Detailed information for compound 1789218

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 266.298 | Formula: C15H14N4O
  • H donors: 3 H acceptors: 1 LogP: 1.93 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)Nc1ccc(c2c1c(=O)[nH]cn2)N
  • InChi: 1S/C15H14N4O/c1-9-3-2-4-10(7-9)19-12-6-5-11(16)14-13(12)15(20)18-8-17-14/h2-8,19H,16H2,1H3,(H,17,18,20)
  • InChiKey: YIYUIMZGHISONO-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi cytokine inducible SH2-containing protein 5 0.0029 0.0054 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0056 0.0153 0.0151
Echinococcus granulosus survival motor neuron protein 1 0.0214 0.0725 0.0723
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.017 0.0566 0.0566
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0075
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.0167 0.1339
Loa Loa (eye worm) protein tyrosine phosphatase 0.0049 0.0129 0.0129
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0076 0.0074
Brugia malayi calpain 5 0.0019 0.0019 0.0048
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0009 0.0006
Onchocerca volvulus 0.0037 0.0084 0.0935
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0365
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Echinococcus granulosus G protein coupled receptor kinase 1 0.2412 0.8705 0.8705
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0278
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Onchocerca volvulus 0.0049 0.0129 0.1442
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Mycobacterium leprae Probable lipase LipE 0.0037 0.0084 1
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0111 0.0109
Onchocerca volvulus 0.0032 0.0067 0.0745
Brugia malayi Protein-tyrosine phosphatase 0.0049 0.0129 0.0336
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0068 0.0198 0.2088
Mycobacterium ulcerans lipase LipD 0.0037 0.0084 0.1524
Trypanosoma cruzi NIMA-related kinase, putative 0.0068 0.0198 0.2088
Echinococcus granulosus tyrosine protein kinase Src42A 0.0032 0.0067 0.0065
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0049 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trypanosoma brucei antigen, putative 0.0019 0.0019 0.0195
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0039 0.0091 0.0958
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Brugia malayi hypothetical protein 0.0049 0.0129 0.0336
Mycobacterium ulcerans beta-lactamase 0.0037 0.0084 0.1524
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Onchocerca volvulus 0.0049 0.0129 0.1442
Trypanosoma cruzi kinesin, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.0082
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0082 0.008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0301 0.03
Loa Loa (eye worm) hypothetical protein 0.0063 0.0179 0.0179
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0032 0.0067 0.0065
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Echinococcus multilocularis N chimaerin 0.0029 0.0054 0.0052
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.006 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0029 0.0054 0.0052
Brugia malayi PXA domain containing protein 0.0357 0.1246 0.3238
Onchocerca volvulus 0.0029 0.0054 0.0605
Schistosoma mansoni hypothetical protein 0.0044 0.0109 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Schistosoma mansoni signal transduction protein lnk-related 0.0029 0.0054 0.0053
Loa Loa (eye worm) SRC-1 0.0032 0.0067 0.0067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0806 0.2876 0.7475
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.013 0.0423 0.4458
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0082 0.0081
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Trichomonas vaginalis kinesin light chain, putative 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Echinococcus granulosus microtubule associated protein 2 0.0697 0.2481 0.2479
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0049 0.0129 0.0129
Onchocerca volvulus 0.006 0.0167 0.1859
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0668
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.009
Onchocerca volvulus Huntingtin homolog 0.0111 0.0352 0.3925
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0083 0.0081
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0084 0.0949
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0039 0.0091 0.0958
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0049 0.0129 0.0128
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0207
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0084 0.4118
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0082 0.0869
Loa Loa (eye worm) hypothetical protein 0.0049 0.0128 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus granulosus SHC transforming protein 3 0.0029 0.0054 0.0052
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0075
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0207
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0289 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.0076
Schistosoma mansoni rho gtpase activating protein 0.006 0.0167 0.0166
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0076 0.0074
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.0207
Onchocerca volvulus 0.0049 0.0129 0.1442
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0049 0.0129 0.0128
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Echinococcus granulosus cytohesin 1 0.006 0.0167 0.0164
Toxoplasma gondii hypothetical protein 0.006 0.0167 0.2844
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.006 0.0167 0.0164
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0035 0.0459
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0668
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0024 0.0189
Onchocerca volvulus outspread protein homolog 0.006 0.0167 0.1859
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0029 0.0054 0.0052
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.004 0.0422
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0084 0.0673
Brugia malayi hypothetical protein 0.0049 0.0129 0.0336
Schistosoma mansoni hypothetical protein 0.0028 0.0054 0.0053
Loa Loa (eye worm) rho-GTPase-activating 0.006 0.0167 0.0167
Echinococcus multilocularis SH2 motif 0.0029 0.0054 0.0052
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0039 0.0039
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0009 0.009
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0164 0.0164
Echinococcus multilocularis GRB2 associated binding protein 3 0.006 0.0167 0.0164
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0084 0.0949
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0084 0.0673
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.006 0.0167 0.0167
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.013 0.0423 0.4458
Brugia malayi STAT protein, DNA binding domain containing protein 0.0029 0.0054 0.0141
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0032 0.0067 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.009
Schistosoma mansoni myotubularin-related protein 0.006 0.0167 0.0166
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.004 0.1856
Echinococcus multilocularis dna polymerase kappa 0.0019 0.002 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0006
Trichomonas vaginalis esterase, putative 0.0037 0.0084 0.0673
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus tyrosine protein kinase Src64B 0.0032 0.0067 0.0065
Onchocerca volvulus 0.0089 0.0273 0.3039
Onchocerca volvulus 0.0049 0.0129 0.1442
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Schistosoma mansoni serine/threonine-protein kinase 0.0068 0.0198 0.0197
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.0207
Brugia malayi Regulator of G protein signaling domain containing protein 0.0357 0.1246 0.3238
Echinococcus multilocularis c src tyrosine kinase 0.0032 0.0067 0.0065
Schistosoma mansoni pcd6 interacting protein-related 0.0049 0.0129 0.0128
Trypanosoma brucei rac serine-threonine kinase, putative 0.0068 0.0198 0.2088
Schistosoma mansoni hypothetical protein 0.006 0.0167 0.0166
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0185 0.0482
Echinococcus multilocularis pleckstrin y domain containing family A 0.006 0.0167 0.0164
Toxoplasma gondii protein kinase domain-containing protein 0.0068 0.0198 0.3404
Schistosoma mansoni calpain (C02 family) 0.0019 0.0019 0.0017
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0049 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0056 0.0153 0.0151
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0079 0.0637
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus granulosus Regulator of G protein signaling 20 0.0357 0.1246 0.1244
