TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 472.575 | Formula: C29H32N2O4
H donors: 1 H acceptors: 2 LogP: 5 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: COc1cc(CNC(=O)C2(CCN(C2=O)[C@@H](c2ccccc2)C)Cc2ccccc2)cc(c1)OC
InChi: 1S/C29H32N2O4/c1-21(24-12-8-5-9-13-24)31-15-14-29(28(31)33,19-22-10-6-4-7-11-22)27(32)30-20-23-16-25(34-2)18-26(17-23)35-3/h4-13,16-18,21H,14-15,19-20H2,1-3H3,(H,30,32)/t21-,29?/m1/s1
InChiKey: QWEXCOVACKGPPD-QYWNIODHSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	nuclear receptor subfamily 3, group C, member 2	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/ALK protein kinase	0.0886	0.3955	0.3955
Plasmodium vivax	protein kinase, putative	0.0886	0.3955	1
Leishmania major	hypothetical protein, conserved	0.0886	0.3955	1
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.003	0.0034	0.0006
Brugia malayi	cytokine inducible SH2-containing protein 5	0.132	0.594	0.594
Echinococcus granulosus	tyrosine kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	receptor type guanylyl cyclase	0.0886	0.3955	0.3955
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	serine/threonine RGC	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.132	0.594	0.594
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0886	0.3955	0.3955
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.2206	1	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0075	0.0237	0.043
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Onchocerca volvulus		0.132	0.594	0.594
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	tensin-related	0.132	0.594	0.594
Brugia malayi	Receptor family ligand binding region containing protein	0.0886	0.3955	0.3955
Schistosoma mansoni	vav2	0.132	0.594	0.594
Echinococcus multilocularis	tensin	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Echinococcus granulosus	tyrosine protein kinase Blk	0.2206	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0886	0.3955	0.3955
Mycobacterium tuberculosis	Probable lipase LipD	0.0075	0.0237	0.083
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trypanosoma brucei	protein kinase, putative	0.0886	0.3955	1
Schistosoma mansoni	adapter molecule crk	0.132	0.594	0.594
Entamoeba histolytica	receptor protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	SH2 motif	0.132	0.594	0.594
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0237	0.0525
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Echinococcus granulosus	natriuretic peptide receptor 1	0.0886	0.3955	0.3955
Mycobacterium tuberculosis	Probable dehydrogenase	0.0087	0.0295	0.1117
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Plasmodium falciparum	thioredoxin reductase	0.0038	0.0071	0.01
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.007	0.0215	0.0215
Echinococcus granulosus	tyrosine protein kinase	0.0886	0.3955	0.3955
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Brugia malayi	hypothetical protein	0.0886	0.3955	0.3955
Schistosoma mansoni	serine/threonine protein kinase	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Schistosoma mansoni	tensin-related	0.132	0.594	0.594
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/FAK protein kinase	0.0886	0.3955	0.3955
Brugia malayi	Muscleblind-like protein	0.0146	0.0566	0.0566
Loa Loa (eye worm)	TK/ACK protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.132	0.594	0.594
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.132	0.594	0.594
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.2206	1	1
Plasmodium falciparum	protein kinase, putative	0.0886	0.3955	1
Echinococcus granulosus	activin receptor type	0.0886	0.3955	0.3955
Echinococcus multilocularis	growth factor receptor bound protein 2	0.132	0.594	0.594
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0886	0.3955	0.3955
Brugia malayi	Furin-like cysteine rich region family protein	0.0886	0.3955	0.3955
Schistosoma mansoni	tyrosine protein kinase	0.0886	0.3955	0.3955
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0237	0.0525
Brugia malayi	beta-lactamase	0.0075	0.0237	0.0237
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Trypanosoma cruzi	hypothetical protein, conserved	0.0075	0.0237	0.043
Giardia lamblia	Kinase, NEK	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	shc transforming protein	0.132	0.594	0.594
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.2206	1	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Brugia malayi	Variant SH3 domain containing protein	0.132	0.594	0.594
Brugia malayi	tRNA modification GTPase TrmE family protein	0.132	0.594	0.594
Echinococcus granulosus	tyrosine protein kinase Srms	0.2206	1	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	CAMK family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0075	0.0237	0.083
Giardia lamblia	Kinase	0.0886	0.3955	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Leishmania major	ATP-dependent phosphofructokinase	0.011	0.0399	0.0846
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Echinococcus granulosus	suppressor of cytokine signaling 6	0.132	0.594	0.594
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.132	0.594	0.594
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2206	1	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.2206	1	1
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0566	0.0566
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.007	0.0215	0.0215
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	expressed conserved protein	0.132	0.594	0.594
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.132	0.594	0.594
