Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.011 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0205 | 0.0566 |
Echinococcus granulosus | geminin | 0.0197 | 0.267 | 0.2664 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0389 | 0.0879 |
Onchocerca volvulus | 0.0042 | 0.0389 | 0.0613 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0042 | 0.0389 | 0.1031 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.2013 | 0.5314 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Toxoplasma gondii | bicoid-interacting protein BIN3 | 0.0023 | 0.0109 | 0.029 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0042 | 0.0389 | 0.0382 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0389 | 0.1031 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0251 | 0.0244 |
Schistosoma mansoni | acetylcholinesterase | 0.0046 | 0.045 | 0.045 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0478 | 0.0471 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0046 | 0.045 | 0.2169 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0033 | 0.0069 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.1251 | 0.1251 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0033 | 0.0026 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0673 | 0.0666 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0046 | 0.045 | 0.0443 |
Onchocerca volvulus | 0.0046 | 0.045 | 0.0813 | |
Onchocerca volvulus | 0.0031 | 0.0225 | 0.0084 | |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0251 | 0.0251 |
Onchocerca volvulus | 0.0042 | 0.0389 | 0.0613 | |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0145 | 0.3734 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0098 | 0.122 | 0.122 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0696 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0225 | 0.0225 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0389 | 0.1031 |
Echinococcus multilocularis | neuroligin | 0.0046 | 0.045 | 0.0443 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0046 | 0.045 | 0.0443 |
Echinococcus granulosus | neuroligin | 0.0046 | 0.045 | 0.0443 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.045 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0033 | 0.0033 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0007 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0033 | 0.0033 |
Echinococcus multilocularis | histone arginine methyltransferase CARMER | 0.0254 | 0.3506 | 0.3502 |
Echinococcus granulosus | methyltransferase protein 5 | 0.0023 | 0.0109 | 0.0102 |
Brugia malayi | Carm1-pending protein | 0.0254 | 0.3506 | 0.9273 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0021 | 0.0089 | 0.0216 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0375 | 0.0367 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.045 | 0.1174 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0079 | 0.0079 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0042 | 0.0389 | 0.1031 |
Onchocerca volvulus | 0.0046 | 0.045 | 0.0813 | |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0306 | 0.0299 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0033 | 0.0026 |
Echinococcus granulosus | protein arginine N methyltransferase 7 | 0.0023 | 0.0109 | 0.0102 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0046 | 0.045 | 0.0443 |
Toxoplasma gondii | ABC1 family protein | 0.0042 | 0.0389 | 0.109 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0023 | 0.0109 | 0.2802 |
Schistosoma mansoni | phd/f-box containing protein | 0.0025 | 0.0145 | 0.0145 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0098 | 0.122 | 0.1214 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0036 | 0.0036 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0033 | 0.0026 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0025 | 0.0145 | 0.0138 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0026 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0389 | 1 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0029 | 0.0198 | 0.019 |
Onchocerca volvulus | 0.0152 | 0.2013 | 0.5862 | |
Brugia malayi | Carboxylesterase family protein | 0.0273 | 0.3781 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0042 | 0.0389 | 0.1031 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0682 | 0.0675 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0033 | 0.0033 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0335 | 0.0335 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0375 | 0.0367 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0042 | 0.0389 | 0.101 |
Trypanosoma brucei | RNA helicase, putative | 0.0101 | 0.1251 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0478 | 0.1246 |
Loa Loa (eye worm) | carboxylesterase | 0.0273 | 0.3781 | 1 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0025 | 0.0145 | 0.0138 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0025 | 0.0145 | 0.0138 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0109 | 0.0109 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.0059 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0025 | 0.0145 | 0.3734 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.045 | 0.1174 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.267 | 0.267 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0056 | 0.0595 | 0.1557 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.045 | 0.045 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0132 | 0.0124 |
Brugia malayi | jmjC domain containing protein | 0.0098 | 0.122 | 0.3215 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0673 | 0.0666 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0205 | 0.0198 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.1543 | 0.4068 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0132 | 0.0132 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0268 | 0.3705 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0673 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0273 | 0.3781 | 0.3776 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0033 | 0.0033 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0273 | 0.3781 | 0.3781 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0007 | 0.0059 |
Echinococcus multilocularis | geminin | 0.0197 | 0.267 | 0.2664 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0046 | 0.045 | 0.1072 |
Echinococcus granulosus | acetylcholinesterase | 0.0273 | 0.3781 | 0.3776 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.3781 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.045 | 0.045 |
