Detailed information for compound 1775688

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 358.471 | Formula: C22H30O4
  • H donors: 0 H acceptors: 2 LogP: 4.93 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC1=CC(=O)C2=C(C1=O)C[C@H]1[C@@](O2)(C)CC[C@@H]2[C@]1(C)CCCC2(C)C
  • InChi: 1S/C22H30O4/c1-20(2)8-6-9-21(3)16(20)7-10-22(4)17(21)11-13-18(24)15(25-5)12-14(23)19(13)26-22/h12,16-17H,6-11H2,1-5H3/t16-,17+,21-,22+/m0/s1
  • InChiKey: HFBFVIXWFQKASY-DEVSCXNHSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2806 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0009
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0053 0.0753
Echinococcus granulosus geminin 0.0346 0.1214 0.1212
Leishmania major hypothetical protein, conserved 0.0047 0.0147 0.0124
Echinococcus multilocularis multidrug resistance protein 1 0.0009 0.0009 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0053 0.0753
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2758 0.9831 0.983
Schistosoma mansoni ferritin 0.0008 0.0007 0.0005
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1197 0.4254 0.4239
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0189 0.0187
Toxoplasma gondii exonuclease III APE 0.0019 0.0045 0.2031
Brugia malayi ecdysone receptor 0.001 0.0013 0.0084
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0053 0.005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0009
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0561 0.0559
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0053 0.005
Echinococcus granulosus phosphoglycerate mutase 0.0047 0.0147 0.0144
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0047 0.0147 0.0121
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0013 0.0011
Mycobacterium leprae probable isochorismate synthase EntC 0.0047 0.0147 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0013 0.0023 0.0816
Loa Loa (eye worm) hypothetical protein 0.0047 0.0147 0.0139
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.248 0.8836 0.8835
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0009 0.0008 0.0006
Brugia malayi regulator of G-protein signaling egl-10 0.0009 0.0008 0.0005
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.3054
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0147 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0023 0.156
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0053 0.005
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0013 0.0011
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus multilocularis cpg binding protein 0.003 0.0083 0.0081
Onchocerca volvulus 0.2806 1 1
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0202 0.0194
Brugia malayi Nuclear hormone receptor E75 0.001 0.0013 0.0084
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0045 0.0022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0053 0.005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0015
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0053 0.005
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0008 0.0005
Mycobacterium tuberculosis Conserved protein 0.0047 0.0147 0.769
Brugia malayi ecdysteroid receptor 0.0021 0.0053 0.0753
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0013 0.0084
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0027 0.0025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0017
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0167 0.8783
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.0143
Loa Loa (eye worm) hypothetical protein 0.0157 0.0537 0.0529
Schistosoma mansoni hypothetical protein 0.0398 0.1399 0.1397
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0053 0.005
Brugia malayi nuclear receptor NHR-88 0.001 0.0013 0.0084
Schistosoma mansoni nuclear receptor 0.001 0.0013 0.0011
Onchocerca volvulus 0.0047 0.0147 0.0139
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0047 0.0147 1
Echinococcus granulosus phosphoglycerate mutase 0.0047 0.0147 0.0144
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0006
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.008 0.1221
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0047 0.0147 0.0144
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2806 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.2758 0.9831 0.9831
Onchocerca volvulus 0.001 0.0013 0.0005
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0013 0.0011
Echinococcus granulosus phosphoglycerate mutase 0.0047 0.0147 0.0144
Onchocerca volvulus 0.0047 0.0147 0.0139
Loa Loa (eye worm) hypothetical protein 0.1609 0.5723 0.572
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0026 0.1749
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0053 0.005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0045 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0318 0.0316
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0053 0.005
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0013 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0318 0.0316
Schistosoma mansoni microtubule-associated protein tau 0.0671 0.2376 0.2374
Brugia malayi tailless protein 0.001 0.0013 0.0084
Schistosoma mansoni lamin 0.0029 0.008 0.0078
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0188 0.0186
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0318 0.031
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.2758 0.9831 0.983
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0202 0.0194
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.0561 0.9303
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0202 0.02
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.1749
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0047 0.0147 0.769
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1197 0.4254 0.4239
Onchocerca volvulus 0.0028 0.0077 0.0069
Schistosoma mansoni dep domain containing protein 0.0009 0.0008 0.0006
Echinococcus granulosus ferritin 0.0008 0.0007 0.0005
Toxoplasma gondii phosphoglycerate mutase 0.0047 0.0147 0.7678
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0053 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0107 0.0082
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0027 0.0025
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.7295
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0188 0.0186
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0053 0.005
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0013 0.0005
Mycobacterium ulcerans hypothetical protein 0.0047 0.0147 0.0237
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0053 0.005
