Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glutamate receptor, ionotropic, kainate 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | hypothetical protein | 0.0363 | 1 | 0.5 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0049 | 0.0709 | 0.4912 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0363 | 1 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0363 | 1 | 1 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0363 | 1 | 1 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.003 | 0.017 | 0.1333 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0036 | 0.034 | 0.2354 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0363 | 1 | 1 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.003 | 0.017 | 0.1176 |
Schistosoma mansoni | glutamate receptor kainate | 0.003 | 0.017 | 0.1333 |
Brugia malayi | Glutamate receptor 2 precursor | 0.003 | 0.017 | 1 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0068 | 0.1274 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.003 | 0.017 | 0.1333 |
Leishmania major | oxidoreductase-like protein | 0.0025 | 0 | 0.5 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0025 | 0.0008 | 0.0057 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0049 | 0.0709 | 0.4912 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0049 | 0.0709 | 0.4912 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0363 | 1 | 1 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0049 | 0.0709 | 0.4912 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0025 | 0 | 0.5 |
Onchocerca volvulus | 0.0025 | 0 | 0.5 | |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.003 | 0.017 | 0.1176 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0036 | 0.034 | 0.2354 |
Trypanosoma brucei | pteridine reductase 1 | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0025 | 0.0008 | 0.0057 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Brugia malayi | Glutamate receptor 1 precursor | 0.003 | 0.017 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.003 | 0.017 | 0.1176 |
Echinococcus granulosus | glutamate receptor 2 | 0.0036 | 0.034 | 0.2354 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0025 | 0 | 0.5 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor kainate | 0.0068 | 0.1274 | 1 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0363 | 1 | 1 |
Schistosoma mansoni | glutamate receptor AMPA | 0.003 | 0.017 | 0.1333 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.003 | 0.017 | 1 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0025 | 0 | 0.5 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor AMPA | 0.003 | 0.017 | 0.1333 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0036 | 0.034 | 0.2354 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0363 | 1 | 1 |
Leishmania major | pteridine reductase 1 | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | NMDA receptor | 0.0049 | 0.0709 | 0.4912 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.003 | 0.017 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0073 | 0.1444 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0036 | 0.034 | 0.2668 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.