Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | protein kinase C, delta | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Onchocerca volvulus | Get druggable targets OG5_132502 | All targets in OG5_132502 | |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Loa Loa (eye worm) | hypothetical protein | Get druggable targets OG5_132502 | All targets in OG5_132502 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.0023 | 0.003 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Onchocerca volvulus | 0.0167 | 0.861 | 0.5 | |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0162 | 0.8358 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0023 | 0.003 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.861 | 0.8606 |
Schistosoma mansoni | atypical protein kinase C | 0.004 | 0.1012 | 0.118 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.8358 | 0.8353 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0162 | 0.8358 | 1 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0162 | 0.8358 | 1 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0023 | 0.003 | 0.5 |
Echinococcus multilocularis | protein kinase c iota type | 0.004 | 0.1012 | 0.118 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0089 | 0.3952 | 0.4709 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.861 | 0.8606 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0041 | 0.1103 | 0.1289 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0023 | 0.003 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0023 | 0.003 | 0.5 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0162 | 0.8358 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.861 | 0.8606 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0048 | 0.1489 | 0.1752 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0162 | 0.8358 | 0.8353 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0162 | 0.8358 | 1 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.005 | 0.161 | 0.1584 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0162 | 0.8358 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0041 | 0.1103 | 0.1289 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.8358 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.004 | 0.1012 | 0.118 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1489 | 0.1463 |
Toxoplasma gondii | AGC kinase | 0.0023 | 0.003 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.3952 | 0.4709 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.9593 | 0.9592 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.8358 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0162 | 0.8358 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.2471 | 0.2449 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0072 | 0.2969 | 0.3529 |
Brugia malayi | protein kinase C II. | 0.0041 | 0.1103 | 0.1289 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.3952 | 0.4709 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0089 | 0.3952 | 0.4709 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0048 | 0.1489 | 0.1752 |
Echinococcus granulosus | protein kinase C gamma type | 0.0072 | 0.2969 | 0.3529 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Brugia malayi | Protein kinase c protein 2 | 0.0066 | 0.2592 | 0.3076 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0041 | 0.1103 | 0.1076 |
Schistosoma mansoni | apoptosis regulator bax | 0.0162 | 0.8358 | 1 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0048 | 0.1489 | 0.1752 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0041 | 0.1103 | 0.1289 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0023 | 0.003 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.