Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0038 | 0.0826 |
Onchocerca volvulus | 0.0031 | 0.0057 | 0.0199 | |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0023 | 0.0018 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0046 | 0.0104 | 0.0487 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.002 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0048 | 0.0173 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0016 | 0.0014 | 0.0014 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0082 | 0.0354 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0157 | 0.0153 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0024 | 0.0011 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.0174 | 0.0174 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0094 | 0.0248 | 0.0621 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0023 | 0.0009 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0024 | 0.0011 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0566 | 0.1661 | 0.1657 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0089 | 0.0232 | 0.0232 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.002 | 0.0026 | 0.0038 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0089 | 0.0232 | 0.0232 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.002 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0024 | 0.0011 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0046 | 0.0104 | 0.009 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0123 | 0.0109 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0023 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | histone methyltransferase | 0.0027 | 0.0047 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0024 | 0.0024 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.068 | 0.4026 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0024 | 0.0024 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0161 | 0.0448 | 1 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0016 | 0.0014 | 0.0009 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0024 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0232 | 0.0218 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0024 | 0.0024 |
Mycobacterium ulcerans | oxidoreductase | 0.0094 | 0.0248 | 0.0577 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0023 | 0.0009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0024 | 0.0024 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0022 | 0.0031 | 0.0027 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.0023 | 0.0021 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.3349 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.3349 | 1 | 1 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0123 | 0.0109 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0022 | 0.0031 | 0.0018 |
Brugia malayi | CXXC zinc finger family protein | 0.0084 | 0.0218 | 0.0218 |
Schistosoma mansoni | amine oxidase | 0.0094 | 0.0248 | 0.0243 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0157 | 0.0144 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.006 | 0.0046 |
Onchocerca volvulus | 0.0046 | 0.0104 | 0.0487 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0566 | 0.1661 | 0.446 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0024 | 0.0024 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0031 | 0.0018 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.018 | 0.0505 | 0.0501 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0091 | 0.0408 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0566 | 0.1661 | 0.1649 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0094 | 0.0248 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0091 | 0.0435 |
Schistosoma mansoni | hypothetical protein | 0.0399 | 0.1161 | 0.1157 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0566 | 0.1661 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0157 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0024 | 0.0024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0046 | 0.0104 | 0.0104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0232 | 0.0227 |
Schistosoma mansoni | cpg binding protein | 0.0089 | 0.0233 | 0.0228 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.003 | 0.0064 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0024 | 0.0011 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.0157 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0285 | 0.0819 | 0.0815 |
Schistosoma mansoni | acetylcholinesterase | 0.0566 | 0.1661 | 0.1657 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0157 | 0.0144 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0024 | 0.0024 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0023 | 0.5364 |
Brugia malayi | Carboxylesterase family protein | 0.0566 | 0.1661 | 0.1661 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0123 | 0.0123 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0024 | 0.002 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0024 | 0.002 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0566 | 0.1661 | 0.1657 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0024 | 0.0011 |
Echinococcus multilocularis | neuroligin | 0.0566 | 0.1661 | 0.1649 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0038 | 0.0826 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.0157 | 0.0144 |
Brugia malayi | SWIRM domain containing protein | 0.0094 | 0.0248 | 0.0248 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0024 | 0.0011 |
Mycobacterium ulcerans | monoamine oxidase | 0.0094 | 0.0248 | 0.0577 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0038 | 0.0441 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0094 | 0.0248 | 1 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0046 | 0.0104 | 0.009 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0186 | 0.0523 | 0.051 |
Onchocerca volvulus | 0.0043 | 0.0094 | 0.0428 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0203 | 0.0573 | 0.0573 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0566 | 0.1661 | 0.446 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0174 | 0.016 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.006 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.038 | 0.0376 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0084 | 0.0218 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.3349 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0038 | 0.0826 |
Plasmodium vivax | hypothetical protein, conserved | 0.0094 | 0.0248 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0566 | 0.1661 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0024 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0024 | 0.0011 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.0023 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0094 | 0.0248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0057 | 0.0057 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.006 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0024 | 0.0024 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.006 | 0.0046 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0046 | 0.0104 | 0.009 |
