Detailed information for compound 1797897

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 548.39 | Formula: C21H30FIN4O4
  • H donors: 1 H acceptors: 3 LogP: 1.78 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 2
  • SMILES: FCCOCCOCCOCCN(CCNC(=O)c1cnc2c(n1)ccc(c2)I)CC
  • InChi: 1S/C21H30FIN4O4/c1-2-27(8-10-30-12-14-31-13-11-29-9-5-22)7-6-24-21(28)20-16-25-19-15-17(23)3-4-18(19)26-20/h3-4,15-16H,2,5-14H2,1H3,(H,24,28)
  • InChiKey: UTCCSNWUOVPLPB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0027 0.005 0.0046
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0015 0.0011
Trichomonas vaginalis rotamase, putative 0.0037 0.0101 0.0305
Echinococcus granulosus notch 0.0116 0.0516 0.0512
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.003 0.0026
Entamoeba histolytica tyrosyl-tRNA synthetase, putative 0.0033 0.0081 0.0097
Plasmodium falciparum phosphoglycerate mutase, putative 0.0032 0.0079 0.14
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0034 0.003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0322 0.1598 0.1594
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0034 0.003
Echinococcus multilocularis neurogenic locus protein delta 0.0116 0.0516 0.0512
Trypanosoma cruzi tyrosyl-tRNA synthetase, putative 0.0033 0.0081 0.0076
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0022 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0191 0.091 0.0906
Loa Loa (eye worm) Notch2 0.0116 0.0516 0.0512
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0271 0.133 0.1326
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0032 0.0079 0.0075
Echinococcus multilocularis protein jagged 1 0.0116 0.0516 0.0512
Onchocerca volvulus 0.0191 0.091 0.0893
Onchocerca volvulus 0.0892 0.4585 0.4575
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0087 0.0363 0.7161
Schistosoma mansoni hypothetical protein 0.029 0.1428 0.1424
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0345 0.1719 0.1715
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0101 0.0305
Schistosoma mansoni hypothetical protein 0.0058 0.0214 0.021
Mycobacterium tuberculosis Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0103 0.0451 0.0788
Brugia malayi nuclear hormone receptor 0.0024 0.0034 0.003
Onchocerca volvulus Fxna peptidase homolog 0.0023 0.0029 0.001
Mycobacterium tuberculosis Glucosyl-3-phosphoglycerate phosphatase GpgP 0.0032 0.0079 0.0138
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0034 0.003
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.0618 0.0614
Brugia malayi UBASH3A protein homolog 0.0032 0.0079 0.0075
Echinococcus granulosus histone lysine methyltransferase setb 0.0071 0.028 0.0276
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0042 0.0095
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.1891 0.983 0.983
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0071 0.028 0.0276
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0821 0.4214 0.4212
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Echinococcus multilocularis neuropeptide s receptor 0.0515 0.261 0.2606
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Echinococcus granulosus protein jagged 2 0.0116 0.0516 0.0512
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0044 0.004
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0087 0.0363 0.0359
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0027 0.005 0.0046
Toxoplasma gondii peptidylprolyl isomerase 0.0036 0.0097 0.1511
Brugia malayi Pre-SET motif family protein 0.0071 0.028 0.0279
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0026 0.0044 0.004
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.003 0.0026
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0134 0.0609 0.1065
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0034 0.003
Mycobacterium ulcerans hypothetical protein 0.0023 0.0029 0.0042
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0026 0.0044 0.004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0122 0.0118
Echinococcus granulosus lysine specific demethylase 5A 0.0121 0.0543 0.0539
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Brugia malayi Cytochrome P450 family protein 0.0037 0.0101 0.0098
Echinococcus granulosus metabotropic glutamate receptor 2 0.0189 0.0898 0.0895
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0122 0.0377
Echinococcus granulosus geminin 0.029 0.1428 0.1424
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0045 0.0142 0.014
Mycobacterium ulcerans glutaminase 0.0139 0.0635 0.1076
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0618 0.1047
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Schistosoma mansoni tyrosyl-tRNA synthetase 0.0058 0.0214 0.021
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Brugia malayi FXNA 0.0023 0.0029 0.0025
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0032 0.006
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0093 0.0398 0.0394
Plasmodium vivax JmjC domain containing protein 0.0032 0.0078 0.1379
Mycobacterium ulcerans fructose-2,6-bisphosphatase GpmB 0.1135 0.5864 1
Brugia malayi glutathione reductase 0.0059 0.0215 0.0214
Echinococcus granulosus expressed protein 0.0037 0.0101 0.0097
Brugia malayi phosphoglycerate mutase family protein 0.0032 0.0079 0.0075
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.003 0.0026
Echinococcus multilocularis fibropellin Ia 0.0116 0.0516 0.0512
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0015
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.0618 0.0614
Brugia malayi thymidylate synthase 0.008 0.0331 0.033
Mycobacterium leprae Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0032 0.0079 0.0138
Onchocerca volvulus 0.0116 0.0516 0.0498
Loa Loa (eye worm) inositol-1 0.0041 0.0122 0.0118
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0078 0.0074
Toxoplasma gondii methionyl-tRNA synthetase 0.0025 0.0042 0.0613
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0025 0.0042 0.0038
Echinococcus multilocularis neurogenic locus protein delta 0.0116 0.0516 0.0512
Trichomonas vaginalis Clan MH, family M28, aminopeptidase S-like metallopeptidase 0.0023 0.0029 0.005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0034 0.003
Onchocerca volvulus Neurogenic locus notch homolog 0.0116 0.0516 0.0498
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0078 0.0074
Echinococcus multilocularis slit 2 protein 0.0116 0.0516 0.0512
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.003 0.0026
Giardia lamblia Rrm3p helicase 0.0022 0.0024 0.0016
Trypanosoma cruzi extracellular receptor, putative 0.0026 0.0044 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.002 0.0015 0.0011
Echinococcus multilocularis notch 0.0116 0.0516 0.0512
Schistosoma mansoni rotamase 0.0037 0.0101 0.0097
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0543 0.0539
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.003 0.0053
Trypanosoma cruzi glutaminyl cyclase, putative 0.0023 0.0029 0.0025
Treponema pallidum phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) 0.0039 0.0114 1
Plasmodium vivax SET domain protein, putative 0.0071 0.028 0.5484
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0018 0.0004 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0042 0.0095
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0018 0.0004 0.0007
Brugia malayi Calcium binding EGF domain containing protein 0.0116 0.0516 0.0518