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0023 | 0.0109 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0273 | 0.3781 | 1 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.1543 | 0.4068 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0746 | 0.1959 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0389 | 0.0879 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0025 | 0.0145 | 0.0145 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0058 | 0.0631 | 0.1782 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0025 | 0.0145 | 0.0145 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0042 | 0.0389 | 0.101 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.3293 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0377 | 0.0979 |
Schistosoma mansoni | hypothetical protein | 0.0197 | 0.267 | 0.267 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0199 | 0.0507 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0042 | 0.0389 | 0.3108 |
Brugia malayi | Protein arginine N-methyltransferase | 0.0023 | 0.0109 | 0.0269 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.045 | 0.1198 |
Plasmodium vivax | JmjC domain containing protein | 0.0025 | 0.0145 | 0.3613 |
Leishmania major | arginine N-methyltransferase, type I | 0.0023 | 0.0109 | 0.1618 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.1543 | 0.4068 |
Schistosoma mansoni | protein arginine n-methyltransferase | 0.0254 | 0.3506 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0033 | 0.0069 |
Toxoplasma gondii | histone arginine methyltransferase PRMT3 | 0.0023 | 0.0109 | 0.029 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0046 | 0.045 | 0.1072 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0046 | 0.045 | 0.0443 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0109 | 0.0269 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0478 | 0.0478 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0046 | 0.045 | 0.0443 |
Trypanosoma cruzi | protein arginine n-methyltransferase 7 | 0.0023 | 0.0109 | 0.2802 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0389 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0225 | 0.5706 |
Echinococcus granulosus | acetylcholinesterase | 0.0273 | 0.3781 | 0.3776 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0478 | 0.0478 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0025 | 0.0145 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Loa Loa (eye worm) | Carm1-pending protein | 0.0254 | 0.3506 | 0.9273 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0225 | 0.0622 |
Trichomonas vaginalis | esterase, putative | 0.0042 | 0.0389 | 0.0879 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 0.3781 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0273 | 0.3781 | 0.3776 |
Trypanosoma cruzi | arginine N-methyltransferase, type III | 0.0023 | 0.0109 | 0.2802 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0199 | 0.0199 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0029 | 0.0198 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0109 | 0.0269 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.0909 | 0.2389 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0335 | 0.0868 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0025 | 0.0145 | 0.0138 |
Leishmania major | hypothetical protein, conserved | 0.0042 | 0.0389 | 0.5775 |
Brugia malayi | jmjC domain containing protein | 0.0156 | 0.206 | 0.544 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0145 | 0.0365 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0025 | 0.0145 | 0.0138 |
Onchocerca volvulus | 0.0239 | 0.3293 | 1 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0389 | 0.0389 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0821 | 0.2157 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0673 | 0.18 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0205 | 0.5 |
Onchocerca volvulus | 0.0231 | 0.3171 | 0.9605 | |
Schistosoma mansoni | jumonji domain containing protein | 0.0025 | 0.0145 | 0.0145 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0023 | 0.0109 | 0.2802 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0026 | 0.0019 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0145 | 0.2157 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0273 | 0.3781 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0205 | 0.0525 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0673 | 0.0673 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0389 | 0.0879 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.045 | 0.1174 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.043 | 0.1119 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0042 | 0.0389 | 0.1031 |
Echinococcus granulosus | phd:f box containing protein | 0.0025 | 0.0145 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.2867 | 0.7578 |
Loa Loa (eye worm) | protein arginine N-methyltransferase | 0.0023 | 0.0109 | 0.0269 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0026 | 0.0026 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0098 | 0.122 | 0.122 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0046 | 0.045 | 0.0443 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0225 | 0.0218 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0145 | 0.0365 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0033 | 0.0026 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0145 | 0.0365 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.024 | 0.0233 |
Onchocerca volvulus | 0.0046 | 0.045 | 0.0813 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0673 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.045 | 0.1174 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0145 | 0.0365 |
Mycobacterium leprae | conserved hypothetical protein | 0.0042 | 0.0389 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0046 | 0.045 | 0.1198 |
Echinococcus granulosus | peregrin | 0.0032 | 0.024 | 0.0233 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.0145 | 0.0365 |
Brugia malayi | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0023 | 0.0109 | 0.2802 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.045 | 0.1174 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0673 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.024 | 0.0617 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0595 | 0.1557 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0696 | 1 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0478 | 0.0471 |
Mycobacterium tuberculosis | Conserved protein | 0.0042 | 0.0389 | 0.1031 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0205 | 0.0205 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0389 | 0.101 |
