Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Onchocerca volvulus | 0.0672 | 0.107 | 1 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0672 | 0.107 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0672 | 0.107 | 0.1609 |
Echinococcus multilocularis | acetylcholinesterase | 0.3975 | 0.6653 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0672 | 0.107 | 0.1609 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0672 | 0.107 | 0.1609 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0672 | 0.107 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.5955 | 1 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0672 | 0.107 | 0.1609 |
Echinococcus multilocularis | acetylcholinesterase | 0.3975 | 0.6653 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3975 | 0.6653 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3975 | 0.6653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3975 | 0.6653 | 0.6653 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0672 | 0.107 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.5955 | 1 | 1 |
Onchocerca volvulus | 0.0672 | 0.107 | 1 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3975 | 0.6653 | 0.6653 |
Echinococcus granulosus | acetylcholinesterase | 0.3975 | 0.6653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3975 | 0.6653 | 0.6653 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0672 | 0.107 | 0.1609 |
Brugia malayi | Carboxylesterase family protein | 0.0672 | 0.107 | 0.107 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0672 | 0.107 | 0.1609 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0672 | 0.107 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0672 | 0.107 | 0.107 |
Brugia malayi | Carboxylesterase family protein | 0.3975 | 0.6653 | 0.6653 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0672 | 0.107 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.5955 | 1 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.3975 | 0.6653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3975 | 0.6653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.3044 | 0.5079 | 0.5079 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0672 | 0.107 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0672 | 0.107 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0672 | 0.107 | 0.1609 |
Echinococcus multilocularis | neuroligin | 0.0672 | 0.107 | 0.1609 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0672 | 0.107 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0672 | 0.107 | 0.107 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0672 | 0.107 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0672 | 0.107 | 0.1609 |
Onchocerca volvulus | 0.0672 | 0.107 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0672 | 0.107 | 0.1609 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0672 | 0.107 | 0.1609 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.5955 | 1 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.3975 | 0.6653 | 0.6653 |
Brugia malayi | Carboxylesterase family protein | 0.3975 | 0.6653 | 0.6653 |
Onchocerca volvulus | 0.0672 | 0.107 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0672 | 0.107 | 0.107 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0672 | 0.107 | 0.1609 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Loa Loa (eye worm) | carboxylesterase | 0.0672 | 0.107 | 0.107 |
Brugia malayi | Carboxylesterase family protein | 0.0672 | 0.107 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.0672 | 0.107 | 0.107 |
Onchocerca volvulus | 0.0672 | 0.107 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.