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0301 0.0298
Loa Loa (eye worm) MH2 domain-containing protein 0.0103 0.0325 0.0325
Echinococcus granulosus N chimaerin 0.0029 0.0054 0.0052
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Loa Loa (eye worm) fli-1 protein 0.0215 0.0729 0.0729
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus granulosus Oxysterol binding protein 11 0.006 0.0167 0.0164
Onchocerca volvulus 0.0049 0.0129 0.1442
Echinococcus granulosus calpain A 0.0019 0.0019 0.0016
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.0337 0.0336
Onchocerca volvulus 0.0029 0.0054 0.0605
Echinococcus multilocularis dna polymerase eta 0.0019 0.002 0.0017
Brugia malayi A-kinase anchor protein 10, precursor 0.0357 0.1246 0.3238
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0613 0.2176 0.2176
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0053
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0009 0.0235
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0548 0.0546
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0068 0.0198 0.2088
Entamoeba histolytica hypothetical protein 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0067
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.0167 0.1339
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0068 0.0198 0.2088
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Schistosoma mansoni tensin-related 0.0029 0.0054 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0084 0.0083
Entamoeba histolytica hypothetical protein 0.0357 0.1246 1
Onchocerca volvulus 0.006 0.0167 0.1859
Schistosoma mansoni alpha-glucosidase 0.0142 0.0465 0.0464
Brugia malayi Syntrophin-1 0.006 0.0167 0.0433
Echinococcus multilocularis Rho GTPase activating protein 24 0.006 0.0167 0.0164
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.006 0.0167 0.1859
Brugia malayi Protein kinase domain containing protein 0.0068 0.0198 0.0514
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0082 0.008
Onchocerca volvulus 0.0049 0.0129 0.1442
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0035 0.0079 0.1428
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.006 0.0167 0.8394
Onchocerca volvulus 0.006 0.0167 0.1859
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0077 0.0229 0.0226
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.0337 0.0335
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.019 0.0188
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus multilocularis microtubule associated protein 2 0.0697 0.2481 0.2479
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.006 0.0167 0.0164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0301 0.03
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0077 0.0229 0.0226
Schistosoma mansoni regulator of G protein signaling 0.0357 0.1246 0.1245
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Echinococcus granulosus hypothetical protein 0.0029 0.0054 0.0052
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0035 0.0459
Onchocerca volvulus 0.0029 0.0054 0.0605
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.002 0.0017
Echinococcus granulosus GRB2 associated binding protein 3 0.006 0.0167 0.0164
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0035 0.0079 0.0838
Brugia malayi jmjC domain containing protein 0.0039 0.0094 0.0244
Brugia malayi hypothetical protein 0.0049 0.0129 0.0336
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0035 0.0033
Trichomonas vaginalis centaurin/arf, putative 0.006 0.0167 0.1339
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0357 0.1246 0.1245
Schistosoma mansoni goodpasture antigen-binding protein 0.006 0.0167 0.0166
Brugia malayi Protein-tyrosine phosphatase 0.0049 0.0129 0.0336
Schistosoma mansoni syntrophin 0.006 0.0167 0.0166
Echinococcus multilocularis tyrosine protein kinase Blk 0.0032 0.0067 0.0065
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0035 0.0328
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0717 0.2552 0.6633
Schistosoma mansoni tensin 0.0029 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Trichomonas vaginalis centaurin/arf, putative 0.006 0.0167 0.1339
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0301 0.0298
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0019 0.0195
Toxoplasma gondii hypothetical protein 0.0044 0.0111 0.185
Onchocerca volvulus 0.006 0.0167 0.1859
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0032 0.0067 0.0065
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0049 0.0129 0.0127
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0173 0.0578 0.0578
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Schistosoma mansoni SH2A 0.0029 0.0054 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trichomonas vaginalis pten, drome, putative 0.0049 0.0129 0.1038
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0613 0.2176 0.2174
Brugia malayi hypothetical protein 0.0032 0.0067 0.0174
Brugia malayi Pre-SET motif family protein 0.0035 0.0076 0.0198
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0032 0.0067 0.0065
Echinococcus granulosus protein tyrosine phosphatase n9 0.0049 0.0129 0.0127
Echinococcus multilocularis musashi 0.0024 0.0039 0.0037
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.006 0.0167 0.0164
Trypanosoma brucei unspecified product 0.0019 0.002 0.0207
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.006 0.0167 0.0164
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Echinococcus multilocularis cytohesin 1 0.006 0.0167 0.0164
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Brugia malayi Tensin 0.0029 0.0054 0.0141
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Onchocerca volvulus 0.006 0.0167 0.1859
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Onchocerca volvulus 0.0049 0.0129 0.1442
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0049 0.0129 0.0128
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0613 0.2176 0.5655
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.006 0.0167 0.0164
Echinococcus multilocularis hypothetical protein 0.0019 0.0019 0.0016
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0082 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Entamoeba histolytica hypothetical protein 0.0068 0.0198 0.1589
Echinococcus granulosus SH2 domain containing adapter protein F 0.0029 0.0054 0.0052
Onchocerca volvulus 0.0049 0.0129 0.1442
Schistosoma mansoni adapter molecule crk 0.0029 0.0054 0.0053
Onchocerca volvulus 0.0032 0.0067 0.0745
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0357 0.1246 1
Echinococcus granulosus cpg binding protein 0.0094 0.0291 0.0289
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus tyrosine protein kinase Src42A 0.0029 0.0054 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0088 0.027 0.027
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0082 0.0661
Entamoeba histolytica hypothetical protein 0.0106 0.0337 0.2705
Onchocerca volvulus 0.0261 0.0897 1
Schistosoma mansoni regulator of G protein signaling 0.0357 0.1246 0.1245
Brugia malayi Cadps2 protein 0.006 0.0167 0.0433
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0068 0.0198 0.2088
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0275 0.0948 1
Brugia malayi calpain family protein 1 0.0063 0.0179 0.0465
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0189 0.0638 0.0637
Echinococcus granulosus regulator of G protein signaling 7 0.0357 0.1246 0.1244
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0068 0.0198 0.3404
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0049 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0032 0.0067 0.0065
Schistosoma mansoni hypothetical protein 0.006 0.0167 0.0166
Loa Loa (eye worm) RhoGEF domain-containing protein 0.006 0.0167 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Loa Loa (eye worm) PH domain-containing protein 0.006 0.0167 0.0167
Leishmania major hypothetical protein, conserved 0.0037 0.0084 0.0885
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0035 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus granulosus myotubularin protein 13 0.006 0.0167 0.0164
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0076 0.1213
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0185 0.0184
Toxoplasma gondii AtPH1 family protein 0.006 0.0167 0.2844
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0668
Trypanosoma brucei PH domain containing protein, putative 0.006 0.0167 0.1759
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0357 0.1246 0.1245
Entamoeba histolytica p21-activated kinase 0.0068 0.0198 0.1589
Loa Loa (eye worm) PXA domain-containing protein 0.0357 0.1246 0.1246
