Detailed information for compound 179398

Basic information

Technical information
  • TDR Targets ID: 179398
  • Name: 1-[3,5-bis(trifluoromethyl)phenyl]-3-cyano-2- (3-methylbutan-2-yl)guanidine
  • MW: 366.305 | Formula: C15H16F6N4
  • H donors: 2 H acceptors: 1 LogP: 5.14 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(C(C)C)/N=C(/Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)\NC#N
  • InChi: 1S/C15H16F6N4/c1-8(2)9(3)24-13(23-7-22)25-12-5-10(14(16,17)18)4-11(6-12)15(19,20)21/h4-6,8-9H,1-3H3,(H2,23,24,25)
  • InChiKey: SGADZQCQURIXJB-UHFFFAOYSA-N  

Network

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Synonyms

  • 1-[3,5-bis(trifluoromethyl)phenyl]-3-cyano-2-(1,2-dimethylpropyl)guanidine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0009 0.0062
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Echinococcus multilocularis NMDA receptor 0.0029 0.0036 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0052 0.0052
Schistosoma mansoni rab6-interacting 0.0022 0.0014 0.0014
Schistosoma mansoni tyrosine kinase 0.0028 0.0033 0.0033
Echinococcus granulosus suppressor of cytokine signaling 7 0.0022 0.0016 0.0016
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.0016 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0009 0.0062
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0036 0.0053 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0137 0.8441
Echinococcus granulosus suppressor of cytokine signaling 6 0.0022 0.0016 0.0016
Entamoeba histolytica SH2 domain containing protein 0.0022 0.0016 0.0037
Mycobacterium ulcerans lipase LipD 0.0037 0.0058 0.3439
Brugia malayi Protein kinase domain containing protein 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0033
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0022 0.0016 0.0016
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0009 0.0062
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0022 0.0016 0.0016
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0108 0.0108
Brugia malayi hypothetical protein 0.0022 0.0014 0.0014
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0036 0.0053 0.0053
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0621 0.166 0.166
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0108 0.0668
Echinococcus granulosus N chimaerin 0.0022 0.0016 0.0016
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.004 0.004
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase Lyn 0.0036 0.0054 0.0054
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0036 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis receptor type guanylyl cyclase 0.0028 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0022 0.0016 0.0002
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0108 0.0602
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0621 0.166 0.166
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0058 0.0814
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0058 0.0296
Echinococcus multilocularis tensin 0.0022 0.0016 0.0016
Echinococcus granulosus signal transduction protein lnk realted 0.0022 0.0016 0.0016
Leishmania major hypothetical protein, conserved 0.0037 0.0058 0.0569
Mycobacterium leprae Probable lipase LipE 0.0037 0.0058 0.5
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0016 0.0016
Echinococcus granulosus SH2 domain containing protein 7 0.0022 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.0569
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0053 0.0053
Schistosoma mansoni GTPase activating protein 0.0022 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase shark 0.0036 0.0053 0.0053
Echinococcus granulosus tyrosine protein kinase Src42A 0.0022 0.0016 0.0016
Brugia malayi Tyrosine-protein kinase abl-1 0.0036 0.0053 0.0053
Echinococcus multilocularis glutamate receptor 2 0.0045 0.0077 0.0077
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0036 0.0053 0.0053
Onchocerca volvulus 0.366 1 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0033 0.0033
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0022 0.0016 0.0002
Schistosoma mansoni tensin 0.0022 0.0016 0.0016
Brugia malayi STAT protein, DNA binding domain containing protein 0.0022 0.0016 0.0016
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0058 0.0058
Brugia malayi Sex muscle abnormal protein 5 0.0022 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0022 0.0014 0.0014
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0621 0.166 0.166
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0137 0.0137
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0129 0.0309 0.0309
Schistosoma mansoni tsg101-related 0.096 0.2591 0.2591
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.004 0.004
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0621 0.166 0.166
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0009 0.0374
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Schistosoma mansoni signal transduction protein lnk-related 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Echinococcus granulosus hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0022 0.0016 0.0016
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0137 0.0137
Schistosoma mansoni glutamate receptor NMDA 0.0045 0.0077 0.0077
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0097 0.0097
Onchocerca volvulus 0.0037 0.0058 0.0043
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Onchocerca volvulus 0.0621 0.166 0.1648
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0108 0.1093
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0621 0.166 0.166
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0058
Schistosoma mansoni SH2A 0.0022 0.0016 0.0016
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.004 0.004
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) TK protein kinase 0.0036 0.0053 0.0053
Mycobacterium ulcerans hypothetical protein 0.0037 0.0058 0.3439
