Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | mitochondrial DNA topoisomerase II | 0.0421 | 0.0487 | 0.0485 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0421 | 0.0487 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0421 | 0.0487 | 0.0485 |
Schistosoma mansoni | P2X receptor subunit | 0.0282 | 0.0302 | 0.0302 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1432 | 0.1833 | 0.1832 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0421 | 0.0487 | 0.0487 |
Plasmodium falciparum | heat shock protein 90 | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Trichomonas vaginalis | sensory transduction histidine kinase, putative | 0.0421 | 0.0487 | 1 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0057 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.7567 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0421 | 0.0487 | 1 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0421 | 0.0487 | 0.1104 |
Mycobacterium ulcerans | hypothetical protein | 0.1981 | 0.2564 | 1 |
Trypanosoma brucei | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.2645 | 0.3448 | 0.3447 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Two component sensor kinase MprB | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0421 | 0.0487 | 0.1893 |
Loa Loa (eye worm) | hypothetical protein | 0.7567 | 1 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0833 | 0.1036 | 0.1036 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium ulcerans | sensor kinase from two component regulatory system | 0.0421 | 0.0487 | 0.1893 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.1893 |
Leishmania major | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.2645 | 0.3448 | 0.3447 |
Mycobacterium ulcerans | two component system membrane associated sensor kinase | 0.0421 | 0.0487 | 0.1893 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0421 | 0.0487 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.3357 | 0.4396 | 0.4396 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium tuberculosis | Two component sensor kinase [second part] | 0.0421 | 0.0487 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0421 | 0.0487 | 0.121 |
Echinococcus multilocularis | heat shock protein | 0.0421 | 0.0487 | 0.0487 |
Mycobacterium tuberculosis | Two component sensory transduction histidine kinase MtrB | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.0118 | 0.0118 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0421 | 0.0487 | 0.0485 |
Onchocerca volvulus | 0.3357 | 0.4396 | 1 | |
Leishmania major | DNA topoisomerase ii | 0.0421 | 0.0487 | 0.0485 |
Giardia lamblia | Hypothetical protein | 0.1981 | 0.2564 | 1 |
Schistosoma mansoni | endoplasmin | 0.0421 | 0.0487 | 0.0487 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0421 | 0.0487 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0421 | 0.0487 | 0.0487 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3357 | 0.4396 | 0.4395 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0144 | 0.0118 | 0.0118 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1432 | 0.1833 | 0.1832 |
Leishmania major | hypothetical protein, conserved | 0.0421 | 0.0487 | 0.0485 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0421 | 0.0487 | 0.121 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Treponema pallidum | chemotaxis histidine kinase (cheA) | 0.0421 | 0.0487 | 1 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0421 | 0.0487 | 0.1893 |
Plasmodium falciparum | endoplasmin, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | TKL/MLK/LZK protein kinase | 0.013 | 0.0099 | 0.0099 |
Trichomonas vaginalis | sensor histidine kinase, putative | 0.0421 | 0.0487 | 1 |
Leishmania major | developmentally regulated phosphoprotein-like protein | 0.7567 | 1 | 1 |
Schistosoma mansoni | heat shock protein | 0.0421 | 0.0487 | 0.0487 |
Mycobacterium ulcerans | two component sensory transduction histidine kinase MtrB | 0.0421 | 0.0487 | 0.1893 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.0421 | 0.0487 | 0.1893 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.7567 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0282 | 0.0302 | 0.0302 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Plasmodium vivax | heat shock protein 86, putative | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1432 | 0.1833 | 0.1832 |
Schistosoma mansoni | P2X receptor subunit | 0.0282 | 0.0302 | 0.0302 |
Mycobacterium ulcerans | two component sensor kinase MprB | 0.0421 | 0.0487 | 0.1893 |
Mycobacterium tuberculosis | Probable two component sensor kinase | 0.0421 | 0.0487 | 1 |
Giardia lamblia | Hypothetical protein | 0.1981 | 0.2564 | 1 |
Mycobacterium ulcerans | two component sensor histidine kinase SenX3 | 0.0421 | 0.0487 | 0.1893 |
Brugia malayi | heat shock protein 90 | 0.0421 | 0.0487 | 0.0487 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.33 | 0.432 | 0.4319 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Brugia malayi | Protein kinase domain containing protein | 0.013 | 0.0099 | 0.0099 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3357 | 0.4396 | 0.4396 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0833 | 0.1036 | 0.1036 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.1893 |
Mycobacterium tuberculosis | Possible two component sensor kinase | 0.0421 | 0.0487 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium ulcerans | two component regulator - sensor kinase | 0.0421 | 0.0487 | 0.1893 |
Mycobacterium tuberculosis | Conserved protein | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | heat shock protein | 0.0421 | 0.0487 | 0.0487 |
Plasmodium vivax | hypothetical protein, conserved | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | pyruvate dehydrogenase (lipoamide) kinase, putative | 0.2645 | 0.3448 | 0.3447 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium ulcerans | two component system response phosphate sensor kinase, PhoR | 0.0421 | 0.0487 | 0.1893 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.0487 | 0.0487 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.33 | 0.432 | 0.4319 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0421 | 0.0487 | 0.0487 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.121 |
Schistosoma mansoni | DNA topoisomerase II | 0.0421 | 0.0487 | 0.0487 |
Echinococcus granulosus | heat shock protein 90 | 0.0421 | 0.0487 | 0.0487 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.7146 | 0.944 | 0.944 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3357 | 0.4396 | 0.4395 |
Mycobacterium ulcerans | two component sensor histidine kinase TrcS | 0.0421 | 0.0487 | 0.1893 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1432 | 0.1833 | 0.1832 |
