Detailed information for compound 1789856

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 191.225 | Formula: C8H17NO4
  • H donors: 4 H acceptors: 4 LogP: -0.97 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1[C@@H](O)C[C@H]([C@@H](N1C)CO)O
  • InChi: 1S/C8H17NO4/c1-9-5(3-10)7(12)2-8(13)6(9)4-11/h5-8,10-13H,2-4H2,1H3/t5-,6+,7+,8-
  • InChiKey: CDGKBGOAPNEEAH-SOSBWXJGSA-N  


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Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus protein tyrosine kinase 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Leishmania major protein kinase, putative 0.0043 0.0101 0.0916
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0043 0.0101 0.0102
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0074 0.0075
Echinococcus multilocularis protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) RGC/RGC protein kinase 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.2256 0.9866 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.004 0.0091 0.0563
Brugia malayi Raf kinase 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2256 0.9866 1
Brugia malayi bone morphogenetic protein type 1 receptor 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0036 0.0074 0.0075
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0043 0.0101 0.0086
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0101 0.0916
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0016 0.0017
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0036 0.0074 0.0075
Echinococcus multilocularis heat shock protein 70 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis transfer RNA-Thr 0.0036 0.0074 0.0075
Echinococcus multilocularis FL cytokine receptor 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase shark 0.0036 0.0074 0.0075
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0036 0.0074 0.0074
Echinococcus multilocularis ephrin type A receptor 4 A 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus protein kinase 0.0036 0.0074 0.0059
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0036 0.0074 0.0059
Plasmodium falciparum glycogen synthase kinase 3 0.0103 0.0366 1
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0036 0.0074 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi hypothetical protein 0.0036 0.0074 0.0075
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Brugia malayi C-terminal src kinase protein 1 0.0036 0.0074 0.0075
Schistosoma mansoni ephrin receptor 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0074 0.0059
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0036 0.0074 0.0059
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Schistosoma mansoni protein kinase 0.004 0.0091 0.0091
Schistosoma mansoni protein kinase 0.0043 0.0101 0.0101
Brugia malayi SH2 domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0036 0.0074 0.0059
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0036 0.0074 0.0059
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2256 0.9866 1
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0074 0.0075
Echinococcus multilocularis raf serine:threonine protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/INSR protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus protein kinase shaggy 0.0103 0.0366 0.0355
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0103 0.0366 0.0366
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0036 0.0074 0.0059
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi Receptor family ligand binding region containing protein 0.004 0.0091 0.0092
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Echinococcus granulosus tyrosine kinase 0.004 0.0091 0.0075
Echinococcus multilocularis kinase suppressor of Ras 1 0.0036 0.0074 0.0075
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Echinococcus granulosus activated cdc42 kinase 1 0.0036 0.0074 0.0059
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0016 0.0017
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0074 0.0075
Loa Loa (eye worm) SRC-1 0.0036 0.0074 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0043 0.0101 0.0916
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0036 0.0074 0.0075
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0036 0.0074 0.0059
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase csk 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis activin receptor type 0.0043 0.0101 0.0102
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus natriuretic peptide receptor 1 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/ACK protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis c src tyrosine kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus epidermal growth factor receptor 0.0036 0.0074 0.0059
Echinococcus multilocularis tyrosine protein kinase Abl 0.0036 0.0074 0.0075
Schistosoma mansoni ephrin receptor 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus integrin linked protein kinase 0.0036 0.0074 0.0059
Echinococcus granulosus tyrosine protein kinase HCK 0.0036 0.0074 0.0059
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0036 0.0074 0.0075
Echinococcus multilocularis epidermal growth factor receptor 0.0036 0.0074 0.0075
Brugia malayi hypothetical protein 0.0036 0.0074 0.0075
Echinococcus granulosus kinase suppressor of Ras 1 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0091 0.0092
Brugia malayi protein-tyrosine kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus activin receptor type 0.0043 0.0101 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus insulin receptor 0.0036 0.0074 0.0059
Echinococcus multilocularis tyrosine kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Brugia malayi ephrin receptor 1 precursor 0.0036 0.0074 0.0075
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0091 0.0092
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0043 0.0101 0.0916
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0036 0.0074 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0366 1
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0101 0.0916
Schistosoma mansoni tyrosine protein kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine kinase 0.004 0.0091 0.0092
Echinococcus granulosus receptor type guanylyl cyclase 0.004 0.0091 0.0075
Echinococcus granulosus epidermal growth factor receptor 0.0036 0.0074 0.0059
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase shark 0.0036 0.0074 0.0059
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0036 0.0074 0.0059
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0074 0.0059
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0036 0.0074 0.0075
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0074 0.0075
Brugia malayi SRC-1 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0074 0.0075
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus tyrosine protein kinase pr2 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.2256 0.9866 1
Schistosoma mansoni glutamate receptor NMDA 0.0023 0.0016 0.0016
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0036 0.0074 0.0075
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.0366 1
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/ROR protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FAK protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Giardia lamblia Kinase, CMGC GSK 0.0103 0.0366 1
