Detailed information for compound 1780514

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 433.566 | Formula: C25H27N3O2S
  • H donors: 2 H acceptors: 2 LogP: 4.47 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(Cc1ccc(cc1)c1ccc(s1)C(=O)Nc1cc(ccc1C)C(=O)NC1CC1)C
  • InChi: 1S/C25H27N3O2S/c1-16-4-7-19(24(29)26-20-10-11-20)14-21(16)27-25(30)23-13-12-22(31-23)18-8-5-17(6-9-18)15-28(2)3/h4-9,12-14,20H,10-11,15H2,1-3H3,(H,26,29)(H,27,30)
  • InChiKey: UMOQDMLDLKTMII-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens mitogen-activated protein kinase 11 Starlite/ChEMBL References
Homo sapiens mitogen-activated protein kinase 14 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Schistosoma japonicum ko:K04441 p38 MAP kinase, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Brugia malayi P38 map kinase family protein 2 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma congolense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma brucei gambiense mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania infantum mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania donovani mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Trypanosoma cruzi mitogen-activated protein kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 11 Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania mexicana mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Candida albicans MAP kinase involved in osmoregulation Get druggable targets OG5_128610 All targets in OG5_128610
Leishmania braziliensis mitogen-activated protein kinase 3, putative,map kinase 3, putative Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus multilocularis mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
Echinococcus granulosus mitogen activated protein kinase 14 Get druggable targets OG5_128610 All targets in OG5_128610
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 14 360 aa 336 aa 33.3 %
Trypanosoma brucei mitogen-activated protein kinase 5 mitogen-activated protein kinase 11 364 aa 361 aa 33.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0054 0.0054
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0094 0.0461
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Schistosoma mansoni septate junction protein 0.0025 0.0095 0.0093
Schistosoma mansoni amine GPCR 0.0018 0.0043 0.0041
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0161 0.1102 0.2689
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0147 0.0359
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0101 0.0246
Brugia malayi jmjC domain containing protein 0.0093 0.0596 0.1452
Loa Loa (eye worm) thymidylate synthase 0.0562 0.4092 1
Schistosoma mansoni pyruvate kinase 0.0032 0.0147 0.0145
Schistosoma mansoni hypothetical protein 0.0028 0.0117 0.0114
Plasmodium vivax SET domain protein, putative 0.0035 0.0165 0.0402
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Toxoplasma gondii pyruvate kinase PyK1 0.0032 0.0147 0.036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0054 0.0126
Brugia malayi valosin containing protein 0.0016 0.0029 0.0065
Onchocerca volvulus 0.0075 0.0464 0.1129
Echinococcus multilocularis endoplasmin 0.0025 0.0093 0.0093
Onchocerca volvulus 0.0018 0.0043 0.01
Echinococcus multilocularis dnaJ subfamily B 0.0804 0.5889 0.5889
Loa Loa (eye worm) hypothetical protein 0.0304 0.2168 0.5299
Echinococcus multilocularis pyruvate kinase 0.0017 0.003 0.003
Mycobacterium ulcerans hypothetical protein 0.0035 0.0166 0.0332
Giardia lamblia DINP protein human, muc B family 0.0037 0.0185 0.078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0147 0.0354
Plasmodium falciparum flap endonuclease 1 0.0025 0.0094 0.0229
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0043 0.0041
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0018 0.0043 0.0041
Onchocerca volvulus Neurogenic locus notch homolog 0.0025 0.0095 0.0227
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.2181 0.2181
Brugia malayi ecdysteroid receptor 0.002 0.0054 0.0126
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0185 0.0452
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0053 0.0297 0.0726
Leishmania major hypothetical protein, conserved 0.0024 0.0088 0.0216
Echinococcus multilocularis protein jagged 1 0.0025 0.0095 0.0095
Trypanosoma cruzi Heat shock protein 83, putative 0.0032 0.0141 0.0339
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0043 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0166 0.0164
Brugia malayi Carboxylesterase family protein 0.0444 0.3209 0.7841
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Loa Loa (eye worm) endoplasmin 0.0032 0.0141 0.0344
Brugia malayi Cadherin domain containing protein 0.0025 0.0095 0.0227
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0025 0.0095 0.0093
Echinococcus granulosus acetylcholinesterase 0.0444 0.3209 0.3209
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0166 0.0332
Leishmania major DNA polymerase eta, putative 0.0062 0.0369 0.0902
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0054 0.0052
Trypanosoma brucei pyruvate kinase 1 0.0032 0.0147 0.0354
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis lipoxygenase domain containing protein 0.0238 0.1677 0.1677
Echinococcus granulosus neural cadherin 0.0025 0.0095 0.0095
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0074 0.0181
Schistosoma mansoni hypothetical protein 0.0018 0.0043 0.0041
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0145 0.035
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0088 0.0216
Brugia malayi Blistered cuticle protein 3 0.0079 0.0491 0.1194
Onchocerca volvulus Huntingtin homolog 0.0119 0.0791 0.1929
Toxoplasma gondii heat shock protein HSP90 0.0032 0.0141 0.0344
Schistosoma mansoni DNA polymerase eta 0.0062 0.0369 0.0367
Brugia malayi putative neuropeptide receptor 0.0018 0.0043 0.01
Echinococcus granulosus peptide allatostatin:somatostatin 0.0018 0.0043 0.0043
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0094 0.023
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0033 0.0152 0.015
Echinococcus granulosus cpg binding protein 0.006 0.035 0.035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0054 0.0126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Brugia malayi Delta serrate ligand family protein 0.0025 0.0095 0.0227
Echinococcus granulosus BC026374 protein S09 family 0.0075 0.0464 0.0464
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0043 0.0043
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0054 0.0054
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0166 0.0332
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.002 0.0043
Schistosoma mansoni flap endonuclease-1 0.0023 0.0076 0.0074
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0165 0.0165
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0075 0.0464 0.0464
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0054 0.0126
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0042 0.0183
Onchocerca volvulus 0.0018 0.0043 0.01
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Schistosoma mansoni survival motor neuron protein 0.0047 0.0255 0.0252
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0043 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0166 0.0164
Echinococcus multilocularis GPCR, family 2 0.0015 0.002 0.002
Echinococcus granulosus g-protein coupled receptor 0.0018 0.0043 0.0043
Brugia malayi Peroxidasin 0.0079 0.0491 0.1194
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.2018 0.9306
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0166 0.0332
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0169 0.1162 0.1162
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0321 0.032
Brugia malayi Bromodomain containing protein 0.0172 0.1186 0.2894
Echinococcus granulosus acetylcholinesterase 0.0444 0.3209 0.3209
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1615 0.1615
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Brugia malayi jmjC domain containing protein 0.0037 0.0185 0.0447