Mycobacterium tuberculosis | Probable sensor protein KdpD | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0421 | 0.0487 | 0.0487 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0421 | 0.0487 | 1 |
Brugia malayi | UBASH3A protein homolog | 0.0057 | 0.0002 | 0.0002 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.0118 | 0.0118 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0099 | 0.0099 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.33 | 0.432 | 0.432 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0421 | 0.0487 | 0.1104 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0421 | 0.0487 | 0.5 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0421 | 0.0487 | 1 |
Mycobacterium leprae | TWO COMPONENT SENSOR HISTIDINE KINASE PRRB | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.7567 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0057 | 0.0002 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | signal transduction histidine kinase and receiver | 0.0421 | 0.0487 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.0099 | 0.0099 |
Trichomonas vaginalis | two component sensor and regulator histidine kinase bacteria, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma cruzi | developmentally regulated phosphoprotein, putative | 0.7567 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | membrane associated signal transduction histidine kinase | 0.0421 | 0.0487 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0132 | 0.0102 | 0.0102 |
Mycobacterium ulcerans | putative regultory protein | 0.0421 | 0.0487 | 0.1893 |
Trichomonas vaginalis | sensory transduction histidine kinase bacterial, putative | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.7567 | 1 | 1 |
Mycobacterium leprae | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.33 | 0.432 | 0.4319 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium tuberculosis | Possible two component sensor kinase TcrY | 0.0421 | 0.0487 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.0487 | 0.0487 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.0485 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.33 | 0.432 | 0.4319 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Schistosoma mansoni | heat shock protein | 0.0421 | 0.0487 | 0.0487 |
Mycobacterium leprae | Probable two-component sensor kinase | 0.0421 | 0.0487 | 1 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0421 | 0.0487 | 1 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0057 | 0.0002 | 0.0002 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0421 | 0.0487 | 0.121 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0057 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | two component sensor histidine kinase PrrB | 0.0421 | 0.0487 | 0.1893 |
Echinococcus granulosus | 6 phosphofructo 2 kinase:fructose 2 | 0.3357 | 0.4396 | 0.4396 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0833 | 0.1036 | 0.1036 |
Plasmodium falciparum | DNA topoisomerase VI, b subunit, putative | 0.0421 | 0.0487 | 1 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.3066 | 0.4008 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase kinase, putative | 0.2645 | 0.3448 | 0.8601 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.1981 | 0.2564 | 1 |
Schistosoma mansoni | endoplasmin | 0.0421 | 0.0487 | 0.0487 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0421 | 0.0487 | 0.0485 |
Trichomonas vaginalis | endoplasmin, putative | 0.0421 | 0.0487 | 1 |
Trichomonas vaginalis | receptor histidine kinase, putative | 0.0421 | 0.0487 | 1 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0421 | 0.0487 | 1 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.0421 | 0.0487 | 1 |
Brugia malayi | Endoplasmin precursor | 0.0421 | 0.0487 | 0.0487 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.7146 | 0.944 | 0.944 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0002 | 0.0002 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0282 | 0.0302 | 0.0302 |
Trichomonas vaginalis | mismatch repair protein Mlh1C (mutL homolog) | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0057 | 0.0002 | 0.0002 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3357 | 0.4396 | 0.4395 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3357 | 0.4396 | 0.4395 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0421 | 0.0487 | 0.1104 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0421 | 0.0487 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.013 | 0.0099 | 0.0099 |
Echinococcus multilocularis | heat shock protein 90 | 0.0421 | 0.0487 | 0.0487 |
Brugia malayi | Probable DNA topoisomerase II | 0.0421 | 0.0487 | 0.0487 |
Trypanosoma cruzi | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative | 0.0421 | 0.0487 | 0.0485 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0421 | 0.0487 | 0.0485 |
Plasmodium vivax | endoplasmin, putative | 0.0421 | 0.0487 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0282 | 0.0302 | 0.0302 |
Trypanosoma brucei | heat shock protein, putative | 0.0421 | 0.0487 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.1925 | 0.2489 | 0.2489 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0421 | 0.0487 | 0.121 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0421 | 0.0487 | 0.0487 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0421 | 0.0487 | 1 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.1981 | 0.2564 | 1 |
Mycobacterium tuberculosis | Two component sensor histidine kinase PrrB | 0.0421 | 0.0487 | 1 |
Mycobacterium leprae | Probable two component sensor kinase MprB | 0.0421 | 0.0487 | 1 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.013 | 0.0099 | 0.0099 |
Mycobacterium tuberculosis | Possible two component system response sensor kinase membrane associated PhoR | 0.0421 | 0.0487 | 1 |
Trypanosoma brucei | developmentally regulated phosphoprotein | 0.7567 | 1 | 1 |
Mycobacterium tuberculosis | Two component sensor histidine kinase TrcS | 0.0421 | 0.0487 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0421 | 0.0487 | 0.0485 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0057 | 0.0002 | 0.0002 |
Leishmania major | heat shock protein 83-1 | 0.0421 | 0.0487 | 0.0485 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.0421 | 0.0487 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3357 | 0.4396 | 0.4396 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0421 | 0.0487 | 0.0485 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0057 | 0.0002 | 0.0002 |
Trichomonas vaginalis | heat shock protein, putative | 0.0421 | 0.0487 | 1 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0421 | 0.0487 | 0.0487 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.