Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0031 | 0.0556 | 0.0571 |
Plasmodium falciparum | glutathione reductase | 0.0118 | 0.2656 | 0.3214 |
Trypanosoma brucei | trypanothione reductase | 0.0339 | 0.8047 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0118 | 0.2656 | 0.3214 |
Mycobacterium ulcerans | hypothetical protein | 0.0031 | 0.0556 | 0.108 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0556 | 0.0556 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0102 | 0.0102 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Onchocerca volvulus | Peroxidase homolog | 0.0042 | 0.081 | 0.7878 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0031 | 0.0556 | 0.0571 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0118 | 0.2656 | 0.6078 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0031 | 0.0556 | 0.0571 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0118 | 0.2656 | 0.3214 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.1077 | 0.1339 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0672 | 0.0835 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0019 | 0.0019 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0031 | 0.0556 | 0.0571 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0672 | 0.0835 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0086 | 0.1897 | 0.2358 |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0031 | 0.0556 | 0.108 |
Brugia malayi | Animal haem peroxidase family protein | 0.0042 | 0.081 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.1317 | 0.1317 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0031 | 0.0556 | 0.108 |
Brugia malayi | Thioredoxin reductase | 0.0339 | 0.8047 | 1 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | oxidoreductase | 0.0013 | 0.0102 | 0.0127 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0017 | 0.02 | 0.02 |
Onchocerca volvulus | Peroxidasin homolog | 0.0042 | 0.081 | 0.7878 |
Echinococcus granulosus | peroxidasin | 0.0042 | 0.081 | 0.081 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Plasmodium falciparum | thioredoxin reductase | 0.0118 | 0.2656 | 0.3214 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | glutathione reductase | 0.0339 | 0.8047 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0243 | 0.5696 | 0.5696 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0118 | 0.2656 | 0.6078 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.1312 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0013 | 0.0102 | 0.0127 |
Brugia malayi | Animal haem peroxidase family protein | 0.0042 | 0.081 | 0.1006 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0556 | 0.0691 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Echinococcus granulosus | geminin | 0.0179 | 0.4148 | 0.4148 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0031 | 0.0556 | 0.108 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0185 | 0.4303 | 0.5288 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.02 | 0.0248 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.1348 | 0.1675 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0031 | 0.0556 | 0.0571 |
Onchocerca volvulus | 0.0042 | 0.081 | 0.7878 | |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0018 | 0.0241 | 0.0241 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0031 | 0.0556 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0118 | 0.2656 | 0.5604 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0017 | 0.02 | 0.0123 |
Onchocerca volvulus | 0.0031 | 0.0556 | 0.5052 | |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0118 | 0.2656 | 0.3214 |
Onchocerca volvulus | Peroxidase homolog | 0.0042 | 0.081 | 0.7878 |
Schistosoma mansoni | sulfide quinone reductase | 0.0031 | 0.0556 | 0.0556 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0185 | 0.4303 | 1 |
Onchocerca volvulus | 0.0042 | 0.081 | 0.7878 | |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.02 | 0.0248 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0202 | 0.0251 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0118 | 0.2656 | 0.6078 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0202 | 0.0202 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0202 | 0.0202 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.2656 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0031 | 0.0556 | 0.0691 |
Leishmania major | trypanothione reductase | 0.0339 | 0.8047 | 1 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0031 | 0.0556 | 0.0571 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.3214 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0031 | 0.0556 | 0.0571 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0118 | 0.2656 | 0.5604 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0123 | 0.2775 | 0.3449 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0031 | 0.0556 | 0.0556 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0064 | 0.1348 | 0.1348 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0064 | 0.1348 | 0.1348 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Toxoplasma gondii | thioredoxin reductase | 0.0339 | 0.8047 | 1 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0031 | 0.0556 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0102 | 0.0127 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0031 | 0.0556 | 1 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0031 | 0.0556 | 0.0691 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0118 | 0.2656 | 0.6078 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0031 | 0.0556 | 0.108 |
Chlamydia trachomatis | thioredoxin reductase | 0.0031 | 0.0556 | 0.108 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0672 | 0.0672 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0202 | 0.0202 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0031 | 0.0556 | 0.0556 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0118 | 0.2656 | 0.3214 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0031 | 0.0556 | 0.0556 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0118 | 0.2656 | 0.3214 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Onchocerca volvulus | Dual oxidase homolog | 0.0042 | 0.081 | 0.7878 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0513 | 0.0638 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.1 | 0.1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0202 | 0.0202 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.1312 |
Trypanosoma brucei | NADH dehydrogenase | 0.0031 | 0.0556 | 0.0571 |
Trichomonas vaginalis | hypothetical protein | 0.0185 | 0.4303 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0185 | 0.4303 | 1 |
Onchocerca volvulus | 0.0029 | 0.0513 | 0.4579 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0013 | 0.0102 | 0.0102 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | Blistered cuticle protein 3 | 0.0042 | 0.081 | 0.1006 |