Trypanosoma brucei RNA helicase, putative 0.0021 0.002 0.0016
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0027 0.005 0.0046
Onchocerca volvulus 0.0032 0.0079 0.006
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Echinococcus multilocularis neurogenic locus notch protein 4 0.0116 0.0516 0.0512
Mycobacterium tuberculosis Probable lipoprotein aminopeptidase LpqL 0.0031 0.0073 0.0128
Toxoplasma gondii peptidase, M28 family protein 0.0023 0.0029 0.0404
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0122 0.2458
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0015 0.0011
Loa Loa (eye worm) RecQ helicase 0.0024 0.0032 0.0028
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0078 0.0074
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0189 0.0898 0.0895
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0394
Onchocerca volvulus Protein UBASH3A homolog 0.0032 0.0079 0.006
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0618 0.0614
Schistosoma mansoni regulator of G protein signaling 0.0023 0.003 0.0026
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Echinococcus granulosus glutamate receptor 2 0.0026 0.0044 0.004
Plasmodium vivax glutathione reductase, putative 0.0059 0.0215 0.4174
Echinococcus multilocularis thymidylate synthase 0.008 0.0331 0.0327
Trypanosoma cruzi phosphoglycerate mutase, putative 0.0032 0.0079 0.0075
Brugia malayi jmjC domain containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0394
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.003 0.0026
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0029 0.005
Schistosoma mansoni hypothetical protein 0.0027 0.005 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0018 0.0004 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0029 0.005
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0075
Echinococcus multilocularis protein jagged 1 0.0116 0.0516 0.0512
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0099 0.0174
Mycobacterium ulcerans bifunctional RNase H/acid phosphatase 0.0032 0.0079 0.0127
Echinococcus multilocularis 6 phosphofructo 2 kinase:fructose 2 0.1924 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0034 0.003
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0032 0.0079 0.0225
Loa Loa (eye worm) hypothetical protein 0.01 0.0433 0.0429
Echinococcus multilocularis expressed protein 0.0037 0.0101 0.0097
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0121 0.0543 0.0539
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.007 0.0278 0.0274
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Onchocerca volvulus 0.0116 0.0516 0.0498
Echinococcus multilocularis GPCR, family 2 0.0027 0.005 0.0046
Loa Loa (eye worm) hypothetical protein 0.0354 0.1763 0.1759
Schistosoma mansoni laminin gamma-3 chain 0.0116 0.0516 0.0512
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0101 0.0305
Toxoplasma gondii calcium binding egf domain-containing protein 0.0093 0.0398 0.6425
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.003 0.0026
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0078 0.0074
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0101 0.0097
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Plasmodium falciparum phosphoglucomutase-2 0.0032 0.0079 0.14
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0018 0.0004 0.0007
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.003 0.0026
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0034 0.003
Mycobacterium tuberculosis Conserved protein 0.0023 0.0029 0.0051
Brugia malayi Kringle domain containing protein 0.0113 0.0502 0.0504
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Trichomonas vaginalis set domain proteins, putative 0.0562 0.2857 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0034 0.003
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0036 0.0097 0.0093
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.003 0.0026
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0034 0.003
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.003 0.0026
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.003 0.0026
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Onchocerca volvulus Fxna peptidase homolog 0.0023 0.0029 0.001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0078 0.0074
Echinococcus multilocularis tyrosine kinase 0.0026 0.0044 0.004
Schistosoma mansoni glutamate receptor NMDA 0.0026 0.0044 0.004
Echinococcus granulosus neurogenic locus notch protein 4 0.0116 0.0516 0.0512
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Echinococcus granulosus neurogenic locus protein delta 0.0116 0.0516 0.0512
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0085 0.0355 0.0351
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0078 0.0074
Loa Loa (eye worm) latrophilin receptor protein 2 0.0027 0.005 0.0046
Mycobacterium ulcerans hypothetical protein 0.0191 0.091 0.1546
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0032 0.0079 0.0225
Onchocerca volvulus Protein UBASH3A homolog 0.0032 0.0079 0.006
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0101 0.0098
Mycobacterium tuberculosis Probable conserved lipoprotein LpqD 0.0032 0.0079 0.0138
Schistosoma mansoni hypothetical protein 0.0027 0.005 0.0046
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0122 0.0377
Echinococcus granulosus GPCR family 3 C terminal 0.0045 0.0142 0.0138
Schistosoma mansoni sodium/chloride dependent transporter 0.0021 0.0019 0.0015
Plasmodium vivax thioredoxin reductase, putative 0.0059 0.0215 0.4174
Chlamydia trachomatis 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 0.0032 0.0079 0.6416
Echinococcus granulosus tissue type plasminogen activator 0.0113 0.0502 0.0498
Toxoplasma gondii thioredoxin reductase 0.0059 0.0215 0.3443
Plasmodium falciparum tRNA import protein tRIP 0.0025 0.0042 0.0651
Brugia malayi hypothetical protein 0.0023 0.003 0.0026
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0034 0.003
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0821 0.4214 0.4212
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0034 0.003
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.003 0.0026
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0015
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0034 0.003
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0032 0.0079 0.0075
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0029 0.005
Loa Loa (eye worm) norepinephrine transporter 0.0021 0.0019 0.0015
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.002 0.0015 0.0026
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0034 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0079 0.0225
Onchocerca volvulus Glutaminyl cyclase homolog 0.0023 0.0029 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.001 0.0006
Onchocerca volvulus Arrow homolog 0.0093 0.0398 0.038
Onchocerca volvulus Fxna peptidase homolog 0.0023 0.0029 0.001
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0034 0.003
Onchocerca volvulus Poor gastrulation protein homolog 0.0045 0.0142 0.0124
Echinococcus multilocularis fat cadherin tumor suppressor 0.0116 0.0516 0.0512
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Echinococcus granulosus phosphoglycerate mutase 0.0032 0.0079 0.0075
Treponema pallidum phosphoglyceromutase 0.0032 0.0079 0.6416
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0025
Leishmania major extracellular receptor, putative 0.0026 0.0044 0.004