Onchocerca volvulus 0.001 0.0013 0.0005
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0053 0.0045
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0107 0.7295
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0017 0.0015
Onchocerca volvulus Protein UBASH3A homolog 0.0047 0.0147 0.0139
Onchocerca volvulus 0.0095 0.0315 0.0307
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0047 0.0147 1
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) hypothetical protein 0.0047 0.0147 0.0139
Mycobacterium ulcerans hypothetical protein 0.1656 0.5893 1
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.001 0.0013 0.0005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0013 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0017 0.0015
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1197 0.4254 0.4241
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0202 0.02
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0053 0.0753
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.1399 0.1397
Schistosoma mansoni lamin 0.0029 0.008 0.0078
Echinococcus multilocularis lamin 0.0029 0.008 0.0078
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Schistosoma mansoni hypothetical protein 0.0036 0.0106 0.0104
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0053 0.005
Brugia malayi TAR-binding protein 0.0063 0.0202 0.3271
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.0047 0.0147 0.0237
Schistosoma mansoni nuclear hormone receptor 0.001 0.0013 0.0011
Brugia malayi nuclear receptor RXR 0.0011 0.0017 0.0156
Schistosoma mansoni dishevelled 0.0009 0.0008 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0147 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0154 0.0152
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0053 0.0753
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0053 0.005
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0045 0.2072
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.1749
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0045 1
Leishmania major phosphoglycerate mutase protein, putative 0.0047 0.0147 0.0124
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0009 0.0008 0.0005
Mycobacterium ulcerans hydrolase MutT1 0.0047 0.0147 0.0237
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2758 0.9831 0.983
Schistosoma mansoni hypothetical protein 0.005 0.0154 0.0152
Brugia malayi hypothetical protein 0.0011 0.0017 0.0156
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0053 0.005
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0008 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0053 0.0753
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0156
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.3054
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0047 0.0147 0.769
Mycobacterium ulcerans phosphoglycerate mutase 0.0047 0.0147 0.0237
Schistosoma mansoni zinc finger protein 0.001 0.0013 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0053 0.005
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0013 0.0005
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.0603 0.0595
Brugia malayi hypothetical protein 0.001 0.0013 0.0084
Brugia malayi RNA binding protein 0.0063 0.0202 0.3271
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0017 0.0156
Schistosoma mansoni regulator of G protein signaling 0.0009 0.0008 0.0006
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.1749
Brugia malayi nuclear receptor RXR 0.001 0.0013 0.0084
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0053 0.005
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0015
Loa Loa (eye worm) intermediate filament protein 0.0029 0.008 0.0072
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0045 0.0019
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0047 0.0147 0.769
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0021
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.0561 0.0553
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.0142
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0013 0.0011
Trypanosoma brucei phosphoglycerate mutase, putative 0.0047 0.0147 0.0121
Toxoplasma gondii phosphoglycerate mutase family protein 0.0047 0.0147 0.7678
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0047 0.0147 0.0124
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Brugia malayi phosphoglycerate mutase family protein 0.0047 0.0147 0.2332
Onchocerca volvulus 0.0013 0.0023 0.0015
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0023 0.156
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0008 0.0006
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0009 0.0009 0.0623
Echinococcus multilocularis lamin dm0 0.0029 0.008 0.0078
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0021
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0023 0.156
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) hypothetical protein 0.0011 0.0017 0.0009
Brugia malayi intermediate filament protein 0.0029 0.008 0.1221
Schistosoma mansoni 6-phosphofructokinase 0.2806 1 1
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0009 0.0008 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.7295
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0047 0.0147 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0053 0.0753
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0053 0.0753
Brugia malayi ABC transporter family protein 0.0013 0.0023 0.0252
Schistosoma mansoni alpha-glucosidase 0.0141 0.048 0.0478
Brugia malayi UBASH3A protein homolog 0.0047 0.0147 0.2332
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0053 0.0753
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0106 0.0104
Brugia malayi hypothetical protein 0.001 0.0013 0.0084
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0013 0.0011
Onchocerca volvulus Protein UBASH3A homolog 0.0047 0.0147 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0053 0.0753
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0047 0.0147 0.0144
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0053 0.0045
Brugia malayi nuclear hormone receptor 0.0021 0.0053 0.0753
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0047 0.0147 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0053 0.0045
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0026 0.1749
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0013 0.0011
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0026 0.0017
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0047 0.0147 0.0121
Onchocerca volvulus Protein UBASH3A homolog 0.0047 0.0147 0.0139