Echinococcus granulosus sodium and chloride dependent glycine 0.0621 0.166 0.166
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase ABL1 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.366 1 1
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0055 0.0055
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0058 0.0814
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0009 0.0062
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0137 0.2143
Brugia malayi hypothetical protein 0.0022 0.0016 0.0016
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0036 0.0053 0.0053
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0058 0.3439
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.366 1 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0621 0.166 0.166
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Loa Loa (eye worm) serotonin transporter b 0.366 1 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Schistosoma mansoni tensin-related 0.0022 0.0016 0.0016
Echinococcus granulosus glutamate receptor 2 0.0045 0.0077 0.0077
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0108 0.0108
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0045 0.0077 0.0077
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0036 0.0053 0.0053
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0022 0.0016 0.0016
Brugia malayi MAP kinase sur-1 0.0056 0.0108 0.0108
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0108 0.1093
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0022 0.0016 0.0016
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0108 0.0108
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0097 0.0097
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0108 0.1093
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0009 0.0009
Echinococcus granulosus c src tyrosine kinase 0.0036 0.0053 0.0053
Echinococcus granulosus receptor type guanylyl cyclase 0.0028 0.0033 0.0033
Toxoplasma gondii hypothetical protein 0.0621 0.166 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Echinococcus multilocularis SHC transforming protein 3 0.0022 0.0016 0.0016
Brugia malayi Cytochrome P450 family protein 0.0017 0.0003 0.0003
Echinococcus multilocularis nmda type glutamate receptor 0.0105 0.0243 0.0243
Onchocerca volvulus 0.0621 0.166 0.1648
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0022 0.0016 0.0016
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0028 0.0033 0.0019
Echinococcus multilocularis SH2 motif 0.0022 0.0016 0.0016
Loa Loa (eye worm) SRC-1 0.0036 0.0053 0.0053
Mycobacterium ulcerans beta-lactamase 0.0037 0.0058 0.3439
Loa Loa (eye worm) hypothetical protein 0.0148 0.0361 0.0361
Brugia malayi Glutamate receptor 1 precursor 0.0029 0.0036 0.0036
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Loa Loa (eye worm) hypothetical protein 0.366 1 1
Echinococcus multilocularis serotonin receptor 0.0148 0.0361 0.0361
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0137 0.078
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0009 0.0009
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0137 0.0137
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0036 0.0053 0.0053
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Brugia malayi protein-tyrosine kinase 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Echinococcus multilocularis c src tyrosine kinase 0.0036 0.0053 0.0053
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0485 0.4995
Loa Loa (eye worm) solute carrier family 6 member 4 0.366 1 1
Echinococcus granulosus nmda type glutamate receptor 0.0105 0.0243 0.0243
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0621 0.166 1
Plasmodium falciparum amino acid transporter, putative 0.0621 0.166 1
Loa Loa (eye worm) glutamate receptor 2 0.0029 0.0036 0.0036
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0058 0.0814
Echinococcus multilocularis SH2 motif 0.0022 0.0016 0.0016
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0052 0.0097 0.0097
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0621 0.166 0.166
Brugia malayi hypothetical protein 0.0036 0.0053 0.0053
Schistosoma mansoni nck2/grb4 0.0022 0.0016 0.0016
Echinococcus granulosus SH2 motif 0.0022 0.0016 0.0016
Echinococcus multilocularis NCK adaptor protein 0.0022 0.0016 0.0016
Plasmodium vivax hypothetical protein, conserved 0.0621 0.166 1
Brugia malayi cytokine inducible SH2-containing protein 5 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0621 0.166 0.1648
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0108 0.1093
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0105 0.0243 0.0243
Schistosoma mansoni protein kinase 0.0028 0.0033 0.0033
Toxoplasma gondii ABC1 family protein 0.0037 0.0058 0.0296
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0621 0.166 0.166
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.1153 0.312 0.312
Echinococcus granulosus RUN 0.0022 0.0014 0.0014
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0036 0.0053 0.0211
Echinococcus granulosus SH2 motif 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0036 0.0053 0.0053
Trichomonas vaginalis set domain proteins, putative 0.0246 0.0629 0.4169
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0003 0.0003
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0621 0.166 0.166
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0108 1
Schistosoma mansoni ATP-binding cassette transporter 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni tensin 0.0022 0.0016 0.0016
Brugia malayi hypothetical protein 0.1153 0.312 0.312
Brugia malayi Doublecortin family protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0148 0.0361 0.0361
Plasmodium vivax amine transporter, putative 0.0621 0.166 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0137 0.8441
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0016 0.0016