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus neuropeptide receptor 0.0018 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0054 0.0052
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0471 0.3408 0.8328
Schistosoma mansoni protein kinase 0.0171 0.1182 0.118
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0093 0.0455
Echinococcus multilocularis lamin 0.0026 0.0101 0.0101
Onchocerca volvulus 0.0056 0.0326 0.0792
Echinococcus multilocularis heat shock protein 0.0032 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.005 0.0278 0.0678
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0054 0.0126
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Leishmania major mitochondrial DNA polymerase beta 0.0293 0.2088 0.5104
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0042 0.0101
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0095 0.0095
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Giardia lamblia Heat shock protein HSP 90-alpha 0.0032 0.0141 0.0559
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0266 0.0651
Echinococcus granulosus neuropeptides capa receptor 0.0018 0.0043 0.0043
Brugia malayi GnHR receptor homolog 0.0018 0.0043 0.01
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0141 0.0339
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 0.409
Onchocerca volvulus 0.0018 0.0043 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0054 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni slit 0.0025 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Echinococcus granulosus thymidylate synthase 0.0562 0.4092 0.4092
Schistosoma mansoni pyruvate kinase 0.0017 0.003 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0054 0.0126
Onchocerca volvulus 0.0025 0.0095 0.0227
Schistosoma mansoni lamin 0.0026 0.0101 0.0099
Loa Loa (eye worm) hypothetical protein 0.0169 0.1162 0.284
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0053 0.0297 0.0297
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0054 0.0131
Schistosoma mansoni opsin-like receptor 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Entamoeba histolytica cdc48-like protein, putative 0.0027 0.0105 0.0472
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0161 0.1102 0.1102
Echinococcus granulosus GPCR family 2 0.0015 0.002 0.002
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0054 0.0052
Echinococcus multilocularis allatostatin A receptor 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Onchocerca volvulus 0.0018 0.0043 0.01
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.005 0.0278 0.0673
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Loa Loa (eye worm) acetylcholinesterase 1 0.0444 0.3209 0.7842
Echinococcus multilocularis pyruvate kinase 0.0017 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0562 0.4092 1
Echinococcus granulosus heat shock protein 0.0032 0.0141 0.0141
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0166 0.0401
Brugia malayi Carboxylesterase family protein 0.0075 0.0464 0.1129
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.0938 0.2112
Echinococcus granulosus dna polymerase eta 0.0062 0.0369 0.0369
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0321 0.032
Loa Loa (eye worm) hypothetical protein 0.0032 0.0147 0.0359
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Echinococcus granulosus Polycystic kidney disease protein 0.0238 0.1677 0.1677
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0185 0.0183
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0939 0.229
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0053 0.0052
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0161 0.1102 0.2693
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0054 0.0052
Onchocerca volvulus 0.0075 0.0464 0.1129
Trichomonas vaginalis spcc417.12 protein, putative 0.0075 0.0464 0.2295
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0042 0.0042
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0238 0.1677 0.4099
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0185 0.0185
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0018 0.0043 0.0043
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0093 0.0455
Brugia malayi CXXC zinc finger family protein 0.0056 0.0326 0.0792
Onchocerca volvulus 0.0018 0.0043 0.01
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0043 0.0041
Schistosoma mansoni alpha-1 adrenergic receptor 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Mycobacterium tuberculosis Conserved protein 0.0035 0.0166 0.0332
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni sphingosine kinase A B 0.0304 0.2168 0.2167
Onchocerca volvulus 0.0035 0.0165 0.0398
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0028 0.0115 0.0113
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0042 0.0101
Plasmodium vivax endoplasmin, putative 0.0032 0.0141 0.0343
Echinococcus granulosus protein jagged 1 0.0025 0.0095 0.0095
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0054 0.0126
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0199 0.0199
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0098 0.0235
Brugia malayi beta-lactamase 0.0035 0.0166 0.0401
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0185 0.0452
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0454 0.0452
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0141 0.0339
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0596 0.0596
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0321 0.0784
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Brugia malayi G protein-coupled receptor F59B2.13 0.0018 0.0043 0.01
Echinococcus multilocularis pyruvate kinase 0.0017 0.003 0.003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0444 0.3209 0.3207
Loa Loa (eye worm) animal heme peroxidase 0.0079 0.0491 0.1199
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0025 0.0093 0.0093
Echinococcus granulosus g protein coupled receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Onchocerca volvulus 0.0238 0.1677 0.4095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Onchocerca volvulus 0.0018 0.0043 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Schistosoma mansoni intermediate filament proteins 0.0026 0.0101 0.0099
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.2181 0.2181
Echinococcus granulosus pyruvate kinase 0.0017 0.003 0.003
Onchocerca volvulus 0.0026 0.0101 0.0241
Schistosoma mansoni protein kinase 0.0053 0.0297 0.0295
Schistosoma mansoni cell division control protein 48 aaa family protein 0.0027 0.0105 0.0102
Schistosoma mansoni vam6/vps39 related 0.005 0.0278 0.0275
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0054 0.0126
Echinococcus multilocularis neurogenic locus notch protein 4 0.0025 0.0095 0.0095
Brugia malayi hypothetical protein 0.0024 0.0088 0.021
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Echinococcus multilocularis 0.0122 0.081 0.081
Chlamydia trachomatis pyruvate kinase 0.0032 0.0147 0.5
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0002 0.0004
Schistosoma mansoni neuropeptide receptor 0.0018 0.0043 0.0041
Brugia malayi probable protein kinase 0.0171 0.1182 0.2884
Toxoplasma gondii cell division protein CDC48AP 0.0017 0.0031 0.0076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Entamoeba histolytica hypothetical protein, conserved 0.0304 0.2168 1
Schistosoma mansoni biogenic amine receptor 0.0018 0.0043 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0025 0.0093 0.0455
Schistosoma mansoni hypothetical protein 0.0018 0.0043 0.0041
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0213 0.0515
Trypanosoma brucei unspecified product 0.0037 0.0185 0.0447
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Brugia malayi beta-lactamase family protein 0.0035 0.0166 0.0401
Schistosoma mansoni hypothetical protein 0.0165 0.1131 0.1128
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Echinococcus multilocularis Polycystic kidney disease protein 0.0238 0.1677 0.1677
Onchocerca volvulus 0.0025 0.0095 0.0227
