Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0136 | 0.1051 | 0.1051 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0926 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0156 | 0.1279 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0926 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0156 | 0.1279 | 0.0331 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0156 | 0.1279 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0156 | 0.1279 | 0.5 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0156 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0926 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0156 | 0.1279 | 0.0331 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0156 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | carboxylesterase | 0.0926 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0926 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0156 | 0.1279 | 0.0331 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0156 | 0.1279 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0156 | 0.1279 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0136 | 0.1051 | 0.0079 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0174 | 0.1474 | 0.0548 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0156 | 0.1279 | 0.0331 |
Echinococcus multilocularis | acetylcholinesterase | 0.0926 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0174 | 0.1474 | 0.1474 |
Echinococcus granulosus | carboxylesterase 5A | 0.0926 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0926 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0926 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | neuroligin | 0.0156 | 0.1279 | 0.1279 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0926 | 1 | 1 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0156 | 0.1279 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0926 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.013 | 0.098 | 0.098 |
Onchocerca volvulus | 0.0156 | 0.1279 | 0.5 | |
Schistosoma mansoni | acetylcholinesterase | 0.0156 | 0.1279 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0926 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0156 | 0.1279 | 0.0101 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0156 | 0.1279 | 0.1279 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.