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0621 0.166 0.166
Schistosoma mansoni ap endonuclease 0.0019 0.0009 0.0009
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0137 0.0137
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0014 0.0014
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0077 0.0077
Echinococcus granulosus tyrosine protein kinase Srms 0.0036 0.0053 0.0053
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0016 0.0016
Entamoeba histolytica hypothetical protein 0.0193 0.0485 0.2267
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Loa Loa (eye worm) beta-lactamase 0.0037 0.0058 0.0058
Brugia malayi Pre-SET motif family protein 0.0031 0.004 0.004
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0029 0.0036 0.0036
Schistosoma mansoni suppressor of cytokine signaling 0.0022 0.0016 0.0016
Brugia malayi Protein kinase domain containing protein 0.0036 0.0053 0.0053
Echinococcus granulosus glutamate NMDA receptor subunit 0.0029 0.0036 0.0036
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0075 0.0162 0.0154
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0329
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.0547 0.0547
Echinococcus multilocularis SH2 domain containing protein 7 0.0022 0.0016 0.0016
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0029 0.0036 0.0036
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0009 0.0009
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0058 0.0814
Entamoeba histolytica protein kinase, putative 0.0023 0.0018 0.0043
Brugia malayi tRNA modification GTPase TrmE family protein 0.0022 0.0016 0.0016
Echinococcus granulosus biogenic amine 5HT receptor 0.0148 0.0361 0.0361
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0029 0.0036 0.0036
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0784 0.2108 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni growth factor receptor-bound protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0033 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.004 0.004
Schistosoma mansoni sodium/chloride dependent transporter 0.0621 0.166 0.166
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0058 0.0569
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0058 0.0329
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0329
Loa Loa (eye worm) TK/ABL protein kinase 0.0036 0.0053 0.0053
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.004 0.004
Schistosoma mansoni vav2 0.0022 0.0016 0.0016
Brugia malayi Glutamate receptor 2 precursor 0.0029 0.0036 0.0036
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0369 0.0967 1
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0108 0.0108
Brugia malayi Protein kinase domain containing protein 0.0036 0.0053 0.0053
Brugia malayi beta-lactamase 0.0037 0.0058 0.0058
Brugia malayi Guanylyl cyclase protein 23 0.0028 0.0033 0.0033
Echinococcus multilocularis sodium and chloride dependent glycine 0.0621 0.166 0.166
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0036 0.0053 0.0053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0621 0.166 1
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0064 0.0064
Echinococcus granulosus tyrosine protein kinase Src64B 0.0036 0.0053 0.0053
Onchocerca volvulus 0.0036 0.0053 0.0039
Entamoeba histolytica hypothetical protein 0.0193 0.0485 0.2267
Echinococcus multilocularis tensin 0.0022 0.0016 0.0016
Schistosoma mansoni sodium/chloride dependent transporter 0.0622 0.1662 0.1662
Schistosoma mansoni lipoxygenase 0.0129 0.0309 0.0309
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0621 0.166 1
Trypanosoma cruzi hypothetical protein, conserved 0.0193 0.0485 0.4995
Onchocerca volvulus 0.0037 0.0058 0.0043
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Echinococcus multilocularis serotonin transporter 0.366 1 1
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0022 0.0016 0.0016
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0023 0.0018 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0077 0.0077
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0058 0.0058
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0036 0.0053 0.0053
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.0016 0.0016
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0016 0.0016
Echinococcus granulosus tyrosine kinase 0.0028 0.0033 0.0033
Brugia malayi Tensin 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0238 0.061 1
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0055 0.0055
Onchocerca volvulus 0.0022 0.0016 0.0002
Loa Loa (eye worm) hypothetical protein 0.0148 0.0361 0.0361
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0621 0.166 0.166
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0036 0.0036
Onchocerca volvulus 0.0022 0.0016 0.0002
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0058 0.0058
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0022 0.0016 0.0016
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0014 0.0014
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0058 0.5
Onchocerca volvulus 0.0036 0.0053 0.0039
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.004 0.019
Schistosoma mansoni glutamate receptor NMDA 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0014 0.0034
Leishmania major hypothetical protein, conserved 0.0369 0.0967 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0022 0.0016 0.0016
Schistosoma mansoni suppressor of cytokine signaling 0.0022 0.0016 0.0016
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0369 0.0967 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.0016 0.0016
Echinococcus multilocularis glutamate receptor 2 0.0029 0.0036 0.0036
Brugia malayi Cytochrome P450 family protein 0.0017 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0216 0.0547 0.0547
Brugia malayi RhoGAP domain containing protein 0.0022 0.0016 0.0016
Schistosoma mansoni tsg101-related 0.096 0.2591 0.2591
