Detailed information for compound 1792909

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 383.57 | Formula: C24H37N3O
  • H donors: 1 H acceptors: 1 LogP: 4.86 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1C(C1(C)C)(C)C)Nc1ccc(cc1C)N1CCC(C1)N1CCCC1C
  • InChi: 1S/C24H37N3O/c1-16-14-18(26-13-11-19(15-26)27-12-7-8-17(27)2)9-10-20(16)25-22(28)21-23(3,4)24(21,5)6/h9-10,14,17,19,21H,7-8,11-13,15H2,1-6H3,(H,25,28)
  • InChiKey: CJJRTJUBMZIMQU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Macaca mulatta Histamine receptor H3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) hypothetical protein Histamine receptor H3   445 aa 385 aa 23.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phosphoglycerate mutase, putative 0.004 0.0105 0.0813
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.009
Entamoeba histolytica hypothetical protein 0.0026 0.0046 0.0078
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.004 0.0105 0.0068
Leishmania major hypothetical protein, unknown function 0.004 0.0105 0.0105
Toxoplasma gondii phosphoglycerate mutase PGMII 0.004 0.0105 0.1707
Toxoplasma gondii phosphoglycerate mutase family protein 0.004 0.0105 0.1707
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0032 0.007 0.0504
Echinococcus multilocularis transcription factor btf3 0.0026 0.0046 0.0039
Onchocerca volvulus 0.0062 0.0197 0.0178
Toxoplasma gondii HEAT repeat-containing protein 0.0042 0.0112 0.181
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1409 0.5871 1
Loa Loa (eye worm) hypothetical protein 0.0096 0.0338 0.0332
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0065 0.0028
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0128 0.099
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.0616 0.061
Toxoplasma gondii phosphoglycerate mutase family protein 0.004 0.0105 0.1707
Mycobacterium leprae conserved hypothetical protein 0.004 0.0105 0.6423
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0128 0.0474 0.3397
Echinococcus granulosus chromobox protein 1 0.0046 0.0128 0.0121
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.0013
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0024 0.0037 0.0064
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0128 0.0474 0.0467
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0091 0.0319 0.0312
Mycobacterium leprae Possible phosphoglycerate mutase 0.004 0.0105 0.6423
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0474 0.0807
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0068
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0107 0.0386 0.0387
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0032 0.007 0.012
Brugia malayi RNA, U transporter 1 0.0119 0.0436 0.1914
Trichomonas vaginalis phosphoglycerate mutase, putative 0.004 0.0105 0.0813
Leishmania major DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Schistosoma mansoni polycystin 1-related 0.007 0.0231 0.0224
Trichomonas vaginalis DNA polymerase eta, putative 0.0028 0.0053 0.0411
Schistosoma mansoni hypothetical protein 0.0081 0.0275 0.0268
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0026 0.0006
Leishmania major DNA polymerase eta, putative 0.0065 0.0209 0.0209
Mycobacterium ulcerans acid phosphatase 0.004 0.0105 0.0179
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0128 0.0091
Loa Loa (eye worm) hypothetical protein 0.007 0.0231 0.0224
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0026 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.0024 0.0037 0.0031
Echinococcus multilocularis L aminoadipate semialdehyde 0.0055 0.0165 0.0159
Echinococcus multilocularis dna polymerase kappa 0.0028 0.0053 0.0047
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0026 0.0019
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0355 0.0348
Schistosoma mansoni coup transcription factor 0.0021 0.0026 0.0019
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0355 0.0348
Toxoplasma gondii phosphoglycerate mutase 0.004 0.0105 0.1707
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0032 0.007 0.012
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0046 0.0008
Trypanosoma brucei cytochrome P450, putative 0.005 0.0148 0.0148
Schistosoma mansoni hypothetical protein 0.0096 0.0338 0.0331
Loa Loa (eye worm) hypothetical protein 0.0177 0.0681 0.0675
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0031 0.0065 0.1162
Mycobacterium tuberculosis Probable lipase LipD 0.0054 0.0164 0.1174
Echinococcus granulosus L aminoadipate semialdehyde 0.0055 0.0165 0.0159
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.2388 0.9993 0.9993
Leishmania major cytochrome p450-like protein 0.005 0.0148 0.0148
Leishmania major phosphoglycerate mutase, putative 0.004 0.0105 0.0105
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2347 0.9823 0.983
Echinococcus granulosus smad 0.0033 0.0073 0.0067
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0073 0.0067
Onchocerca volvulus 0.0082 0.0282 0.0263
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0028 0.0052 0.0032
Onchocerca volvulus 0.007 0.0231 0.0211
Brugia malayi acetyltransferase, GNAT family protein 0.0549 0.225 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0053 0.0016
Leishmania major hypothetical protein, conserved 0.004 0.0105 0.0105
Mycobacterium ulcerans lipase LipD 0.0054 0.0164 0.0279
Loa Loa (eye worm) hypothetical protein 0.0302 0.1208 0.1203
Mycobacterium tuberculosis Conserved protein 0.0054 0.0164 0.1174
Echinococcus granulosus lipoxygenase domain containing protein 0.007 0.0231 0.0224
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.004 0.0105 0.0179
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Echinococcus granulosus lamin dm0 0.0082 0.0282 0.0276
Mycobacterium ulcerans phosphoglyceromutase 0.004 0.0105 0.0179
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0037 0.003
Schistosoma mansoni hypothetical protein 0.0032 0.007 0.0063
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.1019 0.4227 0.423
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0026 0.0019
Loa Loa (eye worm) phosphoglycerate mutase 0.004 0.0105 0.0098
Toxoplasma gondii ABC1 family protein 0.0054 0.0164 0.2657
Mycobacterium leprae probable isochorismate synthase EntC 0.004 0.0105 0.6423