Brugia malayi | hypothetical protein | 0.0152 | 0.2013 | 0.5314 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0109 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0098 | 0.122 | 0.3215 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0046 | 0.045 | 0.045 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0156 | 0.206 | 0.2054 |
Echinococcus multilocularis | phd:f box containing protein | 0.0025 | 0.0145 | 0.0138 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.045 | 0.1174 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0205 | 0.0525 |
Leishmania major | arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 | 0.0023 | 0.0109 | 0.1618 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0692 | 0.0692 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0205 | 0.0525 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0007 | 0.0007 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0205 | 0.5191 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0306 | 0.0299 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.0167 | 0.0422 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0341 | 0.0884 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0145 | 0.0365 |
Schistosoma mansoni | gliotactin | 0.0046 | 0.045 | 0.045 |
Brugia malayi | beta-lactamase family protein | 0.0042 | 0.0389 | 0.101 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0042 | 0.0389 | 0.0879 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0025 | 0.0145 | 0.0394 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0042 | 0.0389 | 0.1031 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0025 | 0.0145 | 0.696 |
Echinococcus multilocularis | protein arginine N methyltransferase 7 | 0.0023 | 0.0109 | 0.0102 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0095 | 0.1168 | 0.1161 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0205 | 0.0566 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0335 | 0.0868 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0046 | 0.045 | 0.045 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0673 | 0.1903 |
Echinococcus granulosus | histone arginine methyltransferase CARMER | 0.0254 | 0.3506 | 0.3502 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0225 | 0.0225 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0225 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0595 | 0.1557 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0251 | 0.0244 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0042 | 0.0389 | 0.1031 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0025 | 0.0145 | 0.0138 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.2867 | 0.7578 |
Trypanosoma brucei | Protein arginine N-methyltransferase 1 catalytic subunit | 0.0023 | 0.0109 | 0.0871 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0042 | 0.0389 | 0.0389 |
Schistosoma mansoni | protein phosphatase 2C | 0.0025 | 0.0145 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.045 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0389 | 0.101 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0042 | 0.0389 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0665 | 0.1744 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0156 | 0.206 | 0.2054 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0033 | 0.0069 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0682 | 0.0675 |
Entamoeba histolytica | arginine N-methyltransferase 1, putative | 0.0023 | 0.0109 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0033 | 0.0026 |
Schistosoma mansoni | jumonji domain containing protein | 0.0136 | 0.1769 | 0.1769 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0033 | 0.0026 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0042 | 0.0389 | 0.0382 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.0735 | 0.0735 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0205 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0342 | 0.0886 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0205 | 0.0198 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0145 | 0.0365 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0205 | 1 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0025 | 0.0145 | 0.1161 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0088 | 0.0088 |
Toxoplasma gondii | histone arginine methyltransferase PRMT4/CARM1 | 0.0254 | 0.3506 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.045 | 0.1198 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0673 | 0.0673 |
Brugia malayi | beta-lactamase | 0.0042 | 0.0389 | 0.101 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0088 | 0.008 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0042 | 0.0389 | 0.0879 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0023 | 0.0109 | 0.2802 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0205 | 0.0205 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0033 | 0.0069 |
Mycobacterium leprae | Probable lipase LipE | 0.0042 | 0.0389 | 0.5 |
Loa Loa (eye worm) | beta-lactamase | 0.0042 | 0.0389 | 0.101 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0251 | 0.0251 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0042 | 0.0389 | 0.1031 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0007 | 0.0191 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0595 | 0.1557 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0132 | 0.0124 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0079 | 0.019 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0673 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.0145 | 0.0365 |
Trypanosoma brucei | protein arginine n-methyltransferase 7 | 0.0023 | 0.0109 | 0.0871 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0035 | 0.0073 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0088 | 0.008 |
Onchocerca volvulus | 0.0046 | 0.045 | 0.0813 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0199 | 0.0192 |
Onchocerca volvulus | 0.0046 | 0.045 | 0.0813 | |
Onchocerca volvulus | 0.0042 | 0.0389 | 0.0613 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0273 | 0.3781 | 0.3776 |
Echinococcus granulosus | carboxylesterase 5A | 0.0273 | 0.3781 | 0.3776 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0145 | 0.0365 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 31.25 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as growth inhibition by broth microdilution method | ChEMBL. | No reference |
MIC (functional) | = 250 ug ml-1 | Antifungal activity against Candida albicans ATCC 10231 assessed as growth inhibition by broth microdilution method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.