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0048 0.0266 0.0651
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi Serotonin receptor 0.0018 0.0043 0.01
Leishmania major DNA polymerase kappa, putative 0.0037 0.0185 0.0452
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0228 0.16 0.3909
Schistosoma mansoni hypothetical protein 0.0018 0.0043 0.0041
Echinococcus granulosus mitogen activated protein kinase 14 0.0306 0.2181 0.2181
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0018 0.0043 0.01
Brugia malayi vesicle-fusing ATPase 0.0016 0.0029 0.0065
Trichomonas vaginalis endoplasmin, putative 0.0019 0.005 0.0242
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0181 0.1255 0.3067
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0094 0.023
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0025 0.0093 0.0228
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0213 0.0515
Brugia malayi Cadherin domain containing protein 0.0025 0.0095 0.0227
Echinococcus granulosus protein kinase 0.0122 0.081 0.081
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0043 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0088 0.0214
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0025 0.0095 0.0227
Trichomonas vaginalis spermatogenesis associated factor, putative 0.0028 0.0115 0.0566
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0018 0.0043 0.01
Echinococcus multilocularis g-protein coupled receptor 0.0018 0.0043 0.0043
Trypanosoma cruzi heat shock protein 90, putative 0.0032 0.0141 0.0339
Brugia malayi thymidylate synthase 0.0562 0.4092 1
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0095 0.0095
Echinococcus granulosus geminin 0.0165 0.1131 0.113
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0166 0.0332
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0321 0.0712
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0321 0.0318
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Echinococcus granulosus mitogen activated protein kinase 11 0.0306 0.2181 0.2181
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0053 0.0297 0.0297
Onchocerca volvulus 0.0079 0.0491 0.1194
Echinococcus granulosus lamin dm0 0.0026 0.0101 0.0101
Schistosoma mansoni biogenic amine receptor 0.0018 0.0043 0.0041
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Onchocerca volvulus Transitional endoplasmic reticulum ATPase homolog 0.0028 0.0115 0.0276
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Toxoplasma gondii cell division protein CDC48CY 0.0028 0.0115 0.0282
Brugia malayi notch-like transmembrane receptor 0.0025 0.0095 0.0227
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0166 0.0405
Trichomonas vaginalis heat shock protein, putative 0.0019 0.005 0.0242
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0075 0.0464 0.1066
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0095 0.0095
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis protein jagged 2 0.0025 0.0095 0.0095
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0018 0.0043 0.0043
Echinococcus granulosus neuropeptide FF receptor 2 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0215 0.1506 0.368
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0008 0.0006
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0141 0.0339
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0018 0.0043 0.0105
Toxoplasma gondii heat shock protein 75, putative 0.0013 0.0002 0.0006
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0013 0.0002 0.0002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.002 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0213 0.0515
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0185 0.0185
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0043 0.0043
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0095 0.0093
Echinococcus multilocularis heat shock protein 90 0.0032 0.0141 0.0141
Echinococcus multilocularis dna polymerase eta 0.0062 0.0369 0.0369
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0094 0.0225
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.034 0.0338
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0054 0.0054
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0306 0.2181 0.5327
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2088 0.5101
Schistosoma mansoni cpg binding protein 0.006 0.035 0.0348
Brugia malayi Dopamine receptor 0.0018 0.0043 0.01
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0054 0.0126
Brugia malayi Doublecortin family protein 0.0238 0.1677 0.4095
Loa Loa (eye worm) vesicle-fusing ATPase 0.0016 0.0029 0.007
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0042 0.0042
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0054 0.0131
Brugia malayi hypothetical protein 0.0075 0.0464 0.1129
Loa Loa (eye worm) carboxylesterase 0.0075 0.0464 0.1134
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Schistosoma mansoni polycystin 1-related 0.0238 0.1677 0.1675
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0266 0.0646
Mycobacterium ulcerans lipase LipD 0.0035 0.0166 0.0332
Toxoplasma gondii Hsp90 domain-containing protein 0.0013 0.0002 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.0018 0.0043 0.0105
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0043 0.0041
Schistosoma mansoni cell polarity protein 0.0025 0.0095 0.0093
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0939 0.2295
Brugia malayi Pre-SET motif family protein 0.0035 0.0165 0.0398
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.0185 0.0378
Giardia lamblia Pyruvate kinase 0.0032 0.0147 0.059
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0053 0.0297 0.0297
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0152 0.0367
Loa Loa (eye worm) doublecortin family protein 0.0238 0.1677 0.4099
Echinococcus granulosus 7TM GPCR rhodopsin 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0119 0.0791 0.1934
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0074 0.0332
Brugia malayi hypothetical protein 0.0119 0.0791 0.1929
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0018 0.0043 0.01
Leishmania major pyruvate kinase 0.0032 0.0147 0.036
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.002 0.0053 0.0052
Echinococcus granulosus fmrfamide receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0122 0.081 0.198
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.002 0.002
Schistosoma mansoni heat shock protein 0.0032 0.0141 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Schistosoma mansoni lipoxygenase 0.0811 0.5941 0.594
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0054 0.0054
Loa Loa (eye worm) animal heme peroxidase 0.0079 0.0491 0.1199
Echinococcus multilocularis mitogen activated protein kinase 14 0.0306 0.2181 0.2181
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0078 0.0078
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 1
Loa Loa (eye worm) blistered cuticle protein 3 0.0079 0.0491 0.1199
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0293 0.0715
Schistosoma mansoni peroxidasin 0.0079 0.0491 0.0489
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0018 0.0043 0.0043
Echinococcus granulosus hypothetical protein 0.0018 0.0043 0.0043
Brugia malayi hypothetical protein 0.0079 0.0491 0.1194
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Brugia malayi Animal haem peroxidase family protein 0.0079 0.0491 0.1194
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0095 0.0227
Schistosoma mansoni BC026374 protein (S09 family) 0.0075 0.0464 0.0462
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0166 0.0332
Brugia malayi Serotonin receptor 0.0018 0.0043 0.01
Echinococcus multilocularis fat cadherin tumor suppressor 0.0025 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0172 0.1186 0.2898
Echinococcus multilocularis sphingosine kinase 1 0.0304 0.2168 0.2168
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0165 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Echinococcus multilocularis bromodomain containing protein 7 0.0167 0.1148 0.1148