Echinococcus multilocularis | cpg binding protein | 0.0089 | 0.0233 | 0.0219 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0038 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0022 | 0.003 | 0.0064 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0024 | 0.0024 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0046 | 0.0104 | 0.009 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0566 | 0.1661 | 0.446 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0023 | 0.0148 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.0157 | 0.0144 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0023 | 0.0148 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0566 | 0.1661 | 0.1649 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0038 | 0.0038 |
Brugia malayi | SET domain containing protein | 0.0014 | 0.0008 | 0.0008 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0023 | 0.0023 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0024 | 0.0024 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0094 | 0.0248 | 0.0235 |
Brugia malayi | Carboxylesterase family protein | 0.0566 | 0.1661 | 0.1661 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0399 | 0.1161 | 0.1149 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Onchocerca volvulus | 0.0566 | 0.1661 | 1 | |
Onchocerca volvulus | 0.0084 | 0.0218 | 0.1186 | |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0094 | 0.0248 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.006 | 0.0055 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0232 | 0.0218 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0174 | 0.016 |
Echinococcus granulosus | dnaJ subfamily B | 0.0399 | 0.1161 | 0.1149 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.1246 | 0.3699 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.006 | 0.006 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.002 | 0.0006 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0051 | 0.0038 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0024 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0024 | 0.002 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0024 | 0.0011 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0174 | 0.016 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0023 | 0.0009 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0566 | 0.1661 | 0.4142 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0038 | 0.0826 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0023 | 0.0009 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0024 | 0.002 |
Onchocerca volvulus | 0.0566 | 0.1661 | 1 | |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0094 | 0.0248 | 0.0235 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0024 | 0.002 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0082 | 0.0381 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.0148 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0023 | 0.5364 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Mycobacterium ulcerans | dehydrogenase | 0.0094 | 0.0248 | 0.0577 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0094 | 0.0248 | 0.0235 |
Onchocerca volvulus | 0.0239 | 0.0681 | 0.4013 | |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0043 | 0.0094 | 0.009 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0022 | 0.0031 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0174 | 0.094 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0123 | 0.0123 |
Brugia malayi | Carboxylesterase family protein | 0.0566 | 0.1661 | 0.1661 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0038 | 0.0826 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0203 | 0.0573 | 0.0573 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0024 | 0.0024 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0094 | 0.0248 | 0.5 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.0157 | 0.0157 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0024 | 0.002 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.002 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | carboxylesterase | 0.0566 | 0.1661 | 0.1661 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0566 | 0.1661 | 0.1649 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0024 | 0.002 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0023 | 0.5364 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0024 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | carboxylesterase | 0.3349 | 1 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0023 | 0.0148 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.0157 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0082 | 0.0381 |
Echinococcus multilocularis | 0.0094 | 0.0248 | 0.0235 | |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0024 | 0.0024 |
Plasmodium vivax | hypothetical protein, conserved | 0.0094 | 0.0248 | 1 |
Brugia malayi | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0091 | 0.0435 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.0174 | 0.0174 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.038 | 0.038 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0094 | 0.0248 | 0.0248 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.006 | 0.0055 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0031 | 0.0057 | 0.0226 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0023 | 0.0023 |
Echinococcus granulosus | acetylcholinesterase | 0.3349 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0024 | 0.0024 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0023 | 0.0009 |
Echinococcus multilocularis | acetylcholinesterase | 0.3349 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0038 | 0.0038 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0048 | 0.0173 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0024 | 0.0024 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1341 | 0.3982 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0139 | 0.038 | 0.038 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0104 | 0.0099 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0123 | 0.0123 |
Echinococcus granulosus | neuroligin | 0.0566 | 0.1661 | 0.1649 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0024 | 0.0024 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0023 | 0.5364 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0047 | 0.0033 |
Brugia malayi | CHD4 protein | 0.0016 | 0.0014 | 0.0014 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.0148 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0023 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Onchocerca volvulus | 0.0566 | 0.1661 | 1 | |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0186 | 0.0523 | 0.051 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0094 | 0.0248 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0566 | 0.1661 | 0.1657 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0232 | 0.0227 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0024 | 0.0024 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0023 | 0.0009 |
Schistosoma mansoni | gliotactin | 0.0566 | 0.1661 | 0.1657 |
