Detailed information for compound 1776652

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 191.314 | Formula: C7H13NOS2
  • H donors: 1 H acceptors: 1 LogP: 2.85 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C=NCCCC[S+](CC)[O-]
  • InChi: 1S/C7H13NOS2/c1-2-11(9)6-4-3-5-8-7-10/h2-6H2,1H3
  • InChiKey: RJAHCEDKAOGQHF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) isocitrate dehydrogenase 0.002 0.002 0.002
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0012 0.0012
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.3185 0.983 0.983
Echinococcus multilocularis neuropeptide receptor A26 0.1173 0.3593 0.3593
Loa Loa (eye worm) hypothetical protein 0.1857 0.5715 0.5715
Trypanosoma brucei PAB1-binding protein , putative 0.0031 0.0053 0.0034
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0111 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0224 0.0224
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0048 0.0107 0.0107
Onchocerca volvulus 0.0091 0.0241 0.0115
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3185 0.983 0.983
Leishmania major phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0055 0.0127 0.0108
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0055 0.0127 0.5
Brugia malayi Isocitrate dehydrogenase 0.002 0.002 0.0147
Echinococcus multilocularis GPCR, family 2 0.005 0.0111 0.0111
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0055 0.0127 0.5
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0055 0.0127 0.5
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0055 0.0127 0.0174
Echinococcus granulosus neuropeptide s receptor 0.1173 0.3593 0.3593
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0055 0.0127 1
Schistosoma mansoni microsomal glutathione s-transferase 0.0506 0.1525 0.1525
Loa Loa (eye worm) hypothetical protein 0.0157 0.0443 0.0443
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0068 0.0068
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Echinococcus multilocularis neuropeptide s receptor 0.1173 0.3593 0.3593
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0055 0.0127 0.0108
Trypanosoma brucei phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Brugia malayi hypothetical protein 0.0091 0.0241 0.1816
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Brugia malayi jmjC domain containing protein 0.0036 0.0068 0.0512
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Schistosoma mansoni phosphoglycerate mutase 0.0055 0.0127 0.0127
Brugia malayi Angiotensin-converting enzyme family protein 0.0441 0.1326 1
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Brugia malayi MH2 domain containing protein 0.0074 0.0186 0.1399
Loa Loa (eye worm) hypothetical protein 0.0107 0.0289 0.0289
Mycobacterium leprae Possible phosphoglycerate mutase 0.0055 0.0127 0.5
Toxoplasma gondii LsmAD domain-containing protein 0.0031 0.0053 0.0223
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0289 0.2182
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Brugia malayi hypothetical protein 0.0022 0.0025 0.0189
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0012 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0068 0.0068
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0055 0.0127 0.0174
Brugia malayi UBASH3A protein homolog 0.0055 0.0127 0.096
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0068 0.0068
Mycobacterium tuberculosis Conserved protein 0.0055 0.0127 1
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Brugia malayi phosphoglycerate mutase family protein 0.0055 0.0127 0.096
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.2207 0.6798 0.6798
Loa Loa (eye worm) hypothetical protein 0.0037 0.0073 0.0073
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.324 1 1
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0055 0.0127 1
Schistosoma mansoni 6-phosphofructokinase 0.324 1 1
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Plasmodium vivax phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0012 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0224 0.0224
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Onchocerca volvulus 0.324 1 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni phosphoglycerate mutase 0.0055 0.0127 0.0127
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0443 0.334
Schistosoma mansoni hypothetical protein 0.0318 0.0944 0.0944
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0055 0.0127 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0036 0.0068 0.0068
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Brugia malayi Latrophilin receptor protein 2 0.005 0.0111 0.0839
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0119 0.0119
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.324 1 1
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0055 0.0127 1
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0119 0.0119
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0506 0.1525 0.1525
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0111 0.0111
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0022 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Brugia malayi jmjC domain containing protein 0.0036 0.0068 0.0512
Loa Loa (eye worm) hypothetical protein 0.3185 0.983 0.983
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Toxoplasma gondii MAPEG family protein 0.0506 0.1525 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0012 0.0012
Trypanosoma brucei glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0443 0.334
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0127 1
Schistosoma mansoni hypothetical protein 0.0318 0.0944 0.0944
Echinococcus granulosus geminin 0.0318 0.0944 0.0944
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0068 0.0068
