Detailed information for compound 1773753

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 492.573 | Formula: C32H24N6
  • H donors: 0 H acceptors: 4 LogP: 6.47 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc2c(c1)cc(cc2)Cn1nnc(c1)c1ccc(cc1)c1nnn(c1)Cc1ccc2c(c1)cccc2
  • InChi: 1S/C32H24N6/c1-3-7-29-17-23(9-11-25(29)5-1)19-37-21-31(33-35-37)27-13-15-28(16-14-27)32-22-38(36-34-32)20-24-10-12-26-6-2-4-8-30(26)18-24/h1-18,21-22H,19-20H2
  • InChiKey: YOQOISBIHNWQPN-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0049 0.0345 0.0626
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Onchocerca volvulus 0.0134 0.1447 0.2801
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0152 0.0287
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0125 0.1328 0.2412
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.041 0.4991 0.9822
Loa Loa (eye worm) hypothetical protein 0.0239 0.2793 0.5073
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0032 0.0127 0.0234
Trypanosoma cruzi casein kinase, putative 0.0047 0.0318 0.0609
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0339
Echinococcus granulosus Protein kinase C brain isozyme 0.0041 0.0246 0.0473
Leishmania major casein kinase, putative 0.0047 0.0318 0.0609
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0064 0.0547 0.1872
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.0258 0.3035 0.5512
Brugia malayi casein kinase 1, delta 0.0047 0.0318 0.0577
Echinococcus granulosus aurora kinase A 0.0064 0.0547 0.1065
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0109 0.1116 0.111
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0049 0.0345 0.0663
Loa Loa (eye worm) TK/EGFR protein kinase 0.007 0.0614 0.1115
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0075 0.0677 0.1322
Loa Loa (eye worm) hypothetical protein 0.0117 0.1222 0.2219
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0032 0.0127 0.0231
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0024 0.0033 0.0027
Brugia malayi cyclin-dependent kinase 7 homolog 0.0084 0.0805 0.1462
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0064 0.0547 0.1065
Entamoeba histolytica casein kinase, putative 0.0047 0.0318 0.1075
Brugia malayi Fibronectin type III domain containing protein 0.0032 0.0127 0.023
Plasmodium falciparum calcium-dependent protein kinase 5 0.0046 0.0316 0.2292
Echinococcus multilocularis 0.0068 0.0595 0.0589
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0178 0.2007 0.394
Entamoeba histolytica protein kinase, putative 0.0034 0.0152 0.0498
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0025 0.0042 0.007
Schistosoma mansoni hypothetical protein 0.0027 0.0072 0.0129
Echinococcus granulosus serine:threonine kinase SAD 1 0.0032 0.0127 0.0239
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.0178 0.2007 0.394
Echinococcus multilocularis protein kinase c epsilon type 0.0041 0.0246 0.024
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0023 0.0009 0.0005
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0122 0.1286 0.2522
Schistosoma mansoni tyrosine kinase 0.0139 0.1508 0.2958
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0047 0.0318 0.0577
Toxoplasma gondii AGC kinase 0.0034 0.0152 0.1068
Entamoeba histolytica protein kinase domain containing protein 0.0064 0.0547 0.1872
Brugia malayi Cam kinase protein 1 0.0046 0.0316 0.0574
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0316 0.031
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0417 0.5082 1
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0025 0.0042 0.0035
Onchocerca volvulus 0.0151 0.1665 0.3233
Echinococcus granulosus casein kinase I alpha 0.0047 0.0318 0.0613
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0109 0.1116 0.111
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0109 0.1116 0.2186
Brugia malayi hypothetical protein 0.0027 0.0072 0.013
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0032 0.0127 0.0234
Giardia lamblia Kinase, CK1 Casein kinase 0.0047 0.0318 0.0971
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0152 0.0287
Toxoplasma gondii casein kinase I 0.0047 0.0318 0.2305
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0091 0.0894 0.1745
Echinococcus granulosus hypothetical protein 0.0117 0.1222 0.2395
Schistosoma mansoni protein kinase 0.0154 0.1698 0.3334
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0139 0.1508 0.1502
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0316 0.061
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0067 0.0578 0.1127
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0183 0.207 0.3759