Trichomonas vaginalis | helicase, putative | 0.0019 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.006 | 0.006 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.3349 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0024 | 0.0024 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.1341 | 0.3982 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0024 | 0.0011 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0203 | 0.0573 | 0.0573 |
Echinococcus granulosus | cpg binding protein | 0.0089 | 0.0233 | 0.0219 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0791 | 0.2336 | 0.2325 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0094 | 0.0248 | 0.0621 |
Echinococcus granulosus | carboxylesterase 5A | 0.3349 | 1 | 1 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0094 | 0.0248 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Brugia malayi | Carboxylesterase family protein | 0.3349 | 1 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0023 | 0.5364 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0566 | 0.1661 | 0.1649 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0089 | 0.0232 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.3349 | 1 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0023 | 0.0009 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0022 | 0.0031 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0157 | 0.0153 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0024 | 0.002 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0094 | 0.0248 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0094 | 0.0248 | 1 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0094 | 0.0248 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0024 | 0.002 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0094 | 0.0248 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0012 | 0.0012 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0094 | 0.0248 | 0.0235 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0024 | 0.0024 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0123 | 0.0109 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0566 | 0.1661 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0024 | 0.0024 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0024 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0566 | 0.1661 | 0.1661 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.002 | 0.4355 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0024 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0024 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0046 | 0.0104 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.0248 | 0.0248 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0024 | 0.0011 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0174 | 0.0169 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0023 | 0.0023 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0174 | 0.0169 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0038 | 0.0826 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0024 | 0.0011 |
Onchocerca volvulus | 0.0566 | 0.1661 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0024 | 0.0024 |
Schistosoma mansoni | amine oxidase | 0.0094 | 0.0248 | 0.0243 |
Brugia malayi | Carboxylesterase family protein | 0.0566 | 0.1661 | 0.1661 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.006 | 0.0946 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0023 | 0.0018 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.0157 | 0.0153 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0024 | 0.0024 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0027 | 0.0046 | 0.0046 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0024 | 0.0011 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0046 | 0.0104 | 0.0099 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0024 | 0.002 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0566 | 0.1661 | 0.1649 |
Echinococcus multilocularis | acetylcholinesterase | 0.3349 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0084 | 0.0218 | 0.0214 |
Loa Loa (eye worm) | carboxylesterase | 0.0566 | 0.1661 | 0.1661 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0174 | 0.016 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.0148 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.006 | 0.1774 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0024 | 0.002 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.0148 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0089 | 0.0232 | 0.0218 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0123 | 0.0109 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.002 | 0.0015 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0089 | 0.0232 | 0.0218 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.002 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.0023 | 0.0021 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0023 | 0.0009 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0566 | 0.1661 | 0.1657 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0123 | 0.0118 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0022 | 0.0018 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0174 | 0.094 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0024 | 0.0024 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.01 | 0.0263 | 0.5693 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.0023 | 1 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0104 | 0.0104 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0023 | 0.0009 |
Onchocerca volvulus | 0.0094 | 0.0248 | 0.1368 | |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.002 | 0.0015 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0024 | 0.0011 |
Onchocerca volvulus | 0.0566 | 0.1661 | 1 | |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0094 | 0.0248 | 0.5333 |
Leishmania major | UDP-galactopyranose mutase | 0.0094 | 0.0248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.0573 | 0.0573 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0094 | 0.0248 | 0.0243 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0024 | 0.0011 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.002 | 0.0006 |
Echinococcus multilocularis | carboxylesterase 5A | 0.3349 | 1 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0082 | 0.0082 |
Schistosoma mansoni | cpg binding protein | 0.0089 | 0.0233 | 0.0228 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0566 | 0.1661 | 0.1649 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0027 | 0.0047 | 0.0033 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0023 | 0.5364 |
Brugia malayi | mbt repeat family protein | 0.0046 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0082 | 0.0082 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 124.4 uM | Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after 60 mins | ChEMBL. | 23810673 |
IC50 (binding) | = 149.3 uM | Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated for 15 mins measured after 15 mins | ChEMBL. | 23810673 |
IC50 (binding) | = 171.7 uM | Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after 60 mins | ChEMBL. | 23810673 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.