Brugia malayi ecdysteroid receptor 0.0021 0.0026 0.0084
Loa Loa (eye worm) beta-lactamase 0.0054 0.0164 0.0157
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0032 0.007 0.007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0096 0.0338 0.0332
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0346 0.1394 1
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.004 0.0105 0.0105
Schistosoma mansoni lipoxygenase 0.0281 0.1121 0.1115
Onchocerca volvulus 0.031 0.1239 0.1223
Echinococcus granulosus snurportin 1 0.0446 0.1816 0.1811
Trypanosoma cruzi phosphoglycerate mutase, putative 0.004 0.0105 0.0068
Mycobacterium tuberculosis Conserved protein 0.004 0.0105 0.0754
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0022 0.0027 0.0192
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0026 0.0201
Mycobacterium tuberculosis Conserved protein 0.0054 0.0164 0.1174
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0068
Echinococcus multilocularis dnaJ subfamily B 0.0886 0.3666 0.3662
Plasmodium vivax phosphoglycerate mutase, putative 0.004 0.0105 0.1707
Echinococcus multilocularis peregrin 0.0035 0.0084 0.0077
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0112 0.0408 0.0401
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0069 0.0032
Echinococcus granulosus Polycystic kidney disease protein 0.007 0.0231 0.0224
Brugia malayi Heterochromatin protein 1 0.0046 0.0128 0.054
Brugia malayi MH1 domain containing protein 0.0033 0.0073 0.0296
Schistosoma mansoni transcription factor btf3 0.0026 0.0046 0.0039
Loa Loa (eye worm) doublecortin family protein 0.007 0.0231 0.0224
Mycobacterium tuberculosis Probable esterase LipL 0.0054 0.0164 0.1174
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0136 0.0129
Schistosoma mansoni lipoxygenase 0.0155 0.0589 0.0582
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0024 0.0037 0.0064
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.007 0.0033
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0022 0.0027 0.1636
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0031 0.0065 0.0058
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0032 0.007 0.0504
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0032 0.007 0.007
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0026 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0026 0.0019
Echinococcus multilocularis dna polymerase eta 0.0065 0.0209 0.0202
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.004 0.0105 0.0754
Mycobacterium ulcerans esterase/lipase LipP 0.0054 0.0164 0.0279
Brugia malayi Pre-SET motif family protein 0.0042 0.0111 0.0464
Schistosoma mansoni lozenge 0.0039 0.0099 0.0092
Echinococcus granulosus dnaJ subfamily B 0.0886 0.3666 0.3662
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0027 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0012 0.009
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0046 0.0741
Brugia malayi jmjC domain containing protein 0.003 0.0062 0.0244
Trypanosoma cruzi glycerolphosphate mutase, putative 0.004 0.0105 0.0068
Onchocerca volvulus Protein UBASH3A homolog 0.004 0.0105 0.0085
Echinococcus multilocularis chromobox protein 1 0.0046 0.0128 0.0121
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0042 0.0111 0.0105
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.004 0.0105 0.6423
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0032 0.007 0.0033
Schistosoma mansoni smad1 5 8 and 0.0033 0.0073 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0164 0.1267
Echinococcus granulosus lamin 0.0082 0.0282 0.0276
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.004 0.0105 0.6423
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0226 0.0888 0.0889
Loa Loa (eye worm) hypothetical protein 0.0315 0.1261 0.1256
Echinococcus multilocularis neuropeptide s receptor 0.0654 0.2692 0.2687
Schistosoma mansoni importin beta-1 0.0042 0.0112 0.0105
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Brugia malayi MH2 domain containing protein 0.0033 0.0073 0.0296
Echinococcus multilocularis beta LACTamase domain containing family member 0.0054 0.0164 0.0157
Onchocerca volvulus 0.0055 0.0165 0.0146
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0098
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0032 0.0069 0.0032
Schistosoma mansoni DNA polymerase eta 0.0065 0.0209 0.0202
Trypanosoma brucei glycerolphosphate mutase, putative 0.004 0.0105 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0164 0.0127
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0026 0.0006
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0474 0.0467
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0091 0.0319 0.0542
Schistosoma mansoni microtubule-associated protein tau 0.2389 1 1
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Mycobacterium tuberculosis Conserved hypothetical protein 0.0028 0.0053 0.0382
Echinococcus granulosus survival motor neuron protein 1 0.0177 0.0681 0.0675
Trichomonas vaginalis bromodomain-containing protein, putative 0.0162 0.0616 0.4772
Leishmania major mitochondrial DNA polymerase beta 0.0226 0.0888 0.0889
Loa Loa (eye worm) hypothetical protein 0.031 0.1239 0.1234
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Brugia malayi Inositol-1 0.0024 0.0037 0.0136
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0032 0.007 0.0504
Echinococcus multilocularis survival motor neuron protein 1 0.0177 0.0681 0.0675
Toxoplasma gondii aldehyde dehydrogenase 0.0128 0.0474 0.7689
Echinococcus multilocularis importin subunit beta 1 0.0042 0.0112 0.0105
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0032 0.007 0.012
Brugia malayi nuclear hormone receptor 0.0021 0.0026 0.0084
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0054 0.0164 0.1174
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0055 0.0165 0.0158
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0032 0.007 0.012
Mycobacterium tuberculosis Possible hydrolase MutT1 0.004 0.0105 0.0754
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0027 0.0444
Mycobacterium tuberculosis Conserved protein 0.0054 0.0164 0.1174
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0148 0.0141
Echinococcus granulosus Smad4 0.0033 0.0073 0.0067
