Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0071 | 0.5 |
Onchocerca volvulus | 0.0204 | 0.162 | 0.5 | |
Echinococcus multilocularis | neuroligin | 0.0204 | 0.162 | 0.162 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0204 | 0.162 | 0.1581 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0204 | 0.162 | 0.162 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0204 | 0.162 | 0.162 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Loa Loa (eye worm) | carboxylesterase | 0.1206 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Echinococcus granulosus | neuroligin | 0.0204 | 0.162 | 0.162 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.162 | 0.162 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0071 | 0.0071 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0204 | 0.162 | 0.1581 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1206 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1206 | 1 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0046 | 0.0046 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0204 | 0.162 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0071 | 0.5 |
Onchocerca volvulus | 0.0204 | 0.162 | 0.5 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0204 | 0.162 | 0.1581 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0046 | 0.0046 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0071 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0046 | 0.0046 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.162 | 0.162 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0071 | 0.0025 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0071 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0197 | 0.0151 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0071 | 0.0071 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0326 | 0.0326 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0204 | 0.162 | 0.1581 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1206 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0204 | 0.162 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.162 | 0.162 |
Onchocerca volvulus | 0.0204 | 0.162 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0326 | 0.0326 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0197 | 0.0197 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0071 | 0.0025 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0071 | 0.0071 |
Onchocerca volvulus | 0.0204 | 0.162 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0204 | 0.162 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1206 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0204 | 0.162 | 0.162 |
Schistosoma mansoni | gliotactin | 0.0204 | 0.162 | 0.1581 |
Echinococcus multilocularis | acetylcholinesterase | 0.1206 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0204 | 0.162 | 0.162 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0071 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1206 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1206 | 1 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0071 | 0.5 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0071 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0326 | 0.0326 |
Loa Loa (eye worm) | carboxylesterase | 0.0204 | 0.162 | 0.162 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0204 | 0.162 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0071 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0323 | 0.2613 | 0.2613 |
Echinococcus multilocularis | ankyrin repeat protein | 0.0313 | 0.2533 | 0.2533 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | carboxylesterase | 0.0204 | 0.162 | 0.162 |
Schistosoma mansoni | acetylcholinesterase | 0.0204 | 0.162 | 0.1581 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0046 | 0.0046 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.1206 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0204 | 0.162 | 0.162 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0204 | 0.162 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0204 | 0.162 | 0.1581 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0326 | 0.0326 |
Brugia malayi | Carboxylesterase family protein | 0.1206 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0323 | 0.2617 | 0.2617 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0071 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1206 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Echinococcus granulosus | acetylcholinesterase | 0.1206 | 1 | 1 |
Onchocerca volvulus | 0.0204 | 0.162 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0204 | 0.162 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.162 | 0.162 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0046 | 0.0046 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0204 | 0.162 | 0.162 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0071 | 0.5 |
Schistosoma mansoni | transient receptor potential cation channel subfamily A member | 0.0313 | 0.2533 | 0.2498 |
Echinococcus granulosus | ankyrin repeat protein | 0.0313 | 0.2533 | 0.2533 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0071 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0204 | 0.162 | 0.162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.