Brugia malayi | Animal haem peroxidase family protein | 0.0042 | 0.081 | 0.1006 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.02 | 0.0248 |
Schistosoma mansoni | P2X receptor subunit | 0.0066 | 0.1391 | 0.1391 |
Schistosoma mansoni | jumonji domain containing protein | 0.0062 | 0.1307 | 0.1307 |
Brugia malayi | jmjC domain containing protein | 0.0064 | 0.1348 | 0.1675 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0017 | 0.02 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0202 | 0.0251 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0017 | 0.02 | 0.0123 |
Plasmodium falciparum | thioredoxin reductase | 0.0339 | 0.8047 | 1 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0031 | 0.0556 | 0.108 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.2656 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Echinococcus multilocularis | peroxidasin | 0.0042 | 0.081 | 0.081 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0118 | 0.2656 | 0.3214 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0339 | 0.8047 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0042 | 0.081 | 0.1006 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0031 | 0.0556 | 0.0571 |
Plasmodium vivax | glutathione reductase, putative | 0.0339 | 0.8047 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0031 | 0.0556 | 0.108 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0118 | 0.2656 | 0.3214 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1077 | 0.1339 |
Mycobacterium ulcerans | dehydrogenase | 0.0031 | 0.0556 | 0.108 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0031 | 0.0556 | 0.0556 |
Echinococcus multilocularis | dnaJ subfamily B | 0.042 | 1 | 1 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0013 | 0.0102 | 0.0102 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0556 | 0.0556 |
Mycobacterium tuberculosis | Probable reductase | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.02 | 0.0248 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0243 | 0.5696 | 0.5696 |
Echinococcus multilocularis | phd:f box containing protein | 0.0017 | 0.02 | 0.02 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0042 | 0.081 | 0.1006 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0017 | 0.02 | 0.02 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.1522 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0031 | 0.0556 | 0.0571 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0031 | 0.0556 | 0.108 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0019 | 0.0023 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0185 | 0.4303 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.2879 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.1077 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.5696 | 0.7078 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0031 | 0.0556 | 0.0556 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0118 | 0.2656 | 0.3214 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.6078 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.02 | 0.0248 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0062 | 0.1307 | 0.1307 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0202 | 0.0202 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0031 | 0.0556 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.1312 | 0.1312 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0031 | 0.0556 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0185 | 0.4303 | 0.5288 |
Schistosoma mansoni | sulfide quinone reductase | 0.0031 | 0.0556 | 0.0556 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0031 | 0.0556 | 0.108 |
Plasmodium vivax | JmjC domain containing protein | 0.0017 | 0.02 | 0.0123 |
Mycobacterium ulcerans | monoxygenase | 0.0031 | 0.0556 | 0.108 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0031 | 0.0556 | 0.0571 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.4631 | 0.4631 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0031 | 0.0556 | 0.108 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.02 | 0.0248 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0185 | 0.4303 | 0.5288 |
Schistosoma mansoni | protein phosphatase 2C | 0.0017 | 0.02 | 0.02 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0202 | 0.0202 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.1312 | 0.1522 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.1 | 0.1 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.02 | 0.0123 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Schistosoma mansoni | peroxidasin | 0.0042 | 0.081 | 0.081 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0554 | 0.0554 |
Brugia malayi | glutathione reductase | 0.0339 | 0.8047 | 1 |
Wolbachia endosymbiont of Brugia malayi | NADPH-dependent glutamate synthase beta chain | 0.0031 | 0.0556 | 0.108 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0013 | 0.0102 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0554 | 0.0554 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0017 | 0.02 | 0.02 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0031 | 0.0556 | 0.108 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0019 | 0.0019 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.4631 | 0.4631 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0031 | 0.0556 | 0.0691 |
Plasmodium falciparum | glutathione reductase | 0.0339 | 0.8047 | 1 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0031 | 0.0556 | 0.0571 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0031 | 0.0556 | 0.108 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0031 | 0.0556 | 0.108 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0118 | 0.2656 | 0.6078 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | hypothetical protein | 0.042 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Toxoplasma gondii | selenide, water dikinase | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0086 | 0.1897 | 0.2358 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0031 | 0.0556 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.2656 |
Treponema pallidum | NADH oxidase | 0.0118 | 0.2656 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0118 | 0.2656 | 0.3214 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0017 | 0.02 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0031 | 0.0556 | 0.0571 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0062 | 0.1307 | 0.1307 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0513 | 0.0513 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.1522 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0031 | 0.0556 | 0.0571 |
Onchocerca volvulus | 0.005 | 0.1 | 1 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.2879 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.02 | 0.0248 |