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.002 0.0015 0.0011
Echinococcus multilocularis GPCR, family 3, C terminal 0.0045 0.0142 0.0138
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0044 0.004
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.003 0.0026
Brugia malayi hypothetical protein 0.0038 0.0109 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1902 0.9886 0.9886
Leishmania major hypothetical protein, unknown function 0.0032 0.0079 0.0075
Onchocerca volvulus 0.0116 0.0516 0.0498
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0079 0.0138
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0034 0.003
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0093 0.0398 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0018 0.0004 0.0007
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0034 0.003
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0032 0.0079 0.0075
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0191 0.091 0.0917
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0078 0.0074
Trypanosoma brucei glycerolphosphate mutase, putative 0.0032 0.0079 0.0075
Schistosoma mansoni phosphoglycerate mutase 0.0032 0.0079 0.0075
Loa Loa (eye worm) thymidylate synthase 0.008 0.0331 0.0327
Brugia malayi Trypsin-like protease protein 5 0.0191 0.091 0.0917
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0078 0.1379
Toxoplasma gondii phosphoglycerate mutase family protein 0.0032 0.0079 0.1215
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.003 0.0026
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.028 0.0276
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0045 0.0142 0.0124
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0101 0.0132
Trichomonas vaginalis methionyl-tRNA synthetase, putative 0.0025 0.0042 0.0095
Trypanosoma brucei glutaminyl cyclase, putative 0.0023 0.0029 0.0025
Onchocerca volvulus 0.0113 0.0502 0.0485
Loa Loa (eye worm) hypothetical protein 0.007 0.0278 0.0274
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0018 0.0004 0.0007
Brugia malayi Guanylyl cyclase protein 23 0.0026 0.0044 0.004
Mycobacterium tuberculosis Probable reductase 0.0134 0.0609 0.1065
Brugia malayi Muscle positioning protein 4 0.0116 0.0516 0.0518
Onchocerca volvulus 0.0024 0.0034 0.0015
Brugia malayi hypothetical protein 0.0026 0.0044 0.004
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0208 0.0997 0.1005
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0032 0.0079 0.0225
Schistosoma mansoni cell polarity protein 0.0116 0.0516 0.0512
Brugia malayi methionyl-tRNA synthetase 0.0025 0.0042 0.0038
Trypanosoma brucei 6-phosphofructo-2-kinase 2 0.1891 0.983 0.983
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0032 0.0028
Brugia malayi PXA domain containing protein 0.0023 0.003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.0101 0.0165
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0023 0.0029 0.0025
Echinococcus granulosus phosphoglycerate mutase 0.0032 0.0079 0.0075
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0034 0.003
Echinococcus granulosus phosphoglycerate mutase 0.0032 0.0079 0.0075
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0034 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0026 0.0044 0.004
Echinococcus granulosus microtubule associated protein 2 0.1544 0.8006 0.8006
Mycobacterium ulcerans phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0103 0.0451 0.0762
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.007 0.0278 0.0274
Mycobacterium leprae Probable cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.1107 0.5716 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0046
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0015
Echinococcus granulosus endoplasmic reticulum metallopeptidase 1 0.0023 0.0029 0.0025
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.028 0.0276
Trypanosoma cruzi trypanothione reductase, putative 0.0059 0.0215 0.0211
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.0235 0.1139 0.1135
Echinococcus granulosus protein jagged 2 0.0116 0.0516 0.0512
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0122 0.0118
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0034 0.003
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Onchocerca volvulus 0.0071 0.028 0.0262
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0026 0.0044 0.004
Schistosoma mansoni glutaminyl cyclase (M28 family) 0.0023 0.0029 0.0025
Echinococcus multilocularis fibrillin 1 0.0093 0.0398 0.0394
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.002 0.0015 0.0102
Echinococcus granulosus receptor type guanylyl cyclase 0.0026 0.0044 0.004
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Echinococcus granulosus glutamate receptor 2 0.0026 0.0044 0.004
Toxoplasma gondii LsmAD domain-containing protein 0.0019 0.001 0.009
Echinococcus granulosus phosphoglycerate mutase 0.0032 0.0079 0.0075
Echinococcus multilocularis protein jagged 2 0.0116 0.0516 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0109 0.0332
Onchocerca volvulus 0.0026 0.0044 0.0025
Leishmania major hypothetical protein, conserved 0.0023 0.0029 0.0025
Toxoplasma gondii phosphoglycerate mutase family protein 0.0032 0.0079 0.1215
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0191 0.091 0.0906
Echinococcus granulosus neuropeptide receptor A26 0.0515 0.261 0.2606
Echinococcus multilocularis microtubule associated protein 2 0.1544 0.8006 0.8006
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0394
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus multilocularis glutamate receptor 2 0.0026 0.0044 0.004
Mycobacterium ulcerans hypothetical protein 0.0032 0.0079 0.0127
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0148 0.0687 0.1202
Schistosoma mansoni coup transcription factor 0.0024 0.0034 0.003
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0018 0.0004 0.0007
Mycobacterium ulcerans phosphoglyceromutase 0.0032 0.0079 0.0127
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0034 0.003
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0034 0.003
Schistosoma mansoni hypothetical protein 0.029 0.1428 0.1424
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0042 0.0038
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0079 0.0138
Brugia malayi nicalin 0.0023 0.0029 0.0025
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0025 0.0042 0.003
Loa Loa (eye worm) hypothetical protein 0.0191 0.091 0.0906
Loa Loa (eye worm) hypothetical protein 0.1902 0.9886 0.9886
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.001 0.0006
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.002 0.0015 0.0172
Schistosoma mansoni inositol monophosphatase 0.0041 0.0122 0.0118
Loa Loa (eye worm) RGC/RGC protein kinase 0.0026 0.0044 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0034 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0042 0.0038
Leishmania major trypanothione reductase 0.0059 0.0215 0.0211
Trypanosoma cruzi glycerolphosphate mutase, putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0297 0.1466 0.1462
Loa Loa (eye worm) glutamate receptor 0.0233 0.1132 0.1129
Loa Loa (eye worm) thioredoxin reductase 0.0059 0.0215 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0034 0.003
Schistosoma mansoni eyes absent homolog 0.01 0.0433 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0034 0.003
