Detailed information for compound 1771612

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 419.519 | Formula: C22H17N3O2S2
  • H donors: 0 H acceptors: 3 LogP: 6.41 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1ccccc1/C=N/c1sc2c(c1c1nc3c(s1)cccc3)CCCC2
  • InChi: 1S/C22H17N3O2S2/c26-25(27)17-10-4-1-7-14(17)13-23-21-20(15-8-2-5-11-18(15)28-21)22-24-16-9-3-6-12-19(16)29-22/h1,3-4,6-7,9-10,12-13H,2,5,8,11H2/b23-13+
  • InChiKey: PFWFTYFJRYYPMG-YDZHTSKRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ap endonuclease 0.0018 0.0135 0.0089
Brugia malayi casein kinase 1, delta 0.0037 0.0621 0.0927
Schistosoma mansoni cpg binding protein 0.0031 0.0477 0.0432
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.3255 0.5
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.2162 0.2438
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0135 0.0135
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0845 0.0802
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0845 0.0802
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0733 0.0733
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0135 0.0198
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.3585 0.5376
Echinococcus multilocularis GPCR, family 2 0.0048 0.0903 0.0903
Schistosoma mansoni acetylcholinesterase 0.0046 0.0845 0.0802
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0107 0.006
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0135 0.0198
Brugia malayi CXXC zinc finger family protein 0.0028 0.0388 0.0578
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0845 0.2459
Schistosoma mansoni protein kinase 0.0037 0.0621 0.0577
Onchocerca volvulus 0.0037 0.0621 0.5094
Trypanosoma cruzi casein kinase, putative 0.0037 0.0621 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0091 0.0044
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0296 0.4344
Schistosoma mansoni hypothetical protein 0.0048 0.0903 0.086
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.7017 1
Loa Loa (eye worm) hypothetical protein 0.0269 0.6666 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0388 0.0578
Loa Loa (eye worm) hypothetical protein 0.0103 0.2344 0.3513
Echinococcus granulosus casein kinase I alpha 0.0037 0.0621 0.0621
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0296 0.4217
Schistosoma mansoni hypothetical protein 0.002 0.0181 0.0135
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0918 0.0918
Trypanosoma cruzi casein kinase, putative 0.0037 0.0621 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0683 0.1021
Schistosoma mansoni hypothetical protein 0.0103 0.2344 0.2308
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0037 0.0621 0.0927
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0845 0.1032
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.1206 0.1206
Toxoplasma gondii casein kinase I 0.0037 0.0621 0.5412
Brugia malayi hypothetical protein 0.0016 0.0072 0.0103
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0918 0.0875
Echinococcus granulosus carboxylesterase 5A 0.0269 0.6666 0.6666
Schistosoma mansoni cpg binding protein 0.0028 0.0388 0.0343
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0845 0.0845
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0094 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0621 0.0577
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.006 0.0219
Onchocerca volvulus 0.0046 0.0845 1
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0181 0.0267
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.1206 0.1206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.006 0.006
Trypanosoma cruzi casein kinase, putative 0.0037 0.0621 1
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0432 0.0432
Plasmodium falciparum phd finger protein, putative 0.003 0.0432 0.6632
Echinococcus granulosus geminin 0.0164 0.3926 0.3926
Loa Loa (eye worm) hypothetical protein 0.0043 0.0777 0.1161
Echinococcus granulosus zinc finger protein 0.0021 0.0196 0.0196
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0845 0.1032
Trichomonas vaginalis CK1 family protein kinase 0.0037 0.0621 0.0706
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0135 0.1538
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0845 0.0845
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0845 0.0845
Brugia malayi Isocitrate dehydrogenase 0.0015 0.006 0.0085
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0683 0.0639
Loa Loa (eye worm) hypothetical protein 0.0048 0.0903 0.1351
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.1252 0.1874
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.1097 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0566 0.0566
Brugia malayi hypothetical protein 0.0046 0.0845 0.1264
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0903 0.0903
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0135 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0918 0.0918
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.2183 0.2183
Schistosoma mansoni methyl-cpg binding protein mbd 0.0016 0.0091 0.0044
Toxoplasma gondii exonuclease III APE 0.0018 0.0135 0.073
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.2183 0.2183
Brugia malayi Carboxylesterase family protein 0.0046 0.0845 0.1264
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.7017 0.8278
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0037 0.0621 0.0927
Echinococcus multilocularis casein kinase I alpha 0.0037 0.0621 0.0621