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0668
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0024 0.0189
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus multilocularis regulator of G protein signaling 7 0.0357 0.1246 0.1244
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.0783 0.0783
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.006 0.0167 0.0164
Echinococcus multilocularis Pleckstrin y 0.006 0.0167 0.0164
Echinococcus multilocularis calpain 0.0019 0.0019 0.0016
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Echinococcus multilocularis pdz domain containing protein 0.006 0.0167 0.0164
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0082 0.0214
Echinococcus granulosus axis inhibition protein axin 0.0357 0.1246 0.1244
Echinococcus granulosus SH2 motif 0.0029 0.0054 0.0052
Brugia malayi hypothetical protein 0.0214 0.0725 0.1886
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0035 0.0079 0.0637
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.006 0.0167 0.1339
Schistosoma mansoni protein tyrosine phosphatase 0.0049 0.0129 0.0128
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0049 0.0129 0.0128
Echinococcus granulosus tensin 0.0029 0.0054 0.0052
Brugia malayi hypothetical protein 0.0153 0.0505 0.1312
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0069 0.0068
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0207
Onchocerca volvulus Huntingtin homolog 0.0111 0.0352 0.3925
Echinococcus multilocularis signal transduction protein lnk realted 0.0029 0.0054 0.0052
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0084 0.0949
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0049 0.0129 0.0127
Onchocerca volvulus 0.0049 0.0129 0.1442
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0185 0.0185
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0459
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Echinococcus multilocularis hypothetical protein 0.0049 0.0129 0.0127
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0207 0.0207
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.0167 0.1759
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0032 0.0067 0.0066
Echinococcus granulosus oxysterol binding protein 9 0.006 0.0167 0.0164
Brugia malayi Muscleblind-like protein 0.017 0.0566 0.1472
Brugia malayi Cytohesin 3 0.006 0.0167 0.0433
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0171 0.0572 0.0571
Schistosoma mansoni regulator of G protein signaling 0.0357 0.1246 0.1245
Loa Loa (eye worm) hypothetical protein 0.0242 0.0829 0.0829
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0084 0.0673
Echinococcus granulosus regulator of G protein signaling 3 0.0357 0.1246 0.1244
Brugia malayi Bromodomain containing protein 0.0028 0.0054 0.014
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0068 0.0198 0.2088
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Brugia malayi beta-lactamase family protein 0.0037 0.0084 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0878
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0055 0.0055
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0019 0.0195
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0082 0.008
Plasmodium falciparum phd finger protein, putative 0.0028 0.0054 0.2572
Loa Loa (eye worm) latrophilin receptor protein 2 0.0077 0.0229 0.0229
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) oxysterol binding protein 0.006 0.0167 0.0167
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Trichomonas vaginalis centaurin gamma, putative 0.006 0.0167 0.1339
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0068 0.0198 0.1589
Trypanosoma cruzi kinesin, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0077 0.0229 0.0227
Loa Loa (eye worm) syntrophin-1 0.006 0.0167 0.0167
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Brugia malayi GTP-ase activating protein for Arf containing protein 0.006 0.0167 0.0433
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0357 0.1246 0.1244
Mycobacterium ulcerans hypothetical protein 0.0145 0.0476 1
Brugia malayi beta-lactamase 0.0037 0.0084 0.0218
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0084 0.0949
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0035 0.0079 0.0079
Onchocerca volvulus 0.0044 0.0109 0.1212
Brugia malayi latrophilin 2 splice variant baaae 0.0165 0.0551 0.1432
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0029 0.0054 0.0605
Echinococcus granulosus calpain A 0.0066 0.019 0.0188
Echinococcus granulosus lamin 0.0024 0.0039 0.0037
Onchocerca volvulus 0.0095 0.0296 0.3302
Schistosoma mansoni lamin 0.0024 0.0039 0.0038
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.019 0.0189
Entamoeba histolytica ARF GTPase activating protein, putative 0.006 0.0167 0.1339
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0084 0.0673
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0035 0.0459
Echinococcus multilocularis calpain 5 0.0019 0.0019 0.0016
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.019 0.0189
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0049 0.0129 0.0128
Schistosoma mansoni peptidase 0.0014 0.0002 0.0001
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.006 0.0167 0.1339
Trypanosoma brucei protein tyrosine phosphatase 1 0.0049 0.0129 0.1364
Echinococcus multilocularis Oxysterol binding protein 11 0.006 0.0167 0.0164
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1074 0.3847 1
Echinococcus multilocularis peregrin 0.0028 0.0054 0.0052
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0613 0.2176 0.2174
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus multilocularis tensin 0.0029 0.0054 0.0052
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0079 0.0637
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Echinococcus granulosus expressed conserved protein 0.0029 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0049 0.0129 0.0128
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0054 0.2572
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0049 0.0129 0.0127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.009
Loa Loa (eye worm) hypothetical protein 0.0153 0.0505 0.0505
Echinococcus granulosus axis inhibition protein axin 0.0357 0.1246 0.1244
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0035 0.0033
Onchocerca volvulus 0.006 0.0167 0.1859
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0054 0.0054
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Echinococcus granulosus lamin dm0 0.0024 0.0039 0.0037
Echinococcus granulosus tyrosine protein kinase ABL1 0.0032 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0111 0.0352 0.0352
Plasmodium vivax conserved Plasmodium protein, unknown function 0.006 0.0167 0.8394
Schistosoma mansoni oxysterol-binding protein 1 0.006 0.0167 0.0166
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Entamoeba histolytica hypothetical protein 0.006 0.0167 0.1339
Plasmodium vivax SET domain protein, putative 0.0035 0.0076 0.3714
Echinococcus granulosus tyrosine kinase 0.0032 0.0067 0.0065
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0668
Brugia malayi RNA binding protein 0.0065 0.0185 0.0482
Trypanosoma brucei glucosidase, putative 0.0037 0.0083 0.0878
Schistosoma mansoni ap endonuclease 0.0035 0.0079 0.0078
Schistosoma mansoni hypothetical protein 0.0171 0.0572 0.0571
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Schistosoma mansoni oxysterol-binding protein 1 0.006 0.0167 0.0166
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0111 0.0111
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Schistosoma mansoni dynamin 0.006 0.0167 0.0166
Schistosoma mansoni hypothetical protein 0.0077 0.0229 0.0227
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Echinococcus multilocularis rac serine:threonine kinase 0.0068 0.0198 0.0196
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0035 0.0079 0.0838
Schistosoma mansoni tensin 0.0029 0.0054 0.0053
Onchocerca volvulus 0.0029 0.0054 0.0605
Brugia malayi Ets-domain containing protein 0.0071 0.0207 0.0538
Echinococcus granulosus tar DNA binding protein 0.0065 0.0185 0.0183
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Echinococcus multilocularis NCK adaptor protein 0.0029 0.0054 0.0052
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1074 0.3847 0.3847
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0289 0.0287
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Echinococcus multilocularis expressed protein 0.0357 0.1246 0.1244
Brugia malayi Protein kinase domain containing protein 0.0032 0.0067 0.0174
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0009 0.0007