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0064 0.0547 0.1872
Giardia lamblia Aurora kinase 0.0064 0.0547 0.1778
Trichomonas vaginalis AGC family protein kinase 0.0049 0.0345 0.192
Entamoeba histolytica PH domain containing protein kinase, putative 0.0049 0.0345 0.1169
Echinococcus granulosus dual specificity 0.0183 0.207 0.4066
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0025 0.0042 0.007
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0049 0.0345 0.2508
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0049 0.0345 0.0663
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0024 0.0033 0.0053
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0183 0.207 0.4063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0046 0.0316 0.061
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0049 0.0345 0.0663
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0185 0.2103 0.3819
Schistosoma mansoni protein kinase 0.0079 0.074 0.1446
Plasmodium falciparum glycogen synthase kinase 3 0.0103 0.1038 0.768
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0417 0.5082 1
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0024 0.0033 0.0048
Trichomonas vaginalis CK1 family protein kinase 0.0047 0.0318 0.1757
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0069 0.0609 0.1106
Echinococcus granulosus protein kinase c iota type 0.0041 0.0246 0.0473
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0178 0.2007 0.394
Schistosoma mansoni tyrosine kinase 0.0057 0.0452 0.0877
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Giardia lamblia Kinase, CMGC CLK 0.0127 0.1349 0.46
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0046 0.0316 0.0574
Entamoeba histolytica protein kinase, putative 0.0103 0.1038 0.3581
Brugia malayi hypothetical protein 0.0032 0.0127 0.023
Schistosoma mansoni tyrosine kinase 0.0057 0.0452 0.0877
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0083 0.0781 0.1527
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0805 0.1573
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0246 0.2884 1
Echinococcus granulosus NDR protein kinase 0.0034 0.0152 0.0287
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0082 0.0775 0.1408
Echinococcus granulosus dual specificity mitogen activated protein 0.0258 0.3035 0.5967
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.1446 0.2838
Schistosoma mansoni hypothetical protein 0.0024 0.0033 0.0053
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0046 0.0316 0.2292
Brugia malayi Immunoglobulin I-set domain containing protein 0.0114 0.1183 0.2148
Plasmodium falciparum calcium-dependent protein kinase 4 0.0046 0.0316 0.2292
Brugia malayi Protein kinase domain containing protein 0.0183 0.207 0.3759
Brugia malayi Furin-like cysteine rich region family protein 0.007 0.0614 0.1115
Echinococcus granulosus Vam6:Vps39 protein 0.0024 0.0033 0.0053
Entamoeba histolytica protein kinase, putative 0.0025 0.0042 0.0115
Brugia malayi serine/threonine-protein kinase 6 0.0064 0.0547 0.0993
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0183 0.207 0.4063
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0034 0.0152 0.0146
Onchocerca volvulus 0.0134 0.1447 0.2801
Leishmania major protein kinase, putative 0.0127 0.1349 0.2642
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0064 0.0547 0.3434
Trypanosoma cruzi casein kinase, putative 0.0047 0.0318 0.0609
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0107 0.1101 0.2
Brugia malayi Protein kinase domain 0.0025 0.0042 0.0076
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0339
Plasmodium falciparum casein kinase 1 0.0047 0.0318 0.2305
Schistosoma mansoni atypical protein kinase C 0.0041 0.0246 0.0473
Loa Loa (eye worm) AUR protein kinase 0.0064 0.0547 0.0993
Entamoeba histolytica protein kinase, putative 0.0046 0.0316 0.1069
Brugia malayi Protein kinase domain containing protein 0.0034 0.0161 0.0292
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0125 0.1328 0.2412
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0125 0.1328 0.2604
Echinococcus multilocularis casein kinase I alpha 0.0047 0.0318 0.0311
Trypanosoma cruzi aurora B kinase, putative 0.0064 0.0547 0.1061
Schistosoma mansoni tyrosine kinase 0.0139 0.1508 0.2958
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0345 0.0667
Echinococcus granulosus casein kinase I delta 0.0047 0.0318 0.0613
Entamoeba histolytica protein kinase, putative 0.0064 0.0547 0.1872
Onchocerca volvulus 0.0037 0.019 0.0311
Giardia lamblia Kinase, CAMK CAMKL 0.0032 0.0127 0.0302
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0178 0.2007 0.394
