Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.0296 | 0.982 | 0.9813 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.1407 | 0.1407 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.039 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0756 | 0.0756 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.039 | 0.039 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0128 | 0.3894 | 0.3646 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.5455 | 0.5455 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0128 | 0.3894 | 0.3646 |
Brugia malayi | hypothetical protein | 0.0029 | 0.039 | 0.2768 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.0178 | 0.5635 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0756 | 0.0756 |
Mycobacterium ulcerans | hypothetical protein | 0.0178 | 0.5635 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1407 | 0.1407 |
Onchocerca volvulus | 0.0301 | 1 | 0.5 | |
Giardia lamblia | Hypothetical protein | 0.0178 | 0.5635 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.039 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.1407 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.0128 | 0.3894 | 0.3646 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0178 | 0.5635 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.039 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.1407 | 1 |
Giardia lamblia | Hypothetical protein | 0.0178 | 0.5635 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0296 | 0.982 | 0.9813 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0756 | 0.5371 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0301 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0296 | 0.982 | 0.9813 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.039 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0296 | 0.982 | 0.982 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.0301 | 1 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0128 | 0.3894 | 0.3646 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0021 | 0.0147 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.0296 | 0.982 | 0.9813 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0301 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0301 | 1 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.0301 | 1 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0301 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.