Mycobacterium leprae Conserved hypothetical protein 0.0032 0.007 0.4292
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.0111 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0026 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Plasmodium falciparum histone acetyltransferase GCN5 0.0148 0.0559 1
Brugia malayi hypothetical protein 0.0177 0.0681 0.3007
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0355 0.0348
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0026 0.0019
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0162 0.0616 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0031 0.0065 0.1055
Brugia malayi hypothetical protein 0.0178 0.0686 0.3026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0276 0.0269
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0026 0.0019
Schistosoma mansoni cpg binding protein 0.0066 0.0212 0.0205
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0026 0.0019
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0032 0.007 0.012
Schistosoma mansoni inositol monophosphatase 0.0024 0.0037 0.0031
Echinococcus multilocularis chromobox protein 1 0.0046 0.0128 0.0121
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0026 0.0019
Echinococcus granulosus transcription factor Dp 1 0.0053 0.0157 0.0151
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0028 0.0053 0.0411
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0125 0.0118
Trypanosoma brucei hypothetical protein, conserved 0.0054 0.0164 0.0164
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0164 0.1267
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0162 0.0616 0.4772
Brugia malayi beta-NAC-like protein 0.0026 0.0046 0.0172
Mycobacterium ulcerans hydrolase MutT1 0.004 0.0105 0.0179
Schistosoma mansoni hypothetical protein 0.0096 0.0338 0.0331
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0026 0.0019
Brugia malayi Bromodomain containing protein 0.0035 0.0084 0.0344
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0091 0.0319 0.0282
Mycobacterium leprae conserved hypothetical protein 0.004 0.0105 0.6423
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0053 0.0016
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0046 0.0128 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0026 0.0084
Echinococcus multilocularis GPCR, family 2 0.0096 0.0338 0.0332
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0355 0.0348
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.004 0.0105 0.0099
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0091 0.0319 0.0312
Echinococcus granulosus cytochrome P450 2K1 0.0032 0.007 0.0064
Brugia malayi MH1 domain containing protein 0.0033 0.0073 0.0296
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.005 0.0148 0.0252
Brugia malayi MH2 domain containing protein 0.0481 0.1961 0.8712
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0164 0.0127
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.004 0.0105 0.0754
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.004 0.0105 0.0754
Loa Loa (eye worm) inositol-1 0.0024 0.0037 0.0031
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0037 0.0288
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0474 0.0807
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0023 0.0016
Brugia malayi Cytochrome P450 family protein 0.005 0.0148 0.0627
Mycobacterium ulcerans beta-lactamase 0.0054 0.0164 0.0279
Schistosoma mansoni inositol monophosphatase 0.0024 0.0037 0.0031
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0046 0.0741
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0096 0.0338 0.1477
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0026 0.0019
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0024 0.0037 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0026 0.0019
Schistosoma mansoni hypothetical protein 0.007 0.0231 0.0224
Toxoplasma gondii phosphoglycerate mutase family protein 0.004 0.0105 0.1707
Mycobacterium ulcerans hypothetical protein 0.1409 0.5871 1
Onchocerca volvulus 0.0021 0.0026 0.0006
Loa Loa (eye worm) hypothetical protein 0.031 0.1239 0.1234
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0032 0.007 0.0504
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0026 0.0043 0.0023
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Brugia malayi Muscleblind-like protein 0.0315 0.1261 0.5592
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0055 0.0165 0.0706
Onchocerca volvulus Protein UBASH3A homolog 0.004 0.0105 0.0085
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.004 0.0105 0.0105
Leishmania major cytochrome p450-like protein 0.0032 0.007 0.007
Echinococcus granulosus GTP binding nuclear protein Ran 0.0031 0.0065 0.0058
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0031 0.0065 0.0065
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0032 0.007 0.012
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0032 0.007 0.0504
Echinococcus granulosus geminin 0.047 0.1915 0.191
Schistosoma mansoni phosphoglycerate mutase 0.004 0.0105 0.0098
Schistosoma mansoni chromobox protein 0.0046 0.0128 0.0121
Schistosoma mansoni hypothetical protein 0.0096 0.0338 0.0331
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0031 0.0065 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0026 0.0084
Giardia lamblia Histone acetyltransferase GCN5 0.0148 0.0559 0.091
Loa Loa (eye worm) hypothetical protein 0.0207 0.0806 0.08
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0026 0.0084
Plasmodium falciparum importin beta, putative 0.0042 0.0112 0.1994
Brugia malayi Pre-SET motif family protein 0.0283 0.1127 0.4993
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0037 0.0037
Mycobacterium tuberculosis Probable lipase LipE 0.0054 0.0164 0.1174
Echinococcus multilocularis lysine specific demethylase 5A 0.0026 0.0047 0.004
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0549 0.225 0.2244
Leishmania major DNA polymerase eta, putative 0.0046 0.0128 0.0128
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0068
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.004 0.0105 0.0099
Brugia malayi Cytochrome P450 family protein 0.0032 0.007 0.0282
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0121 0.0114
Mycobacterium ulcerans phosphoglycerate mutase 0.004 0.0105 0.0179