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0087	0.0295	0.1117
Loa Loa (eye worm)	6-phosphofructokinase	0.011	0.0399	0.0399
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/ABL protein kinase	0.2206	1	1
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Mycobacterium tuberculosis	Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase)	0.011	0.0399	0.1634
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Blk	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.132	0.594	0.594
Echinococcus granulosus	muscleblind protein	0.0146	0.0566	0.0566
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Brugia malayi	SRC-1	0.2206	1	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.0761	0.1859
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.007	0.0215	0.0372
Echinococcus multilocularis	activated cdc42 kinase 1	0.0886	0.3955	0.3955
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Brugia malayi	hypothetical protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Brugia malayi	6-phosphofructokinase	0.011	0.0399	0.0399
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Brugia malayi	Tensin	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trypanosoma brucei	hypothetical protein, conserved	0.0075	0.0237	0.043
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0886	0.3955	1
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.2206	1	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	serine/threonine protein kinase	0.0886	0.3955	0.3955
Onchocerca volvulus		0.003	0.0034	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Mycobacterium leprae	PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)	0.011	0.0399	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tensin	0.132	0.594	0.594
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0886	0.3955	0.3955
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Plasmodium vivax	thioredoxin reductase, putative	0.0038	0.0071	0.01
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0886	0.3955	1
Schistosoma mansoni	ephrin receptor	0.0886	0.3955	0.3955
Plasmodium falciparum	protein kinase, putative	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0886	0.3955	0.3955
Echinococcus multilocularis	transcription factor Dp 1	0.004	0.008	0.008
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Echinococcus multilocularis	integrin linked protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.2206	1	1
Loa Loa (eye worm)	TK protein kinase	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Brugia malayi	Protein kinase domain containing protein	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Mycobacterium tuberculosis	Conserved protein	0.0075	0.0237	0.083
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Onchocerca volvulus		0.2206	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2206	1	1
Onchocerca volvulus		0.024	0.0994	0.0994
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus granulosus	SHC transforming protein 3	0.132	0.594	0.594
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	protein tyrosine kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	ankyrin repeat protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Brugia malayi	Variant SH3 domain containing protein	0.132	0.594	0.594
Mycobacterium tuberculosis	Conserved protein	0.0075	0.0237	0.083
Onchocerca volvulus		0.132	0.594	0.594
Trypanosoma cruzi	ATP-dependent 6-phosphofructokinase, glycosomal	0.011	0.0399	0.0846
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Brugia malayi	Guanylyl cyclase protein 23	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Plasmodium vivax	SET domain protein, putative	0.003	0.0034	0.0006
Loa Loa (eye worm)	hypothetical protein	0.003	0.0034	0.0034
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine kinase	0.2206	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2206	1	1
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0097	0.034	0.1339
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Brugia malayi	Tyrosine-protein kinase PR2	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Leishmania major	protein kinase, putative	0.0886	0.3955	1
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0886	0.3955	1
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Treponema pallidum	diphosphate--fructose-6-phosphate 1-phosphotransferase	0.011	0.0399	1
Trichomonas vaginalis	protein kinase atn1, putative	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Plasmodium vivax	glutathione reductase, putative	0.0038	0.0071	0.01
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	tyrosin kinase, putative	0.0886	0.3955	0.3936
Mycobacterium tuberculosis	Probable lipase LipE	0.0075	0.0237	0.083
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.003	0.0031	0.5
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.2206	1	1
Brugia malayi	Thioredoxin reductase	0.0038	0.0071	0.0071
Echinococcus multilocularis	SHC transforming protein 3	0.132	0.594	0.594
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Schistosoma mansoni	GTPase activating protein	0.132	0.594	0.594
Toxoplasma gondii	protein kinase domain-containing protein	0.0886	0.3955	1
Echinococcus granulosus	tyrosine kinase	0.2206	1	1
Echinococcus granulosus	insulin receptor	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/Met protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.0399	0.0938
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.2206	1	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	SH2 domain containing protein 7	0.132	0.594	0.594