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Echinococcus multilocularis 0.0022 0.0016 0.0016
Echinococcus multilocularis N chimaerin 0.0022 0.0016 0.0016
Schistosoma mansoni ap endonuclease 0.0019 0.0009 0.0009
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0022 0.0016 0.0016
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0029 0.0036 0.0036
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.366 1 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0022 0.0016 0.0016
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0045 0.0077 0.0077
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0029 0.0036 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Echinococcus multilocularis sodium and chloride dependent glycine 0.0621 0.166 0.166
Schistosoma mansoni lipoxygenase 0.009 0.0203 0.0203
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0129 0.0309 0.0309
Onchocerca volvulus 0.0036 0.0053 0.0039
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0058 0.0058
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0036 0.0053 0.0053
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0048 0.0265
Echinococcus multilocularis serotonin receptor 0.0148 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0485 0.3198
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0075 0.0162 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0037 0.0037
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0621 0.166 0.166
Schistosoma mansoni tensin-related 0.0022 0.0016 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.004 0.004
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0022 0.0016 0.0002
Brugia malayi hypothetical protein 0.0621 0.166 0.166
Echinococcus granulosus tumor susceptibility gene 101 protein 0.1153 0.312 0.312
Echinococcus multilocularis tyrosine protein kinase Abl 0.0036 0.0053 0.0053
Loa Loa (eye worm) RGC/RGC protein kinase 0.0028 0.0033 0.0033
Schistosoma mansoni sodium/chloride dependent transporter 0.366 1 1
Schistosoma mansoni polycystin 1-related 0.0022 0.0014 0.0014
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0108 0.0668
Echinococcus multilocularis RUN 0.0022 0.0014 0.0014
Echinococcus granulosus NCK adaptor protein 0.0022 0.0016 0.0016
Schistosoma mansoni glutamate receptor AMPA 0.0029 0.0036 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0137 0.8441
Onchocerca volvulus 0.0037 0.0058 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0108 0.0668
Echinococcus multilocularis tyrosine protein kinase shark 0.0036 0.0053 0.0053
Brugia malayi SH2 domain containing protein 0.0036 0.0053 0.0053
Treponema pallidum sodium- and chloride- dependent transporter 0.366 1 1
Onchocerca volvulus 0.0031 0.004 0.0026
Echinococcus granulosus sodium and chloride dependent glycine 0.0621 0.166 0.166
Loa Loa (eye worm) hypothetical protein 0.0031 0.0041 0.0041
Echinococcus multilocularis tyrosine protein kinase Blk 0.0036 0.0053 0.0053
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0621 0.166 0.166
Brugia malayi SRC-1 0.0036 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0193 0.0485 0.2267
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0036 0.0036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0621 0.166 0.166
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0108 0.1093
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0036 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0064 0.0064
Echinococcus granulosus growth factor receptor bound protein 2 0.0022 0.0016 0.0016
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0621 0.166 0.166
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0485 0.3198
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0014 0.0034
Brugia malayi Protein kinase domain containing protein 0.0036 0.0053 0.0053
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0058 0.3439
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0058 0.0814
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0108 0.0108
Schistosoma mansoni sodium-dependent amino acid transporter 0.0621 0.166 0.166
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Entamoeba histolytica hypothetical protein 0.0193 0.0485 0.2267
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0035 0.0052 0.0052
Echinococcus multilocularis tyrosine protein kinase Srms 0.0036 0.0053 0.0053
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0014 0.0014
Plasmodium vivax SET domain protein, putative 0.0031 0.004 0.019
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0045 0.0077 0.0077
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0058
Brugia malayi Receptor family ligand binding region containing protein 0.0028 0.0033 0.0033
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0058 0.0569
Echinococcus granulosus tensin 0.0022 0.0016 0.0016
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0137 0.1397
Onchocerca volvulus 0.0036 0.0053 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) STAT protein 0.0022 0.0016 0.0016
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0036 0.0053 0.0053
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0029 0.0036 0.0036
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0022 0.0016 0.0016
Schistosoma mansoni rab6-interacting 0.0022 0.0014 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0108 0.0668
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0029 0.0036 0.0036
Onchocerca volvulus 0.0036 0.0053 0.0039
Plasmodium falciparum transporter, putative 0.0621 0.166 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0621 0.166 0.166
Loa Loa (eye worm) SH2 domain-containing protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0016 0.0016
Trypanosoma brucei protein kinase, putative 0.0056 0.0108 0.1093
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Brugia malayi SH2 domain containing protein 0.0036 0.0053 0.0053
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Echinococcus multilocularis SH2 motif 0.0022 0.0016 0.0016