Plasmodium falciparum phd finger protein, putative 0.0022 0.0027 0.0489
Onchocerca volvulus 0.004 0.0105 0.0085
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0032 0.007 0.0033
Brugia malayi latrophilin 2 splice variant baaae 0.0207 0.0806 0.3561
Leishmania major hypothetical protein, conserved 0.004 0.0105 0.0105
Onchocerca volvulus 0.0082 0.0282 0.0263
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0107 0.0386 0.035
Brugia malayi MH1 domain containing protein 0.0018 0.0012 0.0021
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.01 0.0355 0.0348
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0091 0.0319 0.0312
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0026 0.0019
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0032 0.0069 0.0069
Echinococcus multilocularis lipoxygenase domain containing protein 0.007 0.0231 0.0224
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2388 0.9993 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0026 0.0019
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0148 0.0111
Loa Loa (eye worm) hypothetical protein 0.0042 0.0111 0.0104
Trichomonas vaginalis penicillin-binding protein, putative 0.0054 0.0164 0.1267
Leishmania major hypothetical protein, conserved 0.004 0.0105 0.0105
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Echinococcus multilocularis musashi 0.0082 0.0282 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0026 0.0019
Mycobacterium leprae Probable lipase LipE 0.0054 0.0164 1
Schistosoma mansoni hypothetical protein 0.047 0.1915 0.191
Toxoplasma gondii histone lysine methyltransferase SET1 0.0133 0.0495 0.8029
Onchocerca volvulus 0.0054 0.0164 0.0144
Leishmania major importin beta-1 subunit, putative 0.0034 0.0078 0.0078
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0054 0.0164 0.1174
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0073 0.0066
Onchocerca volvulus Alhambra homolog 0.0022 0.0027 0.0007
Loa Loa (eye worm) hypothetical protein 0.0082 0.0282 0.0276
Brugia malayi phosphoglycerate mutase family protein 0.004 0.0105 0.0438
Brugia malayi cytochrome P450 0.0032 0.007 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0026 0.0019
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0046 0.0046
Schistosoma mansoni rab6-interacting 0.007 0.0231 0.0224
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0031 0.0065 0.0064
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0026 0.0019
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0042 0.0111 0.0105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0096 0.0338 0.0332
Echinococcus multilocularis lamin 0.0082 0.0282 0.0276
Trypanosoma brucei unspecified product 0.0019 0.0017 0.0017
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0091 0.0319 0.0282
Toxoplasma gondii phosphoglycerate mutase family protein 0.004 0.0105 0.1707
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0098
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0031 0.0065 0.1055
Trichomonas vaginalis phosphoglycerate mutase, putative 0.004 0.0105 0.0813
Trichomonas vaginalis phosphoglycerate mutase, putative 0.004 0.0105 0.0813
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0032 0.007 0.0504
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0302 0.1208 0.5357
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0017
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0024 0.0037 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Echinococcus granulosus GPCR family 2 0.0096 0.0338 0.0332
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0032 0.007 0.012
Schistosoma mansoni ran 0.0031 0.0065 0.0058
Schistosoma mansoni hypothetical protein 0.047 0.1915 0.191
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0022 0.0027 0.002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0026 0.0084
Mycobacterium ulcerans lipoprotein LpqD 0.004 0.0105 0.0179
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2388 0.9993 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2388 0.9993 1
Echinococcus multilocularis lamin dm0 0.0082 0.0282 0.0276
Echinococcus multilocularis tumor protein p63 0.0326 0.1307 0.1301
Trichomonas vaginalis esterase, putative 0.0054 0.0164 0.1267
Schistosoma mansoni aldehyde dehydrogenase 0.0128 0.0474 0.0467
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0091 0.0319 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0039 0.0099 0.0061
Mycobacterium tuberculosis Probable hydrolase 0.0054 0.0164 0.1174
Schistosoma mansoni smad 0.0033 0.0073 0.0066
Brugia malayi ImpB/MucB/SamB family protein 0.0065 0.0209 0.09
Echinococcus multilocularis inositol monophosphatase 1 0.0024 0.0037 0.0031
Brugia malayi hypothetical protein 0.031 0.1239 0.5495
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0026 0.0019
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0096 0.0338 0.0332
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0054 0.0164 0.0157
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.004 0.0105 0.0099
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0046 0.0039
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Treponema pallidum phosphoglyceromutase 0.004 0.0105 1
Schistosoma mansoni hypothetical protein 0.0886 0.3666 0.3661
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0164 1
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1019 0.4227 0.4208
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0026 0.0084
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0283 0.1127 0.1121
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0024 0.0038 0.0032
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0073 0.0067
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0026 0.0084
Schistosoma mansoni smad1 5 8 and 0.0033 0.0073 0.0066
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0036 0.0088 0.0359
Loa Loa (eye worm) hypothetical protein 0.0065 0.0209 0.0202
Brugia malayi phosphoglycerate mutase family protein 0.004 0.0105 0.0438
Giardia lamblia Hypothetical protein 0.1409 0.5871 1
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0026 0.0084
Trypanosoma brucei DNA polymerase eta, putative 0.0065 0.0209 0.0209
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0024 0.0037 0.0288