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Schistosoma mansoni	6-phosphofructokinase	0.011	0.0399	0.0399
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0886	0.3955	0.3955
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0215	0.0372
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Echinococcus multilocularis	tensin	0.132	0.594	0.594
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Toxoplasma gondii	ABC1 family protein	0.0075	0.0237	0.0525
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0075	0.0237	0.0237
Brugia malayi	Tyrosine-protein kinase abl-1	0.2206	1	1
Giardia lamblia	Protein 21.1	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.0399	0.0938
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	SH2 motif	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2206	1	1
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0886	0.3955	1
Trichomonas vaginalis	esterase, putative	0.0075	0.0237	0.0525
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	muscleblind protein 1	0.0146	0.0566	0.0566
Echinococcus multilocularis	FL cytokine receptor	0.0886	0.3955	0.3955
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0886	0.3955	0.3955
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Plasmodium falciparum	protein kinase, putative	0.0886	0.3955	1
Echinococcus multilocularis	SH2 motif	0.132	0.594	0.594
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0886	0.3955	0.3955
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Giardia lamblia	Kinase, NEK	0.0886	0.3955	1
Trichomonas vaginalis	penicillin-binding protein, putative	0.0075	0.0237	0.0525
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Protein kinase domain containing protein	0.2206	1	1
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.2206	1	1
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0886	0.3955	0.3955
Schistosoma mansoni	signal transduction protein lnk-related	0.132	0.594	0.594
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0886	0.3955	0.3955
Brugia malayi	beta-lactamase family protein	0.0075	0.0237	0.0237
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	phosphofructokinase	0.011	0.0399	0.0399
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0211	0.086	0.086
Loa Loa (eye worm)	SH2 domain-containing protein	0.132	0.594	0.594
Echinococcus granulosus	NCK adaptor protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.132	0.594	0.594
Chlamydia trachomatis	fructose-6-phosphate phosphotransferase	0.003	0.0031	0.5
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Onchocerca volvulus		0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	SH2A	0.132	0.594	0.594
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0886	0.3955	0.3955
Echinococcus multilocularis	epidermal growth factor receptor	0.0886	0.3955	0.3955
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.0399	0.0938
Onchocerca volvulus		0.2206	1	1
Echinococcus granulosus	protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0189	0.0761	0.1859
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0886	0.3955	0.3955
Brugia malayi	glutathione reductase	0.0038	0.0071	0.0071
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	SH2 domain containing protein	0.132	0.594	0.5928
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.0399	0.0369
Echinococcus multilocularis	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Mycobacterium tuberculosis	Conserved protein	0.0075	0.0237	0.083
Schistosoma mansoni	ephrin receptor	0.0886	0.3955	0.3955
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0273	0.1147	0.1147
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.132	0.594	0.594
Brugia malayi	6-phosphofructokinase	0.011	0.0399	0.0399
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	TK family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.132	0.594	0.594
Loa Loa (eye worm)	6-phosphofructokinase	0.011	0.0399	0.0399
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0034	0.0034
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	NCK adaptor protein	0.132	0.594	0.594
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Brugia malayi	Sex muscle abnormal protein 5	0.132	0.594	0.594
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0087	0.0295	0.1117
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.132	0.594	0.594
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Mycobacterium ulcerans	6-phosphofructokinase	0.011	0.0399	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.2206	1	1
Schistosoma mansoni	serine/threonine protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosin kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	tensin	0.132	0.594	0.594
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.132	0.594	0.594
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Entamoeba histolytica	ankyrin repeat protein	0.0886	0.3955	0.3936
Onchocerca volvulus		0.132	0.594	0.594
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	heat shock protein 70	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.132	0.594	0.594
Onchocerca volvulus	Glucosylceramidase homolog	0.0179	0.0716	0.0716
Echinococcus granulosus	ephrin type A receptor 4 A	0.0886	0.3955	0.3955
Schistosoma mansoni	hypothetical protein	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0075	0.0237	0.083
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0087	0.0295	0.1117
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0029	0.0028	0.0028
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.007	0.0215	0.0184