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0296 0.4344
Schistosoma mansoni hypothetical protein 0.003 0.0432 0.0387
Trichomonas vaginalis CK1 family protein kinase 0.0037 0.0621 0.0706
Onchocerca volvulus Alhambra homolog 0.003 0.0432 0.0961
Schistosoma mansoni ap endonuclease 0.0018 0.0135 0.0089
Echinococcus multilocularis acetylcholinesterase 0.0269 0.6666 0.6666
Loa Loa (eye worm) hypothetical protein 0.0037 0.0628 0.0937
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.006 0.0219
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0135 0.1348
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0271 0.0225
Brugia malayi Carboxylesterase family protein 0.0269 0.6666 1
Schistosoma mansoni gliotactin 0.0046 0.0845 0.0802
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0845 0.0802
Leishmania major hypothetical protein, conserved 0.0024 0.0296 0.4344
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Entamoeba histolytica casein kinase 1, putative 0.0037 0.0621 0.0584
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.3255 1
Schistosoma mansoni hypothetical protein 0.0048 0.0903 0.086
Loa Loa (eye worm) hypothetical protein 0.0051 0.0982 0.1469
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0135 0.0237
Schistosoma mansoni hypothetical protein 0.0397 1 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0296 0.2282
Entamoeba histolytica hypothetical protein 0.0096 0.2162 0.2438
Schistosoma mansoni hypothetical protein 0.0048 0.0903 0.086
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0432 0.3589
Loa Loa (eye worm) hypothetical protein 0.0024 0.0296 0.044
Giardia lamblia Kinase, CK1 Casein kinase 0.0037 0.0621 0.0584
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0269 0.6666 1
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0903 0.1351
Onchocerca volvulus 0.0046 0.0845 1
Brugia malayi Carboxylesterase family protein 0.0046 0.0845 0.1264
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0037 0.0621 0.0927
Schistosoma mansoni hypothetical protein 0.0164 0.3926 0.3897
Giardia lamblia PHD finger protein 15 0.003 0.0432 0.0357
Echinococcus granulosus acetylcholinesterase 0.0269 0.6666 0.6666
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0107 0.0107
Echinococcus multilocularis zinc finger protein 0.0021 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Brugia malayi PHD-finger family protein 0.003 0.0432 0.0644
Echinococcus multilocularis casein kinase I delta 0.0037 0.0621 0.0621
Entamoeba histolytica casein kinase, putative 0.0037 0.0621 0.0584
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.006 0.0013
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0016 0.0091 0.0091
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.006 0.006
Echinococcus multilocularis dnaJ subfamily B 0.0397 1 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0845 0.0802
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0296 0.4344
Loa Loa (eye worm) carboxylesterase 0.0269 0.6666 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0016 0.0091 0.0091
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0135 0.0135
Echinococcus multilocularis cpg binding protein 0.0031 0.0477 0.0477
Plasmodium vivax hypothetical protein, conserved 0.003 0.0432 0.6632
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.006 0.0085
Brugia malayi Carboxylesterase family protein 0.0269 0.6666 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.3585 0.5376
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0566 0.0566
Onchocerca volvulus 0.0046 0.0845 1
Brugia malayi isocitrate dehydrogenase 0.0015 0.006 0.0085
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0594 0.0594
Trypanosoma cruzi casein kinase, putative 0.0037 0.0621 1
Schistosoma mansoni hypothetical protein 0.0048 0.0903 0.086
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0903 0.1351
Loa Loa (eye worm) hypothetical protein 0.0151 0.3585 0.5376
Echinococcus multilocularis geminin 0.0164 0.3926 0.3926
Loa Loa (eye worm) hypothetical protein 0.0039 0.0687 0.1027
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0845 0.2276
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0135 0.1538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0107 0.006
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0903 0.1351
Brugia malayi jmjC domain containing protein 0.0039 0.0683 0.1021
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0903 0.0903
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0918 0.0875
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Echinococcus granulosus acetylcholinesterase 0.0269 0.6666 0.6666
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0683 0.0683
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0845 0.2459
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0432 0.3589
Schistosoma mansoni cpg binding protein 0.0031 0.0477 0.0432
Echinococcus granulosus casein kinase I delta 0.0037 0.0621 0.0621
Brugia malayi Bromodomain containing protein 0.0032 0.0491 0.0733
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0845 0.0845
Echinococcus granulosus peregrin 0.0032 0.0491 0.0491
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0918 0.0918
Brugia malayi casein kinase I 0.0037 0.0621 0.0927
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0036 0.0609 0.9798
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0338 0.8449 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0683 0.0639