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0026 0.0084
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0039 0.0099 0.0093
Trichomonas vaginalis chromobox protein, putative 0.0046 0.0128 0.099
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0162 0.0616 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Schistosoma mansoni cpg binding protein 0.0066 0.0212 0.0205
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0032 0.007 0.0504
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2347 0.9823 0.9829
Mycobacterium ulcerans hypothetical protein 0.004 0.0105 0.0179
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0098
Brugia malayi MH1 domain containing protein 0.0018 0.0012 0.0021
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0197 0.0191
Giardia lamblia DINP protein human, muc B family 0.0028 0.0053 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0027 0.002
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.004 0.0105 1
Onchocerca volvulus Protein UBASH3A homolog 0.004 0.0105 0.0085
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0068
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0028 0.0053 0.0047
Leishmania major GTP-binding protein, putative 0.0031 0.0065 0.0065
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0073 0.0066
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0162 0.0616 1
Plasmodium vivax importin-beta 2, putative 0.0042 0.0112 0.181
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0078 0.0604
Schistosoma mansoni cytochrome P450 0.0032 0.007 0.0063
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0128 0.0474 0.0474
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0062 0.0055
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0065 0.0028
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0026 0.0019
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0107 0.0386 0.0387
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0026 0.0019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0028 0.0053 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0032 0.007 0.0504
Brugia malayi hypothetical protein 0.007 0.0231 0.0998
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0043 0.0334
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1409 0.5871 1
Echinococcus granulosus transcription factor btf3 0.0026 0.0046 0.0039
Loa Loa (eye worm) cytochrome P450 family protein 0.005 0.0148 0.0141
Mycobacterium ulcerans DNA polymerase IV 0.0028 0.0053 0.0091
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0302 0.1208 0.1203
Loa Loa (eye worm) transcription factor SMAD2 0.0481 0.1961 0.1957
Mycobacterium ulcerans hypothetical protein 0.004 0.0105 0.0179
Brugia malayi ImpB/MucB/SamB family protein 0.0028 0.0053 0.0206
Loa Loa (eye worm) hypothetical protein 0.2388 0.9993 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0281 0.1121 0.1115
Trichomonas vaginalis inositol monophosphatase, putative 0.0024 0.0037 0.0288
Echinococcus granulosus PHD finger protein rhinoceros 0.0022 0.0027 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0028 0.0053 0.0382
Onchocerca volvulus 0.0322 0.1291 0.1274
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Onchocerca volvulus 0.007 0.0231 0.0211
Echinococcus multilocularis muscleblind protein 0.0315 0.1261 0.1255
Echinococcus granulosus phosphoglycerate mutase 0.004 0.0105 0.0099
Schistosoma mansoni survival motor neuron protein 0.0036 0.0088 0.0081
Onchocerca volvulus 0.0054 0.0164 0.0144
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.0111 0.0104
Schistosoma mansoni smad1 5 8 and 0.0033 0.0073 0.0066
Trypanosoma brucei unspecified product 0.0028 0.0053 0.0053
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0073 0.0066
Echinococcus granulosus cpg binding protein 0.0066 0.0212 0.0206
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0024 0.0038 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0024 0.0038 0.0031
Brugia malayi nuclear receptor NHR-88 0.0021 0.0026 0.0084
Onchocerca volvulus Huntingtin homolog 0.0178 0.0686 0.0668
Loa Loa (eye worm) CYP4Cod1 0.005 0.0148 0.0141
Brugia malayi hypothetical protein 0.0024 0.0038 0.0139
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0073 0.0067
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.0112 0.0112
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.004 0.0105 0.0179
Echinococcus granulosus beta LACTamase domain containing family member 0.0054 0.0164 0.0157
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0026 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.2388 0.9993 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0043 0.0334
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0053 0.0053
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0105 0.0754
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0026 0.0019
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Echinococcus multilocularis cpg binding protein 0.0066 0.0212 0.0206
Echinococcus granulosus lipoxygenase domain containing protein 0.007 0.0231 0.0224
Brugia malayi Cytochrome P450 family protein 0.0112 0.0408 0.1786
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0032 0.007 0.012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Echinococcus multilocularis lipoxygenase domain containing protein 0.007 0.0231 0.0224
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0282 0.1228
Echinococcus granulosus dna polymerase eta 0.0065 0.0209 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0043 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0026 0.0084
Trichomonas vaginalis importin beta-1, putative 0.0034 0.0078 0.0604
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0032 0.0069 0.0032
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0026 0.0019
Loa Loa (eye worm) nuclear factor I 0.0018 0.0012 0.0005
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.004 0.0105 0.0068
Echinococcus granulosus neuropeptide receptor A26 0.0654 0.2692 0.2687
Echinococcus multilocularis geminin 0.047 0.1915 0.191
Echinococcus granulosus dna polymerase kappa 0.0028 0.0053 0.0047
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.004 0.0105 0.0068
Loa Loa (eye worm) hypothetical protein 0.0178 0.0686 0.068