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0548 0.1424
Echinococcus multilocularis DCC interacting protein 13 beta 0.006 0.0167 0.0164
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0049 0.0129 0.1364
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.001 0.0017
Echinococcus multilocularis SH2 motif 0.0029 0.0054 0.0052
Trichomonas vaginalis protein transport protein sec7, putative 0.006 0.0167 0.1339
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0035 0.0278
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Brugia malayi Protein kinase domain containing protein 0.0032 0.0067 0.0174
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0049 0.0129 0.1038
Schistosoma mansoni growth factor receptor-bound protein 0.0029 0.0054 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Echinococcus multilocularis regulator of G protein signaling 0.0357 0.1246 0.1244
Onchocerca volvulus 0.0049 0.0129 0.1442
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0301 0.0782
Trichomonas vaginalis centaurin beta, putative 0.006 0.0167 0.1339
Schistosoma mansoni goodpasture antigen-binding protein 0.006 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0098 0.0096
Onchocerca volvulus 0.0049 0.0129 0.1442
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0013 0.0483
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0084 0.0885
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0029 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.0044 0.0111 0.0111
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.002 0.0207
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0049 0.0129 0.0129
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0068 0.0198 0.2088
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.019 0.0188
Schistosoma mansoni protein tyrosine phosphatase 0.0049 0.0129 0.0128
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0179 0.0178
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0025 0.004 0.004
Onchocerca volvulus Tyrosine kinase homolog 0.0172 0.0575 0.6408
Schistosoma mansoni z-protein (S1r protein) 0.0357 0.1246 0.1245
Echinococcus multilocularis GPCR, family 2 0.0077 0.0229 0.0226
Leishmania major hypothetical protein, conserved 0.006 0.0167 0.1759
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0044 0.0109 0.0282
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0068 0.0198 0.1589
Loa Loa (eye worm) AGC/AKT protein kinase 0.0068 0.0198 0.0198
Trichomonas vaginalis centaurin alpha, putative 0.006 0.0167 0.1339
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0054 0.0054
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.002 0.0019
Schistosoma mansoni zinc finger protein 0.006 0.0167 0.0166
Schistosoma mansoni dynamin 0.006 0.0167 0.0166
Schistosoma mansoni serine/threonine-protein kinase 0.0068 0.0198 0.0197
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0049 0.0129 0.0127
Brugia malayi hypothetical protein 0.0029 0.0054 0.0141
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.006 0.0167 0.0164
Brugia malayi GTP-ase activating protein for Arf containing protein 0.006 0.0167 0.0433
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0082 0.0869
Brugia malayi Variant SH3 domain containing protein 0.0088 0.027 0.0703
Onchocerca volvulus 0.0049 0.0129 0.1442
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Plasmodium vivax calpain, putative 0.0019 0.0019 0.0748
Echinococcus granulosus tyrosine protein kinase Srms 0.0032 0.0067 0.0065
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0019 0.0195
Schistosoma mansoni regulator of G protein signaling 0.0357 0.1246 0.1245
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0019 0.0017
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.0802 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0301 0.0301
Echinococcus granulosus Pleckstrin y 0.006 0.0167 0.0164
Echinococcus multilocularis growth factor receptor bound protein 2 0.0029 0.0054 0.0052
Echinococcus multilocularis dynamin 1 0.006 0.0167 0.0164
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.006 0.0167 0.1339
Echinococcus granulosus jumonji domain containing protein 0.004 0.0094 0.0092
Echinococcus multilocularis G protein coupled receptor kinase 1 0.2412 0.8705 0.8705
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.006 0.0167 0.0433
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0082 0.0869
Loa Loa (eye worm) hypothetical protein 0.0044 0.0111 0.0111
Brugia malayi Ets-domain containing protein 0.0071 0.0207 0.0538
Schistosoma mansoni ets-related 0.0215 0.0729 0.0728
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0717 0.2552 0.2552
Echinococcus multilocularis 0.0029 0.0054 0.0052
Loa Loa (eye worm) transcription factor SMAD2 0.0103 0.0325 0.0325
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0082 0.0869
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0049 0.0129 0.0336
Brugia malayi SH2 domain containing protein 0.0032 0.0067 0.0174
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0207
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Brugia malayi Latrophilin receptor protein 2 0.0077 0.0229 0.0594
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0054 0.0053
Brugia malayi TAR-binding protein 0.0065 0.0185 0.0482
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.006 0.0167 0.0164
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0301 0.0298
Echinococcus multilocularis Pleckstrin y 0.006 0.0167 0.0164
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0068 0.0198 0.2088
Onchocerca volvulus 0.0049 0.0129 0.1442
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0084 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus multilocularis geminin 0.0171 0.0572 0.057
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0878
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.002 0.014
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0037 0.0085 0.0685
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0068 0.0198 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0169 0.0565 1
Echinococcus granulosus tyrosine protein kinase shark 0.0032 0.0067 0.0065
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Echinococcus granulosus oxysterol binding protein 3 0.006 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Brugia malayi Fli-1 protein 0.0215 0.0729 0.1895
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0029 0.0054 0.0052
Echinococcus multilocularis survival motor neuron protein 1 0.0214 0.0725 0.0723
Echinococcus granulosus c src tyrosine kinase 0.0032 0.0067 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Entamoeba histolytica hypothetical protein 0.0357 0.1246 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.004 0.0565
Loa Loa (eye worm) hypothetical protein 0.0023 0.0035 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Entamoeba histolytica hypothetical protein 0.0068 0.0198 0.1589
Giardia lamblia PHD finger protein 15 0.0028 0.0054 0.3119
Trypanosoma brucei protein kinase, putative 0.0068 0.0198 0.2088
Schistosoma mansoni hypothetical protein 0.006 0.0167 0.0166
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.006 0.0167 0.1759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Brugia malayi Variant SH3 domain containing protein 0.006 0.0167 0.0433
Schistosoma mansoni tensin 0.0029 0.0054 0.0053
Echinococcus multilocularis 0.0049 0.0129 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0084 0.0949
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0009 0.0009
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0039 0.0038
Brugia malayi regulator of G-protein signaling egl-10 0.0357 0.1246 0.3238
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.2769 1 1
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.002 0.0017
Onchocerca volvulus 0.0049 0.0129 0.1442
Entamoeba histolytica protein kinase, putative 0.0068 0.0198 0.1589
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0084 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) hypothetical protein 0.006 0.017 0.017
Echinococcus multilocularis muscleblind protein 0.017 0.0566 0.0564
Brugia malayi Tyrosine-protein kinase abl-1 0.0032 0.0067 0.0174
Leishmania major mitochondrial DNA polymerase beta 0.0275 0.0948 1
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0668
Trichomonas vaginalis set domain proteins, putative 0.0261 0.0897 0.7199
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0019 0.0195
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.0167 0.1759
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Onchocerca volvulus 0.0049 0.0129 0.1442
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0083 0.0216
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0013 0.0061