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0886	0.3955	1
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0034	0.0034
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase csk	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Srms	0.2206	1	1
Onchocerca volvulus		0.132	0.594	0.594
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0273	0.1147	0.1147
Loa Loa (eye worm)	TK/DDR protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0039	0.0073	0.0073
Schistosoma mansoni	nck2/grb4	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Loa Loa (eye worm)	TK/CSK protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	tyrosine protein kinase ABL1	0.2206	1	1
Echinococcus multilocularis	activin receptor type	0.0886	0.3955	0.3955
Plasmodium falciparum	tyrosine kinase-like protein	0.0886	0.3955	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.132	0.594	0.5928
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.003	0.0034	0.0034
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	histone lysine methyltransferase setb	0.003	0.0034	0.0034
Onchocerca volvulus		0.0886	0.3955	0.3955
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0075	0.0237	0.083
Trichomonas vaginalis	AGC family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Onchocerca volvulus		0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.2206	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Schistosoma mansoni	tensin	0.132	0.594	0.594
Echinococcus granulosus	tyrosine protein kinase pr2	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0886	0.3955	0.3955
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Loa Loa (eye worm)	SH2 domain-containing protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Plasmodium falciparum	glutathione reductase	0.0038	0.0071	0.01
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0566	0.0566
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Echinococcus granulosus	suppressor of cytokine signaling 7	0.132	0.594	0.594
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	STAT protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Echinococcus multilocularis		0.132	0.594	0.594
Entamoeba histolytica	protein kinase, putative	0.132	0.594	0.5928
Echinococcus multilocularis	tyrosine protein kinase shark	0.2206	1	1
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.003	0.0034	0.0034
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.2206	1	1
Loa Loa (eye worm)	glutathione reductase	0.0038	0.0071	0.0071
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.0399	0.0369
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.2206	1	1
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.007	0.0215	0.0215
Loa Loa (eye worm)	TK/RYK protein kinase	0.0886	0.3955	0.3955
Brugia malayi	hypothetical protein	0.132	0.594	0.594
Echinococcus granulosus	SH2 domain containing adapter protein F	0.132	0.594	0.594
Echinococcus multilocularis	c src tyrosine kinase	0.2206	1	1
Schistosoma mansoni	hypothetical protein	0.0886	0.3955	0.3955
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Mycobacterium tuberculosis	Probable reductase	0.0087	0.0295	0.1117
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2206	1	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Trypanosoma cruzi	protein kinase, putative	0.0886	0.3955	1
Brugia malayi	beta-lactamase family protein	0.0075	0.0237	0.0237
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Brugia malayi	Protein kinase domain containing protein	0.2206	1	1
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.132	0.594	0.594
Echinococcus granulosus	N chimaerin	0.132	0.594	0.594
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Mycobacterium tuberculosis	Probable hydrolase	0.0075	0.0237	0.083
Loa Loa (eye worm)	TK/INSR protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein, conserved	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	epidermal growth factor receptor	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Brugia malayi	protein-tyrosine kinase	0.2206	1	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0886	0.3955	0.3955
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0215	0.0372
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0477	0.2082	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Toxoplasma gondii	STE kinase	0.0886	0.3955	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.2206	1	1
Trichomonas vaginalis	STE family protein kinase	0.0886	0.3955	1
Brugia malayi	STAT protein, DNA binding domain containing protein	0.132	0.594	0.594
Loa Loa (eye worm)	TK/EPH protein kinase	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Schistosoma mansoni	tensin	0.132	0.594	0.594
Echinococcus granulosus	signal transduction protein lnk realted	0.132	0.594	0.594
Schistosoma mansoni	growth factor receptor-bound protein	0.132	0.594	0.594
Toxoplasma gondii	thioredoxin reductase	0.0038	0.0071	0.01
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus granulosus	tyrosine protein kinase Fyn	0.2206	1	1
Brugia malayi	hypothetical protein	0.2206	1	1
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	epidermal growth factor receptor	0.0886	0.3955	0.3955
Schistosoma mansoni	6-phosphofructokinase	0.011	0.0399	0.0399
Echinococcus multilocularis	tyrosine protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Entamoeba histolytica	receptor protein kinase, putative	0.0886	0.3955	0.3936
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0034	0.0034
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine kinase	0.2206	1	1
