Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | SRC-1 | 0.0972 | 0 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.4311 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0972 | 0 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2544 | 0.4708 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.4238 | 0.9782 | 0.9706 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.2544 | 0.4708 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.2544 | 0.4708 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.4311 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.4238 | 0.9782 | 0.9706 |
Loa Loa (eye worm) | hypothetical protein | 0.4311 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2472 | 0.4491 | 0.4491 |
Brugia malayi | Protein kinase domain containing protein | 0.0972 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.4238 | 0.9782 | 0.9706 |
Brugia malayi | protein-tyrosine kinase | 0.0972 | 0 | 0.5 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.2544 | 0.4708 | 1 |
Onchocerca volvulus | 0.4311 | 1 | 1 | |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.4238 | 0.9782 | 0.9706 |
Brugia malayi | Protein kinase domain containing protein | 0.0972 | 0 | 0.5 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0972 | 0 | 0.5 |
Brugia malayi | SH2 domain containing protein | 0.0972 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0972 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.4311 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0972 | 0 | 0.5 |
Brugia malayi | SH2 domain containing protein | 0.0972 | 0 | 0.5 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.4311 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.2544 | 0.4708 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0972 | 0 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.4311 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.4238 | 0.9782 | 0.9782 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.4311 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.