Giardia lamblia Grp94/Hsp90 0.0025 0.0093 0.0318
Echinococcus granulosus peroxidasin 0.0079 0.0491 0.0491
Schistosoma mansoni heat shock protein 0.0032 0.0141 0.0139
Plasmodium vivax pyruvate kinase, putative 0.0032 0.0147 0.0358
Echinococcus multilocularis Bromodomain containing protein 0.0524 0.3805 0.3805
Echinococcus multilocularis serotonin receptor 0.0018 0.0043 0.0043
Onchocerca volvulus 0.0018 0.0043 0.01
Echinococcus granulosus carboxylesterase 5A 0.0444 0.3209 0.3209
Brugia malayi Endoplasmin precursor 0.0032 0.0141 0.0339
Echinococcus multilocularis transitional endoplasmic reticulum atpase 0.0028 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Brugia malayi Protein kinase domain containing protein 0.0161 0.1102 0.2689
Brugia malayi Temporarily assigned gene name protein 59 0.005 0.0278 0.0673
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0088 0.021
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0255 0.0617
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0088 0.021
Onchocerca volvulus 0.0026 0.0101 0.0241
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0213 0.0515
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0018 0.0043 0.0105
Echinococcus granulosus G protein coupled receptor 139 0.0018 0.0043 0.0043
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0054 0.0052
Mycobacterium tuberculosis Carboxylesterase LipT 0.0075 0.0464 0.1066
Plasmodium vivax cell division cycle protein 48 homologue, putative 0.0027 0.0105 0.0254
Echinococcus multilocularis BC026374 protein (S09 family) 0.0075 0.0464 0.0464
Onchocerca volvulus 0.0079 0.0491 0.1194
Schistosoma mansoni microtubule-associated protein tau 0.1356 1 1
Loa Loa (eye worm) beta-lactamase 0.0035 0.0166 0.0406
Schistosoma mansoni rap gtpase-activating protein 0.005 0.0278 0.0275
Echinococcus granulosus flap endonuclease 1 0.0025 0.0094 0.0094
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1453 0.3552
Brugia malayi hypothetical protein 0.023 0.1615 0.3943
Echinococcus granulosus heat shock protein 90 0.0025 0.0093 0.0093
Brugia malayi Dopamine receptor protein 2 0.0018 0.0043 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0018 0.0043 0.0041
Echinococcus multilocularis lamin dm0 0.0026 0.0101 0.0101
Brugia malayi neuropeptide F receptor 0.0018 0.0043 0.01
Onchocerca volvulus 0.0018 0.0043 0.01
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0268 0.1897 0.4634
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0177 0.0426
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0166 0.0332
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0088 0.0214
Plasmodium falciparum phd finger protein, putative 0.0028 0.0117 0.0284
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Echinococcus multilocularis microtubule associated protein 2 0.1356 1 1
Echinococcus multilocularis peroxidasin 0.0079 0.0491 0.0491
Onchocerca volvulus 0.002 0.0054 0.0126
Brugia malayi map kinase activated protein kinase protein 2 0.0181 0.1255 0.3064
Echinococcus multilocularis protein jagged 1 0.0025 0.0095 0.0095
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0147 0.0354
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0166 0.0406
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.005 0.0278 0.0275
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.2018 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0215
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0185 0.0843
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0043 0.0105
Mycobacterium leprae Probable pyruvate kinase PykA 0.0032 0.0147 0.0135
Schistosoma mansoni thyroid hormone receptor 0.002 0.0054 0.0052
Trypanosoma cruzi Valosin-containing protein, putative 0.0027 0.0105 0.025
Onchocerca volvulus 0.005 0.0278 0.0673
Giardia lamblia AAA family ATPase 0.0017 0.0031 0.0008
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0075 0.0464 0.2295
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0166 0.0818
Onchocerca volvulus Chorion peroxidase homolog 0.0079 0.0491 0.1194
Echinococcus granulosus neurogenic locus notch protein 4 0.0025 0.0095 0.0095
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0053 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Onchocerca volvulus 0.0018 0.0043 0.01
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.005 0.0278 0.0673
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Schistosoma mansoni coup transcription factor 0.002 0.0054 0.0052
Trypanosoma brucei unspecified product 0.0026 0.0098 0.0235
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0787 0.5766 0.5766
Plasmodium falciparum cell division cycle protein 48 homologue, putative 0.0027 0.0105 0.0254
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0054 0.0054
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.002 0.002
Schistosoma mansoni bromodomain containing 0.0172 0.1186 0.1184
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0053 0.0297 0.0297
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0147 0.0359
Trypanosoma brucei Heat shock protein 83, putative 0.0032 0.0141 0.0339
Brugia malayi Animal haem peroxidase family protein 0.0079 0.0491 0.1194
Trypanosoma cruzi heat shock protein 85, putative 0.0025 0.0093 0.0222
Echinococcus granulosus neuropeptide s receptor 0.0018 0.0043 0.0043
Schistosoma mansoni gliotactin 0.0075 0.0464 0.0462
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0018 0.0043 0.0041
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Brugia malayi Carboxylesterase family protein 0.0075 0.0464 0.1129
Trypanosoma brucei unspecified product 0.0026 0.0098 0.0235
Echinococcus multilocularis RUN 0.0238 0.1677 0.1677
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0297 0.0295
Onchocerca volvulus 0.0035 0.0166 0.0401
Plasmodium vivax multidomain scavenger receptor, putative 0.0238 0.1677 0.4098
Brugia malayi nuclear receptor NHR-88 0.002 0.0054 0.0126
Schistosoma mansoni neuropeptide receptor 0.0018 0.0043 0.0041
Echinococcus multilocularis cpg binding protein 0.006 0.035 0.035
Brugia malayi intermediate filament protein 0.0026 0.0101 0.0241
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0094 0.0094
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0018 0.0043 0.0043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0042 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Onchocerca volvulus 0.0075 0.0464 0.1129
Echinococcus granulosus protein jagged 2 0.0025 0.0095 0.0095
Trichomonas vaginalis esterase, putative 0.0035 0.0166 0.0818
Echinococcus granulosus slit 2 protein 0.0025 0.0095 0.0095
Brugia malayi Tachykinin-like peptides receptor 99D 0.0018 0.0043 0.01
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0185 0.0185
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.005 0.0278 0.0277
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0054 0.0126
Echinococcus granulosus notch 0.0025 0.0095 0.0095
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0596 0.0596
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0166 0.0818
Echinococcus multilocularis carboxylesterase 5A 0.0444 0.3209 0.3209
Schistosoma mansoni protein kinase 0.0122 0.081 0.0808
Echinococcus multilocularis G-protein coupled receptor, putative 0.0018 0.0043 0.0043
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0141 0.0693
Brugia malayi G-protein coupled receptor 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Onchocerca volvulus 0.0238 0.1677 0.4095
Echinococcus multilocularis serotonin receptor 0.0018 0.0043 0.0043
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0166 0.0332
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Echinococcus multilocularis peregrin 0.0033 0.0154 0.0154
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0562 0.4092 1
Onchocerca volvulus Peroxidasin homolog 0.0079 0.0491 0.1194
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0161 0.1102 0.1102
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus serotonin receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0074 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0054 0.0126