Echinococcus granulosus Pleckstrin y 0.006 0.0167 0.0164
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.006 0.0167 0.0164
Loa Loa (eye worm) CXXC zinc finger family protein 0.0089 0.0273 0.0273
Onchocerca volvulus 0.0032 0.0067 0.0745
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Schistosoma mansoni axis inhibition protein axin 0.0357 0.1246 0.1245
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0029 0.0054 0.0052
Entamoeba histolytica protein kinase, putative 0.0027 0.005 0.0399
Loa Loa (eye worm) hypothetical protein 0.0088 0.027 0.027
Echinococcus granulosus SH2 motif 0.0029 0.0054 0.0052
Echinococcus multilocularis SH2 domain containing protein 7 0.0029 0.0054 0.0052
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0013 0.0483
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0049 0.0129 0.0127
Echinococcus multilocularis tyrosine protein kinase Abl 0.0032 0.0067 0.0065
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.006 0.0167 0.1339
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0548 0.0546
Treponema pallidum exodeoxyribonuclease (exoA) 0.0035 0.0079 0.5
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0613 0.2176 0.2175
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Echinococcus multilocularis calcium dependent secretion activator 1 0.006 0.0167 0.0164
Schistosoma mansoni protein tyrosine phosphatase 0.0049 0.0129 0.0128
Echinococcus granulosus dynamin 1 0.006 0.0167 0.0164
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0087 0.0226
Plasmodium falciparum PH domain-containing protein, putative 0.006 0.0167 0.8394
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0049 0.0129 0.1364
Echinococcus granulosus peregrin 0.0028 0.0054 0.0052
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Brugia malayi TBC domain containing protein 0.006 0.0167 0.0433
Brugia malayi Pleckstrin Homology Domain 0.006 0.0167 0.0433
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0357 0.1246 0.1246
Echinococcus multilocularis oxysterol binding protein 9 0.006 0.0167 0.0164
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.006 0.0167 0.1859
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Onchocerca volvulus 0.0049 0.0129 0.1442
Brugia malayi SH2 domain containing protein 0.0029 0.0054 0.0141
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0185 0.0184
Brugia malayi CXXC zinc finger family protein 0.0089 0.0273 0.0708
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Echinococcus multilocularis regulator of G protein signaling 7 0.0357 0.1246 0.1244
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0049 0.0129 0.0128
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0084 0.1524
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0082 0.0661
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.006 0.0167 0.0166
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0035 0.0079 0.0838
Toxoplasma gondii Oxysterol-binding protein 0.006 0.0167 0.2844
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Leishmania major kinesin, putative 0.0019 0.0019 0.0195
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0032 0.0067 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0056 0.0153 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Onchocerca volvulus 0.0032 0.0067 0.0745
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0076 0.0075
Onchocerca volvulus 0.0029 0.0054 0.0605
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Onchocerca volvulus 0.0049 0.0129 0.1442
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.002 0.014
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0056 0.0153 0.0151
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0054 0.0141
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0032 0.0067 0.0065
Echinococcus granulosus dna polymerase kappa 0.0019 0.002 0.0017
Brugia malayi beta-lactamase family protein 0.0037 0.0084 0.0218
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0219 0.0218
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0094 0.0092
Brugia malayi isocitrate dehydrogenase 0.0016 0.0009 0.0022
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus SH2 domain containing protein 7 0.0029 0.0054 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Leishmania major hypothetical protein, conserved 0.0025 0.004 0.0422
Onchocerca volvulus Protein melted homolog 0.006 0.0167 0.1859
Brugia malayi hypothetical protein 0.0357 0.1246 0.3238
Entamoeba histolytica hypothetical protein 0.006 0.0167 0.1339
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0185 0.0184
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Leishmania major DNA polymerase kappa, putative 0.0019 0.002 0.0207
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Schistosoma mansoni tensin-related 0.0029 0.0054 0.0053
Loa Loa (eye worm) cytohesin 3 0.006 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Echinococcus granulosus geminin 0.0171 0.0572 0.057
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0084 0.0885
Entamoeba histolytica hypothetical protein 0.006 0.0167 0.1339
Onchocerca volvulus 0.0049 0.0129 0.1442
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0035 0.0328
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0049 0.0129 0.0127
Brugia malayi Dynamin 0.006 0.0167 0.0433
Onchocerca volvulus 0.0049 0.0129 0.1442
Giardia lamblia Protein tyrosine phosphatase 0.0049 0.0129 1
Brugia malayi hypothetical protein 0.0016 0.0008 0.0022
Leishmania major folate/biopterin transporter, putative 0.0068 0.0198 0.2088
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0047 0.0122 0.1282
Toxoplasma gondii exonuclease III APE 0.0035 0.0079 0.1274
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Leishmania major DNA polymerase eta, putative 0.0019 0.002 0.0207
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0054 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Schistosoma mansoni serine/threonine protein kinase 0.2769 1 1
Echinococcus multilocularis muscleblind protein 1 0.017 0.0566 0.0564
Schistosoma mansoni growth factor receptor-bound protein 0.0029 0.0054 0.0053
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus granulosus pdz domain containing protein 0.006 0.0167 0.0164
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus granulosus DCC interacting protein 13 beta 0.006 0.0167 0.0164
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0084 0.0082
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Onchocerca volvulus 0.0032 0.0067 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.1074 0.3847 0.3846
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0094 0.0093
Echinococcus multilocularis cpg binding protein 0.0094 0.0291 0.0289
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0009 0.009
Brugia malayi Dynamin 0.006 0.0167 0.0433
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0077 0.0229 0.0594
Echinococcus granulosus muscleblind protein 0.017 0.0566 0.0564
Schistosoma mansoni hypothetical protein 0.0077 0.0229 0.0227
Trichomonas vaginalis alpha chimerin, putative 0.006 0.0167 0.1339
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0806 0.2876 0.2874
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0035 0.0365
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Schistosoma mansoni GTPase activating protein 0.0029 0.0054 0.0053
Brugia malayi regulator of G-protein signaling rgs-7 0.0357 0.1246 0.3238
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.006 0.0167 0.0164
Echinococcus granulosus dnaJ subfamily B 0.1263 0.4535 0.4534
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Brugia malayi Protein kinase domain containing protein 0.0032 0.0067 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Trichomonas vaginalis hypothetical protein 0.006 0.0167 0.1339
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0084 1
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0054 0.0052
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0019 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0075
Trichomonas vaginalis protein transport protein sec7, putative 0.006 0.0167 0.1339
Onchocerca volvulus Alhambra homolog 0.0028 0.0054 0.0601
Loa Loa (eye worm) TK/ABL protein kinase 0.0032 0.0067 0.0067
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.002 0.0136
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0049 0.0129 0.0336
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0054 0.0141
Echinococcus granulosus serine/threonine protein kinase 0.0068 0.0198 0.0196
Echinococcus granulosus GPCR family 2 0.0077 0.0229 0.0226
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Loa Loa (eye worm) RNA binding protein 0.0065 0.0185 0.0185
Loa Loa (eye worm) beta-lactamase 0.0037 0.0084 0.0084