Brugia malayi MH2 domain containing protein 0.0033 0.0073 0.0296
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.004 0.0105 0.0179
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0164 0.1267
Schistosoma mansoni intermediate filament proteins 0.0082 0.0282 0.0276
Schistosoma mansoni hypothetical protein 0.0207 0.0806 0.0799
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1019 0.4227 0.423
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0026 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0032 0.007 0.0504
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0026 0.0084
Echinococcus multilocularis transcription factor Dp 1 0.0053 0.0157 0.0151
Trypanosoma cruzi glycerolphosphate mutase, putative 0.004 0.0105 0.0068
Echinococcus multilocularis muscleblind protein 1 0.0315 0.1261 0.1255
Brugia malayi Smad1 0.0033 0.0073 0.0296
Echinococcus granulosus tumor protein p63 0.0326 0.1307 0.1301
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0046 0.0352
Loa Loa (eye worm) hypothetical protein 0.0022 0.0027 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0017
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0068
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Giardia lamblia Hypothetical protein 0.1409 0.5871 1
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.004 0.0105 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Schistosoma mansoni Smad4 0.0033 0.0073 0.0066
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0128 0.0474 0.0467
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0026 0.0201
Trypanosoma brucei RNA helicase, putative 0.0081 0.0275 0.0275
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0046 0.0078
Onchocerca volvulus 0.2388 0.9993 1
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0026 0.0019
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0073 0.0067
Schistosoma mansoni ran 0.0031 0.0065 0.0058
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Leishmania major cytochrome p450-like protein 0.0032 0.007 0.007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0026 0.0084
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0032 0.007 0.012
Loa Loa (eye worm) cytochrome P450 0.0032 0.007 0.0063
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.004 0.0105 0.0754
Echinococcus granulosus histone acetyltransferase KAT2B 0.0534 0.2185 0.218
Loa Loa (eye worm) hypothetical protein 0.0038 0.0096 0.009
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0026 0.0019
Toxoplasma gondii hypothetical protein 0.0036 0.0089 0.1445
Schistosoma mansoni hypothetical protein 0.0036 0.0088 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Leishmania major phosphoglycerate mutase protein, putative 0.004 0.0105 0.0105
Loa Loa (eye worm) Smad1 0.0033 0.0073 0.0066
Trypanosoma brucei importin beta-1 subunit, putative 0.0042 0.0112 0.0112
Onchocerca volvulus Huntingtin homolog 0.0178 0.0686 0.0668
Loa Loa (eye worm) hypothetical protein 0.2347 0.9823 0.983
Loa Loa (eye worm) hypothetical protein 0.1369 0.5701 0.5702
Entamoeba histolytica Ran family GTPase 0.0031 0.0065 0.0111
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0032 0.007 0.0504
Echinococcus multilocularis PHD finger protein rhinoceros 0.0022 0.0027 0.0021
Brugia malayi Cytochrome P450 family protein 0.005 0.0148 0.0627
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0028 0.0053 0.0053
Echinococcus granulosus 6 phosphofructo 2 kinase:fructose 2 0.2388 0.9993 0.9993
Echinococcus granulosus peregrin 0.0035 0.0084 0.0077
Echinococcus multilocularis neuropeptide receptor A26 0.0654 0.2692 0.2687
Echinococcus granulosus phosphoglycerate mutase 0.004 0.0105 0.0099
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0091 0.0319 0.0312
Toxoplasma gondii PHD-finger domain-containing protein 0.0022 0.0027 0.0444
Toxoplasma gondii cytochrome p450 superfamily protein 0.0032 0.007 0.114
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0042 0.0111 0.1804
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0062 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0049 0.0143 0.0136
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0032 0.007 0.012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0028 0.0053 0.0047
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0282 0.0276
Schistosoma mansoni hypothetical protein 0.0022 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.004 0.0103 0.0096
Echinococcus granulosus phosphoglycerate mutase 0.004 0.0105 0.0099
Leishmania major phosphoglycerate mutase family member 5, putative 0.004 0.0105 0.0105
Echinococcus granulosus jumonji domain containing protein 0.003 0.0063 0.0057
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0281 0.1121 0.1115
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0032 0.007 0.012
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0031 0.0065 0.0058
Onchocerca volvulus 0.004 0.0105 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0046 0.0352
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0054 0.0164 0.0157
Schistosoma mansoni 6-phosphofructokinase 0.2388 0.9993 0.9993
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0034 0.0078 0.0604
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0032 0.007 0.0504
Trypanosoma brucei phosphoglycerate mutase, putative 0.004 0.0105 0.0105
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0032 0.007 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0026 0.0084
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0096 0.0338 0.0332
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0103 0.0096
Loa Loa (eye worm) hypothetical protein 0.0042 0.0112 0.0105
Entamoeba histolytica hypothetical protein 0.0034 0.0078 0.0133
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0026 0.0019
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Schistosoma mansoni loxhd1 0.007 0.0231 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.01 0.0355 0.155
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.2347 0.9823 0.9829
Mycobacterium ulcerans aldehyde dehydrogenase 0.0128 0.0474 0.0807
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0282 0.0276
Loa Loa (eye worm) hypothetical protein 0.0054 0.0164 0.0157
Loa Loa (eye worm) MH2 domain-containing protein 0.0481 0.1961 0.1957