Loa Loa (eye worm) hypothetical protein 0.0026 0.0101 0.0246
Onchocerca volvulus Peroxidasin homolog 0.0079 0.0491 0.1194
Brugia malayi sulfakinin receptor protein 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0117 0.0117
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0043 0.0043
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Echinococcus multilocularis pyruvate kinase 0.0032 0.0147 0.0147
Echinococcus multilocularis neuropeptides capa receptor 0.0018 0.0043 0.0043
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.005 0.0278 0.0275
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus granulosus FTZ F1 alpha 0.002 0.0054 0.0054
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0101 0.0241
Brugia malayi Pre-SET motif family protein 0.0208 0.1453 0.3548
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Echinococcus granulosus heat shock protein 90 0.0032 0.0141 0.0141
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Echinococcus granulosus para nitrobenzyl esterase 0.0075 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0444 0.3209 0.7842
Toxoplasma gondii heat shock protein 90, putative 0.0032 0.0141 0.0344
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0054 0.0131
Onchocerca volvulus 0.0018 0.0043 0.01
Echinococcus multilocularis neuropeptide receptor A26 0.0018 0.0043 0.0043
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Loa Loa (eye worm) animal heme peroxidase 0.0079 0.0491 0.1199
Schistosoma mansoni nuclear hormone receptor 0.002 0.0054 0.0052
Echinococcus multilocularis g protein coupled receptor 0.0018 0.0043 0.0043
Schistosoma mansoni amine GPCR 0.0018 0.0043 0.0041
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Mycobacterium tuberculosis Conserved protein 0.0035 0.0166 0.0332
Echinococcus multilocularis para nitrobenzyl esterase 0.0075 0.0464 0.0464
Echinococcus granulosus transitional endoplasmic reticulum atpase 0.0028 0.0115 0.0115
Leishmania major heat shock protein, putative 0.0013 0.0002 0.0006
Echinococcus granulosus orexin receptor type 2 0.0018 0.0043 0.0043
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0165 0.0163
Schistosoma mansoni histamine h1 receptor 0.0018 0.0043 0.0041
Schistosoma mansoni growth hormone secretagogue receptor 0.0018 0.0043 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Mycobacterium tuberculosis Conserved protein 0.0304 0.2168 0.5263
Schistosoma mansoni lamin 0.0026 0.0101 0.0099
Trypanosoma brucei pyruvate kinase 1, putative 0.0032 0.0147 0.0354
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0166 0.0818
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0095 0.0095
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0018 0.0043 0.0041
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0326 0.0797
Echinococcus granulosus neuropeptide receptor A26 0.0018 0.0043 0.0043
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0032 0.0147 0.0285
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.0782 0.191
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0185 0.0183
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0095 0.0227
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0306 0.2181 0.533
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0054 0.0126
Schistosoma mansoni biogenic amine receptor 0.0018 0.0043 0.0041
Onchocerca volvulus Pyruvate kinase homolog 0.0032 0.0147 0.0354
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0043 0.0043
Echinococcus granulosus arachidonate 5 lipoxygenase 0.1239 0.9129 0.9129
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0117 0.0285
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0166 0.0401
Onchocerca volvulus Slit protein homolog 0.0025 0.0095 0.0227
Brugia malayi Latrophilin receptor protein 2 0.0015 0.002 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.1102 0.11
Echinococcus multilocularis acetylcholinesterase 0.0444 0.3209 0.3209
Onchocerca volvulus 0.0075 0.0464 0.1129
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0161 0.0161
Brugia malayi Dopamine receptor protein 1 0.0018 0.0043 0.01
Plasmodium falciparum heat shock protein 90, putative 0.0013 0.0002 0.0004
Echinococcus granulosus g protein coupled receptor 0.0018 0.0043 0.0043
Mycobacterium ulcerans beta-lactamase 0.0035 0.0166 0.0332
Loa Loa (eye worm) heat shock protein 75 0.0013 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0141 0.064
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0161 0.1102 0.2693
Entamoeba histolytica heat shock protein 90, putative 0.0032 0.0141 0.064
Brugia malayi Animal haem peroxidase family protein 0.0079 0.0491 0.1194
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0094 0.023
Loa Loa (eye worm) Notch2 0.0025 0.0095 0.0232
Brugia malayi beta-lactamase family protein 0.0035 0.0166 0.0401
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0018 0.0043 0.01
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0053 0.0297 0.0297
Schistosoma mansoni hypothetical protein 0.0238 0.1677 0.1675
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1615 0.1615
Schistosoma mansoni thyroid hormone receptor 0.002 0.0054 0.0052
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Schistosoma mansoni adenoreceptor 0.0018 0.0043 0.0041
Schistosoma mansoni opsin-like receptor 0.0018 0.0043 0.0041
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.0938 0.2232
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Brugia malayi follicle stimulating hormone receptor 0.0471 0.3408 0.8327
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.003 0.0072
Echinococcus granulosus sex peptide receptor 0.0018 0.0043 0.0043
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0018 0.0043 0.01
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0161 0.1102 0.2689
Onchocerca volvulus Dual oxidase homolog 0.0079 0.0491 0.1194
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0018 0.0043 0.0041
Toxoplasma gondii hypothetical protein 0.0047 0.0258 0.0631
Onchocerca volvulus Huntingtin homolog 0.0119 0.0791 0.1929
Schistosoma mansoni peroxidasin 0.0079 0.0491 0.0489
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0088 0.0214
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.002 0.002
Onchocerca volvulus 0.0018 0.0043 0.01
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0043 0.0043
Echinococcus multilocularis fibropellin Ia 0.0025 0.0095 0.0095
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0042 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Brugia malayi hypothetical protein 0.0268 0.1897 0.4634
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0185 0.0183
Loa Loa (eye worm) hypothetical protein 0.0444 0.3209 0.7842
Echinococcus granulosus Vam6:Vps39 protein 0.005 0.0278 0.0277
Schistosoma mansoni serine/threonine protein kinase 0.0181 0.1255 0.1253
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0018 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.0018
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.003 0.0073
Brugia malayi Animal haem peroxidase family protein 0.0079 0.0491 0.1194
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0369 0.0897
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi hypothetical protein 0.005 0.0278 0.0673
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0054 0.0052
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0147 0.0723
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0117 0.0114
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0054 0.0052
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Onchocerca volvulus 0.0236 0.1661 0.4056
Schistosoma mansoni hypothetical protein 0.0167 0.1148 0.1146
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus multilocularis notch 0.0025 0.0095 0.0095
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0042 0.0102
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Echinococcus granulosus lamin 0.0026 0.0101 0.0101
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0054 0.0054
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0369 0.0897