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0032 0.0079 0.0075
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.1135 0.5864 1
Brugia malayi Trypsin family protein 0.0191 0.091 0.0917
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Mycobacterium tuberculosis Conserved protein 0.0032 0.0079 0.0138
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.003 0.0026
Schistosoma mansoni phosphoglycerate mutase 0.0032 0.0079 0.0075
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0034 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1902 0.9886 0.9886
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0034 0.003
Brugia malayi hypothetical protein 0.0023 0.003 0.0026
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0032 0.0079 0.0225
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Trypanosoma cruzi tyrosyl or methionyl-tRNA synthetase, putative 0.0025 0.0042 0.0038
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.003 0.0026
Brugia malayi Calcium binding EGF domain containing protein 0.0116 0.0516 0.0518
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0018 0.0004 0.0007
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Brugia malayi Trypsin family protein 0.0191 0.091 0.0917
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.002 0.0015 0.0011
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0101 0.0097
Onchocerca volvulus 0.1711 0.8884 0.8882
Mycobacterium leprae probable isochorismate synthase EntC 0.0032 0.0079 0.0138
Entamoeba histolytica hypothetical protein 0.0025 0.0042 0.003
Brugia malayi jmjC domain containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) serotonin transporter b 0.0021 0.0019 0.0015
Onchocerca volvulus Putative cubilin 0.0116 0.0516 0.0498
Brugia malayi Delta serrate ligand family protein 0.0116 0.0516 0.0518
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.003 0.0026
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0018 0.0004 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0018 0.0004 0.0007
Trypanosoma cruzi glutaminyl cyclase, putative 0.0023 0.0029 0.0025
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0148 0.0687 0.1202
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Mycobacterium leprae Conserved hypothetical protein 0.0018 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0113 0.0502 0.0498
Brugia malayi Calcium binding EGF domain containing protein 0.0116 0.0516 0.0518
Loa Loa (eye worm) hypothetical protein 0.1924 1 1
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0026 0.0044 0.004
Toxoplasma gondii phosphoglycerate mutase family protein 0.0032 0.0079 0.1215
Leishmania major tyrosyl-tRNA synthetase, putative 0.0033 0.0081 0.0076
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0034 0.003
Mycobacterium ulcerans lipoprotein aminopeptidase LpqL 0.0031 0.0073 0.0118
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0122 0.0118
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0032 0.0079 0.0075
Chlamydia trachomatis phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0039 0.0114 1
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0191 0.091 0.0906
Mycobacterium leprae Possible phosphoglycerate mutase 0.0032 0.0079 0.0138
Mycobacterium ulcerans cysteinyl-tRNA synthetase 0.1107 0.5716 0.9747
Echinococcus granulosus expressed protein 0.0451 0.2273 0.2269
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Echinococcus multilocularis thioredoxin glutathione reductase 0.0059 0.0215 0.0211
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.003 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0034 0.003
Mycobacterium tuberculosis Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) 0.0032 0.0079 0.0138
Echinococcus granulosus phd:f box containing protein 0.0032 0.0078 0.0074
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0032 0.0028
Onchocerca volvulus 0.0026 0.0044 0.0025
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0078 0.0074
Mycobacterium ulcerans acid phosphatase 0.0032 0.0079 0.0127
Mycobacterium ulcerans phosphohistidine phosphatase SixA 0.0032 0.0079 0.0127
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0037 0.0101 0.0097
Plasmodium falciparum thioredoxin reductase 0.0059 0.0215 0.4174
Echinococcus multilocularis aminoacyl tRNA synthase complex interacting 0.0025 0.0042 0.0038
Echinococcus multilocularis tyrosyl tRNA synthetase 0.0058 0.0214 0.021
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0032 0.0079 0.0075
Brugia malayi Fibulin-1 precursor 0.0093 0.0398 0.0399
Brugia malayi GCC2 and GCC3 family protein 0.0116 0.0516 0.0518
Brugia malayi Latrophilin receptor protein 2 0.0027 0.005 0.0046
Mycobacterium ulcerans phosphoglycerate mutase 0.0032 0.0079 0.0127
Plasmodium vivax methionine-tRNA ligase, putative 0.0025 0.0042 0.0651
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.008 0.0331 0.0578
Echinococcus multilocularis serine:threonine protein phosphatase PGAM5 0.0032 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0191 0.091 0.0906
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0034 0.003
Brugia malayi Trypsin family protein 0.1902 0.9886 1
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.0618 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Toxoplasma gondii exonuclease III APE 0.0037 0.0101 0.1585
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) 0.0032 0.0079 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0078 0.0074
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0036 0.0097 0.0093
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0134 0.0609 0.1065
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0022 0.0024 0.002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.028 0.0276
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0025
Mycobacterium tuberculosis Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) 0.0032 0.0079 0.0138
Mycobacterium tuberculosis Possible hydrolase MutT1 0.0032 0.0079 0.0138
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0122 0.0201
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0034 0.003
Wolbachia endosymbiont of Brugia malayi phenylalanyl-tRNA synthetase subunit beta 0.0025 0.0042 0.062
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Schistosoma mansoni 6-phosphofructokinase 0.1924 1 1
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0033 0.0081 0.0076
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0113 0.0502 0.0498
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0078 0.0074
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.003 0.0026
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative 0.0032 0.0079 0.0075
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0071 0.028 0.0276
Loa Loa (eye worm) hypothetical protein 0.0058 0.0214 0.021
Trypanosoma brucei tyrosyl/methionyl-tRNA synthetase, putative 0.0025 0.0042 0.0038
Echinococcus multilocularis serotonin transporter 0.0021 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0074
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0032 0.0079 0.0094
Onchocerca volvulus 0.0562 0.2857 0.2843
Brugia malayi ecdysteroid receptor 0.0024 0.0034 0.003
Echinococcus granulosus phosphoglycerate mutase 0.0032 0.0079 0.0075
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0068 0.0266 0.0262
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0021 0.0019 0.0015
Mycobacterium tuberculosis Conserved protein 0.0032 0.0079 0.0138
