352
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Trypanosoma brucei histone deacetylase 1 0.0046 0.0041 0.2784
Toxoplasma gondii histone deacetylase HDAC5 0.0046 0.0041 0.0041
Entamoeba histolytica hypothetical protein 0.0115 0.0121 0.319
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0081
Toxoplasma gondii t-complex protein beta subunit 0.0028 0.002 0.0019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Schistosoma mansoni cathepsin F (C01 family) 0.0036 0.0029 0.0166
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0019 0.0161
Leishmania major cathepsin L-like protease 0.0036 0.0029 0.1804
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Trypanosoma brucei histone deacetylase, putative 0.0108 0.0114 0.7768
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0092
Schistosoma mansoni smad1 5 8 and 0.0017 0.0007 0.0041
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0032 0.0837
Echinococcus granulosus cathepsin L 0.0018 0.0009 0.0048
Echinococcus multilocularis lamin dm0 0.0144 0.0156 0.0305
Brugia malayi Sodium:solute symporter family protein 0.0038 0.0032 0.0273
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0013 0.0075
Brugia malayi topoisomerase 0.0011 0 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.1508 0.1744 0.3425
Echinococcus granulosus sodium:myo inositol cotransporter 0.0038 0.0032 0.0181
Brugia malayi nuclear receptor RXR 0.0026 0.0017 0.0147
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0116 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0122 0.013 0.1118
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0044 0.0249
Schistosoma mansoni lamin 0.0144 0.0156 0.0892
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0116 0.0122 0.8313
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0007 0.004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0159 0.137
Brugia malayi MH1 domain containing protein 0.0017 0.0007 0.006
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.0017 0.0099
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0009 0.057
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0013 0.0025
Schistosoma mansoni neuropeptide receptor 0.0011 0 0.0002
Echinococcus granulosus dnaJ subfamily B 0.0424 0.0481 0.2757
Echinococcus granulosus expressed conserved protein 0.0106 0.0111 0.0635
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0178
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0009 0.022
Echinococcus granulosus histone deacetylase 6 0.0108 0.0114 0.065
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0013 0.0335
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.028 0.2417
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0055 0.0051 0.0437
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0019 0.1249
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0137 0.0783
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0032 0.2169
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0 0.0000046286
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0032 0.0837
Trypanosoma brucei unspecified product 0.0022 0.0013 0.0868
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0046 0.0041 0.1073
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Loa Loa (eye worm) hypothetical protein 0.0142 0.0152 0.1315
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0032 0.0184
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Brugia malayi Inositol-1 0.0038 0.0032 0.0274
Loa Loa (eye worm) hypothetical protein 0.0076 0.0076 0.0652
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0015 0.0377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Onchocerca volvulus 0.0144 0.0156 0.688
Echinococcus granulosus FTZ F1 alpha 0.0055 0.0051 0.029
Plasmodium vivax vivapain-2 0.0036 0.0029 0.252
Echinococcus granulosus lamin 0.0144 0.0156 0.089
Brugia malayi Histone deacetylase family protein 0.0108 0.0114 0.0979
Echinococcus granulosus replication factor c subunit 1 0.0011 0 0.0001
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0019 0.001 0.0018
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0014 0.0003 0.0072
Onchocerca volvulus 0.0036 0.0029 0.127
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0011 0 0.0002
Loa Loa (eye worm) aspartyl protease 6 0.0019 0.001 0.0081
Echinococcus granulosus Niemann Pick C1 protein 0.0162 0.0176 0.1005
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0013 0.0868
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0018 0.0009
Brugia malayi DKFZp564C0469 protein 0.0011 0 0.0001
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0013 0.0868
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.0017 0.0033
Brugia malayi nuclear receptor NHR-67 0.0026 0.0017 0.0147
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0015 0.0087
Echinococcus multilocularis neuropeptide receptor A26 0.0488 0.0556 0.1091
Plasmodium vivax vivapain-2 0.0036 0.0029 0.252
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0013 0.0868
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Schistosoma mansoni growth hormone secretagogue receptor 0.0011 0 0.0002
Mycobacterium tuberculosis Conserved protein 0.0038 0.0032 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0005 0.0318
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0036 0.0029 0.0248
Onchocerca volvulus 0.0144 0.0156 0.688
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0032 0.2172
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0019 0.0161
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.8591 1 1
Onchocerca volvulus 0.0055 0.0051 0.2242
Brugia malayi Smad1 0.0017 0.0007 0.006
Leishmania major cathepsin L-like protease 0.0036 0.0029 0.1804
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Onchocerca volvulus 0.0036 0.0029 0.127
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Schistosoma mansoni intermediate filament proteins 0.0144 0.0156 0.0892
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Brugia malayi Intermediate filament tail domain containing protein 0.0144 0.0156 0.1341
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0055 0.0051 0.0437
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Brugia malayi hypothetical protein 0.0019 0.001 0.0081
