Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.1088 | 0.4882 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.1088 | 0.4882 | 0.4882 |
Schistosoma mansoni | acetylcholinesterase | 0.0345 | 0.0885 | 0.0885 |
Brugia malayi | Carboxylesterase family protein | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0556 | 0.2022 | 0.2022 |
Echinococcus multilocularis | acetylcholinesterase | 0.2039 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.2039 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0345 | 0.0885 | 0.0885 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.1035 | 0.4596 | 0.4596 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0345 | 0.0885 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0345 | 0.0885 | 0.0885 |
Echinococcus multilocularis | acetylcholinesterase | 0.2039 | 1 | 1 |
Onchocerca volvulus | 0.0345 | 0.0885 | 1 | |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.1035 | 0.4596 | 0.4596 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | carboxylesterase | 0.0345 | 0.0885 | 0.0885 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0345 | 0.0885 | 0.5 |
Onchocerca volvulus | 0.0345 | 0.0885 | 1 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2039 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0345 | 0.0885 | 0.0885 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.2039 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.1035 | 0.4596 | 0.4596 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Brugia malayi | Carboxylesterase family protein | 0.0345 | 0.0885 | 0.0885 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.018 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0345 | 0.0885 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0345 | 0.0885 | 0.0885 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0345 | 0.0885 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.1088 | 0.4882 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.2039 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0345 | 0.0885 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0345 | 0.0885 | 0.0885 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.1088 | 0.4882 | 0.4882 |
Loa Loa (eye worm) | carboxylesterase | 0.2039 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Schistosoma mansoni | gliotactin | 0.0345 | 0.0885 | 0.0885 |
Onchocerca volvulus | 0.0345 | 0.0885 | 1 | |
Echinococcus granulosus | carboxylesterase 5A | 0.2039 | 1 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0723 | 0.2921 | 0.2921 |
Loa Loa (eye worm) | carboxylesterase | 0.0345 | 0.0885 | 0.0885 |
Onchocerca volvulus | 0.0345 | 0.0885 | 1 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Onchocerca volvulus | 0.0345 | 0.0885 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.0885 | 0.0885 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0345 | 0.0885 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.2039 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0345 | 0.0885 | 0.0885 |
Echinococcus granulosus | acetylcholinesterase | 0.2039 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2039 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0345 | 0.0885 | 0.0885 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2039 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0345 | 0.0885 | 0.0885 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.1088 | 0.4882 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.