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	penicillin-binding protein, putative	0.0075	0.0237	0.0525
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0075	0.0237	0.0237
Brugia malayi	integrin-linked kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase HCK	0.0886	0.3955	0.3955
Toxoplasma gondii	protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0886	0.3955	1
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0886	0.3955	0.3955
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Entamoeba histolytica	hypothetical protein	0.0886	0.3955	0.3936
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	D-aminoacylase, putative	0.0075	0.0237	0.0525
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0097	0.034	0.1339
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0886	0.3955	1
Trichomonas vaginalis	conserved hypothetical protein	0.0886	0.3955	1
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Onchocerca volvulus		0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Variant SH3 domain containing protein	0.132	0.594	0.594
Brugia malayi	SH2 domain containing protein	0.2206	1	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.132	0.594	0.594
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine protein kinase Src64B	0.2206	1	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus multilocularis	protein tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	thioredoxin glutathione reductase	0.0039	0.0073	0.0073
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0886	0.3955	0.3955
Brugia malayi	ephrin receptor 1 precursor	0.0886	0.3955	0.3955
Schistosoma mansoni	protein tyrosine kinase	0.0886	0.3955	0.3955
Schistosoma mansoni	growth factor receptor-bound protein	0.132	0.594	0.594
Entamoeba histolytica	phosphofructokinase, putative	0.011	0.0399	0.0369
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.2206	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	serine/threonine protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.2206	1	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	set domain proteins, putative	0.024	0.0994	0.2453
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0087	0.0295	0.3575
Brugia malayi	Raf kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	glucosylceramidase, putative	0.0273	0.1147	0.2843
Loa Loa (eye worm)	hypothetical protein	0.2206	1	1
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	integrin linked protein kinase	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.132	0.594	0.594
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0886	0.3955	0.3955
Echinococcus granulosus	beta LACTamase domain containing family member	0.0075	0.0237	0.0237
Onchocerca volvulus		0.2206	1	1
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.007	0.0215	0.0215
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.007	0.0215	0.0215
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.2206	1	1
Entamoeba histolytica	protein kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	cysteine surface protein, putative	0.0886	0.3955	0.3936
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0886	0.3955	0.3955
Echinococcus granulosus	6 phosphofructokinase	0.011	0.0399	0.0399
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0886	0.3955	0.3955
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0075	0.0237	0.0237
Echinococcus granulosus	activated cdc42 kinase 1	0.0886	0.3955	0.3955
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.132	0.594	0.594
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0097	0.034	0.6336
Onchocerca volvulus		0.0886	0.3955	0.3955
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0886	0.3955	0.3955
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	Variant SH3 domain containing protein	0.132	0.594	0.594
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.132	0.594	0.594
Echinococcus granulosus	kinase suppressor of Ras 1	0.0886	0.3955	0.3955
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0886	0.3955	1
Leishmania major	hypothetical protein, conserved	0.0075	0.0237	0.043
Loa Loa (eye worm)	thioredoxin reductase	0.0038	0.0071	0.0071
Echinococcus granulosus	epidermal growth factor receptor	0.0886	0.3955	0.3955
Brugia malayi	phosphofructokinase	0.011	0.0399	0.0399
Brugia malayi	Protein kinase domain containing protein	0.2206	1	1
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0075	0.0237	0.0237
Brugia malayi	C-terminal src kinase protein 1	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Leishmania major	protein kinase, putative	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.2206	1	1
Echinococcus multilocularis	tyrosine protein kinase Abl	0.2206	1	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0097	0.034	0.1339
Plasmodium falciparum	tyrosine kinase-like protein	0.0886	0.3955	1
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	activated cdc42 kinase 1	0.0886	0.3955	0.3955
Echinococcus multilocularis	SH2 motif	0.132	0.594	0.594
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0886	0.3955	1
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0886	0.3955	1
Onchocerca volvulus		0.132	0.594	0.594
Entamoeba histolytica	serine/threonine kinase, putative	0.0886	0.3955	0.3936
Mycobacterium tuberculosis	Probable esterase LipL	0.0075	0.0237	0.083
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.132	0.594	0.594
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.132	0.594	0.594
Onchocerca volvulus	Tyrosine kinase homolog	0.0886	0.3955	0.3955
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0886	0.3955	1