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0011 0.0059
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.002 0.0113
Leishmania major cathepsin L-like protease 0.0136 0.0146 1
Echinococcus granulosus histone deacetylase 8 0.0046 0.0041 0.0233
Brugia malayi nuclear hormone receptor 0.0055 0.0051 0.0437
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0366
Brugia malayi RNA binding protein 0.0073 0.0072 0.062
Loa Loa (eye worm) hypothetical protein 0.0046 0.0041 0.0352
Loa Loa (eye worm) hypothetical protein 0.0059 0.0057 0.0486
Giardia lamblia Hypothetical protein 0.0024 0.0015 0.0377
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0146 1
Brugia malayi hypothetical protein 0.0115 0.0121 0.1043
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0055 0.0051 0.0292
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.0119 0.0681
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0015 0.039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0067 0.0066 0.0376
Loa Loa (eye worm) hypothetical protein 0.013 0.0139 0.1197
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0055 0.0051 0.0099
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0032 0.0836
Onchocerca volvulus 0.0038 0.0032 0.1408
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0013 0.0025
Loa Loa (eye worm) hypothetical protein 0.0348 0.0393 0.3389
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Brugia malayi Latrophilin receptor protein 2 0.0067 0.0066 0.0566
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0019 0.0019
Echinococcus multilocularis dna polymerase eta 0.0022 0.0013 0.0025
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Schistosoma mansoni histone deacetylase 4 5 0.0108 0.0114 0.0652
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.0119 0.3137
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0032 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0011 0.0267
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0009 0.057
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0003 0.0188
Onchocerca volvulus 0.0011 0 0.0006
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0024 0.0015 0.0124
Brugia malayi Pepsin A precursor 0.0019 0.001 0.0081
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.007 0.0068 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0055 0.0051 0.0437
Schistosoma mansoni histone deacetylase 0.0046 0.0041 0.0235
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0032 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0009 0.057
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0184 0.0201 0.1738
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0077 0.0077 0.0666
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0178
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0011 0.0692
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0021 0.0178
Leishmania major hypothetical protein, conserved 0.0027 0.0019 0.1082
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0036 0.0029 0.252
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0011 0 0.0002
Schistosoma mansoni brca1-associated protein (brap2) 0.0014 0.0003 0.0018
Toxoplasma gondii ABC1 family protein 0.0038 0.0032 0.0032
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0122 0.013 0.1118
Schistosoma mansoni alpha-1 adrenergic receptor 0.0011 0 0.0002
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0012 0.0001 0.0006
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0038 0.0032 0.0062
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.0017 0.0097
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0055 0.0051 0.029
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0028 0.002 0.1698
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0015 0.0377
Loa Loa (eye worm) hypothetical protein 0.0049 0.0044 0.0376
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0072 0.062
Onchocerca volvulus Bile acid receptor homolog 0.0055 0.0051 0.2242
Plasmodium falciparum plasmepsin III 0.0019 0.001 0.0814
Giardia lamblia DINP protein human, muc B family 0.0022 0.0013 0.0335
Trypanosoma brucei protein kinase, putative 0.0116 0.0122 0.8345
Echinococcus granulosus tumor protein p63 0.1047 0.1207 0.692
Loa Loa (eye worm) ctsf protein 0.0036 0.0029 0.0248
Brugia malayi Nuclear hormone receptor E75 0.0026 0.0017 0.0147
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0032 0.0024
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0032 0.2796
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.0055 0.0051 0.0437
Entamoeba histolytica hypothetical protein 0.0115 0.0121 0.319
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0008 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Brugia malayi TAR-binding protein 0.0073 0.0072 0.062
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0011 0.0692
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0159 0.0311
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0008 0.0547
Brugia malayi aspartic protease BmAsp-2, identical 0.0019 0.001 0.0081
Brugia malayi steroid hormone receptor 0.0055 0.0051 0.0437
Trichomonas vaginalis brca1-associated protein, putative 0.0014 0.0003 0.0072
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0011 0.001
Brugia malayi Cathepsin L-like precursor 0.0012 0.0001 0.0006
Brugia malayi MH2 domain containing protein 0.0251 0.028 0.2417
Trypanosoma cruzi cysteine peptidase, putative 0.0012 0.0001 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0011 0 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Plasmodium vivax unspecified product 0.0018 0.0009 0.0733
Brugia malayi MH2 domain containing protein 0.0017 0.0007 0.006
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Schistosoma mansoni histone deacetylase hda2 0.0122 0.013 0.0743
Plasmodium vivax unspecified product 0.0012 0.0001 0.0054
Schistosoma mansoni inositol transporter 0.0038 0.0032 0.0183
Echinococcus multilocularis cathepsin L 0.0018 0.0009 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0011 0 0.0002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.024