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0034 0.003
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0078 0.0074
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0022 0.0024 0.002
Schistosoma mansoni hypothetical protein 0.0021 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.1103 0.5694 0.5692
Brugia malayi Thioredoxin reductase 0.0059 0.0215 0.0214
Schistosoma mansoni jumonji domain containing protein 0.0121 0.0543 0.0539
Entamoeba histolytica phosphoglycerate mutase family protein. putative 0.0032 0.0079 0.0094
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1924 1 1
Loa Loa (eye worm) RGS-3 protein 0.0023 0.003 0.0026
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.002 0.0015 0.0102
Mycobacterium ulcerans lipoprotein LpqD 0.0032 0.0079 0.0127
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0027 0.005 0.0046
Chlamydia trachomatis phenylalanine--tRNA ligase subunit beta 0.0025 0.0042 0.2711
Toxoplasma gondii calcium binding egf domain-containing protein 0.0093 0.0398 0.6425
Loa Loa (eye worm) hypothetical protein 0.1902 0.9886 0.9886
Mycobacterium ulcerans hypothetical protein 0.0032 0.0079 0.0127
Schistosoma mansoni microtubule-associated protein tau 0.1544 0.8006 0.8006
Leishmania major dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Echinococcus granulosus transmembrane protease serine 3 0.0191 0.091 0.0906
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0075
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0134 0.0609 0.1065
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0097 0.0093
Brugia malayi metabotropic glutamate receptor type 2 0.0134 0.0611 0.0614
Schistosoma mansoni ap endonuclease 0.0037 0.0101 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Echinococcus granulosus Mastin 0.0191 0.091 0.0906
Echinococcus multilocularis glutamate receptor 2 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Loa Loa (eye worm) hypothetical protein 0.0085 0.0355 0.0351
Echinococcus granulosus protein jagged 1 0.0116 0.0516 0.0512
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0087 0.0363 0.0359
Schistosoma mansoni hypothetical protein 0.0027 0.005 0.0046
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Brugia malayi hypothetical protein 0.01 0.0433 0.0434
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Leishmania major hypothetical protein, conserved 0.0032 0.0079 0.0075
Treponema pallidum undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 0.0024 0.0033 0.1881
Brugia malayi Receptor family ligand binding region containing protein 0.0026 0.0044 0.004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.002 0.0015 0.0102
Loa Loa (eye worm) glutaminase 0.0139 0.0635 0.0631
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0101 0.0166
Mycobacterium tuberculosis Probable dehydrogenase 0.0134 0.0609 0.1065
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0034 0.003
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0093 0.0398 0.0394
Brugia malayi Receptor family ligand binding region containing protein 0.007 0.0278 0.0277
Echinococcus granulosus GPCR family 2 0.0027 0.005 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0034 0.003
Toxoplasma gondii phosphoglycerate mutase 0.0032 0.0079 0.1215
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0071 0.028 0.0276
Entamoeba histolytica hypothetical protein 0.0023 0.003 0.001
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0006 0.0002
Echinococcus granulosus laminin 0.0093 0.0398 0.0394
Trypanosoma cruzi phosphoglycerate mutase family member 5, putative 0.0032 0.0079 0.0075
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Plasmodium falciparum cysteine repeat modular protein 1 0.0113 0.0502 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.003 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0101 0.0097
Mycobacterium ulcerans phenylalanyl-tRNA synthetase subunit beta 0.0025 0.0042 0.0064
Mycobacterium tuberculosis PE-PGRS family protein PE_PGRS11 0.0032 0.0079 0.0138
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0034 0.003
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Schistosoma mansoni hypothetical protein 0.0191 0.091 0.0906
Schistosoma mansoni Fxna peptidase (M28 family) 0.0023 0.0029 0.0025
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.003 0.0026
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0101 0.0097
Onchocerca volvulus 0.0191 0.091 0.0893
Loa Loa (eye worm) leucyl aminopeptidase 0.0023 0.0029 0.0025
Brugia malayi nuclear receptor NHR-88 0.0024 0.0034 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0618 0.1047
Onchocerca volvulus 0.0191 0.091 0.0893
Schistosoma mansoni slit 0.0116 0.0516 0.0512
Brugia malayi Metabotropic glutamate receptor precursor. 0.0233 0.1132 0.1142
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.0101 0.0097
Echinococcus granulosus tyrosine kinase 0.0026 0.0044 0.004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.0078 0.0074
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0034 0.003
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1891 0.983 0.983
Brugia malayi notch-like transmembrane receptor 0.0116 0.0516 0.0518
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0037 0.0101 0.0098
Schistosoma mansoni regulator of G protein signaling 0.0023 0.003 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0034 0.003
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0026 0.0044 0.004
Plasmodium vivax phosphoglycerate mutase, putative 0.0032 0.0079 0.14
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.0618 0.0614
Schistosoma mansoni hypothetical protein 0.0022 0.0024 0.002
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0093 0.0398 0.0399
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.003 0.0026
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0101 0.0148
Brugia malayi Pre-SET motif family protein 0.0494 0.2499 0.2525
Onchocerca volvulus 0.0032 0.0079 0.006
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.0006
Brugia malayi phosphoglycerate mutase family protein 0.0032 0.0079 0.0075
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0078 0.1198
Leishmania major phosphoglycerate mutase, putative 0.0032 0.0079 0.0075
Schistosoma mansoni ap endonuclease 0.0037 0.0101 0.0097
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0122 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Entamoeba histolytica phosphoglycerate mutase family protein, putative 0.0032 0.0079 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Loa Loa (eye worm) glutamate receptor 0.0108 0.0475 0.0472
Echinococcus granulosus neuropeptide s receptor 0.0515 0.261 0.2606
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.002 0.0015 0.0011
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0021 0.0019 0.0015
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Schistosoma mansoni egf-like domain protein 0.0093 0.0398 0.0394
Leishmania major hypothetical protein, conserved 0.0032 0.0079 0.0075
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.003 0.0026
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0121 0.0543 0.0539
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0034 0.003
Echinococcus multilocularis nmda type glutamate receptor 0.0026 0.0044 0.004
Echinococcus granulosus nmda type glutamate receptor 0.0026 0.0044 0.004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.0618 0.1047
Loa Loa (eye worm) hypothetical protein 0.01 0.0433 0.0429
