Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0139 | 0.3932 | 0.6749 |
Echinococcus granulosus | lamin | 0.0028 | 0.0315 | 0.0315 |
Echinococcus granulosus | single minded 2 | 0.0039 | 0.0653 | 0.0653 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0428 | 0.0428 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0065 | 0.1506 | 0.3151 |
Leishmania major | NADPH-cytochrome p450 reductase-like protein | 0.0082 | 0.2046 | 0.3512 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0428 | 0.0428 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0065 | 0.1506 | 0.2021 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0315 | 0.0315 |
Plasmodium vivax | flavodoxin domain containing protein | 0.0072 | 0.1743 | 0.3647 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.1016 | 0.1016 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0158 | 0.0212 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0065 | 0.1506 | 0.2585 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.005 | 0.1028 | 0.1028 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.3567 | 0.3567 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1506 | 0.1506 |
Mycobacterium ulcerans | hypothetical protein | 0.0197 | 0.5826 | 1 |
Echinococcus granulosus | geminin | 0.0164 | 0.4727 | 0.4727 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0043 | 0.0784 | 0.0784 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0057 | 0.1257 | 0.1257 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0024 | 0.0158 | 0.0158 |
Onchocerca volvulus | 0.0028 | 0.0315 | 0.031 | |
Plasmodium falciparum | geranylgeranyl transferase type-2 subunit alpha, putative | 0.0043 | 0.0784 | 0.1639 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0315 | 0.0315 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0315 | 0.0315 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0379 | 0.0651 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1637 | 0.1637 |
Plasmodium vivax | NADPH-cytochrome p450 reductase, putative | 0.0082 | 0.2046 | 0.428 |
Brugia malayi | flavodoxin family protein | 0.0082 | 0.2046 | 0.2745 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0117 | 0.0117 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0191 | 0.0328 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trypanosoma cruzi | cytochrome P450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0057 | 0.1257 | 0.2157 |
Brugia malayi | nuclear receptor NHR-88 | 0.0024 | 0.0158 | 0.0212 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0031 | 0.0403 | 0.0691 |
Echinococcus granulosus | NADPH dependent diflavin oxidoreductase 1 | 0.0082 | 0.2046 | 0.2046 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.1016 | 0.1016 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0031 | 0.0403 | 0.0691 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0197 | 0.5826 | 1 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0031 | 0.0403 | 0.0691 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0158 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.5234 | 0.5234 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0379 | 0.0651 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0139 | 0.3932 | 0.3932 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0379 | 0.0794 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.2046 | 0.2046 |
Schistosoma mansoni | coup transcription factor | 0.0024 | 0.0158 | 0.0158 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.3104 | 0.8821 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.268 | 0.268 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.1016 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0325 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.093 | 0.093 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0139 | 0.3932 | 0.3932 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.0784 | 0.1345 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0065 | 0.1506 | 0.1506 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.1016 | 0.2125 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0024 | 0.0158 | 0.0158 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.093 | 0.093 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0117 | 0.0244 |
Schistosoma mansoni | ran | 0.0022 | 0.0117 | 0.0117 |
Giardia lamblia | Nitric oxide synthase, inducible | 0.0072 | 0.1743 | 0.3647 |
Mycobacterium ulcerans | formate dehydrogenase H FdhF | 0.0082 | 0.2046 | 0.3512 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.352 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0158 | 0.0212 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0315 | 0.0423 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.1016 | 0.2125 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0065 | 0.1506 | 0.2585 |
Brugia malayi | nuclear hormone receptor | 0.0024 | 0.0158 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.478 | 0.478 |
Plasmodium falciparum | polyprenol reductase, putative | 0.0065 | 0.1506 | 0.3151 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0043 | 0.0784 | 0.1639 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | nuclear hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0057 | 0.1257 | 0.1257 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0024 | 0.0158 | 0.0158 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0065 | 0.1506 | 0.2585 |
Trypanosoma cruzi | NADPH--cytochrome P450 reductase, putative | 0.0031 | 0.0403 | 0.0691 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0158 | 0.0158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0065 | 0.1506 | 0.2585 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0158 | 0.0158 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0165 | 0.478 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0158 | 0.0212 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.0197 | 0.5826 | 0.7816 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.093 | 0.093 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0057 | 0.1257 | 0.1257 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0191 | 0.0328 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0031 | 0.0403 | 0.0691 |
Trypanosoma cruzi | p450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0117 | 0.0157 |