Mycobacterium tuberculosis Conserved protein 0.0035 0.0166 0.0332
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Brugia malayi Pyruvate kinase, muscle isozyme 0.0032 0.0147 0.0354
Onchocerca volvulus 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0285
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Loa Loa (eye worm) neuropeptide F receptor 0.0018 0.0043 0.0105
Echinococcus multilocularis sex peptide receptor 0.0018 0.0043 0.0043
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0043 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0054 0.0126
Brugia malayi Carboxylesterase family protein 0.0075 0.0464 0.1129
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Brugia malayi RE15519p 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus pyruvate kinase 0.0017 0.003 0.003
Echinococcus granulosus neuropeptide receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Onchocerca volvulus Peroxidase homolog 0.0079 0.0491 0.1194
Loa Loa (eye worm) hypothetical protein 0.005 0.0278 0.0678
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Toxoplasma gondii exonuclease III APE 0.0018 0.0042 0.0103
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0054 0.0052
Echinococcus granulosus g protein coupled receptor 0.0018 0.0043 0.0043
Brugia malayi hypothetical protein 0.0016 0.0024 0.0052
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0147 0.0354
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0177 0.0432
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0042 0.0097
Echinococcus multilocularis pyruvate kinase 0.0026 0.0096 0.0096
Echinococcus granulosus sphingosine kinase 1 0.0304 0.2168 0.2168
Schistosoma mansoni acetylcholinesterase 0.0075 0.0464 0.0462
Brugia malayi neuropeptide F receptor 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni hypothetical protein 0.0165 0.1131 0.1128
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0165 0.0165
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis neuropeptide receptor 0.0018 0.0043 0.0043
Plasmodium vivax heat shock protein 86, putative 0.0032 0.0141 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0098 0.0235
Brugia malayi Calcium binding EGF domain containing protein 0.0025 0.0095 0.0227
Trichomonas vaginalis set domain proteins, putative 0.0236 0.1661 0.823
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0054 0.0052
Trypanosoma cruzi heat shock protein 90, putative 0.0025 0.0093 0.0222
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.005 0.0278 0.0277
Trypanosoma cruzi pyruvate kinase 2, putative 0.0032 0.0147 0.0354
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0054 0.0054
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Schistosoma mansoni hypothetical protein 0.0047 0.0255 0.0252
Brugia malayi heat shock protein 90 0.0032 0.0141 0.0339
Treponema pallidum heat shock protein 90 0.0025 0.0093 0.0259
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0114 0.0114
Echinococcus granulosus dnaJ subfamily B 0.0804 0.5889 0.5889
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.0938 0.2232
Echinococcus granulosus alpha 1A adrenergic receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) animal heme peroxidase 0.0079 0.0491 0.1199
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0266 0.0646
Onchocerca volvulus 0.0018 0.0043 0.01
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0165 0.0165
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0018 0.0043 0.0041
Schistosoma mansoni myosin xvIII 0.0018 0.0043 0.0041
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0042 0.0097
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0306 0.2181 0.533
Echinococcus granulosus neuroligin 0.0075 0.0464 0.0464
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.2181 0.5327
Brugia malayi larval opioid receptor 0.0018 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi putative neuropeptide receptor NPR1 0.0018 0.0043 0.01
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0321 0.0712
Loa Loa (eye worm) TYRA-2 protein 0.0018 0.0043 0.0105
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0042 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Echinococcus multilocularis fmrfamide receptor 0.0018 0.0043 0.0043
Onchocerca volvulus 0.0018 0.0043 0.01
Loa Loa (eye worm) pyruvate kinase 0.0032 0.0147 0.0359
Echinococcus multilocularis geminin 0.0165 0.1131 0.113
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0043 0.0043
Echinococcus multilocularis lipoxygenase domain containing protein 0.0238 0.1677 0.1677
Echinococcus granulosus biogenic amine 5HT receptor 0.0018 0.0043 0.0043
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0018 0.0043 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Echinococcus multilocularis dro:myosuppressin receptor 0.0018 0.0043 0.0043
Echinococcus granulosus neuropeptide Y receptor 0.0018 0.0043 0.0043
Onchocerca volvulus 0.0035 0.0166 0.0401
Loa Loa (eye worm) G-protein coupled receptor 0.0018 0.0043 0.0105
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0018 0.0043 0.0043
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0185 0.0447
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0042 0.0097
Brugia malayi ORL1-like opioid receptor 0.0018 0.0043 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0054 0.0131
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0185 0.0911
Leishmania major Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog 0.0027 0.0105 0.0255
Schistosoma mansoni ap endonuclease 0.0018 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Onchocerca volvulus 0.0562 0.4092 1
Brugia malayi Bromodomain containing protein 0.0033 0.0154 0.0372
Schistosoma mansoni amine GPCR 0.0018 0.0043 0.0041
Brugia malayi Carboxylesterase family protein 0.0075 0.0464 0.1129
Giardia lamblia PHD finger protein 15 0.0028 0.0117 0.0437
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0939 0.229
Giardia lamblia Heat shock protein HSP 90-alpha 0.0025 0.0093 0.0318
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi Protein kinase domain containing protein 0.0053 0.0297 0.0721
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0025 0.0095 0.0227
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0101 0.0246
Mycobacterium ulcerans heat shock protein 90 0.0025 0.0093 0.0152
Echinococcus granulosus protein jagged 1 0.0025 0.0095 0.0095
Schistosoma mansoni sphingoid long chain base kinase 0.0304 0.2168 0.2167
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0185 0.0378
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.001 0.0025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.005 0.0278 0.0678
Entamoeba histolytica transitional endoplasmic reticulum ATPase, putative 0.0027 0.0105 0.0472
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0165 0.0404
Brugia malayi AKH receptor 0.0018 0.0043 0.01
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0075 0.0464 0.0462
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.1239 0.9129 0.9129
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Echinococcus multilocularis acetylcholinesterase 0.0444 0.3209 0.3209
Brugia malayi Muscle positioning protein 4 0.0025 0.0095 0.0227
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Onchocerca volvulus Neuropeptide F receptor homolog 0.0018 0.0043 0.01
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0054 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0341 0.0833
Onchocerca volvulus Putative cubilin 0.0025 0.0095 0.0227
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus pyruvate kinase 0.0017 0.003 0.003
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0054 0.0131
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0025 0.0093 0.0152
Echinococcus multilocularis neuropeptide Y receptor 0.0018 0.0043 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.001 0.002
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus bromodomain containing protein 7 0.0167 0.1148 0.1148
Plasmodium falciparum heat shock protein 90 0.0032 0.0141 0.0343
