Detailed information for compound 1776655

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 205.341 | Formula: C8H15NOS2
  • H donors: 1 H acceptors: 1 LogP: 3.29 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: S=C=NCCCC[S+](C(C)C)[O-]
  • InChi: 1S/C8H15NOS2/c1-8(2)12(10)6-4-3-5-9-7-11/h8H,3-6H2,1-2H3
  • InChiKey: BAXOKRWCEZXWMX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0055 0.0127 0.5
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Toxoplasma gondii MAPEG family protein 0.0506 0.1525 1
Plasmodium vivax phosphoglucomutase-2, putative 0.0055 0.0127 1
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Brugia malayi Isocitrate dehydrogenase 0.002 0.002 0.0147
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0012 0.0012
Echinococcus granulosus GPCR family 2 0.005 0.0111 0.0111
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0048 0.0107 0.0807
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0055 0.0127 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0036 0.0068 0.0068
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Echinococcus multilocularis neuropeptide s receptor 0.1173 0.3593 0.3593
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Leishmania major phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0012 0.0012
Plasmodium falciparum phosphoglucomutase-2 0.0055 0.0127 1
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Trypanosoma brucei phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Brugia malayi UBASH3A protein homolog 0.0055 0.0127 0.096
Brugia malayi Angiotensin-converting enzyme family protein 0.0441 0.1326 1
Brugia malayi isocitrate dehydrogenase 0.002 0.002 0.0147
Schistosoma mansoni phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus multilocularis neuropeptide receptor A26 0.1173 0.3593 0.3593
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3185 0.983 0.983
Onchocerca volvulus 0.324 1 1
Schistosoma mansoni hypothetical protein 0.0318 0.0944 0.0944
Echinococcus multilocularis isocitrate dehydrogenase 0.002 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0111
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0055 0.0127 0.5
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Leishmania major glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.002 0.002 0.002
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0055 0.0127 0.0108
Brugia malayi latrophilin 2 splice variant baaae 0.0107 0.0289 0.2182
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0098 0.7716
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0012 0.0092
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0068 0.0068
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0053 0.0034
Schistosoma mansoni phosphoglycerate mutase 0.0055 0.0127 0.0127
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.2207 0.6798 0.6798
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Brugia malayi phosphoglycerate mutase family protein 0.0055 0.0127 0.096
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Plasmodium falciparum phosphoglycerate mutase, putative 0.0055 0.0127 1
Brugia malayi MH2 domain containing protein 0.0074 0.0186 0.1399
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0055 0.0127 0.5
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0086 0.0224 0.1689
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Loa Loa (eye worm) phosphoglycerate mutase 0.0055 0.0127 0.0127
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0055 0.0127 0.0174
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.002 0.002 0.002
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0012 0.0012
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0055 0.0127 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0068 0.0068
Echinococcus granulosus geminin 0.0318 0.0944 0.0944
Leishmania major phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Echinococcus granulosus microsomal glutathione S transferase 3 0.0506 0.1525 0.1525
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.005 0.0111 0.0111
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Schistosoma mansoni transcription factor LCR-F1 0.0022 0.0025 0.0025
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.0243 0.0712 0.0712
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0012 0.0012
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0012
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.3185 0.983 0.983
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0157 0.0443 0.0443
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0045 0.0098 0.7716
Mycobacterium tuberculosis Conserved protein 0.0055 0.0127 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0073 0.0073
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Brugia malayi N-terminal motif family protein 0.0243 0.0712 0.5365
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0022 0.0025 0.0025
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0086 0.0224 0.0224
Plasmodium vivax phosphoglycerate mutase, putative 0.0055 0.0127 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Loa Loa (eye worm) latrophilin receptor protein 2 0.005 0.0111 0.0111
Trypanosoma cruzi PAB1-binding protein , putative 0.0031 0.0053 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0127 1
Mycobacterium leprae probable isochorismate synthase EntC 0.0055 0.0127 0.5
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1382 0.4243 0.4232
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0055 0.0127 1
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0055 0.0127 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0499 0.1505 0.1505
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.005 0.0111 0.0111
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0048 0.0107 0.0107
Giardia lamblia Hypothetical protein 0.1912 0.5884 0.5
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0224 0.0224
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.3185 0.983 0.983
Trypanosoma brucei glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0055 0.0127 0.0127
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0022 0.0025 0.0025
Schistosoma mansoni microsomal glutathione s-transferase 0.0506 0.1525 0.1525
Mycobacterium leprae Possible phosphoglycerate mutase 0.0055 0.0127 0.5
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.005 0.0111 0.0111
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Plasmodium falciparum ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Plasmodium vivax ataxin-2 like protein, putative 0.0031 0.0053 0.3111