Schistosoma mansoni protein kinase 0.0034 0.0161 0.0304
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.0417 0.5082 0.5078
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0103 0.1038 0.1032
Trichomonas vaginalis STE family protein kinase 0.0025 0.0042 0.0103
Echinococcus granulosus MAM 0.0027 0.0072 0.0129
Plasmodium vivax calcium-dependent protein kinase, putative 0.0046 0.0316 0.1543
Giardia lamblia Kinase, AGC PKA 0.0049 0.0345 0.1067
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0183 0.207 0.4063
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0046 0.0316 0.0574
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0316 0.031
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0115 0.1199 0.2178
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0255 0.049
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0547 0.313
Brugia malayi probable protein kinase 0.0093 0.0909 0.1651
Echinococcus multilocularis protein kinase shaggy 0.0103 0.1038 0.1032
Schistosoma mansoni cell adhesion molecule 0.0038 0.0212 0.0405
Schistosoma mansoni hypothetical protein 0.0027 0.0072 0.0129
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0025 0.0042 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.023
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.207 0.4066
Schistosoma mansoni rap gtpase-activating protein 0.0024 0.0033 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.023
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Loa Loa (eye worm) TK/FAK protein kinase 0.0261 0.307 0.5576
Echinococcus multilocularis PAK box P21 Rho binding 0.0025 0.0042 0.0035
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0246 0.0473
Echinococcus granulosus casein kinase I alpha 0.0047 0.0318 0.0613
Brugia malayi serine/threonine protein kinase 6 0.0064 0.0547 0.0993
Brugia malayi serine/threonine-protein kinase PAK 7 0.0187 0.2131 0.387
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0122 0.1286 0.2337
Echinococcus granulosus roundabout 2 0.0044 0.0279 0.0537
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.0246 0.2884 0.5
Schistosoma mansoni serine/threonine kinase 0.0034 0.0152 0.0287
Loa Loa (eye worm) TK/INSR protein kinase 0.0139 0.1508 0.2738
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Echinococcus granulosus twitchin 0.0047 0.0321 0.062
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0547 0.313
Echinococcus multilocularis serine:threonine protein kinase 38 0.0034 0.0152 0.0146
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.1038 0.6072
Echinococcus multilocularis 0.0117 0.1222 0.1216
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Brugia malayi protein kinase C II. 0.0041 0.0246 0.0448
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0103 0.1038 0.2033
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0547 0.313
Giardia lamblia Kinase, CMGC GSK 0.0103 0.1038 0.3506
Plasmodium falciparum serine/threonine protein kinase KIN 0.0032 0.0127 0.0886
Brugia malayi putative serine/threonine kinase SADA gamma 0.0032 0.0127 0.0231
Schistosoma mansoni protein kinase 0.0258 0.3035 0.5967
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0039 0.0217 0.0211
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0049 0.0345 0.0663
Entamoeba histolytica protein kinase, putative 0.0183 0.207 0.7169
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0032 0.0127 0.0234
Entamoeba histolytica protein kinase, putative 0.0025 0.0042 0.0115
Schistosoma mansoni tyrosine kinase 0.0028 0.0076 0.0138
Onchocerca volvulus 0.0417 0.5082 1
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0042 0.0255 0.049
Trichomonas vaginalis STE family protein kinase 0.0025 0.0042 0.0103
Echinococcus granulosus cyclin dependent kinase 7 0.0084 0.0805 0.1573
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.1038 0.3581
Onchocerca volvulus 0.0103 0.1038 0.1991
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0032 0.0127 0.0121
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0046 0.0316 0.0606
Echinococcus multilocularis activated cdc42 kinase 1 0.0173 0.1949 0.1944
Giardia lamblia Kinase, CMGC GSK 0.0103 0.1038 0.3506
Plasmodium falciparum protein serine/threonine kinase-1 0.0127 0.1349 1
Echinococcus granulosus dual specificity protein kinase clk2 0.0127 0.1349 0.2646
Giardia lamblia Hypothetical protein 0.0246 0.2884 1
Brugia malayi Protein kinase domain containing protein 0.0242 0.2827 0.5135
Entamoeba histolytica protein kinase , putative 0.0064 0.0547 0.1872
Loa Loa (eye worm) hypothetical protein 0.0134 0.1447 0.2628
Echinococcus granulosus casein kinase I alpha 0.0047 0.0318 0.0613