Schistosoma mansoni | peroxidasin | 0.0042 | 0.081 | 0.081 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.02 | 0.0123 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0017 | 0.02 | 0.02 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0031 | 0.0556 | 0.108 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0017 | 0.02 | 0.02 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0031 | 0.0556 | 0.108 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0013 | 0.0102 | 0.0127 |
Brugia malayi | Animal haem peroxidase family protein | 0.0042 | 0.081 | 0.1006 |
Brugia malayi | Peroxidasin | 0.0042 | 0.081 | 0.1006 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0339 | 0.8047 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0066 | 0.1391 | 0.1391 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.02 | 0.0248 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0031 | 0.0556 | 0.0571 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0556 | 0.0556 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0123 | 0.2775 | 0.3449 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0339 | 0.8047 | 0.8047 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0118 | 0.2656 | 0.3214 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | MH2 domain containing protein | 0.0123 | 0.2775 | 0.3449 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0064 | 0.1348 | 0.1348 |
Brugia malayi | glutamate synthase | 0.0031 | 0.0556 | 0.0691 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0031 | 0.0556 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0118 | 0.2656 | 0.3301 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.1312 | 0.1312 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0118 | 0.2656 | 0.3214 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.02 | 0.0248 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0554 | 0.0554 |
Onchocerca volvulus | Peroxidasin homolog | 0.0042 | 0.081 | 0.7878 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.4148 | 0.4148 |
Echinococcus granulosus | glutamate synthase | 0.0031 | 0.0556 | 0.0556 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0513 | 0.0638 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0339 | 0.8047 | 1 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0018 | 0.0241 | 0.0241 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0556 | 0.0556 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0042 | 0.081 | 0.1006 |
Brugia malayi | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0556 | 0.0571 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0031 | 0.0556 | 0.0691 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0339 | 0.8047 | 0.8047 |
Echinococcus multilocularis | geminin | 0.0179 | 0.4148 | 0.4148 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.081 | 0.1006 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0339 | 0.8047 | 1 |
Brugia malayi | hypothetical protein | 0.0243 | 0.5696 | 0.7078 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0031 | 0.0556 | 0.0571 |
Schistosoma mansoni | phd/f-box containing protein | 0.0017 | 0.02 | 0.02 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0031 | 0.0556 | 0.108 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0031 | 0.0556 | 0.0571 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0185 | 0.4303 | 0.5288 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0031 | 0.0556 | 0.0571 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0031 | 0.0556 | 0.0571 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0031 | 0.0556 | 0.0571 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Echinococcus granulosus | phd:f box containing protein | 0.0017 | 0.02 | 0.02 |
Brugia malayi | Animal haem peroxidase family protein | 0.0042 | 0.081 | 0.1006 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0118 | 0.2656 | 0.6078 |
Leishmania major | NADH dehydrogenase, putative | 0.0031 | 0.0556 | 0.0571 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0031 | 0.0556 | 0.0556 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0118 | 0.2656 | 0.3214 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0031 | 0.0556 | 0.0556 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.4631 | 0.4631 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.02 | 0.0248 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0062 | 0.1307 | 0.1307 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0031 | 0.0556 | 0.0571 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0017 | 0.02 | 0.02 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.1 | 0.1243 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0185 | 0.4303 | 1 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.1077 | 0.1339 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0031 | 0.0556 | 0.0571 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Brugia malayi | jmjC domain containing protein | 0.0062 | 0.1307 | 0.1625 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0102 | 0.0127 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0554 | 0.0554 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0202 | 0.0251 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0031 | 0.0556 | 0.108 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.4148 | 0.4148 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0042 | 0.081 | 0.1006 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0017 | 0.02 | 0.0123 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0031 | 0.0556 | 0.108 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0031 | 0.0556 | 0.0571 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0042 | 0.081 | 0.7878 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0042 | 0.081 | 0.1006 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0118 | 0.2656 | 1 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0031 | 0.0556 | 0.0571 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0031 | 0.0556 | 0.0691 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0202 | 0.0251 |
Onchocerca volvulus | 0.0042 | 0.081 | 0.7878 | |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.1154 | 0.1324 |
Echinococcus multilocularis | glutamate synthase | 0.0031 | 0.0556 | 0.0556 |
Schistosoma mansoni | dihydropteridine reductase | 0.0013 | 0.0102 | 0.0102 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0017 | 0.02 | 0.02 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0118 | 0.2656 | 0.3214 |
Schistosoma mansoni | jumonji domain containing protein | 0.0017 | 0.02 | 0.02 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0118 | 0.2656 | 0.3214 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0016 | 0.002 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.02 | 0.0123 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0031 | 0.0556 | 0.0571 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0062 | 0.1312 | 0.2879 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.