Loa Loa (eye worm) TK/ROR protein kinase 0.0113 0.0502 0.0498
Loa Loa (eye worm) hypothetical protein 0.0019 0.0007 0.0003
Echinococcus granulosus aminoacyl tRNA synthase complex interacting 0.0025 0.0042 0.0038
Giardia lamblia Methionyl-tRNA synthetase 0.0025 0.0042 0.0046
Onchocerca volvulus 0.0191 0.091 0.0893
Chlamydia trachomatis UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 0.0024 0.0033 0.1881
Toxoplasma gondii NADPH-glutathione reductase 0.002 0.0015 0.0172
Entamoeba histolytica hypothetical protein 0.0023 0.003 0.001
Echinococcus granulosus serotonin transporter 0.0021 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0032 0.0079 0.0075
Onchocerca volvulus 0.1902 0.9886 0.9886
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0034 0.003
Echinococcus granulosus Tolloid protein 1 0.0093 0.0398 0.0394
Mycobacterium tuberculosis Conserved hypothetical protein 0.0032 0.0079 0.0138
Echinococcus granulosus fibropellin Ia 0.0116 0.0516 0.0512
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0032 0.006
Brugia malayi jmjC domain containing protein 0.0121 0.0543 0.0546
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.003 0.0026
Brugia malayi glutaminase DH11.1 0.0139 0.0635 0.0638
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Trichomonas vaginalis glutaminase, putative 0.0139 0.0635 0.2182
Schistosoma mansoni nicalin (M28 family) 0.0023 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0001
Brugia malayi leucyl aminopeptidase 0.0023 0.0029 0.0025
Schistosoma mansoni axis inhibition protein axin 0.0023 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0101 0.8693
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.002 0.0015 0.0011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0101 0.0177
Echinococcus multilocularis neurogenic locus notch protein 0.0116 0.0516 0.0512
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.008 0.0331 0.0327
Brugia malayi Calcium binding EGF domain containing protein 0.0093 0.0398 0.0399
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0074
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0018 0.0004 0.0007
Leishmania major hypothetical protein, conserved 0.0113 0.0502 0.0498
Schistosoma mansoni methionyl-tRNA synthetase 0.0025 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein 0.0821 0.4214 0.4212
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.008 0.0331 0.0578
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0034 0.003
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Loa Loa (eye worm) trypsin family protein 0.0191 0.091 0.0906
Echinococcus multilocularis transmembrane protease serine 3 0.0191 0.091 0.0906
Leishmania major acetoin dehydrogenase e3 component-like protein 0.002 0.0015 0.0011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0034 0.003
Mycobacterium tuberculosis Hypothetical protein 0.0038 0.0109 0.0191
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0022 0.0024 0.002
Mycobacterium leprae POSSIBLE HYDROLASE MUTT1 0.0032 0.0079 0.0138
Trichomonas vaginalis isoleucyl, leucyl, tyrosyl, valyl and methionyl-tRNA synthetases, putative 0.0033 0.0081 0.0232
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0038 0.0109 0.0105
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.003 0.0026
Mycobacterium tuberculosis Probable phenylalanyl-tRNA synthetase, beta chain PheT 0.0025 0.0042 0.0073
Leishmania major phosphoglycerate mutase protein, putative 0.0032 0.0079 0.0075
Brugia malayi Calcitonin receptor-like protein seb-1 0.0085 0.0355 0.0355
Trypanosoma cruzi trypanothione reductase, putative 0.002 0.0015 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0023 0.003 0.0026
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.0078 0.0074
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.003 0.0026
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.0618 0.0614
Echinococcus multilocularis phosphoglycerate mutase 0.0032 0.0079 0.0075
Echinococcus multilocularis neuropeptide receptor A26 0.0515 0.261 0.2606
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0078 0.0074
Plasmodium falciparum glutathione reductase 0.002 0.0015 0.0102
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0026 0.0044 0.004
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0078 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0034 0.003
Schistosoma mansoni tyrosine kinase 0.0026 0.0044 0.004
Plasmodium vivax phosphoglucomutase-2, putative 0.0032 0.0079 0.14
Brugia malayi Cytochrome P450 family protein 0.0037 0.0101 0.0098
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0018 0.0004 0.0007
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0018 0.0004 0.0007
Toxoplasma gondii phosphoglycerate mutase PGMII 0.0032 0.0079 0.1215
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0122 0.0118
Schistosoma mansoni hypothetical protein 0.0045 0.0142 0.0138
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0101 0.0097
Echinococcus multilocularis lysine specific demethylase 5A 0.0121 0.0543 0.0539
Loa Loa (eye worm) hypothetical protein 0.0032 0.0078 0.0074
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0116 0.0516 0.0512
Leishmania major tyrosyl or methionyl-tRNA synthetase-like protein 0.0025 0.0042 0.0038
Echinococcus granulosus glutaminyl peptide cyclotransferase 0.0023 0.0029 0.0025
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0543 0.0539
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0297 0.1466 0.1462
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0022 0.0024 0.002
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Onchocerca volvulus 0.1924 1 1
Entamoeba histolytica hypothetical protein 0.0023 0.003 0.001
Echinococcus granulosus protein jagged 1 0.0116 0.0516 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.003 0.0053
Trypanosoma brucei 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1924 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0042 0.0095
Brugia malayi Inositol-1 0.0041 0.0122 0.0119
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0034 0.003
Mycobacterium ulcerans hydrolase MutT1 0.0032 0.0079 0.0127
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0024 0.0034 0.0015
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0022 0.0024 0.002
Toxoplasma gondii tRNA synthetases class I family protein 0.0033 0.0081 0.1246
Echinococcus granulosus delta-like protein 1 0.0116 0.0516 0.0512
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.003 0.0026
Trypanosoma brucei tyrosyl-tRNA synthetase, putative 0.0025 0.0042 0.0038
Trichomonas vaginalis phosphoglycerate mutase, putative 0.0032 0.0079 0.0225
Echinococcus multilocularis tissue type plasminogen activator 0.0113 0.0502 0.0498
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0502 0.0498
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0191 0.091 0.0906
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0034 0.003
Echinococcus granulosus axis inhibition protein axin 0.0023 0.003 0.0026
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0494 0.2499 0.2496
Brugia malayi Protein kinase domain containing protein 0.0113 0.0502 0.0504
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Schistosoma mansoni metabotropic glutamate receptor 0.0134 0.0611 0.0607
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Mycobacterium ulcerans thymidylate synthase 0.008 0.0331 0.0557