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0154 0.1698 0.3334
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0046 0.0316 0.1543
Loa Loa (eye worm) AGC/PKA protein kinase 0.0049 0.0345 0.0626
Leishmania major protein kinase A catalytic subunit isoform 2 0.0049 0.0345 0.0663
Echinococcus multilocularis dual specificity mitogen activated protein 0.0258 0.3035 0.303
Schistosoma mansoni protein kinase 0.0047 0.0318 0.0613
Loa Loa (eye worm) hypothetical protein 0.0046 0.0316 0.0574
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0127 0.1349 0.2642
Brugia malayi Protein kinase domain containing protein 0.0127 0.1349 0.245
Loa Loa (eye worm) hypothetical protein 0.0134 0.1447 0.2628
Echinococcus multilocularis rho associated protein kinase 0.0151 0.1665 0.166
Trypanosoma cruzi casein kinase, putative 0.0047 0.0318 0.0609
Schistosoma mansoni vesicular amine transporter 0.0032 0.0127 0.0237
Loa Loa (eye worm) AGC/PKA protein kinase 0.0049 0.0345 0.0626
Brugia malayi p70 ribosomal S6 kinase beta 0.0034 0.0152 0.0276
Brugia malayi hypothetical protein 0.0059 0.0481 0.0874
Loa Loa (eye worm) TK protein kinase 0.0114 0.1183 0.2148
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0034 0.0161 0.0154
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0066 0.0573 0.1041
Schistosoma mansoni nephrin 0.0037 0.0194 0.0369
Brugia malayi bone morphogenetic protein type 1 receptor 0.0082 0.0775 0.1408
Schistosoma mansoni tyrosine kinase 0.0258 0.3032 0.5963
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0047 0.0318 0.0577
Echinococcus multilocularis casein kinase I delta 0.0047 0.0318 0.0311
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0038 0.0212 0.0405
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0122 0.1286 0.2337
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0068 0.0595 0.108
Echinococcus granulosus TGF beta receptor type 1 0.0079 0.074 0.1446
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0134 0.1446 0.2627
Schistosoma mansoni serine/threonine protein kinase 0.0125 0.1328 0.2604
Trypanosoma brucei SNF1-related protein kinases, putative 0.0032 0.0127 0.0234
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Echinococcus multilocularis serine threonine protein kinase 0.0034 0.0152 0.0146
Loa Loa (eye worm) AUR protein kinase 0.0064 0.0547 0.0993
Brugia malayi Temporarily assigned gene name protein 59 0.0024 0.0033 0.006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0279 0.0507
Echinococcus granulosus activin receptor type 0.0377 0.4574 0.8999
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Entamoeba histolytica protein kinase, putative 0.0025 0.0042 0.0115
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0127 0.1349 0.2642
Echinococcus multilocularis serine:threonine protein kinase N2 0.0034 0.0152 0.0146
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0032 0.0127 0.012
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0034 0.0161 0.0304
Loa Loa (eye worm) hypothetical protein 0.0038 0.0212 0.0385
Brugia malayi Protein kinase domain containing protein 0.0082 0.0775 0.1408
Brugia malayi Protein kinase domain containing protein 0.0261 0.307 0.5576
Echinococcus multilocularis epidermal growth factor receptor 0.007 0.0614 0.0608
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0049 0.0345 0.2508
Brugia malayi serine/threonine kinase 12 0.0064 0.0547 0.0993
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0034 0.0152 0.0287
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0034 0.0152 0.0146
Trypanosoma brucei casein kinase I, isoform 2 0.0047 0.0318 0.0609
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.1038 0.6072
Onchocerca volvulus 0.0027 0.0072 0.0076
Schistosoma mansoni protein kinase 0.0025 0.0042 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0127 0.0239
Echinococcus multilocularis transfer RNA-Thr 0.0173 0.1949 0.1944
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0339
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0127 0.0239
Plasmodium vivax casein kinase 1, putative 0.0047 0.0318 0.1557
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0127 0.0239
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0091 0.0894 0.1623
Leishmania major protein kinase, putative 0.0127 0.1349 0.2642
Loa Loa (eye worm) STE/STE7/MEK7 protein kinase 0.0258 0.3035 0.5512
Trichomonas vaginalis STE family protein kinase 0.0025 0.0042 0.0103
Echinococcus granulosus TGF-beta receptor type-1 0.0079 0.074 0.1446
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0172 0.1935 0.193
Toxoplasma gondii AGC kinase 0.0049 0.0345 0.2508
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0152 0.0287