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0098 0.7716
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0055 0.0127 0.5
Loa Loa (eye worm) hypothetical protein 0.0091 0.0241 0.0241
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Brugia malayi hypothetical protein 0.002 0.0019 0.0145
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0499 0.1505 0.1505
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Plasmodium vivax ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0012 0.0012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0086 0.0224 0.0224
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0048 0.0107 0.0807
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0053 0.0034
Leishmania major glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Treponema pallidum phosphoglyceromutase 0.0055 0.0127 0.5
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3185 0.983 0.983
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0048 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0111
Plasmodium vivax phosphoglucomutase-2, putative 0.0055 0.0127 1
Schistosoma mansoni transcription factor LCR-F1 0.0022 0.0025 0.0025
Leishmania major phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Mycobacterium tuberculosis Conserved protein 0.0055 0.0127 1
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0055 0.0127 0.5
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) phosphoglycerate mutase 0.0055 0.0127 0.0127
Brugia malayi hypothetical protein 0.0031 0.0053 0.04
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0111 0.0111
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1912 0.5884 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0068 0.0068
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0055 0.0127 1
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0055 0.0127 0.0174
Echinococcus granulosus microsomal glutathione S transferase 3 0.0506 0.1525 0.1525
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0055 0.0127 0.0715
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0022 0.0025 0.0025
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1912 0.5884 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0224 0.0224
Brugia malayi phosphoglycerate mutase family protein 0.0055 0.0127 0.096
Schistosoma mansoni hypothetical protein 0.0107 0.0289 0.0289
Brugia malayi isocitrate dehydrogenase 0.002 0.002 0.0147
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0243 0.0712 0.0712
Giardia lamblia Hypothetical protein 0.1912 0.5884 0.5
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0441 0.1326 0.1326
Loa Loa (eye worm) transcription factor SMAD2 0.0074 0.0186 0.0186
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0443 0.0443
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0111 0.0111
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Plasmodium falciparum phosphoglycerate mutase, putative 0.0055 0.0127 1
Leishmania major hypothetical protein, conserved 0.0031 0.0053 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0053 0.0034
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0012 0.0092
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.002 0.002 0.002
Leishmania major hypothetical protein, unknown function 0.0055 0.0127 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0111 0.0839
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0055 0.0127 1
Toxoplasma gondii phosphoglycerate mutase 0.0055 0.0127 0.0715
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0224 0.0224
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.002 0.002 0.002
Echinococcus granulosus neuropeptide receptor A26 0.1173 0.3593 0.3593
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0068 0.0068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0036 0.0068 0.0068
Echinococcus multilocularis geminin 0.0318 0.0944 0.0944
Loa Loa (eye worm) MH2 domain-containing protein 0.0074 0.0186 0.0186
Giardia lamblia Hypothetical protein 0.1912 0.5884 0.5
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Leishmania major phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0012 0.0012
Echinococcus multilocularis isocitrate dehydrogenase 0.002 0.002 0.002
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Mycobacterium ulcerans hypothetical protein 0.1912 0.5884 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0086 0.0224 0.1689
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0127 1
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3185 0.983 0.983
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Mycobacterium leprae probable isochorismate synthase EntC 0.0055 0.0127 0.5
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.0022 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0127 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0048 0.0107 0.0107
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0111 0.0111
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0243 0.0712 0.0592
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1382 0.4243 0.4232
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0098 0.7716
Brugia malayi N-terminal motif family protein 0.0243 0.0712 0.5365
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Plasmodium falciparum phosphoglucomutase-2 0.0055 0.0127 1
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Echinococcus granulosus GPCR family 2 0.005 0.0111 0.0111

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.85 uM Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay ChEMBL. 23685571

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23685571

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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