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0188 0.0186
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0107 0.0099
Plasmodium falciparum phosphoglycerate mutase, putative 0.0047 0.0147 1
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0023 0.0021
Plasmodium falciparum phosphoglucomutase-2 0.0047 0.0147 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0053 0.0753
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0053 0.0045
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0047 0.0147 0.769
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.1771
Echinococcus granulosus expressed protein 0.0008 0.0007 0.0005
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.0047 0.0147 0.0237
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0026 0.0299
Onchocerca volvulus Protein UBASH3A homolog 0.0047 0.0147 0.0139
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.7295
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0021
Toxoplasma gondii phosphoglycerate mutase family protein 0.0047 0.0147 0.7678
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0026 0.1749
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0318 0.0316
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.1771
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0045 0.0064
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0047 0.0147 1
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0147 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0053 0.005
Echinococcus multilocularis microtubule associated protein 2 0.0671 0.2376 0.2374
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0053 0.005
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) phosphoglycerate mutase 0.0047 0.0147 0.0139
Brugia malayi nuclear receptor NHR-88 0.0021 0.0053 0.0753
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0053 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0318 0.0316
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0107 0.036 0.0352
Loa Loa (eye worm) hypothetical protein 0.0047 0.0147 0.0139
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Echinococcus multilocularis musashi 0.0029 0.008 0.0078
Schistosoma mansoni nuclear hormone receptor 0.001 0.0013 0.0011
Giardia lamblia Hypothetical protein 0.1656 0.5893 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.0143
Schistosoma mansoni hypothetical protein 0.0346 0.1214 0.1212
Schistosoma mansoni coup transcription factor 0.0021 0.0053 0.005
Schistosoma mansoni alpha glucosidase 0.0036 0.0107 0.0105
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.0561 0.0559
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0188 0.0308
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0047 0.0147 0.0121
Brugia malayi Latrophilin receptor protein 2 0.005 0.0154 0.2465
Echinococcus multilocularis regulator of G protein signaling 7 0.0009 0.0008 0.0006
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.036 0.592
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0107 0.0105
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0318 0.0316
Schistosoma mansoni hypothetical protein 0.0346 0.1214 0.1212
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0013 0.0011
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0188 0.0166
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0047 0.0147 0.0121
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.0142
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0023 0.156
Brugia malayi hypothetical protein 0.0009 0.0008 0.0005
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Echinococcus granulosus multidrug resistance protein 1 0.0009 0.0009 0.0007
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0147 1
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0047 0.0147 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0107 0.7295
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0045 0.2694
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0318 0.5215
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0053 0.005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0188 0.0308
Echinococcus multilocularis geminin 0.0346 0.1214 0.1212
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.0142
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0013 0.0011
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0023 0.156
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0047 0.0147 0.0121
Echinococcus multilocularis ATP binding cassette sub family B 0.0013 0.0022 0.002
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0008 0.0006
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0053 0.0753
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0013 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.7295
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0053 0.0045
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0053 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0053 0.0753
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0023 0.156
Echinococcus multilocularis ferritin 0.0008 0.0007 0.0005
Echinococcus granulosus cpg binding protein 0.003 0.0083 0.0081
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0154 0.0152
Echinococcus granulosus phosphoglycerate mutase 0.0047 0.0147 0.0144
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0053 0.005
Echinococcus multilocularis segment polarity protein dishevelled 0.0009 0.0008 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0202 0.3271
Schistosoma mansoni multidrug resistance protein 0.0013 0.0023 0.0021
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0188 1
Loa Loa (eye worm) hypothetical protein 0.2806 1 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0013 0.0023 0.156
Schistosoma mansoni hypothetical protein 0.005 0.0154 0.0152
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0154 0.0152
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0047 0.0147 1
Leishmania major phosphoglycerate mutase, putative 0.0047 0.0147 0.0124
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0033 0.0024
Echinococcus granulosus intermediate filament protein 0.0029 0.008 0.0078
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0013 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0013 0.0084
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0053 0.0753
Trichomonas vaginalis ABC transporter, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0017 0.0009
Echinococcus granulosus phosphoglycerate mutase 0.0047 0.0147 0.0144
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0053 0.0045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.008 0.0072