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0024 0.0033 0.0053
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0046 0.0316 0.061
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.013
Echinococcus multilocularis calcium dependent protein kinase 0.0037 0.0188 0.0182
Schistosoma mansoni protein kinase 0.0023 0.0009 0.0005
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0066 0.0573 0.0567
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0034 0.0152 0.0287
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Trichomonas vaginalis STE family protein kinase 0.0025 0.0042 0.0103
Brugia malayi casein kinase I 0.0047 0.0318 0.0577
Loa Loa (eye worm) hypothetical protein 0.0173 0.1949 0.3539
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0255 0.049
Entamoeba histolytica protein kinase, putative 0.0183 0.207 0.7169
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0316 0.1746
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.041 0.4991 0.9822
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0154 0.1698 0.1693
Entamoeba histolytica protein kinase, putative 0.0046 0.0316 0.1069
Trichomonas vaginalis STE family protein kinase 0.0025 0.0042 0.0103
Plasmodium falciparum calcium-dependent protein kinase 1 0.0046 0.0316 0.2292
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0032 0.0127 0.0234
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0037 0.019 0.0358
Schistosoma mansoni protein kinase 0.0025 0.0042 0.007
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0034 0.0161 0.0154
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Brugia malayi Protein kinase domain containing protein 0.045 0.5506 1
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Onchocerca volvulus Tyrosine kinase homolog 0.0152 0.1676 0.3255
Echinococcus multilocularis protein KINase family member (kin 25) 0.0075 0.0677 0.0671
Echinococcus multilocularis MAM 0.0027 0.0072 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.1349 0.7935
Entamoeba histolytica protein kinase, putative 0.0034 0.0152 0.0498
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.013
Echinococcus multilocularis dual specificity mitogen activated protein 0.0154 0.1694 0.1689
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0049 0.0345 0.1779
Echinococcus multilocularis dual specificity 0.0183 0.207 0.2065
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0103 0.1038 0.1886
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0127 0.1349 0.2642
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0006 0.0012
Echinococcus granulosus insulin receptor 0.0139 0.1508 0.2958
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.007 0.0614 0.1197
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0069 0.0609 0.1106
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0127 0.1349 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0049 0.0345 0.1169
Loa Loa (eye worm) AGC/NDR protein kinase 0.0034 0.0152 0.0276
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0154 0.1694 0.3322
Loa Loa (eye worm) hypothetical protein 0.0075 0.0677 0.123
Brugia malayi Protein kinase domain containing protein 0.0034 0.0152 0.0276
Entamoeba histolytica protein kinase, putative 0.0034 0.0152 0.0498
Toxoplasma gondii AGC kinase 0.0049 0.0345 0.2508
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0084 0.0805 0.1462
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0667
Schistosoma mansoni protein kinase 0.0023 0.0009 0.0005
Plasmodium falciparum calcium-dependent protein kinase 3 0.0046 0.0316 0.2292
Loa Loa (eye worm) hypothetical protein 0.0173 0.1942 0.3528
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0041 0.0246 0.024
Echinococcus granulosus serine:threonine protein kinase N2 0.0034 0.0152 0.0287
Schistosoma mansoni tyrosine kinase 0.0024 0.0034 0.0054
Schistosoma mansoni 6-phosphofructokinase 0.0417 0.5082 1
Echinococcus multilocularis neuroglian 0.0037 0.0194 0.0187
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0187 0.2131 0.387
Trypanosoma brucei protein kinase, putative 0.0103 0.1038 0.2029
Loa Loa (eye worm) hypothetical protein 0.041 0.4991 0.9065
Giardia lamblia Kinase, CAMK CAMKL 0.0032 0.0127 0.0302
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0139 0.1508 0.2958
Leishmania major protein kinase, putative 0.0064 0.0547 0.1061
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0107 0.1101 0.2
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0172 0.1935 0.3801
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0416 0.5066 0.9969
Echinococcus multilocularis activin receptor type 0.0377 0.4574 0.457