Plasmodium falciparum | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0031 | 0.0403 | 0.0843 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.268 | 0.3595 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0022 | 0.0117 | 0.02 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.268 | 0.268 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0031 | 0.0403 | 0.0691 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0024 | 0.0158 | 0.0212 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0043 | 0.0784 | 0.1051 |
Plasmodium falciparum | NADPH--cytochrome P450 reductase, putative | 0.0031 | 0.0403 | 0.0843 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0197 | 0.5826 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0197 | 0.5826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.1518 | 0.2606 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.1016 | 0.1743 |
Brugia malayi | ecdysteroid receptor | 0.0179 | 0.5234 | 0.7022 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1637 | 0.1637 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0428 | 0.0574 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.3104 | 0.8821 |
Giardia lamblia | Hypothetical protein | 0.0072 | 0.1743 | 0.3647 |
Trichomonas vaginalis | NADPH cytochrome P450, putative | 0.0031 | 0.0403 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1257 | 0.1257 |
Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.0043 | 0.0784 | 0.0784 |
Brugia malayi | RNA, U transporter 1 | 0.0087 | 0.2213 | 0.2968 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0165 | 0.478 | 0.478 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0165 | 0.478 | 0.8204 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0065 | 0.1506 | 0.2585 |
Leishmania major | trypanothione reductase | 0.005 | 0.1016 | 0.1743 |
Mycobacterium ulcerans | putative regulatory protein | 0.0039 | 0.0653 | 0.1121 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.352 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0379 | 0.0379 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0022 | 0.0117 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.5133 | 0.5133 |
Echinococcus multilocularis | geminin | 0.0164 | 0.4727 | 0.4727 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0158 | 0.0212 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | flavodoxin family protein | 0.0031 | 0.0403 | 0.054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0428 | 0.0428 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0158 | 0.0212 |
Schistosoma mansoni | cytochrome P450 reductase | 0.0082 | 0.2046 | 0.2046 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0428 | 0.0428 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0197 | 0.5826 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0325 | 1 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0165 | 0.478 | 0.8204 |
Trypanosoma brucei | NADPH-cytochrome p450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0315 | 0.0315 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0197 | 0.5826 | 1 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0197 | 0.5826 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0298 | 0.0298 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.352 | 1 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0065 | 0.1506 | 0.1506 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0197 | 0.5826 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.06 | 0.06 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0065 | 0.1506 | 0.1506 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3567 | 0.3567 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0158 | 0.0212 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0162 | 0.4688 | 0.4688 |
Brugia malayi | follicle stimulating hormone receptor | 0.0247 | 0.7454 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0158 | 0.0212 |
Leishmania major | GTP-binding protein, putative | 0.0022 | 0.0117 | 0.02 |
Onchocerca volvulus | 0.0043 | 0.0784 | 0.1233 | |
Schistosoma mansoni | lamin | 0.0028 | 0.0315 | 0.0315 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0024 | 0.0158 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0428 | 0.0428 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0043 | 0.0784 | 0.0784 |
Schistosoma mansoni | NADPH flavin oxidoreductase | 0.0041 | 0.0726 | 0.0726 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.5826 | 0.5826 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.3104 | 0.8821 |
Schistosoma mansoni | single-minded | 0.0052 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.3932 | 0.3932 |
Echinococcus granulosus | methionine synthase reductase | 0.005 | 0.1028 | 0.1028 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0428 | 0.0428 |
Brugia malayi | hypoxia-induced factor 1 | 0.0162 | 0.4688 | 0.6289 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | lamin | 0.0028 | 0.0315 | 0.0315 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3567 | 0.3567 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0428 | 0.0574 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0139 | 0.3932 | 0.5275 |
Echinococcus multilocularis | NADPH dependent diflavin oxidoreductase 1 | 0.0082 | 0.2046 | 0.2046 |
Toxoplasma gondii | hypothetical protein | 0.0122 | 0.3381 | 0.5804 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0165 | 0.478 | 1 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0065 | 0.1506 | 0.1506 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0191 | 0.0328 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0117 | 0.0117 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.3567 | 0.3567 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0031 | 0.0403 | 0.0691 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.0043 | 0.0784 | 0.1345 |
Trypanosoma cruzi | NADPH-dependent FMN/FAD containing oxidoreductase, putative | 0.0082 | 0.2046 | 0.3512 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0191 | 0.0328 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0024 | 0.0158 | 0.0158 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0043 | 0.0784 | 0.1345 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0165 | 0.478 | 0.478 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0191 | 0.0328 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0065 | 0.1506 | 0.2585 |