Echinococcus granulosus serotonin transporter 0.366 1 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0108 0.1093
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0058
Schistosoma mansoni adapter molecule crk 0.0022 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0621 0.166 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.004 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0329
Schistosoma mansoni tyrosine kinase 0.0028 0.0033 0.0033
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0621 0.166 0.166
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0022 0.0014 0.0014
Loa Loa (eye worm) norepinephrine transporter 0.366 1 1
Echinococcus granulosus SH2 domain containing adapter protein F 0.0022 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0036 0.0053 0.0053
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0621 0.166 0.166
Echinococcus granulosus tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Schistosoma mansoni shc transforming protein 0.0022 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Echinococcus granulosus tyrosine kinase 0.0036 0.0053 0.0053
Echinococcus multilocularis growth factor receptor bound protein 2 0.0022 0.0016 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0022 0.0016 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0055 0.0055
Brugia malayi Variant SH3 domain containing protein 0.0022 0.0016 0.0016
Onchocerca volvulus 0.0246 0.0629 0.0616
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0009 0.0009
Trichomonas vaginalis hypothetical protein 0.0562 0.1497 1
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0075 0.0162 0.0154
Echinococcus granulosus SHC transforming protein 3 0.0022 0.0016 0.0016
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine kinase 0.0028 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0009 0.5
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0028 0.0033 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Schistosoma mansoni tensin 0.0022 0.0016 0.0016
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0621 0.166 0.166
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0058 0.0814
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0108 0.1093
Loa Loa (eye worm) hypothetical protein 0.1153 0.312 0.312
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0016 0.0016
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Schistosoma mansoni tyrosine kinase 0.0036 0.0053 0.0053
Schistosoma mansoni loxhd1 0.0022 0.0014 0.0014
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0058 0.0058
Echinococcus multilocularis tyrosine kinase 0.0036 0.0053 0.0053
Echinococcus granulosus tyrosine kinase 0.0036 0.0053 0.0053
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0036 0.0053 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0058 0.0329
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0022 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0037 0.0058 0.0814
Schistosoma mansoni glutamate receptor kainate 0.0029 0.0036 0.0036
Brugia malayi beta-lactamase family protein 0.0037 0.0058 0.0058
Schistosoma mansoni tsg101-related 0.0784 0.2108 0.2108
Onchocerca volvulus 0.0036 0.0053 0.0039
Echinococcus granulosus glutamate receptor subunit protein glur 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0621 0.166 0.166
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0621 0.166 0.166
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0058 0.0814
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0075 0.0162 0.2557
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0193 0.0485 0.4995
Loa Loa (eye worm) glutamate receptor 1 0.0029 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0048 0.0265
Onchocerca volvulus 0.0022 0.0016 0.0002
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0045 0.0077 0.0077
Onchocerca volvulus 0.0022 0.0016 0.0002
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.0016 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0108 0.0108
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0621 0.166 0.166
Loa Loa (eye worm) TK/FER protein kinase 0.0036 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0022 0.0016 0.0016
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0022 0.0016 0.0002
Echinococcus granulosus expressed conserved protein 0.0022 0.0016 0.0016
Trichomonas vaginalis esterase, putative 0.0037 0.0058 0.0329
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0097 0.0097
Toxoplasma gondii hypothetical protein 0.0621 0.166 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0036 0.0053 0.0053
Echinococcus multilocularis signal transduction protein lnk realted 0.0022 0.0016 0.0016
Brugia malayi SH2 domain containing protein 0.0022 0.0016 0.0016

Activities

Activity type Activity value Assay description Source Reference
Efficacy (functional) = 69 % In vitro efficacy to inhibit glucose stimulated insulin release in beta-TC6 cells from rat islets ChEMBL. 15163199
Efficacy (functional) = 69 % In vitro efficacy to inhibit glucose stimulated insulin release in beta-TC6 cells from rat islets ChEMBL. 15163199
IC50 (functional) = 5.2 uM In vitro ability to inhibit glucose stimulated insulin release in beta-TC6 cells from rat islets ChEMBL. 15163199
IC50 (functional) = 5.2 uM In vitro ability to inhibit glucose stimulated insulin release in beta-TC6 cells from rat islets ChEMBL. 15163199
IC50 (functional) = 5.5 uM Ability to repolarize betaTC3 cell membrane potential ChEMBL. 15163199
IC50 (functional) = 5.5 uM Ability to repolarize betaTC3 cell membrane potential ChEMBL. 15163199
IC50 (functional) = 17.6 uM Relaxation of phenylephrine precontracted rat isolated aorta rings. ChEMBL. 15163199

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Mus musculus ChEMBL23 15163199

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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