Treponema pallidum phosphoglyceromutase 0.0055 0.0127 0.5
Toxoplasma gondii LsmAD domain-containing protein 0.0031 0.0053 0.0223
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0068 0.0068
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0055 0.0127 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0157 0.0443 0.334
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0224 0.0224
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0048 0.0107 0.0107
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0068 0.0068
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Leishmania major hypothetical protein, unknown function 0.0055 0.0127 0.0108
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.0157 0.0443 0.0443
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.0053
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Brugia malayi hypothetical protein 0.002 0.0019 0.0145
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0055 0.0127 1
Leishmania major hypothetical protein, conserved 0.0031 0.0053 0.0034
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.324 1 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0224 0.0224
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0506 0.1525 0.1525
Echinococcus granulosus phosphoglycerate mutase 0.0055 0.0127 0.0127
Echinococcus granulosus neuropeptide receptor A26 0.1173 0.3593 0.3593
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.005 0.0111 0.0839
Loa Loa (eye worm) isocitrate dehydrogenase 0.002 0.002 0.002
Echinococcus multilocularis geminin 0.0318 0.0944 0.0944
Schistosoma mansoni 6-phosphofructokinase 0.324 1 1
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1912 0.5884 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0157 0.0443 0.334
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0224 0.0224
Echinococcus multilocularis GPCR, family 2 0.005 0.0111 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0127 1
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0119 0.0119
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Brugia malayi hypothetical protein 0.0091 0.0241 0.1816
Brugia malayi Latrophilin receptor protein 2 0.005 0.0111 0.0839
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.0127 1
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Toxoplasma gondii phosphoglycerate mutase 0.0055 0.0127 0.0715
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0048 0.0107 0.0107
Mycobacterium tuberculosis Conserved protein 0.0055 0.0127 1
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0055 0.0127 0.5
Schistosoma mansoni hypothetical protein 0.0022 0.0025 0.0025
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Schistosoma mansoni hypothetical protein 0.005 0.0111 0.0111
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0224 0.0224
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0055 0.0127 0.0174
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0055 0.0127 0.0108
Schistosoma mansoni hypothetical protein 0.0318 0.0944 0.0944
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0055 0.0127 1
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0012 0.0012
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0055 0.0127 0.0174
Loa Loa (eye worm) MH2 domain-containing protein 0.0074 0.0186 0.0186
Onchocerca volvulus 0.0091 0.0241 0.0115
Brugia malayi hypothetical protein 0.0022 0.0025 0.0189
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0441 0.1326 0.1326
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.3185 0.983 0.983
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.005 0.0111 0.0111
Leishmania major hypothetical protein, conserved 0.0055 0.0127 0.0108
Brugia malayi jmjC domain containing protein 0.0036 0.0068 0.0512
Loa Loa (eye worm) hypothetical protein 0.0107 0.0289 0.0289
Giardia lamblia Hypothetical protein 0.1912 0.5884 0.5
Loa Loa (eye worm) hypothetical protein 0.0091 0.0241 0.0241
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0243 0.0712 0.0592
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0055 0.0127 0.5
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0055 0.0127 0.0108
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Schistosoma mansoni voltage-gated potassium channel 0.0052 0.0119 0.0119
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.324 1 1
Brugia malayi jmjC domain containing protein 0.0036 0.0068 0.0512
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Echinococcus granulosus neuropeptide s receptor 0.1173 0.3593 0.3593
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1912 0.5884 1
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.3185 0.983 0.983
Leishmania major phosphoglycerate mutase, putative 0.0055 0.0127 0.0108
Schistosoma mansoni hypothetical protein 0.0107 0.0289 0.0289
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) transcription factor SMAD2 0.0074 0.0186 0.0186
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0012 0.0012
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.324 1 1
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0055 0.0127 0.0108
Mycobacterium leprae conserved hypothetical protein 0.0055 0.0127 0.5
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0127
Brugia malayi hypothetical protein 0.0031 0.0053 0.04
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0055 0.0127 0.0108
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.002 0.002 0.002
Toxoplasma gondii phosphoglycerate mutase family protein 0.0055 0.0127 0.0715
Mycobacterium ulcerans hypothetical protein 0.1912 0.5884 1
Trypanosoma brucei PAB1-binding protein , putative 0.0031 0.0053 0.0034
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1382 0.4243 0.4232
Echinococcus multilocularis phosphoglycerate mutase 0.0055 0.0127 0.0127
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0055 0.0127 0.0715
Brugia malayi phosphoglycerate mutase family protein 0.0055 0.0127 0.096
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Loa Loa (eye worm) hypothetical protein 0.1857 0.5715 0.5715
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0036 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0055 0.0127 0.0108
Loa Loa (eye worm) hypothetical protein 0.0055 0.0127 0.0127

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 3.74 uM Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay ChEMBL. 23685571

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 23685571

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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