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0025 0.0042 0.0035
Schistosoma mansoni tyrosine kinase 0.0075 0.0677 0.1322
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0046 0.0316 0.1543
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Brugia malayi Protein kinase domain containing protein 0.0034 0.0152 0.0276
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0115 0.1199 0.235
Plasmodium falciparum serine/threonine protein kinase, putative 0.0064 0.0547 0.4016
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0024 0.0033 0.0048
Loa Loa (eye worm) hypothetical protein 0.0059 0.0481 0.0874
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0046 0.0316 0.2292
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0023 0.0009 0.0002
Entamoeba histolytica protein kinase, putative 0.0025 0.0042 0.0115
Echinococcus multilocularis casein kinase i 0.0047 0.0318 0.0311
Echinococcus multilocularis aurora kinase A 0.0064 0.0547 0.0541
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0046 0.0316 0.2292
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0318 0.0613
Giardia lamblia Kinase, STE STE20 0.0154 0.1694 0.5813
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0034 0.0161 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0547 0.1065
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0127 0.1349 0.2642
Echinococcus multilocularis casein kinase I delta 0.0047 0.0318 0.0311
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0041 0.0246 0.0448
Trichomonas vaginalis CK1 family protein kinase 0.0047 0.0318 0.1757
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0046 0.0316 0.1543
Leishmania major protein kinase, putative 0.0046 0.0316 0.0606
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Loa Loa (eye worm) TK/ALK protein kinase 0.0242 0.2826 0.5133
Brugia malayi Protein kinase domain containing protein 0.0066 0.0573 0.1041
Loa Loa (eye worm) hypothetical protein 0.0202 0.2311 0.4198
Schistosoma mansoni protein kinase 0.0093 0.0909 0.1778
Trichomonas vaginalis CK1 family protein kinase 0.0047 0.0318 0.1757
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0032 0.0127 0.0237
Entamoeba histolytica serine/threonine protein kinase, putative 0.0032 0.0127 0.0413
Onchocerca volvulus 0.0027 0.0072 0.0076
Schistosoma mansoni protein kinase 0.0082 0.0775 0.1515
Schistosoma mansoni serine/threonine protein kinase 0.0115 0.1199 0.235
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.1349 0.2646
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0246 0.0473
Schistosoma mansoni protein kinase 0.0064 0.0547 0.1065
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0032 0.0127 0.0237
Echinococcus granulosus epidermal growth factor receptor 0.007 0.0614 0.1197
Loa Loa (eye worm) hypothetical protein 0.0173 0.1942 0.3528
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0025 0.0042 0.0035
Entamoeba histolytica casein kinase 1, putative 0.0047 0.0318 0.1075
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0154 0.1694 0.3322
Echinococcus granulosus tyrosine protein kinase Lyn 0.0027 0.0071 0.0128
Loa Loa (eye worm) hypothetical protein 0.0168 0.188 0.3415
Schistosoma mansoni serine/threonine protein kinase 0.0028 0.0076 0.0138
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0049 0.0345 0.0663
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0046 0.0316 0.061
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0032 0.0127 0.0234
Echinococcus granulosus dual specificity mitogen activated protein 0.0154 0.1694 0.3325
Echinococcus granulosus casein kinase i 0.0047 0.0318 0.0613
Echinococcus granulosus fibroblast growth factor receptor 4 0.0109 0.1116 0.2186
Schistosoma mansoni protein kinase 0.0023 0.0009 0.0005
Echinococcus multilocularis protein kinase c iota type 0.0041 0.0246 0.024
Echinococcus multilocularis epidermal growth factor receptor 0.007 0.0614 0.0608
Giardia lamblia Kinase, AGC AKT 0.0091 0.0894 0.2998
Schistosoma mansoni vam6/vps39 related 0.0024 0.0033 0.0053
Schistosoma mansoni protein kinase 0.0154 0.1698 0.3334
Entamoeba histolytica p21-activated kinase 0.0025 0.0042 0.0115
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0046 0.0316 0.0574
Brugia malayi Dual specificity mitogen-activated protein kinase kinase 7. -TRUNCATED- 0.0258 0.3035 0.5512
Loa Loa (eye worm) hypothetical protein 0.0069 0.0613 0.1113
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0183 0.207 0.4063
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0127 0.1349 0.245
Loa Loa (eye worm) hypothetical protein 0.0062 0.0515 0.0935
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0127 0.023