Schistosoma mansoni amine GPCR 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.028 0.0679
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0095 0.0095
Schistosoma mansoni neuropeptide receptor 0.0018 0.0043 0.0041
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0166 0.0332
Loa Loa (eye worm) carboxylesterase 0.0075 0.0464 0.1134
Brugia malayi Flap endonuclease-1 0.0025 0.0094 0.0225
Loa Loa (eye worm) hypothetical protein 0.0075 0.0464 0.1134
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0054 0.0054
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0054 0.0054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0054 0.0126
Echinococcus multilocularis G protein coupled receptor 139 0.0018 0.0043 0.0043
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0321 0.0778
Loa Loa (eye worm) hypothetical protein 0.0238 0.1677 0.4099
Schistosoma mansoni endoplasmin 0.0032 0.0141 0.0139
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Schistosoma mansoni rab6-interacting 0.0238 0.1677 0.1675
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0075 0.0464 0.1066
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0013 0.0002 0.0002
Echinococcus granulosus peregrin 0.0033 0.0154 0.0154
Schistosoma mansoni hypothetical protein 0.0804 0.5889 0.5888
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0042 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Mycobacterium ulcerans hypothetical protein 0.0154 0.1056 0.2523
Loa Loa (eye worm) hypothetical protein 0.0119 0.0791 0.1934
Echinococcus granulosus fibropellin Ia 0.0025 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.0839 0.0837
Plasmodium falciparum LCCL domain-containing protein 0.0238 0.1677 0.4098
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.0185 0.0452
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.2018 1
Echinococcus granulosus Bromodomain containing protein 0.0524 0.3805 0.3805
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0054 0.0126
Echinococcus multilocularis neuropeptide FF receptor 2 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0043 0.0041
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0042 0.0202
Schistosoma mansoni cpg binding protein 0.006 0.035 0.0348
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0306 0.2181 0.5327
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0054 0.0054
Onchocerca volvulus Peroxidase homolog 0.0079 0.0491 0.1194
Echinococcus granulosus tm gpcr rhodopsin 0.0018 0.0043 0.0043
Echinococcus multilocularis musashi 0.0026 0.0101 0.0101
Schistosoma mansoni neuroligin 3 (S09 family) 0.0075 0.0464 0.0462
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Toxoplasma gondii EGF family domain-containing protein 0.0025 0.0095 0.0232
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0181 0.1255 0.1255
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0054 0.0054
Trypanosoma brucei heat shock protein 90, putative 0.0032 0.0141 0.0339
Onchocerca volvulus 0.0018 0.0043 0.01
Schistosoma mansoni neuropeptide f receptor 76f 0.0018 0.0043 0.0041
Echinococcus granulosus lipoxygenase domain containing protein 0.0238 0.1677 0.1677
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0166 0.0401
Trichomonas vaginalis heat shock protein, putative 0.0013 0.0002 0.0005
Echinococcus multilocularis slit 2 protein 0.0025 0.0095 0.0095
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0166 0.0166
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.005 0.0278 0.0275
Echinococcus granulosus RUN 0.0238 0.1677 0.1677
Echinococcus granulosus pyruvate kinase 0.0032 0.0147 0.0147
Trichomonas vaginalis pyruvate kinase, putative 0.0032 0.0147 0.0723
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0054 0.0126
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0075 0.0464 0.0462
Loa Loa (eye worm) hypothetical protein 0.0035 0.0165 0.0403
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Brugia malayi hypothetical protein 0.0238 0.1677 0.4095
Onchocerca volvulus Alhambra homolog 0.0028 0.0117 0.028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni biogenic amine (5HT) receptor 0.0018 0.0043 0.0041
Onchocerca volvulus 0.0018 0.0043 0.01
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0293 0.2088 0.5101
Schistosoma mansoni neuropeptide receptor 0.0018 0.0043 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Echinococcus granulosus somatostatin receptor 0.0018 0.0043 0.0043
Onchocerca volvulus 0.0025 0.0095 0.0227
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0053 0.0052
Echinococcus granulosus endoplasmin 0.0025 0.0093 0.0093
Echinococcus granulosus mixed lineage leukemia protein mll 0.002 0.0053 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0054 0.0126
Echinococcus multilocularis neuropeptide s receptor 0.0018 0.0043 0.0043
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus granulosus neurogenic locus protein delta 0.0025 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Trypanosoma brucei heat shock protein, putative 0.0032 0.0141 0.0339
Echinococcus multilocularis thymidylate synthase 0.0562 0.4092 0.4092
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0117 0.0285
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0166 0.0166
Echinococcus multilocularis somatostatin receptor 0.0018 0.0043 0.0043
Schistosoma mansoni endoplasmin 0.0032 0.0141 0.0139
Loa Loa (eye worm) hypothetical protein 0.002 0.0054 0.0131
Echinococcus granulosus rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Schistosoma mansoni lipoxygenase 0.1239 0.9129 0.9129
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0094 0.0229
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0166 0.0818
Echinococcus granulosus lipoxygenase domain containing protein 0.0238 0.1677 0.1677
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0018 0.0043 0.0041
Trypanosoma brucei Valosin-containing protein 0.0027 0.0105 0.025
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0018 0.0043 0.01
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0042 0.0097
Echinococcus granulosus dro:myosuppressin receptor 0.0018 0.0043 0.0043
Schistosoma mansoni cpg binding protein 0.0056 0.0326 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0268 0.1897 0.9402
Mycobacterium tuberculosis Hypothetical protein 0.0268 0.1897 0.4596
Echinococcus granulosus tachykinin peptides receptor 99D 0.0018 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.023 0.1615 0.3946
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0025 0.0093 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0166 0.0332
Loa Loa (eye worm) hypothetical protein 0.0062 0.0369 0.0902
Toxoplasma gondii ABC1 family protein 0.0035 0.0166 0.0406
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0075 0.0464 0.0462
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0018 0.0043 0.0041
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0321 0.0712
Brugia malayi Animal haem peroxidase family protein 0.0079 0.0491 0.1194
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1568 0.3785
Brugia malayi steroid hormone receptor 0.002 0.0054 0.0126
Onchocerca volvulus 0.0075 0.0464 0.1129
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0054 0.0126
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.005 0.0278 0.0673
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0185 0.0447
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0221 0.1548 0.1548
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0054 0.0054
Brugia malayi Carboxylesterase family protein 0.0444 0.3209 0.7841
Brugia malayi Pyruvate kinase, M2 isozyme 0.0032 0.0147 0.0354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0152 0.0372
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0054 0.0126
Plasmodium falciparum endoplasmin, putative 0.0019 0.005 0.0121
Echinococcus granulosus protein jagged 2 0.0025 0.0095 0.0095
Mycobacterium ulcerans carboxylesterase, LipT 0.0075 0.0464 0.1066
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0094 0.0324
Brugia malayi P38 map kinase family protein 2 0.0306 0.2181 0.5327
Leishmania major hypothetical protein, conserved 0.0035 0.0166 0.0406
