Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | atypical protein kinase C | 0.0072 | 0.1861 | 0.2372 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0122 | 0.5 | 0.6371 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.4943 | 0.4943 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0091 | 0.3082 | 0.3927 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0081 | 0.2424 | 1 |
Brugia malayi | Protein kinase c protein 2 | 0.0126 | 0.5273 | 0.7391 |
Echinococcus granulosus | protein kinase C gamma type | 0.0137 | 0.5987 | 0.7628 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.9229 | 0.9229 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.3082 | 0.3082 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Echinococcus multilocularis | protein kinase c iota type | 0.0072 | 0.1861 | 0.2372 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Toxoplasma gondii | AGC kinase | 0.0042 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0042 | 0 | 0.5 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0091 | 0.3082 | 0.3927 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0156 | 0.7134 | 0.909 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0091 | 0.3082 | 0.3927 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0167 | 0.7849 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0096 | 0.3411 | 0.3411 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0167 | 0.7849 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.7367 | 0.7367 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.7367 | 0.7367 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.7367 | 0.7367 |
Onchocerca volvulus | 0.0159 | 0.7367 | 0.5 | |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0167 | 0.7849 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0137 | 0.5987 | 0.7628 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0156 | 0.7134 | 0.909 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0156 | 0.7134 | 0.909 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0081 | 0.2424 | 0.3089 |
Brugia malayi | protein kinase C II. | 0.0156 | 0.7134 | 1 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0167 | 0.7849 | 1 |
Echinococcus granulosus | protein kinase c iota type | 0.0072 | 0.1861 | 0.2372 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0156 | 0.7134 | 0.7134 |
Trichomonas vaginalis | AGC family protein kinase | 0.0042 | 0 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 11312916 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.