Echinococcus multilocularis activated cdc42 kinase 1 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni hypothetical protein 0.0036 0.0074 0.0074
Schistosoma mansoni protein kinase 0.0043 0.0101 0.0101
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0074 0.0059
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Brugia malayi hypothetical protein 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Srms 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Trypanosoma brucei protein kinase, putative 0.0103 0.0366 1
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis protein kinase shaggy 0.0103 0.0366 0.0371
Loa Loa (eye worm) TK/ALK protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus glutamate NMDA receptor subunit 0.0074 0.0238 0.0225
Schistosoma mansoni tyrosine kinase 0.004 0.0091 0.0091
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.225 0.9839 0.9973
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Lyn 0.0043 0.0101 0.0086
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0023 0.0016 0.0017
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0074 0.0059
Schistosoma mansoni serine/threonine RGC 0.0036 0.0074 0.0074
Brugia malayi Tyrosine-protein kinase abl-1 0.0036 0.0074 0.0075
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0103 0.0366 1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0036 0.0074 0.0059
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK/ABL protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus c src tyrosine kinase 0.0036 0.0074 0.0059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0016 0.0017
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.004 0.0091 0.0091
Loa Loa (eye worm) RGC/RGC protein kinase 0.004 0.0091 0.0092
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0036 0.0074 0.0075
Plasmodium vivax glycogen synthase kinase 3, putative 0.0103 0.0366 1
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0036 0.0074 0.0075
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0036 0.0074 0.0074
Brugia malayi intracellular kinase 0.0103 0.0366 0.0371
Entamoeba histolytica protein kinase domain containing protein 0.0103 0.0366 1
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi SH2 domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase HCK 0.0036 0.0074 0.0075
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0103 0.0366 0.0355
Schistosoma mansoni protein tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0036 0.0074 0.0059
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0043 0.0101 0.0916
Loa Loa (eye worm) serine/threonine protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.004 0.0091 0.0092
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Onchocerca volvulus 0.004 0.0091 0.0563
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0036 0.0074 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075
Echinococcus multilocularis protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0023 0.0016 0.0017
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0074 0.0059
Brugia malayi Tyrosine-protein kinase PR2 0.0036 0.0074 0.0075
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Onchocerca volvulus 0.0103 0.0366 1
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Brugia malayi integrin-linked kinase 0.0036 0.0074 0.0075
Plasmodium falciparum protein kinase, putative 0.0043 0.0101 0.0916
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0074 0.0238 0.0242
Echinococcus granulosus activated cdc42 kinase 1 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Schistosoma mansoni protein kinase 0.0043 0.0101 0.0101
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus fibroblast growth factor receptor 4 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi Guanylyl cyclase protein 23 0.004 0.0091 0.0092
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0036 0.0074 0.0075
Loa Loa (eye worm) protein kinase domain-containing protein 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/RYK protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0036 0.0074 0.0075
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0103 0.0366 0.0371
Echinococcus granulosus raf serine:threonine protein kinase 0.0036 0.0074 0.0059
Brugia malayi Furin-like cysteine rich region family protein 0.0036 0.0074 0.0075
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0036 0.0074 0.0059
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0036 0.0074 0.0075
Echinococcus multilocularis epidermal growth factor receptor 0.0036 0.0074 0.0075
Trypanosoma brucei protein kinase, putative 0.0043 0.0101 0.0916
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis natriuretic peptide receptor 1 0.0036 0.0074 0.0075
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0103 0.0366 0.0371
Echinococcus granulosus tyrosine protein kinase csk 0.0036 0.0074 0.0059
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0103 0.0366 0.0371
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0074 0.0075
Echinococcus granulosus retinal guanylyl cyclase 2 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK/EGFR protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis receptor type guanylyl cyclase 0.004 0.0091 0.0092
Giardia lamblia Kinase, CMGC GSK 0.0103 0.0366 1
Loa Loa (eye worm) hypothetical protein 0.225 0.9839 0.9973
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0074 0.0074
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0074 0.0059
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase pr2 0.0036 0.0074 0.0075
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/Met protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine kinase 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Entamoeba histolytica protein kinase, putative 0.0103 0.0366 1
Echinococcus multilocularis integrin linked protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase ABL1 0.0036 0.0074 0.0059
Echinococcus multilocularis protein tyrosine kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK/DDR protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus tyrosine protein kinase Src64B 0.0036 0.0074 0.0059
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK protein kinase 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0103 0.0366 1
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus multilocularis protein KINase family member (kin 25) 0.0036 0.0074 0.0075
Brugia malayi Protein kinase domain containing protein 0.0036 0.0074 0.0075
Echinococcus multilocularis insulin receptor 0.0036 0.0074 0.0075
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Schistosoma mansoni protein kinase 0.0036 0.0074 0.0074
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0103 0.0366 1
Loa Loa (eye worm) TK/EPH protein kinase 0.0036 0.0074 0.0075
Loa Loa (eye worm) TK/CSK protein kinase 0.0036 0.0074 0.0075
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0036 0.0074 0.0059
Schistosoma mansoni glutamate receptor NMDA 0.0074 0.0238 0.0238
Echinococcus granulosus ephrin type A receptor 4 A 0.0036 0.0074 0.0059
Echinococcus granulosus tyrosine kinase 0.0036 0.0074 0.0059
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Echinococcus granulosus tyrosine protein kinase 0.0036 0.0074 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0366 1
Schistosoma mansoni tyrosine kinase 0.0036 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0036 0.0074 0.0075

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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