Schistosoma mansoni intermediate filament proteins 0.0029 0.008 0.0078
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0021
Echinococcus granulosus microtubule associated protein 2 0.0671 0.2376 0.2374
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0202 0.02
Schistosoma mansoni alpha-glucosidase 0.0141 0.048 0.0478
Onchocerca volvulus 0.0021 0.0053 0.0045
Schistosoma mansoni hypothetical protein 0.0107 0.036 0.0358
Loa Loa (eye worm) RNA binding protein 0.0063 0.0202 0.0194
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0045 0.0037
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0107 0.1665
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0013 0.0005
Schistosoma mansoni phosphoglycerate mutase 0.0047 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0107 0.7295
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Echinococcus granulosus dnaJ subfamily B 0.0398 0.1399 0.1397
Mycobacterium ulcerans lipoprotein LpqD 0.0047 0.0147 0.0237
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0021
Schistosoma mansoni apoferritin-2 0.0008 0.0007 0.0005
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Echinococcus granulosus regulator of G protein signaling 7 0.0009 0.0008 0.0006
Echinococcus granulosus GPCR family 2 0.005 0.0154 0.0152
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0047 0.0147 0.0121
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0107 0.0105
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0053 0.005
Giardia lamblia Hypothetical protein 0.1656 0.5893 1
Brugia malayi nuclear receptor NHR-67 0.001 0.0013 0.0084
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0047 0.0147 0.769
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2806 1 1
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0053 0.0753
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0026 0.0005
Schistosoma mansoni apoferritin-2 0.0008 0.0007 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0107 0.7295
Brugia malayi DIX domain containing protein 0.0009 0.0008 0.0005
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0053 0.005
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0154 0.2465
Echinococcus multilocularis multidrug resistance protein 1 0.0013 0.0023 0.0021
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0047 0.0147 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0053 0.005
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0014
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0043
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0106 0.0104
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1197 0.4254 0.4239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0045 0.0019
Schistosoma mansoni z-protein (S1r protein) 0.0009 0.0008 0.0006
Leishmania major hypothetical protein, unknown function 0.0047 0.0147 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0202 0.02
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0045 0.062
Trypanosoma brucei glucosidase, putative 0.0036 0.0107 0.0082
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0106 0.0104
Onchocerca volvulus 0.0047 0.0147 0.0139
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0175 0.0603 0.0595
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Mycobacterium ulcerans phosphoglycerate mutase 0.0047 0.0147 0.0237
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Mycobacterium leprae Possible phosphoglycerate mutase 0.0047 0.0147 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0154 0.0152
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0053 0.0045
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1656 0.5893 1
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0053 0.005
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0047 0.0147 0.0211
Schistosoma mansoni ferritin light chain 0.0008 0.0007 0.0005
Echinococcus granulosus Pleckstrin G protein interacting region 0.0009 0.0008 0.0006
Mycobacterium ulcerans phosphoglyceromutase 0.0047 0.0147 0.0237
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0045 0.0019
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Trichomonas vaginalis taga, putative 0.0013 0.0023 0.156
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.1749
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0053 0.005
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0107 0.0082
Mycobacterium ulcerans acid phosphatase 0.0047 0.0147 0.0237
Schistosoma mansoni smdr2 0.0013 0.0023 0.0021
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0053 0.0753
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0047 0.0147 0.0121
Mycobacterium tuberculosis Conserved protein 0.0047 0.0147 0.769
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Toxoplasma gondii phosphoglycerate mutase family protein 0.0047 0.0147 0.7678
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0013 0.0023 0.0021
Plasmodium vivax phosphoglycerate mutase, putative 0.0047 0.0147 1
Mycobacterium leprae conserved hypothetical protein 0.0047 0.0147 1
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0013 0.0023 0.0015
Toxoplasma gondii phosphoglycerate mutase family protein 0.0047 0.0147 0.7678
Loa Loa (eye worm) multidrug resistance protein 3 0.0013 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0047 0.0147 0.0139
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0147 0.769
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0053 0.0045
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0021
Trichomonas vaginalis ferritin, putative 0.0008 0.0007 0.0493
Brugia malayi Nuclear hormone receptor E75 0.001 0.0013 0.0084
Leishmania major glycerolphosphate mutase, putative 0.0047 0.0147 0.0124
Onchocerca volvulus 0.0029 0.008 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.008 0.0072
Echinococcus granulosus lamin 0.0029 0.008 0.0078
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0537 0.8897
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0047 0.0147 1
Brugia malayi hypothetical protein 0.0036 0.0106 0.1655
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0017 0.0015
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0047 0.0147 0.0121
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2806 1 1
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0047 0.0147 0.0121
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0107 0.5479
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0318 0.0316
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0047 0.0147 0.7678
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0033 0.0416
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.2806 1 1