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0293 0.2088 0.5101
Brugia malayi G-protein coupled receptor 0.0018 0.0043 0.01
Giardia lamblia High cysteine protein 0.0025 0.0095 0.0328
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0185 0.0185
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 1
Echinococcus multilocularis orexin receptor type 2 0.0018 0.0043 0.0043
Onchocerca volvulus 0.0035 0.0166 0.0401
Leishmania major DNA polymerase eta, putative 0.0036 0.0177 0.0432
Plasmodium vivax heat shock protein 90, putative 0.0013 0.0002 0.0004
Leishmania major pyruvate kinase 0.0032 0.0147 0.036
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0117 0.0284
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0166 0.0818
Schistosoma mansoni loxhd1 0.0238 0.1677 0.1675
Onchocerca volvulus 0.0079 0.0491 0.1194
Schistosoma mansoni pyruvate kinase 0.0032 0.0147 0.0145
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0043 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0018 0.0043 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Mycobacterium ulcerans thymidylate synthase 0.0562 0.4092 1
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.0018
Plasmodium falciparum pyruvate kinase 2 0.0017 0.003 0.0072
Brugia malayi G protein-coupled receptor 0.0018 0.0043 0.01
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0165 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0054 0.0126
Echinococcus granulosus intermediate filament protein 0.0026 0.0101 0.0101
Schistosoma mansoni neuropeptide F-like receptor 0.0018 0.0043 0.0041
Brugia malayi GCC2 and GCC3 family protein 0.0025 0.0095 0.0227
Brugia malayi hypothetical protein 0.0018 0.0043 0.01
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0045 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0166 0.0406
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0054 0.0054
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0042 0.0026
Onchocerca volvulus 0.0025 0.0095 0.0227
Brugia malayi PHD-finger family protein 0.0028 0.0117 0.028
Loa Loa (eye worm) notch protein 0.0025 0.0095 0.0232
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Brugia malayi Melatonin receptor type 1A 0.0018 0.0043 0.01
Loa Loa (eye worm) histone methyltransferase 0.0023 0.0078 0.0191
Plasmodium vivax heat shock protein, putative 0.0013 0.0002 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0088 0.021
Plasmodium falciparum pyruvate kinase 0.0032 0.0147 0.0358
Schistosoma mansoni opsin-like receptor 0.0018 0.0043 0.0041
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0166 0.0183
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0018 0.0043 0.0105
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.2018 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0185 0.0378
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Onchocerca volvulus 0.0018 0.0043 0.01
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0054 0.0131
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis pyruvate kinase 0.0032 0.0147 0.0147
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0094 0.0424
Echinococcus multilocularis mitogen activated protein kinase 11 0.0306 0.2181 0.2181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0018 0.0043 0.0043
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0018 0.0043 0.0043
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0181 0.1255 0.1255
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0228 0.16 0.3909
Echinococcus multilocularis heat shock protein 90 0.0025 0.0093 0.0093
Echinococcus granulosus 7tm_1 domain containing protein 0.0018 0.0043 0.0043
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0369 0.0897
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0098 0.0235
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0185 0.0447
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0121 0.0119
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0185 0.0447
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0232
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Brugia malayi hypothetical protein 0.0238 0.1677 0.4095
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0018 0.0043 0.0043
Echinococcus multilocularis neural cadherin 0.0025 0.0095 0.0095
Brugia malayi nuclear hormone receptor 0.002 0.0054 0.0126
Echinococcus granulosus allatostatin A receptor 0.0018 0.0043 0.0043
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0562 0.4092 1
Schistosoma mansoni amine GPCR 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0238
Schistosoma mansoni ap endonuclease 0.0018 0.0042 0.004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0018 0.0043 0.0043
Echinococcus multilocularis neuroligin 0.0075 0.0464 0.0464
Schistosoma mansoni notch 0.0025 0.0095 0.0093
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.2018 0.9306
Schistosoma mansoni hypothetical protein 0.0015 0.002 0.0018
Brugia malayi EGF-like domain containing protein 0.0025 0.0095 0.0227
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0185 0.0183
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0117 0.0285
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0562 0.4092 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus granulosus delta-like protein 1 0.0025 0.0095 0.0095
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Echinococcus granulosus SET and MYND domain containing protein 3 0.0221 0.1548 0.1548
Loa Loa (eye worm) hypothetical protein 0.0015 0.002 0.0049
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1056 0.2523
Mycobacterium ulcerans pyruvate kinase 0.0032 0.0147 0.0285
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Mycobacterium ulcerans hypothetical protein 0.0304 0.2168 0.5263
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0166 0.0401
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0075 0.0464 0.0464
Leishmania major heat shock protein 83-1 0.0032 0.0141 0.0344
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0054 0.0054
Loa Loa (eye worm) heat shock protein 90 0.0032 0.0141 0.0344
Schistosoma mansoni rab6-interacting 0.0238 0.1677 0.1675
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Loa Loa (eye worm) hypothetical protein 0.0018 0.0043 0.0105
Echinococcus multilocularis neurogenic locus protein delta 0.0025 0.0095 0.0095
Trypanosoma cruzi heat shock protein 85, putative 0.0032 0.0141 0.0339
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0185 0.0911
Mycobacterium leprae Probable lipase LipE 0.0035 0.0166 0.0183
Onchocerca volvulus 0.0025 0.0095 0.0227
Echinococcus granulosus dna polymerase kappa 0.0037 0.0185 0.0185
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0185 0.0378
Loa Loa (eye worm) carboxylesterase 0.0444 0.3209 0.7842
Loa Loa (eye worm) hypothetical protein 0.0049 0.0267 0.0653
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0018 0.0043 0.0041
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0094 0.0225
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0018 0.0043 0.0041
Loa Loa (eye worm) hypothetical protein 0.0079 0.0491 0.1199
Echinococcus granulosus pyruvate kinase 0.0032 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0025 0.0095 0.0093
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0054 0.0131
Onchocerca volvulus 0.0047 0.0255 0.0617
Toxoplasma gondii transitional endoplasmic reticulum ATPase, putative 0.0017 0.0031 0.0076

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8.6 nM Inhibition of human p38alpha expressed in Escherichia coli using MBP as substrate preincubated for 10 mins prior to substrate addition measured after 45 mins by microbeta scintillation counting analysis ChEMBL. 23746475
IC50 (binding) = 1514 nM Inhibition of human p38beta expressed in Escherichia coli using MBP as substrate preincubated for 10 mins prior to substrate addition measured after 45 mins by microbeta scintillation counting analysis ChEMBL. 23746475

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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