Brugia malayi | FAD binding domain containing protein | 0.0082 | 0.2046 | 0.2745 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0158 | 0.0158 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.004 | 0.0705 | 0.1211 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0065 | 0.1506 | 0.1506 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.1016 | 0.1016 |
Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.0043 | 0.0784 | 0.0784 |
Echinococcus multilocularis | methionine synthase reductase | 0.005 | 0.1028 | 0.1028 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.093 | 0.1248 |
Onchocerca volvulus | 0.0028 | 0.0315 | 0.031 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.093 | 0.093 |
Schistosoma mansoni | thyroid hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0428 | 0.0428 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0065 | 0.1506 | 0.1506 |
Echinococcus multilocularis | NADPH cytochrome P450 reductase | 0.0082 | 0.2046 | 0.2046 |
Brugia malayi | bHLH-PAS transcription factor | 0.0039 | 0.0653 | 0.0876 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.1016 | 0.2125 |
Trichomonas vaginalis | sulfite reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0065 | 0.1506 | 0.2585 |
Toxoplasma gondii | flavodoxin domain-containing protein | 0.004 | 0.0705 | 0.1211 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.0065 | 0.1506 | 0.2585 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0428 | 0.0428 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0139 | 0.3932 | 0.6749 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.4727 | 0.4727 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0057 | 0.1257 | 0.1257 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.093 | 0.093 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0065 | 0.1506 | 0.2585 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.3104 | 0.8821 |
Echinococcus multilocularis | snurportin 1 | 0.0325 | 1 | 1 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0122 | 0.3381 | 0.5804 |
Schistosoma mansoni | 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase | 0.005 | 0.1028 | 0.1028 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.352 | 1 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0191 | 0.0328 |
Leishmania major | p450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0139 | 0.3932 | 0.6749 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0315 | 0.0315 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0031 | 0.0403 | 0.0691 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0165 | 0.478 | 0.478 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0158 | 0.0158 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.1518 | 0.2606 |
Onchocerca volvulus | 0.0039 | 0.0653 | 0.0976 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0158 | 0.0158 |
Echinococcus granulosus | NADPH cytochrome P450 reductase | 0.0082 | 0.2046 | 0.2046 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3567 | 0.3567 |
Leishmania major | cytochrome P450 reductase, putative | 0.0072 | 0.1743 | 0.2993 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.06 | 0.103 |
Brugia malayi | glutathione reductase | 0.005 | 0.1016 | 0.1362 |
Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1639 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0379 | 0.0379 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0024 | 0.0158 | 0.0212 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.093 | 0.093 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0024 | 0.0158 | 0.0158 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0057 | 0.1257 | 0.1257 |
Schistosoma mansoni | thyroid hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0117 | 0.02 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0165 | 0.478 | 0.6413 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0117 | 0.0244 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0039 | 0.0653 | 0.0653 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0158 | 0.0212 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.06 | 0.103 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0165 | 0.478 | 0.478 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0065 | 0.1506 | 0.3151 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0428 | 0.0428 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.1016 | 0.1743 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0139 | 0.3932 | 0.3932 |
Schistosoma mansoni | ran | 0.0022 | 0.0117 | 0.0117 |
Trypanosoma cruzi | Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative | 0.0031 | 0.0403 | 0.0691 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.0065 | 0.1506 | 0.2585 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1506 | 0.1506 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.0065 | 0.1518 | 0.2606 |
Trypanosoma brucei | NADPH--cytochrome P450 reductase, putative | 0.0082 | 0.2046 | 0.3512 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0784 | 0.1345 |
Trichomonas vaginalis | ran, putative | 0.0022 | 0.0117 | 0.02 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.3567 | 0.3567 |
Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.0043 | 0.0784 | 0.0784 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0 | 0.5 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0197 | 0.5826 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0315 | 0.0315 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0428 | 0.0428 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.0784 | 0.1345 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0024 | 0.0158 | 0.0158 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.06 | 0.06 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0165 | 0.478 | 1 |
Loa Loa (eye worm) | FAD binding domain-containing protein | 0.0082 | 0.2046 | 0.2046 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.0043 | 0.0784 | 0.1345 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.3567 | 0.3567 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0117 | 0.02 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0139 | 0.3932 | 0.6749 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0024 | 0.0158 | 0.0158 |