Echinococcus multilocularis casein kinase I alpha 0.0037 0.0621 0.0621
Echinococcus multilocularis carboxylesterase 5A 0.0269 0.6666 0.6666
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0135 0.1538
Echinococcus granulosus casein kinase I delta 0.0037 0.0621 0.0621
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0918 0.0918
Loa Loa (eye worm) hypothetical protein 0.003 0.0432 0.0644
Echinococcus multilocularis acetylcholinesterase 0.0269 0.6666 0.6666
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0432 0.0432
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0135 0.1538
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0918 0.0875
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.7017 0.8278
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0432 0.0644
Leishmania major casein kinase, putative 0.0037 0.0621 1
Loa Loa (eye worm) hypothetical protein 0.0068 0.1442 0.2159
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0296 0.4217
Echinococcus multilocularis neuroligin 0.0046 0.0845 0.0845
Onchocerca volvulus 0.0046 0.0845 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0845 0.1264
Echinococcus multilocularis casein kinase I delta 0.0037 0.0621 0.0621
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0037 0.0621 1
Echinococcus multilocularis peregrin 0.0032 0.0491 0.0491
Trypanosoma brucei casein kinase I, isoform 2 0.0037 0.0621 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0918 0.1373
Trypanosoma cruzi casein kinase, putative 0.0037 0.0621 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.006 0.0219
Echinococcus granulosus GPCR family 2 0.0048 0.0903 0.0903
Onchocerca volvulus 0.0036 0.0609 0.484
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.006 0.0219
Trichomonas vaginalis CK1 family protein kinase 0.0037 0.0621 0.0706
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.3255 1
Echinococcus granulosus neuroligin 0.0046 0.0845 0.0845
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.3585 0.5376
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0135 0.1348
Brugia malayi Bromodomain containing protein 0.0037 0.0626 0.0935
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0845 0.0845
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0845 0.0802
Brugia malayi PHD-finger family protein 0.0026 0.033 0.0491
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.006 0.006
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.006 0.006
Brugia malayi Carboxylesterase family protein 0.0046 0.0845 0.1264
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0845 0.2459
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.2344 0.3513
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0903 0.0903
Schistosoma mansoni zinc finger protein 0.0021 0.0196 0.015
Giardia lamblia DNA repair protein RAD52 0.0338 0.8449 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0107 0.0156
Onchocerca volvulus 0.0046 0.0845 1
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0733 0.0733
Schistosoma mansoni hypothetical protein 0.0164 0.3926 0.3897
Brugia malayi Bromodomain containing protein 0.0074 0.1591 0.2383
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.006 0.006
Echinococcus granulosus casein kinase i 0.0037 0.0621 0.0621
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0269 0.6666 0.665
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0183 0.0271
Schistosoma mansoni bromodomain containing protein 0.0063 0.1296 0.1255
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.006 0.006
Brugia malayi jmjC domain containing protein 0.0097 0.2183 0.3272
Brugia malayi Carboxylesterase family protein 0.0046 0.0845 0.1264
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0296 0.4217
Loa Loa (eye worm) carboxylesterase 0.0046 0.0845 0.1264
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.006 0.0219
Echinococcus multilocularis casein kinase I alpha 0.0037 0.0621 0.0621
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0918 0.1373
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0271 0.0271
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0432 0.0387
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0903 0.0903
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.1202 0.116
Loa Loa (eye worm) acetylcholinesterase 1 0.0269 0.6666 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.7017 0.8278
Brugia malayi hypothetical protein 0.0024 0.0296 0.044
Schistosoma mansoni jumonji domain containing protein 0.0077 0.1665 0.1626
Plasmodium vivax casein kinase 1, putative 0.0037 0.0621 1
Echinococcus granulosus casein kinase I alpha 0.0037 0.0621 0.0621
Plasmodium falciparum casein kinase 1 0.0037 0.0621 1
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0107 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.7017 1
Echinococcus granulosus cpg binding protein 0.0031 0.0477 0.0477
Loa Loa (eye worm) carboxylesterase 0.0046 0.0845 0.1264
Echinococcus multilocularis casein kinase i 0.0037 0.0621 0.0621
Echinococcus granulosus casein kinase I alpha 0.0037 0.0621 0.0621
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0271 0.0271
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0845 0.0845

Activities

Activity type Activity value Assay description Source Reference
CC50 (ADMET) = 369 ug ml-1 Cytotoxicity against human HeLa cells after 72 hrs by MTT assay ChEMBL. 23920438

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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