Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.3256 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0022 | 0.3256 | 0.3256 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.3256 | 0.3256 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.3256 | 0.3256 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.3256 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 0.3256 | 0.3256 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.3256 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 0.3256 | 0.3256 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 0.3256 | 0.3256 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0022 | 0.3256 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0.3256 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.3256 | 0.5 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | unspecified product | 0.0022 | 0.3256 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.3256 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0022 | 0.3256 | 0.5 |
Echinococcus granulosus | dna polymerase eta | 0.0022 | 0.3256 | 0.3256 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0022 | 0.3256 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0.3256 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.3256 | 0.3256 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.3256 | 0.3256 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 0.3256 | 0.3256 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.3256 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 0.3256 | 0.3256 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0022 | 0.3256 | 0.5 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0022 | 0.3256 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0022 | 0.3256 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0022 | 0.3256 | 0.3256 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.001 | 0 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0022 | 0.3256 | 0.5 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Leishmania major | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 0.5 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.001 | 0 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.3256 | 0.3256 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0022 | 0.3256 | 1 |
Onchocerca volvulus | 0.001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.