Schistosoma mansoni ap endonuclease 0.0035 0.0079 0.0078
Brugia malayi Sex muscle abnormal protein 5 0.0029 0.0054 0.0141
Echinococcus multilocularis regulator of G protein signaling 3 0.0357 0.1246 0.1244
Echinococcus multilocularis SH2 motif 0.0029 0.0054 0.0052
Schistosoma mansoni nck2/grb4 0.0029 0.0054 0.0053
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0179 0.0179
Mycobacterium ulcerans hypothetical protein 0.0023 0.0035 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0035 0.0033
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0029 0.0054 0.0052
Schistosoma mansoni cpg binding protein 0.0094 0.0291 0.029
Loa Loa (eye worm) hypothetical protein 0.0111 0.0352 0.0352
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Onchocerca volvulus 0.0044 0.0111 0.1236
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0613 0.2176 0.2174
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0015 0.0005 0.0005
Echinococcus granulosus Pleckstrin y 0.006 0.0167 0.0164
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.004 0.1856
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0082 0.008
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.002 0.0051
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Schistosoma mansoni hypothetical protein 0.006 0.0167 0.0166
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Echinococcus multilocularis axis inhibition protein axin 0.0357 0.1246 0.1244
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0019 0.0149
Plasmodium falciparum calcium-dependent protein kinase 7 0.0068 0.0198 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0079 0.3889
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.001 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0039 0.0091 0.0958
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0806 0.2876 0.2874
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.0167 0.1339
Schistosoma mansoni hypothetical protein 0.0165 0.0551 0.055
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus multilocularis tyrosine protein kinase shark 0.0032 0.0067 0.0065
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.002 0.0158
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Schistosoma mansoni hypothetical protein 0.006 0.0167 0.0166
Entamoeba histolytica PH domain containing protein 0.006 0.0167 0.1339
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Brugia malayi Oxysterol-binding protein 0.006 0.0167 0.0433
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0068 0.0198 0.2088
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.006 0.0167 0.1339
Leishmania major protein kinase, putative 0.0068 0.0198 0.2088
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0068 0.0198 0.2088
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.006 0.0167 0.0167
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Schistosoma mansoni serine/threonine protein kinase 0.2769 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0024 0.0189
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0032 0.0067 0.0065
Brugia malayi protein-tyrosine kinase 0.0032 0.0067 0.0174
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0019 0.0016
Leishmania major tyrosine specific protein phosphatase, putative 0.0049 0.0129 0.1364
Schistosoma mansoni gabp alpha 0.0071 0.0207 0.0206
Brugia malayi hypothetical protein 0.0025 0.004 0.0104
Echinococcus granulosus suppressor of cytokine signaling 7 0.0029 0.0054 0.0052
Plasmodium falciparum oxysterol-binding protein, putative 0.006 0.0167 0.8394
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0068 0.0198 0.2088
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Echinococcus granulosus signal transduction protein lnk realted 0.0029 0.0054 0.0052
Schistosoma mansoni guanyl-nucleotide exchange factor 0.006 0.0167 0.0166
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0009 0.0006
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus multilocularis axis inhibition protein axin 0.0357 0.1246 0.1244
Echinococcus granulosus calpain 5 0.0019 0.0019 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0094 0.0094
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0029 0.0054 0.0053
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.002 0.0207
Echinococcus multilocularis Regulator of G protein signaling 20 0.0357 0.1246 0.1244
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Schistosoma mansoni DNA polymerase eta 0.0019 0.002 0.0019
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0084 0.0949
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0068 0.0198 0.2088
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0357 0.1246 0.1244
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0082 0.008
Entamoeba histolytica SH2 domain containing protein 0.0029 0.0054 0.0435
Echinococcus multilocularis lamin 0.0024 0.0039 0.0037
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0019 0.0017
Schistosoma mansoni suppressor of cytokine signaling 0.0029 0.0054 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.004 0.0422
Brugia malayi RhoGAP domain containing protein 0.0029 0.0054 0.0141
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0029 0.0054 0.0053
Leishmania major serine/threonine-protein kinase a, putative 0.0068 0.0198 0.2088
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0083 0.0083
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus regulator of G protein signaling 7 0.0357 0.1246 0.1244
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0185 0.0184
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.006 0.0167 0.1759
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0717 0.2552 0.2552
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0185 0.0183
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0029 0.0054 0.0054
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.006 0.0167 0.0164
Brugia malayi calpain 7 0.0019 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Onchocerca volvulus 0.0024 0.0039 0.0435
Schistosoma mansoni regulator of G protein signaling 0.0357 0.1246 0.1245
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0806 0.2876 0.2875
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0094 0.0092
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Echinococcus multilocularis regulator of G protein signaling 3 0.0357 0.1246 0.1244
Echinococcus multilocularis calpain A 0.0066 0.019 0.0188
Schistosoma mansoni cpg binding protein 0.0089 0.0273 0.0271
Trypanosoma cruzi NIMA-related kinase, putative 0.0068 0.0198 0.2088
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0082 0.008
Loa Loa (eye worm) uncoordinated protein 104 0.006 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0106 0.0337 0.0336
Brugia malayi Oxysterol binding protein 0.006 0.0167 0.0433
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0806 0.2876 0.2876
Schistosoma mansoni suppressor of cytokine signaling 0.0029 0.0054 0.0053
Toxoplasma gondii phosphatidylinositol transfer protein 0.006 0.0167 0.2844
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Brugia malayi intermediate filament protein 0.0024 0.0039 0.0101
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0032 0.0067 0.0065
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0077 0.0229 0.0226
Trypanosoma cruzi Protein kinase B 0.0068 0.0198 0.2088
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0009 0.0022
Echinococcus granulosus oxysterol binding protein 1 0.006 0.0167 0.0164
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.009
Echinococcus granulosus growth factor receptor bound protein 2 0.0029 0.0054 0.0052
Brugia malayi Pre-SET motif family protein 0.0229 0.0783 0.2035
Onchocerca volvulus 0.0049 0.0129 0.1442
Brugia malayi PXA domain containing protein 0.0357 0.1246 0.3238
Brugia malayi hypothetical protein 0.0106 0.0337 0.0876
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0459
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0019 0.0195
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.006 0.0167 0.0164
Brugia malayi probable spectrin beta chain 0.006 0.0167 0.0433
Loa Loa (eye worm) TK protein kinase 0.0032 0.0067 0.0067
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0076 0.0074
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0083 0.0668
Echinococcus granulosus tyrosine kinase 0.0032 0.0067 0.0065
Toxoplasma gondii ABC1 family protein 0.0037 0.0084 0.1354
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.001 0.0017
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0049 0.0129 0.0128
Echinococcus granulosus dna polymerase eta 0.0019 0.002 0.0017
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0029 0.0054 0.0053
Brugia malayi Calcitonin receptor-like protein seb-1 0.0242 0.0829 0.2155