Schistosoma mansoni neuropeptide F-like receptor 0.0011 0 0.0002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0011 0.0891
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0013 0.011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0011 0.0692
Echinococcus granulosus sodium:glucose cotransporter 2 0.0038 0.0032 0.0181
Trypanosoma brucei histone deacetylase 3 0.0108 0.0114 0.7768
Schistosoma mansoni hypothetical protein 0.0424 0.0481 0.2758
Toxoplasma gondii aspartyl protease ASP3 0.0019 0.001 0.0009
Onchocerca volvulus Cathepsin L homolog 0.0036 0.0029 0.127
Trypanosoma cruzi histone deacetylase 1, putative 0.0046 0.0041 0.2784
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.0017 0.0147
Echinococcus multilocularis histone deacetylase 6 0.0122 0.013 0.0254
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0018 0.0454
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0008 0.0547
Echinococcus multilocularis histone deacetylase 0.0108 0.0114 0.0223
Echinococcus multilocularis cysteine protease 0.0036 0.0029 0.0056
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.0017 0.0147
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0021 0.012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0019 0.1249
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0055 0.0051 0.0437
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0036 0.0029 0.0056
Onchocerca volvulus 0.0205 0.0226 1
Toxoplasma gondii histone deacetylase HDAC3 0.0046 0.0041 0.0041
Brugia malayi ecdysone receptor 0.0026 0.0017 0.0147
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0161
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Schistosoma mansoni microtubule-associated protein tau 0.1508 0.1744 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0107 0.0112 0.7666
Loa Loa (eye worm) hypothetical protein 0.0046 0.0041 0.0352
Plasmodium falciparum plasmepsin IX 0.0019 0.001 0.0814
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0011 0 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.0017 0.0752
Brugia malayi photoreceptor-specific nuclear receptor 0.0055 0.0051 0.0437
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0 0.0000046286
Brugia malayi Papain family cysteine protease containing protein 0.0036 0.0029 0.0248
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0028 0.002 0.0113
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0028 0.002 0.1319
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Plasmodium falciparum plasmepsin X 0.0019 0.001 0.0814
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0014 0.0003 0.0241
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0032 0.0836
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0122 0.013 0.8871
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0001 0.0006
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0011 0 0.0002
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.0017 0.0147
Schistosoma mansoni thyroid hormone receptor 0.0055 0.0051 0.0292
Toxoplasma gondii aspartyl protease 0.0019 0.001 0.0009
Loa Loa (eye worm) RNA binding protein 0.0073 0.0072 0.062
Plasmodium vivax plasmepsin V, putative 0.0019 0.001 0.0814
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0019 0.1249
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0072 0.0413
Brugia malayi beta-lactamase family protein 0.0038 0.0032 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0013 0.0868
Echinococcus granulosus tar DNA binding protein 0.0073 0.0072 0.0411
Schistosoma mansoni neuropeptide f receptor 76f 0.0011 0 0.0002
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0024 0.0015 0.0084
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0055 0.0051 0.0437
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0067 0.0066 0.0566
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0011 0.319
Giardia lamblia Histone deacetylase 0.0046 0.0041 0.1073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0001
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0011 0 0.0002
Entamoeba histolytica hypothetical protein 0.0115 0.0121 0.319
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0019 0.1107
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0015 0.039
Onchocerca volvulus Histone deacetylase 10 homolog 0.0046 0.0041 0.1803
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0009 0.057
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0029 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Schistosoma mansoni survival motor neuron protein 0.0205 0.0226 0.1296
Echinococcus multilocularis cpg binding protein 0.0031 0.0024 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0016
Plasmodium vivax aspartyl proteinase, putative 0.0019 0.001 0.0814
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0009 0.022
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0018 0.0017
Brugia malayi Cathepsin L-like precursor 0.0036 0.0029 0.0248
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0032 0.2169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.0001
Echinococcus granulosus mitogen activated protein kinase 3 0.0116 0.0122 0.0698
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0008 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0055 0.0051 0.0437
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0006
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0028 0.002 0.0509
Schistosoma mansoni hypothetical protein 0.0047 0.0042 0.024
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0015 0.039
Brugia malayi Calcitonin receptor-like protein seb-1 0.0213 0.0236 0.2034
Schistosoma mansoni topbp1 0.0011 0 0.0003
Echinococcus multilocularis smad 0.0017 0.0007 0.0014
Schistosoma mansoni apoferritin-2 0.0026 0.0018 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0036 0.0029 0.0755
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0081
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0 0.0001
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0007 0.0014
Echinococcus multilocularis expressed protein 0.0026 0.0018 0.0034
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0046 0.0041 0.1073
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.438 0.5092 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0336 0.0379 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0067 0.0066 0.0566