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0034 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0078 0.0074
Toxoplasma gondii EGF family domain-containing protein 0.0116 0.0516 0.8341
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Onchocerca volvulus Protein ultraspiracle homolog 0.0024 0.0034 0.0015
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0023 0.0029 0.0025
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.002 0.0015 0.0011
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0116 0.0516 0.0518
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Schistosoma mansoni metabotropic glutamate receptor 0.0189 0.0898 0.0895
Schistosoma mansoni hypothetical protein 0.0027 0.005 0.0046
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.002 0.0015 0.0011
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0101 0.0097
Brugia malayi jmjC domain containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.003 0.0026
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0148 0.0687 0.1202
Toxoplasma gondii hypothetical protein 0.0023 0.0029 0.0404
Echinococcus multilocularis Mastin 0.0191 0.091 0.0906
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0079 0.0225
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0191 0.091 0.0906
Brugia malayi jmjC domain containing protein 0.0121 0.0543 0.0546
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0101 0.0097
Mycobacterium leprae PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) 0.0032 0.0079 0.0138
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0018 0.0004 0.0007
Brugia malayi steroid hormone receptor 0.0024 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus granulosus atrial natriuretic peptide receptor 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0034 0.003
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0101 0.1861
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0022 0.0024 0.002
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0116 0.0516 0.0498
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.002 0.0015 0.0018
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.003 0.0026
Echinococcus multilocularis laminin 0.0093 0.0398 0.0394
Brugia malayi EGF-like domain containing protein 0.0116 0.0516 0.0518
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0034 0.003
Schistosoma mansoni glutaminyl-peptide cyclotransferase-related 0.0023 0.0029 0.0025
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.0618 0.108
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0078 0.1198
Loa Loa (eye worm) solute carrier family 6 member 4 0.0021 0.0019 0.0015
Echinococcus granulosus thymidylate synthase 0.008 0.0331 0.0327
Trypanosoma cruzi 6-phosphofructo-2-kinase 1 0.1891 0.983 0.983
Schistosoma mansoni regulator of G protein signaling 0.0023 0.003 0.0026
Echinococcus multilocularis receptor type guanylyl cyclase 0.0026 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0024 0.0033
Onchocerca volvulus Protein UBASH3A homolog 0.0032 0.0079 0.006
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0036 0.0097 0.0093
Schistosoma mansoni inositol monophosphatase 0.0041 0.0122 0.0118
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.002 0.0015 0.0011
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0099 0.0174
Loa Loa (eye worm) hypothetical protein 0.0026 0.0044 0.004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0059 0.0215 0.0377
Leishmania major cytochrome p450-like protein 0.0037 0.0101 0.0097
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0034 0.003
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0087 0.0363 0.0359
Entamoeba histolytica hypothetical protein 0.0025 0.0042 0.003
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0191 0.091 0.0906
Loa Loa (eye worm) hypothetical protein 0.0191 0.091 0.0906
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0101 0.0097
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0018 0.0004 0.0007
Trypanosoma brucei cytochrome P450, putative 0.0037 0.0101 0.0097
Brugia malayi Peptidase family M28 containing protein 0.0023 0.0029 0.0025
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.002 0.0015 0.0011
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0087 0.0363 0.7161
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.002 0.0015 0.0102
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Toxoplasma gondii tRNA binding domain-containing protein 0.0025 0.0042 0.0613
Schistosoma mansoni axis inhibition protein axin 0.0023 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Onchocerca volvulus Slit protein homolog 0.0116 0.0516 0.0498
Brugia malayi latrophilin 2 splice variant baaae 0.0058 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0045 0.0142 0.0138
Echinococcus multilocularis glycoprotein Antigen 5 0.0191 0.091 0.0906
Schistosoma mansoni septate junction protein 0.0116 0.0516 0.0512
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0027 0.005 0.0046
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.0821 0.4214 0.4212
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Onchocerca volvulus 0.0116 0.0516 0.0498
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0101 0.1861
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.021 0.0206
Loa Loa (eye worm) notch protein 0.0116 0.0516 0.0512
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0034 0.003
Mycobacterium ulcerans hypothetical protein 0.1135 0.5864 1
Onchocerca volvulus 0.0023 0.0029 0.001
Leishmania major glycerolphosphate mutase, putative 0.0032 0.0079 0.0075
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.002 0.0015 0.0018
Brugia malayi Cytochrome P450 family protein 0.0058 0.021 0.0208
Schistosoma mansoni tyrosine kinase 0.0026 0.0044 0.004
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0034 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0101 0.0305
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.003 0.0026
Loa Loa (eye worm) glutaminase 2 0.0139 0.0635 0.0631
Loa Loa (eye worm) glutathione reductase 0.0059 0.0215 0.0211
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase 0.0024 0.0033 0.043
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0018 0.0004 0.0007
Schistosoma mansoni glutaminase 0.0139 0.0635 0.0631
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.003 0.0026
Leishmania major hypothetical protein, conserved 0.0032 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.1891 0.983 0.983
Trypanosoma cruzi phosphoglycerate mutase protein, putative 0.0032 0.0079 0.0075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0122 0.0118
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0093 0.0398 0.0394
Trypanosoma cruzi 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1924 1 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0021 0.0019 0.0402
Schistosoma mansoni notch 0.0116 0.0516 0.0512
Leishmania major glutaminyl cyclase, putative 0.0023 0.0029 0.0025
Mycobacterium ulcerans phosphoglycerate mutase 0.0032 0.0079 0.0127
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0134 0.0609 0.1065
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0394
Brugia malayi hypothetical protein 0.0191 0.091 0.0917
Schistosoma mansoni protein kinase 0.0026 0.0044 0.004
Trypanosoma brucei phosphoglycerate mutase, putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0101 0.0097
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0018 0.0004 0.0007