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0084 0.1524
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0054 0.0052
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0717 0.2552 0.255
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.002 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0173 0.0578 0.1501
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.006 0.0167 0.8394
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0049 0.0129 0.0127
Plasmodium vivax PH domain containing protein 0.006 0.0167 0.8394
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Entamoeba histolytica hypothetical protein 0.0106 0.0337 0.2705
Echinococcus granulosus calpain 0.0019 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0049 0.0129 0.1364
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0029 0.0054 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0185 0.0184
Brugia malayi PHD-finger family protein 0.0014 0.0003 0.0007
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.002 0.0158
Brugia malayi PH domain containing protein 0.006 0.0167 0.0433
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0065 0.0062
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0049 0.0129 0.0127
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.002 0.0136
Schistosoma mansoni microtubule-associated protein tau 0.0697 0.2481 0.248
Loa Loa (eye worm) hypothetical protein 0.0214 0.0725 0.0725
Schistosoma mansoni hypothetical protein 0.0083 0.0251 0.0249
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0548 0.0548
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.2924 0.2922
Echinococcus granulosus beta 1 syntrophin 0.006 0.0167 0.0164
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0084 0.0082
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0613 0.2176 0.2174
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Schistosoma mansoni growth factor receptor-bound protein 0.006 0.0167 0.0166
Entamoeba histolytica PH domain containing protein kinase, putative 0.0068 0.0198 0.1589
Brugia malayi Plekhf2 protein 0.006 0.0167 0.0433
Echinococcus multilocularis oxysterol binding protein 1 0.006 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus multilocularis tensin 0.0029 0.0054 0.0052
Brugia malayi hypothetical protein 0.0049 0.0129 0.0336
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0082 0.0081
Schistosoma mansoni tyrosine kinase 0.0032 0.0067 0.0066
Schistosoma mansoni survival motor neuron protein 0.0044 0.0109 0.0108
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0049 0.0129 0.0127
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0054 0.0814
Loa Loa (eye worm) SH2 domain-containing protein 0.0029 0.0054 0.0054
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0301 0.03
Entamoeba histolytica hypothetical protein, conserved domain containing 0.006 0.0167 0.1339
Schistosoma mansoni vav2 0.0088 0.027 0.0269
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Onchocerca volvulus 0.0037 0.0084 0.0935
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0077 0.0229 0.0226
Brugia malayi MAX-1A 0.006 0.0167 0.0433
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0054 0.0814
Echinococcus granulosus expressed protein 0.0357 0.1246 0.1244
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.006 0.0167 0.0166
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0068 0.0198 0.2088
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0029 0.0054 0.0052
Echinococcus granulosus intermediate filament protein 0.0024 0.0039 0.0037
Onchocerca volvulus 0.0153 0.0505 0.5628
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0013 0.5
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0094 0.0093
Brugia malayi hypothetical protein 0.0049 0.0129 0.0336
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0068 0.0198 0.2088
Echinococcus granulosus Rho GTPase activating protein 24 0.006 0.0167 0.0164
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0029 0.0054 0.0052
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0039 0.0091 0.0958
Echinococcus multilocularis tyrosine protein kinase Srms 0.0032 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0068 0.0198 0.2088
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.0167 0.1759
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0082 0.0661
Toxoplasma gondii hypothetical protein 0.006 0.0167 0.2844
Mycobacterium tuberculosis Conserved protein 0.0037 0.0084 0.0949
Onchocerca volvulus 0.0049 0.0129 0.1442
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0035 0.0459
Echinococcus multilocularis beta 1 syntrophin 0.006 0.0167 0.0164
Mycobacterium tuberculosis Conserved protein 0.0037 0.0084 0.0949
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0029 0.0054 0.0605
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Brugia malayi calpain family protein 1 0.0063 0.0179 0.0465
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0717 0.2552 0.255
Onchocerca volvulus 0.0024 0.0039 0.0435
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0084 0.0885
Brugia malayi tRNA modification GTPase TrmE family protein 0.0029 0.0054 0.0141
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0009 0.009
Entamoeba histolytica hypothetical protein 0.0106 0.0337 0.2705
Loa Loa (eye worm) hypothetical protein 0.0165 0.0551 0.0551
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0548 0.0546
Echinococcus multilocularis lamin dm0 0.0024 0.0039 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.001 0.0017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Echinococcus granulosus regulator of G protein signaling 3 0.0357 0.1246 0.1244
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Entamoeba histolytica hypothetical protein 0.0106 0.0337 0.2705
Brugia malayi jmjC domain containing protein 0.0093 0.0289 0.0751
Brugia malayi Protein-tyrosine phosphatase 1 0.0049 0.0129 0.0336
Onchocerca volvulus 0.0049 0.0129 0.1442
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0301 0.0298
Onchocerca volvulus 0.0037 0.0084 0.0935
Brugia malayi Variant SH3 domain containing protein 0.0029 0.0054 0.0141
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0029 0.0054 0.0054
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0009 0.0235
Echinococcus granulosus NCK adaptor protein 0.0029 0.0054 0.0052
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0083 0.0878
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Echinococcus multilocularis oxysterol binding protein 3 0.006 0.0167 0.0164
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0049 0.0129 0.0336
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Echinococcus multilocularis tyrosine kinase 0.0032 0.0067 0.0065
Brugia malayi Protein kinase domain containing protein 0.0032 0.0067 0.0174
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0049 0.0129 0.0127
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0029 0.0054 0.0052
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0035 0.0079 0.5447
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Schistosoma mansoni axis inhibition protein axin 0.0357 0.1246 0.1245
Onchocerca volvulus 0.0023 0.0035 0.0386
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0032 0.0067 0.0065
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0668
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.006 0.0167 0.0164
Brugia malayi Uncoordinated protein 104 0.006 0.0167 0.0433
Schistosoma mansoni cpg binding protein 0.0094 0.0291 0.029
Brugia malayi SRC-1 0.0032 0.0067 0.0174
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0049 0.0129 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0357 0.1246 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0035 0.0079 0.5
Brugia malayi SH2 domain containing protein 0.0032 0.0067 0.0174
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0035 0.0079 0.0077
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0063 0.0179 0.0179
Echinococcus multilocularis Pleckstrin y 0.006 0.0167 0.0164
Schistosoma mansoni lamin 0.0024 0.0039 0.0038
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0076 0.0073
Loa Loa (eye worm) hypothetical protein 0.017 0.0566 0.0566
Entamoeba histolytica PH domain containing protein 0.006 0.0167 0.1339
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trichomonas vaginalis helicase, putative 0.002 0.0024 0.0189
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.013 0.0423 0.4458
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0242 0.0829 0.2155
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0035 0.0079 0.0838
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0032 0.0067 0.0537