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0122 0.013 0.0742
Schistosoma mansoni ferritin 0.0026 0.0018 0.0101
Echinococcus granulosus cathepsin L cysteine proteinase 0.0036 0.0029 0.0164
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0009 0.005
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0038 0.0032 0.0032
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0032 0.0182
Plasmodium falciparum plasmepsin I 0.0019 0.001 0.0814
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.0121 0.0694
Echinococcus granulosus cathepsin l cysteine peptidase 0.0036 0.0029 0.0164
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0122 0.013 0.3419
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0046 0.0041 0.1073
Schistosoma mansoni zinc finger protein 0.0026 0.0017 0.0099
Schistosoma mansoni ferritin light chain 0.0026 0.0018 0.0101
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0032 0.0275
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0055 0.0051 0.0099
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0024 0.0015 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.0146 1
Echinococcus multilocularis lamin 0.0144 0.0156 0.0305
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0055 0.0051 0.0292
Schistosoma mansoni amine GPCR 0.0011 0 0.0002
Schistosoma mansoni amine GPCR 0.0011 0 0.0002
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0122 0.013 0.0254
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0009 0.0733
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0009 0.057
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0013 0.011
Plasmodium vivax vivapain-1 0.0018 0.0009 0.0733
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0019 0.0491
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Brugia malayi GH02984p 0.0348 0.0393 0.3389
Plasmodium vivax aspartyl protease, putative 0.0019 0.001 0.0814
Loa Loa (eye worm) hypothetical protein 0.0055 0.0051 0.0437
Plasmodium vivax histone deacetylase 2, putative 0.0108 0.0114 1
Echinococcus granulosus ubiquitin specific protease 41 0.0122 0.013 0.0742
Toxoplasma gondii exonuclease III APE 0.002 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0113 0.0119 0.1026
Schistosoma mansoni hypothetical protein 0.0115 0.0121 0.0694
Echinococcus granulosus mitogen activated protein kinase 0.0116 0.0122 0.0698
Brugia malayi MH1 domain containing protein 0.0017 0.0007 0.006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0147
Entamoeba histolytica cysteine protease, putative 0.0018 0.0009 0.022
Schistosoma mansoni amine GPCR 0.0011 0 0.0002
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0015 0.0977
Giardia lamblia Fructose-bisphosphate aldolase 0.0336 0.0379 1
Plasmodium falciparum histone deacetylase 1 0.0046 0.0041 0.3583
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0044 0.0249
Brugia malayi intermediate filament protein 0.0144 0.0156 0.1341
Schistosoma mansoni biogenic amine receptor 0.0011 0 0.0002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.0137 0.9324
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0055 0.0051 0.029
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0007 0.004
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0067 0.0066 0.0129
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0122 0.3216
Loa Loa (eye worm) hypothetical protein 0.0011 0 0.0001
Echinococcus granulosus dna polymerase kappa 0.0022 0.0013 0.0073
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0036 0.0029 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0036 0.0029 0.0755
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.0017 0.0097
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0015 0.0124
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0003 0.0188
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0055 0.0051 0.029
Brugia malayi cathepsin F-like cysteine proteinase 0.0012 0.0001 0.0006
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.0119 0.1026
Schistosoma mansoni cathepsin s 0.0012 0.0001 0.0006
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0015 0.0028
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0122 0.013 0.885
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0032 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.0146 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0011 0.0092
Echinococcus granulosus histone deacetylase 3 0.0046 0.0041 0.0233
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0065 0.0562
Schistosoma mansoni cpg binding protein 0.003 0.0022 0.0126
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0161
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0014 0.0003 0.0188
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.0017 0.0147
Toxoplasma gondii cathepsin CPL 0.0036 0.0029 0.0029
Brugia malayi hypothetical protein 0.0011 0 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.0036 0.0029 0.0056
Trypanosoma cruzi histone deacetylase, putative 0.0108 0.0114 0.7768
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0028 0.002 0.0509
Brugia malayi beta-lactamase family protein 0.0038 0.0032 0.0275
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0032 0.0024
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0275
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0 0.0000046286
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0015 0.1258
Echinococcus multilocularis histone deacetylase 6 0.0108 0.0114 0.0223
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0019 0.001 0.0055
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0011 0 0.0002

Activities

Activity type Activity value Assay description Source Reference
IZ (functional) Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 1000 ug/mL after 72 hrs by disk diffusion method ChEMBL. 23489634
IZ (functional) Antibacterial activity against Escherichia coli ATCC 8099 assessed as growth inhibition at 1000 ug/mL after 24 hrs by disk diffusion method ChEMBL. 23489634

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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