Trypanosoma brucei Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Leishmania major hypothetical protein, conserved 0.0032 0.0079 0.0075
Toxoplasma gondii phosphoglycerate mutase family protein 0.0032 0.0079 0.1215
Brugia malayi Trypsin family protein 0.0191 0.091 0.0917
Entamoeba histolytica hypothetical protein 0.0026 0.0044 0.0034
Leishmania major hypothetical protein 0.0025 0.0042 0.0038
Trypanosoma brucei phosphoglycerate mutase protein, putative 0.0032 0.0079 0.0075
Brugia malayi Cadherin domain containing protein 0.0116 0.0516 0.0518
Giardia lamblia High cysteine protein 0.0116 0.0516 0.0857
Loa Loa (eye worm) hypothetical protein 0.0093 0.0398 0.0394
Trypanosoma brucei PAB1-binding protein , putative 0.0019 0.001 0.0006
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0017 0.0142
Echinococcus granulosus bloom syndrome protein 0.0024 0.0032 0.0028
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0022 0.0024 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0042 0.0095
Loa Loa (eye worm) phosphoglycerate mutase 0.0032 0.0079 0.0075
Giardia lamblia Hypothetical protein 0.1135 0.5864 1
Echinococcus granulosus axis inhibition protein axin 0.0023 0.003 0.0026
Brugia malayi hypothetical protein 0.0019 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Echinococcus multilocularis neurogenic locus notch protein 0.0116 0.0516 0.0512
Onchocerca volvulus 0.008 0.0331 0.0312
Onchocerca volvulus 0.0116 0.0516 0.0498
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0022 0.0024 0.002
Giardia lamblia Tyrosyl-tRNA synthetase 0.0033 0.0081 0.0113
Onchocerca volvulus Bile acid receptor homolog 0.0024 0.0034 0.0015
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.003
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0226 0.1095 0.1091
Mycobacterium ulcerans flavoprotein disulfide reductase 0.002 0.0015 0.0018
Echinococcus granulosus thioredoxin glutathione reductase 0.0059 0.0215 0.0211
Brugia malayi PXA domain containing protein 0.0023 0.003 0.0026
Echinococcus multilocularis expressed protein 0.0451 0.2273 0.2269
Echinococcus granulosus glycoprotein Antigen 5 0.0191 0.091 0.0906
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0122 0.0118
Echinococcus granulosus metabotropic glutamate receptor 5 0.0297 0.1466 0.1462
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0134 0.0609 0.1065
Echinococcus granulosus neurogenic locus notch protein 0.0116 0.0516 0.0512
Brugia malayi jmjC domain containing protein 0.0032 0.0078 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0034 0.003
Trypanosoma cruzi Histidine phosphatase superfamily (branch 1), putative 0.0032 0.0079 0.0075
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0026 0.0044 0.004
Echinococcus granulosus slit 2 protein 0.0116 0.0516 0.0512
Onchocerca volvulus Protein UBASH3A homolog 0.0032 0.0079 0.006
Echinococcus multilocularis Tolloid protein 1 0.0093 0.0398 0.0394
Mycobacterium tuberculosis Probable oxidoreductase 0.0148 0.0687 0.1202
Echinococcus multilocularis glutaminyl peptide cyclotransferase 0.0023 0.0029 0.0025
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0101 0.1989
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.003 0.0026
Echinococcus granulosus serine:threonine protein phosphatase PGAM5 0.0032 0.0079 0.0075
Plasmodium vivax tyrosine--tRNA ligase, putative 0.0033 0.0081 0.1439
Giardia lamblia Hypothetical protein 0.1135 0.5864 1
Trypanosoma brucei trypanothione reductase 0.0059 0.0215 0.0211
Leishmania major hypothetical protein, conserved 0.0025 0.0042 0.0038
Toxoplasma gondii kringle domain-containing protein 0.0113 0.0502 0.8123
Wolbachia endosymbiont of Brugia malayi phospho-N-acetylmuramoyl-pentapeptide-transferase 0.0103 0.0451 1
Treponema pallidum methionyl-tRNA synthetase 0.0025 0.0042 0.2711
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Mycobacterium leprae conserved hypothetical protein 0.0032 0.0079 0.0138
Onchocerca volvulus 0.0191 0.091 0.0893
Plasmodium falciparum thioredoxin reductase 0.002 0.0015 0.0102
Echinococcus multilocularis endoplasmic reticulum metallopeptidase 1 0.0023 0.0029 0.0025
Schistosoma mansoni hypothetical protein 0.0191 0.091 0.0906
Trichomonas vaginalis rotamase, putative 0.0036 0.0097 0.0289
Leishmania major 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative 0.1924 1 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0018 0.0004 0.0007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0121 0.0543 0.0539
Loa Loa (eye worm) hypothetical protein 0.0191 0.091 0.0906
Mycobacterium leprae Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX 0.0103 0.0451 0.0788
Mycobacterium ulcerans undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 0.0024 0.0033 0.005
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0122 0.1918
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0113 0.0502 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0034 0.003
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0071 0.028 0.4495
Loa Loa (eye worm) hypothetical protein 0.0023 0.003 0.0026
Echinococcus granulosus enteropeptidase 0.0191 0.091 0.0906
Trypanosoma brucei Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative 0.0032 0.0079 0.0075
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0025 0.0042 0.0038
Schistosoma mansoni cercarial elastase (S01 family) 0.0191 0.091 0.0906
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0101 0.0097
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.003 0.0026
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0078 0.0074
Mycobacterium leprae putative cytochrome p450 0.0018 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0116 0.0516 0.0512
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0101 0.0097
Echinococcus granulosus tyrosyl tRNA synthetase 0.0058 0.0214 0.021
Onchocerca volvulus 0.0032 0.0079 0.006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0085 0.0355 0.0355
Plasmodium falciparum tyrosine--tRNA ligase 0.0033 0.0081 0.1439
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0087 0.0363 0.5842
Schistosoma mansoni hypothetical protein 0.0032 0.0079 0.0075
Plasmodium falciparum glutathione reductase 0.0059 0.0215 0.4174
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0026 0.0044 0.0025
Leishmania major phosphoglycerate mutase family member 5, putative 0.0032 0.0079 0.0075
Brugia malayi Cadherin domain containing protein 0.0116 0.0516 0.0518
Leishmania major hypothetical protein, conserved 0.0019 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0116 0.0516 0.0512
Echinococcus granulosus neurogenic locus notch protein 0.0116 0.0516 0.0512
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0122 0.0377
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0018 0.0004 0.0007
Leishmania major fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein 0.0032 0.0079 0.0075
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.002 0.0015 0.0011
Loa Loa (eye worm) hypothetical protein 0.0071 0.028 0.0276
Mycobacterium tuberculosis Cysteine:1D-myo-inosityl 2-amino-2-deoxy--D-glucopyranoside ligase MshC 0.1107 0.5716 1
Echinococcus multilocularis enteropeptidase 0.0191 0.091 0.0906
Echinococcus multilocularis geminin 0.029 0.1428 0.1424
Echinococcus granulosus neural cadherin 0.0116 0.0516 0.0512
Echinococcus multilocularis neural cadherin 0.0116 0.0516 0.0512
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0036 0.0097 0.0125

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.