Leishmania major | protein farnesyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.0403 | 0.0691 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.3567 | 0.4785 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0024 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0158 | 0.0158 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0031 | 0.0403 | 0.0691 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.3104 | 0.8821 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0315 | 0.0315 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0428 | 0.0428 |
Brugia malayi | PAS domain containing protein | 0.0052 | 0.1098 | 0.1473 |
Brugia malayi | FAD binding domain containing protein | 0.005 | 0.1028 | 0.1379 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | steroid hormone receptor | 0.0024 | 0.0158 | 0.0212 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.06 | 0.103 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0024 | 0.0158 | 0.0212 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0247 | 0.7454 | 0.7454 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0197 | 0.5826 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0065 | 0.1506 | 0.2585 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0117 | 0.0117 |
Trichomonas vaginalis | NADPH fad oxidoreductase, putative | 0.0072 | 0.1743 | 0.2993 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0784 | 0.1345 |
Plasmodium falciparum | nitric oxide synthase, putative | 0.0082 | 0.2046 | 0.428 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0031 | 0.0403 | 0.0691 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0158 | 0.0212 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0379 | 0.0651 |
Echinococcus granulosus | FTZ F1 alpha | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0158 | 0.0212 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.093 | 0.093 |
Schistosoma mansoni | diflavin oxidoreductase | 0.004 | 0.0705 | 0.0705 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0024 | 0.0158 | 0.0158 |
Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.0043 | 0.0784 | 0.0784 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0158 | 0.0212 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0158 | 0.0158 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.1016 | 0.1743 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Entamoeba histolytica | hypothetical protein | 0.0065 | 0.1506 | 0.2585 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.0065 | 0.1518 | 0.3176 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0379 | 0.0379 |
Entamoeba histolytica | Rab geranylgeranyltransferase alpha subunit, putative | 0.0043 | 0.0784 | 0.1345 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0158 | 0.0158 |
Treponema pallidum | flavodoxin | 0.0031 | 0.0403 | 1 |
Plasmodium vivax | polyprenol reductase, putative | 0.0065 | 0.1506 | 0.3151 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0403 | 0.0843 |
Schistosoma mansoni | patched 1 | 0.0057 | 0.1257 | 0.1257 |
Brugia malayi | RNA binding protein | 0.0128 | 0.3567 | 0.4785 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.1637 | 0.2197 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | hypothetical protein | 0.0176 | 0.5133 | 0.6886 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0379 | 0.0379 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0165 | 0.478 | 0.8204 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3567 | 0.3567 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0057 | 0.1257 | 0.1257 |
Onchocerca volvulus | 0.0065 | 0.1506 | 0.2656 | |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0065 | 0.1506 | 0.3151 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.06 | 0.103 |
Brugia malayi | CHE-14 protein | 0.0057 | 0.1257 | 0.1686 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0428 | 0.0428 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0024 | 0.0158 | 0.0158 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.3567 | 0.4785 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0052 | 0.1098 | 0.1098 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0315 | 0.0423 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.4727 | 0.4727 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0379 | 0.0794 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0022 | 0.0117 | 0.02 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.3567 | 0.3567 |
Loa Loa (eye worm) | flavodoxin family protein | 0.0031 | 0.0403 | 0.0403 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0379 | 0.0509 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.1016 | 0.1016 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.093 | 0.093 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0139 | 0.3932 | 0.6749 |
Entamoeba histolytica | Ran family GTPase | 0.0022 | 0.0117 | 0.02 |
Trypanosoma brucei | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative | 0.0031 | 0.0403 | 0.0691 |
Brugia malayi | hypothetical protein | 0.0037 | 0.06 | 0.0805 |
Echinococcus multilocularis | protein patched | 0.0057 | 0.1257 | 0.1257 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.06 | 0.06 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0065 | 0.1506 | 0.2585 |
Echinococcus multilocularis | protein dispatched 1 | 0.0057 | 0.1257 | 0.1257 |
Trypanosoma brucei | NADPH-dependent diflavin oxidoreductase 1 | 0.0082 | 0.2046 | 0.3512 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0165 | 0.478 | 0.8204 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.06 | 0.06 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0057 | 0.1257 | 0.1257 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.1016 | 0.2125 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0158 | 0.0158 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.3104 | 0.8821 |
Chlamydia trachomatis | sulfite reductase | 0.005 | 0.1028 | 0.5 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0179 | 0.5234 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.3567 | 0.3567 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.268 | 0.3595 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.1016 | 0.2885 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.