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0226 0.0888 0.0855
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.2347 0.9823 0.983
Brugia malayi PHD-finger family protein 0.0022 0.0027 0.0091
Echinococcus granulosus histone lysine methyltransferase setb 0.0042 0.0111 0.0105
Mycobacterium ulcerans hypothetical protein 0.0054 0.0164 0.0279
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0005
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0551 0.2255 0.225
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.004 0.0105 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0026 0.0084
Schistosoma mansoni hypothetical protein 0.0096 0.0338 0.0331
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0032 0.007 0.012
Brugia malayi beta-lactamase family protein 0.0054 0.0164 0.0699
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0026 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0032 0.007 0.0504
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0105
Echinococcus granulosus chromobox protein 1 0.0046 0.0128 0.0121
Trichomonas vaginalis set domain proteins, putative 0.0322 0.1291 1
Onchocerca volvulus Protein UBASH3A homolog 0.004 0.0105 0.0085
Echinococcus multilocularis snurportin 1 0.0446 0.1816 0.1811
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0026 0.0019
Loa Loa (eye worm) latrophilin receptor protein 2 0.0096 0.0338 0.0332
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0046 0.0816
Echinococcus granulosus importin subunit beta 1 0.0042 0.0112 0.0105
Schistosoma mansoni hypothetical protein 0.004 0.0105 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0028 0.0052 0.0397
Loa Loa (eye worm) heterochromatin protein 1 0.0046 0.0128 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0046 0.0352
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0032 0.007 0.012
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.004 0.0105 0.0068
Leishmania major hypothetical protein, conserved 0.0054 0.0164 0.0164
Plasmodium vivax phosphoglucomutase-2, putative 0.004 0.0105 0.1707
Trichomonas vaginalis chromobox protein, putative 0.0028 0.0052 0.0397
Echinococcus granulosus neuropeptide s receptor 0.0654 0.2692 0.2687
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0032 0.007 0.012
Schistosoma mansoni lamin 0.0082 0.0282 0.0276
Loa Loa (eye worm) hypothetical protein 0.0178 0.0686 0.068
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0164 0.2657
Echinococcus granulosus muscleblind protein 0.0315 0.1261 0.1255
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.004 0.0105 0.0099
Echinococcus granulosus RUN 0.007 0.0231 0.0224
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0026 0.0019
Entamoeba histolytica acetyltransferase, GNAT family 0.0148 0.0559 0.0953
Echinococcus multilocularis RUN 0.007 0.0231 0.0224
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0026 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0032 0.007 0.0504
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0026 0.0019
Schistosoma mansoni hypothetical protein 0.0446 0.1816 0.181
Plasmodium falciparum phosphoglycerate mutase, putative 0.004 0.0105 0.188
Brugia malayi jmjC domain containing protein 0.0072 0.0237 0.1024
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0065
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0054 0.0164 0.0279
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0026 0.0019
Trichomonas vaginalis ran, putative 0.0031 0.0065 0.0502
Brugia malayi Doublecortin family protein 0.007 0.0231 0.0998
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0226 0.0888 0.0855
Echinococcus multilocularis phosphoglycerate mutase 0.004 0.0105 0.0099
Loa Loa (eye worm) hypothetical protein 0.007 0.0231 0.0224
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0175 0.0168
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0053 0.0016
Schistosoma mansoni terminal deoxycytidyl transferase 0.0028 0.0053 0.0046
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0032 0.007 0.012
Plasmodium falciparum LCCL domain-containing protein 0.007 0.0231 0.4128
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0026 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0042 0.0111 0.0104
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.004 0.0105 0.0179
Plasmodium vivax SET domain containing protein 0.0016 0.0004 0.0065
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0091 0.0319 0.0319
Loa Loa (eye worm) hypothetical protein 0.0048 0.0136 0.0129
Echinococcus multilocularis jumonji domain containing protein 0.003 0.0063 0.0057
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1019 0.4227 0.4208
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0026 0.0019
Mycobacterium ulcerans DNA polymerase IV 0.0028 0.0053 0.0091
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.004 0.0105 0.0179
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.004 0.0105 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.01 0.0355 0.0348
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.01 0.0355 0.0348
Mycobacterium ulcerans hypothetical protein 0.0119 0.0437 0.0745
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.0813
Loa Loa (eye worm) hypothetical protein 0.0315 0.1261 0.1256
Leishmania major basic transcription factor 3a, putative 0.0026 0.0046 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.0813
Brugia malayi beta-lactamase family protein 0.0054 0.0164 0.0699
Brugia malayi UBASH3A protein homolog 0.004 0.0105 0.0438
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0091 0.0319 0.1389
Trypanosoma cruzi DNA polymerase eta, putative 0.0065 0.0209 0.0172
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0026 0.0084
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0032 0.007 0.0504
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0105
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0065
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.01 0.0355 0.0348
Brugia malayi Importin beta-1 subunit 0.0042 0.0112 0.0466
Schistosoma mansoni lamin 0.0082 0.0282 0.0276
Trypanosoma cruzi DNA polymerase kappa, putative 0.0028 0.0053 0.0016
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0072 0.0237 0.023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0026 0.0019