Loa Loa (eye worm) DR-78 0.001 0.0013 0.0005
Plasmodium vivax phosphoglucomutase-2, putative 0.0047 0.0147 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0537 0.0529
Schistosoma mansoni ferritin 0.0008 0.0007 0.0005
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0013 0.0023 0.0816
Echinococcus granulosus tar DNA binding protein 0.0063 0.0202 0.02
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0043
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0026 0.0003
Schistosoma mansoni ferritin 0.0008 0.0007 0.0005
Leishmania major hypothetical protein, conserved 0.0047 0.0147 0.0124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0019
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0021
Brugia malayi hypothetical protein 0.0009 0.0008 0.0005
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0188 0.0308
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0026 0.1749
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0021
Echinococcus granulosus multidrug resistance protein 1 0.0009 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Schistosoma mansoni cpg binding protein 0.003 0.0083 0.0081
Brugia malayi N-terminal motif family protein 0.0175 0.0603 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0053 0.005
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0188 0.0186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0202 0.02
Echinococcus multilocularis GPCR, family 2 0.005 0.0154 0.0152
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0047 0.0147 0.0121
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0013 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0025 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0053 0.0045
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0107 0.7295
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2758 0.9831 0.983
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.007
Brugia malayi conserved hypotetical protein 0.001 0.0013 0.0084
Trypanosoma brucei glycerolphosphate mutase, putative 0.0047 0.0147 0.0121
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0047 0.0147 1
Leishmania major phosphoglycerate mutase family member 5, putative 0.0047 0.0147 0.0124
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0047 0.0147 0.0121
Treponema pallidum phosphoglyceromutase 0.0047 0.0147 1
Schistosoma mansoni cpg binding protein 0.0028 0.0077 0.0075
Schistosoma mansoni cpg binding protein 0.003 0.0083 0.0081
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0047 0.0147 0.0211
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0047 0.0147 0.0144
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0013 0.0023 0.0021
Echinococcus granulosus multidrug resistance protein 1 0.0013 0.0023 0.0021
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.0561 0.0559
Onchocerca volvulus 0.0029 0.008 0.0072
Schistosoma mansoni dishevelled 0.0009 0.0008 0.0006
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0013 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0077 0.0069
Leishmania major hypothetical protein, conserved 0.0047 0.0147 0.0124
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0053 0.005
Schistosoma mansoni ferritin 0.0008 0.0007 0.0005
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0047 0.0147 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0537 0.8897
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Schistosoma mansoni ferritin light chain 0.0008 0.0007 0.0005
Echinococcus multilocularis expressed protein 0.0008 0.0007 0.0005
Echinococcus granulosus segment polarity protein dishevelled 0.0009 0.0008 0.0006
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0013 0.0005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0045 0.0037
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0013 0.0023 0.156
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0013 0.0084
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0013 0.0023 0.156
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0318 0.0316
Brugia malayi phosphoglycerate mutase family protein 0.0047 0.0147 0.2332
Schistosoma mansoni nuclear receptor 0.001 0.0013 0.0011
Mycobacterium ulcerans hypothetical protein 0.0047 0.0147 0.0237
Trichomonas vaginalis abcb9, putative 0.0013 0.0023 0.156
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1656 0.5893 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0202 0.02
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0047 0.0147 0.769
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0047 0.0147 0.0144
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0188 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0154 0.0146
Schistosoma mansoni hypothetical protein 0.005 0.0154 0.0152
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0154 0.0146
Brugia malayi multidrug resistance protein 3 0.0013 0.0023 0.0252
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0047 0.0147 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0053 0.005
Brugia malayi steroid hormone receptor 0.0021 0.0053 0.0753
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0005
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0013 0.0011
Echinococcus granulosus lamin dm0 0.0029 0.008 0.0078
Brugia malayi nuclear hormone receptor 0.001 0.0013 0.0084
Echinococcus multilocularis phosphoglycerate mutase 0.0047 0.0147 0.0144
Trichomonas vaginalis abcb9, putative 0.0013 0.0023 0.156
Schistosoma mansoni hypothetical protein 0.0047 0.0147 0.0144
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0013 0.0023 0.156
Schistosoma mansoni phosphoglycerate mutase 0.0047 0.0147 0.0144
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0053 0.005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0053 0.005
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0047 0.0147 0.0211
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0013 0.0023 0.0863
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0047 0.0147 0.0121
Brugia malayi hypothetical protein 0.0011 0.0017 0.0156
Trichomonas vaginalis abcb9, putative 0.0013 0.0023 0.156
Loa Loa (eye worm) hypothetical protein 0.0021 0.0053 0.0045
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0107 0.0084
Entamoeba histolytica hypothetical protein 0.0036 0.0106 0.0142
Schistosoma mansoni hypothetical protein 0.005 0.0154 0.0152
Brugia malayi CXXC zinc finger family protein 0.0028 0.0077 0.1166
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0053 0.0753
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0013 0.0011

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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