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0886	0.3955	0.3955
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.003	0.0034	0.0034
Plasmodium vivax	hypothetical protein, conserved	0.0075	0.0237	0.0525
Trichomonas vaginalis	phosphofructokinase, putative	0.011	0.0399	0.0938
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0886	0.3955	0.3955
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0886	0.3955	0.3955
Echinococcus multilocularis	SH2 motif	0.132	0.594	0.594
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0886	0.3955	0.3955
Trypanosoma brucei	ATP-dependent 6-phosphofructokinase, glycosomal	0.011	0.0399	0.0846
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0087	0.0295	0.1117
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Loa Loa (eye worm)	beta-lactamase	0.0075	0.0237	0.0237
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.132	0.594	0.594
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	SH2 domain containing protein 7	0.132	0.594	0.594
Entamoeba histolytica	tyrosine kinase, putative	0.0886	0.3955	0.3936
Entamoeba histolytica	tyrosin kinase, putative	0.0886	0.3955	0.3936
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.2206	1	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Loa Loa (eye worm)	TK/FER protein kinase	0.2206	1	1
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.007	0.0215	0.0372
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0886	0.3955	0.3955
Onchocerca volvulus		0.2206	1	1
Loa Loa (eye worm)	SH2 domain-containing protein	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.2206	1	1
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0075	0.0237	0.0237
Onchocerca volvulus		0.0075	0.0237	0.0237
Schistosoma mansoni	suppressor of cytokine signaling	0.132	0.594	0.594
Echinococcus granulosus	c src tyrosine kinase	0.2206	1	1
Echinococcus multilocularis	tyrosine kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0886	0.3955	1
Echinococcus multilocularis	transfer RNA-Thr	0.0886	0.3955	0.3955
Echinococcus granulosus	growth factor receptor bound protein 2	0.132	0.594	0.594
Loa Loa (eye worm)	TK/FER protein kinase	0.0886	0.3955	0.3955
Echinococcus granulosus	hypothetical protein	0.132	0.594	0.594
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0886	0.3955	0.3936
Echinococcus granulosus	transcription factor Dp 1	0.004	0.008	0.008
Brugia malayi	SH2 domain containing protein	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	glucosylceramidase, putative	0.0179	0.0716	0.1746
Echinococcus multilocularis	N chimaerin	0.132	0.594	0.594
Loa Loa (eye worm)	hypothetical protein	0.132	0.594	0.594
Entamoeba histolytica	tyrosin kinase, putative	0.0886	0.3955	0.3936
Schistosoma mansoni	serine/threonine protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	signal transduction protein lnk realted	0.132	0.594	0.594
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0886	0.3955	1
Loa Loa (eye worm)	SRC-1	0.2206	1	1
Schistosoma mansoni	hypothetical protein	0.132	0.594	0.594
Onchocerca volvulus		0.2206	1	1
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.132	0.594	0.594
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0886	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.0886	0.3955	0.3955
Echinococcus multilocularis	protein kinase	0.0886	0.3955	0.3955
Brugia malayi	Pre-SET motif family protein	0.0211	0.086	0.086
Echinococcus multilocularis	insulin receptor	0.0886	0.3955	0.3955
Trypanosoma cruzi	protein kinase, putative	0.0886	0.3955	1
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Brugia malayi	RhoGAP domain containing protein	0.132	0.594	0.594
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Loa Loa (eye worm)	TK protein kinase	0.0886	0.3955	0.3955
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0075	0.0237	0.0237
Echinococcus granulosus	raf serine:threonine protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Schistosoma mansoni	protein kinase	0.0886	0.3955	0.3955
Trichomonas vaginalis	TKL family protein kinase	0.0886	0.3955	1
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0886	0.3955	0.3936
Entamoeba histolytica	protein kinase domain containing protein	0.0886	0.3955	0.3936
Schistosoma mansoni	suppressor of cytokine signaling	0.132	0.594	0.594
Schistosoma mansoni	tyrosine kinase	0.0886	0.3955	0.3955
Brugia malayi	SH2 domain containing protein	0.2206	1	1
Echinococcus multilocularis	6 phosphofructokinase	0.011	0.0399	0.0399
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0886	0.3955	0.3955
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0886	0.3955	0.3955
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0886	0.3955	0.3955
Echinococcus multilocularis	muscleblind protein	0.0146	0.0566	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0075	0.0237	0.0237
Brugia malayi	Protein kinase domain containing protein	0.0886	0.3955	0.3955
Onchocerca volvulus		0.0075	0.0237	0.0237
Brugia malayi	Pre-SET motif family protein	0.003	0.0034	0.0034
Trypanosoma brucei	Pseudokinase, putative	0.0886	0.3955	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.2206	1	1
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.132	0.594	0.594
Echinococcus granulosus	tyrosine protein kinase csk	0.0886	0.3955	0.3955

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	> 10 uM	Antagonist activity at human mineralocorticoid receptor assessed as inhibition of binding to coactivator peptide by NH Pro assay	ChEMBL.	23777778

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2407657

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1773157