Echinococcus granulosus tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0049 0.0129 0.0127
Entamoeba histolytica PH domain containing protein 0.006 0.0167 0.1339
Echinococcus granulosus Pleckstrin domain containing protein family B 0.006 0.0167 0.0164
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.002 0.0051
Brugia malayi hypothetical protein 0.0357 0.1246 0.3238
Onchocerca volvulus 0.0166 0.0552 0.6152
Onchocerca volvulus 0.006 0.0167 0.1859
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0083 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0668
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0039 0.0101
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0029 0.0054 0.0052
Trypanosoma brucei kinesin, putative 0.0019 0.0019 0.0195
Loa Loa (eye worm) Plekhf2 protein 0.006 0.0167 0.0167
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.0053
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.004 0.0422
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.0207
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0032 0.0067 0.0065
Schistosoma mansoni alpha-glucosidase 0.0142 0.0465 0.0464
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.002 0.0207
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0009 0.0006
Entamoeba histolytica hypothetical protein, conserved 0.006 0.0167 0.1339
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.0337 0.0335
Echinococcus multilocularis actin binding protein anillin 0.006 0.0167 0.0164
Brugia malayi Protein kinase domain containing protein 0.0032 0.0067 0.0174
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0056 0.0153 0.0151
Mycobacterium ulcerans hypothetical protein 0.0037 0.0084 0.1524
Echinococcus multilocularis myotubularin protein 13 0.006 0.0167 0.0164
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0024 0.0039 0.0039
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0082 0.5718
Schistosoma mansoni hypothetical protein 0.0077 0.0229 0.0227
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0049 0.0129 0.0129
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0032 0.0067 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0083 0.0668
Mycobacterium tuberculosis Conserved protein 0.0037 0.0084 0.0949
Leishmania major protein kinase, putative 0.0068 0.0198 0.2088
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0084 0.0673
Echinococcus granulosus pleckstrin y domain containing family A 0.006 0.0167 0.0164
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0357 0.1246 0.1245
Echinococcus granulosus tyrosine protein kinase Blk 0.0032 0.0067 0.0065
Trypanosoma cruzi PH domain containing protein, putative 0.006 0.0167 0.1759
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0039 0.0038
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0049 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0032 0.0067 0.0065
Schistosoma mansoni intermediate filament proteins 0.0024 0.0039 0.0038
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0049 0.0129 0.1038
Onchocerca volvulus 4.1 G protein, putative homolog 0.0049 0.0129 0.1442
Loa Loa (eye worm) hypothetical protein 0.006 0.0167 0.0167
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0275 0.0948 1
Loa Loa (eye worm) calpain 0.0019 0.0019 0.0019
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0049 0.0129 0.0127
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0035 0.0033
Loa Loa (eye worm) TK/FER protein kinase 0.0032 0.0067 0.0067
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0052 0.014 0.0137
Schistosoma mansoni centaurin alpha 0.006 0.0167 0.0166
Loa Loa (eye worm) STAT protein 0.0029 0.0054 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0049 0.0129 0.0127
Brugia malayi MH2 domain containing protein 0.0103 0.0325 0.0844
Trypanosoma brucei RNA helicase, putative 0.0083 0.0251 0.2643
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0029 0.0054 0.0054
Brugia malayi exodeoxyribonuclease III family protein 0.0035 0.0079 0.0206
Schistosoma mansoni alpha glucosidase 0.0037 0.0083 0.0082
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0079 0.3889
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0668
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0019 0.0195
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0035 0.0079 0.0077
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.006 0.0167 0.0164
Echinococcus multilocularis Ras associated and pleckstrin y 0.006 0.0167 0.0164
Loa Loa (eye worm) hypothetical protein 0.0037 0.0084 0.0084
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0055 0.0052
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.004 0.1856
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0084 0.0949
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.0207
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0035 0.0459
Leishmania major hypothetical protein, conserved 0.006 0.0167 0.1759
Entamoeba histolytica hypothetical protein 0.0357 0.1246 1
Onchocerca volvulus 0.0029 0.0054 0.0605
Brugia malayi Regulator of G protein signaling domain containing protein 0.0357 0.1246 0.3238
Brugia malayi hypothetical protein 0.006 0.0167 0.0433
Loa Loa (eye worm) calpain 5 0.0019 0.0019 0.0019
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0049 0.0129 0.0128
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.006 0.0167 0.8394
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0129 0.0127
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0129
Brugia malayi hypothetical protein 0.0111 0.0352 0.0915
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.006 0.0167 0.1759
Trichomonas vaginalis AGC family protein kinase 0.0068 0.0198 0.1589
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0035 0.009
Onchocerca volvulus 0.0035 0.0076 0.0848
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0275 0.0948 1
Echinococcus granulosus suppressor of cytokine signaling 6 0.0029 0.0054 0.0052
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0068 0.0198 0.2088
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0024 0.0189
Onchocerca volvulus 0.0032 0.0067 0.0745
Echinococcus multilocularis beta adrenergic receptor kinase 0.2769 1 1
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.006 0.0167 0.8394
Entamoeba histolytica protein kinase, putative 0.0037 0.0085 0.0685
Mycobacterium tuberculosis Conserved hypothetical protein 0.0145 0.0476 0.5892
Echinococcus multilocularis SHC transforming protein 3 0.0029 0.0054 0.0052
Entamoeba histolytica hypothetical protein 0.006 0.0167 0.1339
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0035 0.0079 0.0893
Loa Loa (eye worm) hypothetical protein 0.0028 0.0054 0.0054
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0049 0.0129 0.1364
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.002 0.0019
Plasmodium vivax hypothetical protein, conserved 0.006 0.0167 0.8394
Schistosoma mansoni hypothetical protein 0.1263 0.4535 0.4535
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0054
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0032 0.0067 0.0065
Brugia malayi PHD-finger family protein 0.0028 0.0054 0.014
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0242 0.0829 0.0829
Loa Loa (eye worm) RGS-3 protein 0.0357 0.1246 0.1246
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0185 0.0185
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.006 0.0167 0.1339
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.006 0.0167 0.8394
Echinococcus multilocularis dnaJ subfamily B 0.1263 0.4535 0.4534
Onchocerca volvulus Putative zinc finger protein 0.006 0.0167 0.1859
Loa Loa (eye worm) hypothetical protein 0.0357 0.1246 0.1246
Schistosoma mansoni zinc finger protein 0.006 0.0167 0.0166
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0049 0.0129 0.1038
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0055 0.0052
Schistosoma mansoni shc transforming protein 0.0029 0.0054 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0167 0.1339
Trypanosoma cruzi hypothetical protein 0.006 0.0167 0.1759
Onchocerca volvulus 0.0049 0.0129 0.1442
Schistosoma mansoni rhogef and pleckstrin domain protein 0.006 0.0167 0.0166
Echinococcus granulosus calcium dependent secretion activator 1 0.006 0.0167 0.0164

Activities

Activity type Activity value Assay description Source Reference
DIZ (functional) Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition at 1000 ug/mL after 24 hrs by disk diffusion assay ChEMBL. 24044873
IZ (functional) = 6.5 mm Antibacterial activity against Escherichia coli ATCC 8099 assessed as growth inhibition at 1000 ug/mL after 24 hrs by disk diffusion assay ChEMBL. 24044873

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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