Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.0926 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0156 | 0.1279 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0156 | 0.1279 | 0.0101 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0156 | 0.1279 | 0.0331 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0156 | 0.1279 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0156 | 0.1279 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0926 | 1 | 1 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0156 | 0.1279 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0174 | 0.1474 | 0.1474 |
Echinococcus multilocularis | acetylcholinesterase | 0.0926 | 1 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0136 | 0.1051 | 0.0079 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0156 | 0.1279 | 0.1279 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0136 | 0.1051 | 0.1051 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0156 | 0.1279 | 0.1279 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0174 | 0.1474 | 0.0548 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0926 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0156 | 0.1279 | 0.0331 |
Echinococcus granulosus | neuroligin | 0.0156 | 0.1279 | 0.0331 |
Brugia malayi | Carboxylesterase family protein | 0.0926 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.013 | 0.098 | 0.098 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0156 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | carboxylesterase | 0.0926 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0156 | 0.1279 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0926 | 1 | 1 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0926 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0926 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0156 | 0.1279 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0926 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0926 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0156 | 0.1279 | 0.0331 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0926 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0156 | 0.1279 | 0.1279 |
Schistosoma mansoni | acetylcholinesterase | 0.0156 | 0.1279 | 0.0101 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.