Schistosoma mansoni tyrosine kinase 0.007 0.0614 0.1197
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Echinococcus multilocularis roundabout 2 0.0044 0.0279 0.0273
Echinococcus multilocularis insulin receptor 0.0139 0.1508 0.1502
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.041 0.4991 0.9822
Echinococcus multilocularis Immunoglobulin 0.0032 0.0127 0.012
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0122 0.1286 0.1281
Schistosoma mansoni tyrosine kinase 0.007 0.0614 0.1197
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Leishmania major protein kinase A catalytic subunit 0.0049 0.0345 0.0663
Entamoeba histolytica protein kinase, putative 0.0034 0.0152 0.0498
Echinococcus granulosus rho-associated protein kinase 1 0.0151 0.1665 0.3269
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0049 0.0345 0.0663
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0034 0.0161 0.0292
Loa Loa (eye worm) hypothetical protein 0.0417 0.5082 0.923
Echinococcus granulosus epidermal growth factor receptor 0.007 0.0614 0.1197
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0115 0.1199 0.1194
Entamoeba histolytica hypothetical protein 0.0183 0.207 0.7169
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0049 0.0345 0.0663
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.1038 0.3581
Loa Loa (eye worm) hypothetical protein 0.0142 0.1542 0.28
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0667
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.0231
Schistosoma mansoni protein kinase 0.0068 0.0595 0.1159
Echinococcus granulosus protein kinase C gamma type 0.0034 0.0152 0.0287
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.023
Schistosoma mansoni tyrosine kinase 0.0109 0.1116 0.2186
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0154 0.1694 0.3077
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0079 0.074 0.0734
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0024 0.0033 0.0053
Echinococcus granulosus protein kinase c epsilon type 0.0041 0.0246 0.0473
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0154 0.1694 0.3077
Loa Loa (eye worm) hypothetical protein 0.0049 0.0345 0.0626
Brugia malayi Protein kinase domain containing protein 0.0173 0.1949 0.3539
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0047 0.0318 0.0609
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.023
Plasmodium falciparum calcium-dependent protein kinase 2 0.0046 0.0316 0.2292
Trypanosoma cruzi casein kinase, putative 0.0047 0.0318 0.0609
Echinococcus multilocularis dual specificity protein kinase clk2 0.0127 0.1349 0.1344
Loa Loa (eye worm) AGC/PKN protein kinase 0.0034 0.0152 0.0276
Onchocerca volvulus 0.0047 0.0318 0.0564
Loa Loa (eye worm) hypothetical protein 0.0027 0.0072 0.013
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0064 0.0547 0.1872
Brugia malayi Protein kinase domain containing protein 0.0034 0.0152 0.0276
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0154 0.1694 0.3322
Loa Loa (eye worm) hypothetical protein 0.0062 0.0515 0.0935
Brugia malayi protein C17H12.11 0.0059 0.0481 0.0874
Onchocerca volvulus 0.0141 0.1538 0.2981
Echinococcus granulosus activated cdc42 kinase 1 0.0173 0.1949 0.3827
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0042 0.0255 0.0249
Brugia malayi Immunoglobulin I-set domain containing protein 0.0185 0.2103 0.3819
Echinococcus multilocularis serine:threonine protein kinase N2 0.0034 0.0152 0.0146
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0034 0.0152 0.0276
Schistosoma mansoni tyrosine kinase 0.007 0.0614 0.1197
Echinococcus multilocularis casein kinase I alpha 0.0047 0.0318 0.0311
Trichomonas vaginalis STE family protein kinase 0.0154 0.1694 1
Loa Loa (eye worm) AUR protein kinase 0.0064 0.0547 0.0993
Schistosoma mansoni protein kinase 0.0025 0.0042 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0345 0.0667
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0103 0.1038 0.2029
Echinococcus granulosus calcium dependent protein kinase 0.0037 0.0188 0.0359
Echinococcus granulosus neuroglian 0.0037 0.0194 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0151 0.1665 0.3269
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0103 0.1038 0.1886
Loa Loa (eye worm) hypothetical protein 0.0032 0.0127 0.023
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0417 0.5082 1
Plasmodium vivax glycogen synthase kinase 3, putative 0.0103 0.1038 0.7455
Trypanosoma cruzi casein kinase, putative 0.0047 0.0318 0.0609
Echinococcus granulosus Immunoglobulin 0.0032 0.0127 0.0237
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.006
