Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | peptidyl-prolyl cis-trans isomerase | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | peptidyl prolyl isomerase G | 0.055 | 1 | 1 |
Trypanosoma cruzi | 40 kDa cyclophilin, putative | 0.0329 | 0.5424 | 1 |
Plasmodium vivax | peptidyl-prolyl cis-trans isomerase 11, putative | 0.0066 | 0 | 0.5 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase (cyclophilin- 40), putative | 0.0329 | 0.5424 | 1 |
Schistosoma mansoni | peptidyl-prolyl cis-trans isomerase G ppig | 0.055 | 1 | 1 |
Brugia malayi | cyclophilin-type peptidyl-prolyl cis-trans isomerase-15, Bmcyp-5 | 0.0066 | 0 | 0.5 |
Trichomonas vaginalis | cyclophillin, putative | 0.0329 | 0.5424 | 0.5424 |
Loa Loa (eye worm) | cyclophilin-type peptidyl-prolyl cis-trans isomerase-15 | 0.0066 | 0 | 0.5 |
Brugia malayi | cyclophilin-type peptidyl-prolyl cis-trans isomerase-18, Bmcyp-18 | 0.0066 | 0 | 0.5 |
Schistosoma mansoni | peptidyl-prolyl cis-trans isomerase G ppig | 0.055 | 1 | 1 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0329 | 0.5424 | 1 |
Giardia lamblia | Peptidyl-prolyl cis-trans isomerase B precursor | 0.0066 | 0 | 0.5 |
Loa Loa (eye worm) | CYN-5 protein | 0.0066 | 0 | 0.5 |
Onchocerca volvulus | 0.0066 | 0 | 0.5 | |
Leishmania major | cyclophilin 40 | 0.0329 | 0.5424 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0454 | 0.8002 | 0.8002 |
Trypanosoma cruzi | rotamase, putative | 0.0329 | 0.5424 | 1 |
Brugia malayi | cyclophilin-type peptidyl-prolyl cis-trans isomerase-6, Bmcyp-6 | 0.0066 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0454 | 0.8002 | 0.8002 |
Loa Loa (eye worm) | cyclophilin-type peptidyl-prolyl cis-trans isomerase-18 | 0.0066 | 0 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.0454 | 0.8002 | 0.8002 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0454 | 0.8002 | 0.8002 |
Trichomonas vaginalis | peptidyl-prolyl cis-trans isomerase A, ppia, putative | 0.055 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.