Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2829 | 0.9828 | 0.9828 |
Giardia lamblia | Hypothetical protein | 0.1698 | 0.5831 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0089 | 0.0089 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0049 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.1698 | 0.5831 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0074 | 0.0089 | 0.0089 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.2829 | 0.9828 | 0.9828 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0089 | 0.0089 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2878 | 1 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase PGMII | 0.0049 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2878 | 1 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2878 | 1 | 1 |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase MutT1 | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0049 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0074 | 0.0089 | 0.0089 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.2829 | 0.9828 | 0.9828 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0089 | 0.0089 |
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0049 | 0 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Treponema pallidum | phosphoglyceromutase | 0.0049 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1228 | 0.4169 | 0.4169 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0049 | 0 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0074 | 0.0089 | 0.0089 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | PE-PGRS family protein PE_PGRS11 | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.165 | 0.566 | 0.566 |
Brugia malayi | RNA binding protein | 0.0074 | 0.0089 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0049 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqD | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0074 | 0.0089 | 0.0089 |
Mycobacterium tuberculosis | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0049 | 0 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.1698 | 0.5831 | 0.5 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0074 | 0.0089 | 0.0089 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.2829 | 0.9828 | 0.9828 |
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Glucosyl-3-phosphoglycerate phosphatase GpgP | 0.0049 | 0 | 0.5 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0049 | 0 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1228 | 0.4169 | 0.4169 |
Brugia malayi | TAR-binding protein | 0.0074 | 0.0089 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0049 | 0 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.2878 | 1 | 1 |
Onchocerca volvulus | 0.2878 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.2878 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2878 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2829 | 0.9828 | 0.9828 |
Loa Loa (eye worm) | TAR-binding protein | 0.0074 | 0.0089 | 0.0089 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0942 | 0.3159 | 0.3159 |
Toxoplasma gondii | phosphoglycerate mutase family protein | 0.0049 | 0 | 0.5 |
Toxoplasma gondii | phosphoglycerate mutase | 0.0049 | 0 | 0.5 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.1698 | 0.5831 | 1 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0049 | 0 | 0.5 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.1698 | 0.5831 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1228 | 0.4169 | 0.4169 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0049 | 0 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0049 | 0 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1228 | 0.4169 | 0.4169 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0074 | 0.0089 | 1 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0049 | 0 | 0.5 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.2878 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.