Echinococcus granulosus phosphoglycerate mutase 0.004 0.0105 0.0099
Mycobacterium leprae putative cytochrome p450 0.0032 0.007 0.4292
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.004 0.0105 0.0105
Onchocerca volvulus 0.0049 0.0143 0.0123
Mycobacterium leprae conserved hypothetical protein 0.004 0.0105 0.6423
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0446 0.1816 0.1812
Schistosoma mansoni cpg binding protein 0.0062 0.0197 0.019
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0032 0.007 0.012
Trichomonas vaginalis penicillin-binding protein, putative 0.0054 0.0164 0.1267
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0028 0.0053 0.0046
Brugia malayi intermediate filament protein 0.0082 0.0282 0.1228
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.004 0.0105 0.0068
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0054 0.0164 0.0157
Plasmodium falciparum phosphoglucomutase-2 0.004 0.0105 0.188
Onchocerca volvulus 0.0036 0.0088 0.0068
Echinococcus granulosus lysine specific demethylase 5A 0.003 0.0062 0.0055
Echinococcus multilocularis microtubule associated protein 2 0.2389 1 1
Trypanosoma brucei unspecified product 0.0019 0.0017 0.0017
Brugia malayi hypothetical protein 0.007 0.0231 0.0998
Trypanosoma cruzi phosphoglycerate mutase, putative 0.004 0.0105 0.0068
Onchocerca volvulus 0.004 0.0105 0.0085
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0054 0.0164 0.0699
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0026 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0032 0.007 0.0504
Echinococcus multilocularis 0.0032 0.007 0.0064
Schistosoma mansoni phosphoglycerate mutase 0.004 0.0105 0.0098
Echinococcus multilocularis Protein lozenge 0.0039 0.0099 0.0092
Plasmodium vivax SET domain protein, putative 0.0042 0.0111 0.1804
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.004 0.0105 0.0754
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0032 0.007 0.012
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0046 0.0008
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0065
Brugia malayi Latrophilin receptor protein 2 0.0096 0.0338 0.1477
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0032 0.007 0.012
Trypanosoma cruzi cytochrome P450, putative 0.005 0.0148 0.0111
Brugia malayi steroid hormone receptor 0.0021 0.0026 0.0084
Mycobacterium tuberculosis Conserved hypothetical protein 0.0119 0.0437 0.3136
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0053 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0026 0.0084
Trypanosoma brucei DNA polymerase IV, putative 0.0028 0.0053 0.0053
Entamoeba histolytica deoxycytidyl transferase, putative 0.0028 0.0053 0.0091
Loa Loa (eye worm) hypothetical protein 0.0055 0.0165 0.0158
Schistosoma mansoni chromobox protein 0.0046 0.0128 0.0121
Brugia malayi beta-lactamase 0.0054 0.0164 0.0699
Echinococcus multilocularis Smad4 0.0033 0.0073 0.0067
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0032 0.007 0.0504
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0032 0.007 0.012
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0026 0.0006
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0032 0.007 0.012
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0549 0.225 0.2245
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0023 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0017 0.0017
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0024 0.0037 0.0608
Echinococcus granulosus phosphoglycerate mutase 0.004 0.0105 0.0099
Schistosoma mansoni hypothetical protein 0.0024 0.0038 0.0031
Brugia malayi CXXC zinc finger family protein 0.0062 0.0197 0.0848
Trypanosoma cruzi importin beta-1 subunit, putative 0.0034 0.0078 0.0041
Mycobacterium tuberculosis Conserved protein 0.004 0.0105 0.0754
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0072 0.0237 0.023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0026 0.0019
Mycobacterium ulcerans phosphoglycerate mutase 0.004 0.0105 0.0179
Onchocerca volvulus 0.0048 0.0136 0.0116
Loa Loa (eye worm) runx1 0.0039 0.0099 0.0092
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0032 0.007 0.0504
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0026 0.0019
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0121 0.051
Echinococcus granulosus intermediate filament protein 0.0082 0.0282 0.0276
Schistosoma mansoni rab6-interacting 0.007 0.0231 0.0224
Echinococcus multilocularis smad 0.0033 0.0073 0.0067
Brugia malayi chromobox protein homolog 3 0.0026 0.0043 0.0162
Echinococcus multilocularis Polycystic kidney disease protein 0.007 0.0231 0.0224
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0133 0.0497 0.0491
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0054 0.0164 0.1174
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0023 0.0016
Plasmodium vivax multidomain scavenger receptor, putative 0.007 0.0231 0.3748
Loa Loa (eye worm) acetyltransferase 0.0549 0.225 0.2246
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.004 0.0105 0.6423
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0026 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0103 0.0096
Onchocerca volvulus 0.0054 0.0164 0.0144
Loa Loa (eye worm) hypothetical protein 0.0037 0.0093 0.0086
Leishmania major glycerolphosphate mutase, putative 0.004 0.0105 0.0105
Trichomonas vaginalis phosphoglycerate mutase, putative 0.004 0.0105 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0053 0.0053
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0032 0.007 0.0504
Brugia malayi Calcitonin receptor-like protein seb-1 0.0302 0.1208 0.5357
Loa Loa (eye worm) hypothetical protein 0.0038 0.0096 0.009
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.004 0.0105 0.6423
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0032 0.007 0.0504
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0052 0.0199
Schistosoma mansoni jumonji/arid domain-containing protein 0.003 0.0062 0.0055

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 37.3 nM Displacement of [3H]N-alpha-methylhistamine from rhesus monkey histamine H3 receptor expressed in CHO cells ChEMBL. 24076172

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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