Trypanosoma brucei rac serine-threonine kinase, putative 0.0034 0.0152 0.0282
Brugia malayi Protein kinase domain containing protein 0.0069 0.0609 0.1106
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0127 0.1349 0.2642
Trichomonas vaginalis STE family protein kinase 0.0154 0.1694 1
Trichomonas vaginalis STE family protein kinase 0.0154 0.1694 1
Leishmania major protein kinase A catalytic subunit isoform 1 0.0049 0.0345 0.0663
Echinococcus granulosus activated cdc42 kinase 1 0.0173 0.1949 0.3827
Brugia malayi Protein kinase domain containing protein 0.0139 0.1508 0.2738
Brugia malayi Hr1 repeat family protein 0.0034 0.0152 0.0276
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0103 0.1038 0.2033
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0034 0.0152 0.0276
Echinococcus multilocularis protein tyrosine kinase 0.0258 0.3032 0.3028
Brugia malayi intracellular kinase 0.0103 0.1038 0.1886
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0127 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0127 0.0618
Schistosoma mansoni protein kinase 0.0154 0.1698 0.3334
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0103 0.1038 0.768
Echinococcus granulosus 6 phosphofructo 2 kinase:fructose 2 0.0417 0.5082 1
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0034 0.0152 0.0276
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.041 0.4991 0.9822
Echinococcus multilocularis cyclin dependent kinase 7 0.0084 0.0805 0.0799
Loa Loa (eye worm) hypothetical protein 0.0083 0.0781 0.1419
Schistosoma mansoni protein kinase 0.0154 0.1694 0.3325
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0417 0.5082 1
Entamoeba histolytica protein kinase domain containing protein 0.0183 0.207 0.7169
Schistosoma mansoni serine/threonine protein kinase 0.0084 0.0805 0.1573
Echinococcus multilocularis casein kinase I alpha 0.0047 0.0318 0.0311
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0345 0.0667
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0122 0.1286 0.2337
Trichomonas vaginalis AGC family protein kinase 0.0064 0.0547 0.313
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0667
Plasmodium vivax serine/threonine kinase-1, putative 0.0127 0.1349 1
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.045 0.5506 1
Echinococcus multilocularis TGF beta receptor type 1 0.0079 0.074 0.0734
Toxoplasma gondii aurora kinase 0.0064 0.0547 0.4016
Echinococcus granulosus casein kinase I delta 0.0047 0.0318 0.0613
Brugia malayi hypothetical protein 0.0024 0.0033 0.006
Loa Loa (eye worm) AGC/AKT protein kinase 0.0034 0.0152 0.0276
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0047 0.0318 0.0577
Entamoeba histolytica protein kinase, putative 0.0064 0.0547 0.1872
Loa Loa (eye worm) hypothetical protein 0.0134 0.1447 0.2628
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0127 0.1349 0.2642
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Echinococcus multilocularis Immunoglobulin 0.0032 0.0127 0.012
Giardia lamblia Hypothetical protein 0.0246 0.2884 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0049 0.0345 0.0339
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0064 0.0547 0.0541
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0316 0.031
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0134 0.1446 0.2627
Trichomonas vaginalis AGC family protein kinase 0.0034 0.0152 0.0763
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0125 0.1328 0.1322
Loa Loa (eye worm) hypothetical protein 0.0044 0.0279 0.0507
Loa Loa (eye worm) hypothetical protein 0.0161 0.1786 0.3244
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0039 0.0217 0.0416
Schistosoma mansoni tyrosine kinase 0.0057 0.0452 0.0877
Echinococcus granulosus protein kinase 0.0068 0.0595 0.1159
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0103 0.1038 0.2029
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0246 0.0473
Echinococcus granulosus protein tyrosine kinase 0.0258 0.3032 0.5963
Trypanosoma brucei aurora B kinase 0.0064 0.0547 0.1061
Loa Loa (eye worm) hypothetical protein 0.0032 0.0128 0.0232
Echinococcus granulosus defective proboscis extension response 0.0032 0.0127 0.0237
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.1349 0.2646
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0024 0.0033 0.0048
Echinococcus granulosus protein kinase shaggy 0.0103 0.1038 0.2033
Mycobacterium ulcerans hypothetical protein 0.0246 0.2884 0.5
Toxoplasma gondii histone kinase SNF1, putative 0.0032 0.0127 0.0886

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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