TDR Targets

Basic information

Technical information

TDR Targets ID: 1798063
Name: N-[3-(1H-indol-3-yl)propyl]acetamide
MW: 216.279 | Formula: C13H16N2O
H donors: 2 H acceptors: 1 LogP: 1.98 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: CC(=O)NCCCc1c[nH]c2c1cccc2
InChi: 1S/C13H16N2O/c1-10(16)14-8-4-5-11-9-15-13-7-3-2-6-12(11)13/h2-3,6-7,9,15H,4-5,8H2,1H3,(H,14,16)
InChiKey: CSFBYQFLVJSVHA-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[3-(1H-indol-3-yl)propyl]ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.006	0.0136	1
Trypanosoma cruzi	6-phosphofructo-2-kinase 1	0.3511	0.9831	0.983
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Toxoplasma gondii	phosphoglycerate mutase PGMII	0.006	0.0136	0.396
Echinococcus multilocularis	cytoplasmic intermediate filament protein	0.0045	0.0093	0.0093
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Mycobacterium ulcerans	hypothetical protein	0.006	0.0136	0.0091
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.006	0.0136	1
Leishmania major	hypothetical protein, conserved	0.006	0.0136	0.0118
Loa Loa (eye worm)	hypothetical protein	0.006	0.0136	0.0136
Echinococcus granulosus	phosphoglycerate mutase	0.006	0.0136	0.0136
Trichomonas vaginalis	conserved hypothetical protein	0.006	0.0136	1
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0043	0.0088	0.0088
Onchocerca volvulus		0.006	0.0136	0.0136
Echinococcus granulosus	cytoplasmic intermediate filament protein	0.0045	0.0093	0.0093
Plasmodium falciparum	phosphoglucomutase-2	0.006	0.0136	1
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0093	0.0093
Leishmania major	hypothetical protein, conserved	0.006	0.0136	0.0118
Loa Loa (eye worm)	inositol-1	0.0042	0.0084	0.0084
Loa Loa (eye worm)	hypothetical protein	0.006	0.0136	0.0136
Loa Loa (eye worm)	hypothetical protein	0.2047	0.5719	0.5719
Loa Loa (eye worm)	jmjC domain-containing protein	0.0018	0.0018	0.0018
Brugia malayi	cytoplasmic intermediate filament protein	0.005	0.0107	0.1501
Echinococcus multilocularis	musashi	0.0093	0.0229	0.0229
Mycobacterium ulcerans	phosphoglycerate mutase	0.006	0.0136	0.0091
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.2108	0.5888	1
Schistosoma mansoni	survival motor neuron protein	0.0054	0.012	0.012
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0054	0.012	0.1672
Echinococcus multilocularis	lysine specific demethylase 6a	0.0018	0.0018	0.0018
Echinococcus multilocularis	microtubule associated protein 2	0.0777	0.2149	0.2149
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Echinococcus multilocularis	cpg binding protein	0.0069	0.0162	0.0162
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.1524	0.4248	0.4238
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0043	0.0088	0.0088
Mycobacterium tuberculosis	Conserved protein	0.006	0.0136	1
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0043	0.0088	0.007
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0072	0.017	0.017
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Plasmodium vivax	phosphoglucomutase-2, putative	0.006	0.0136	1
Mycobacterium tuberculosis	Conserved protein	0.006	0.0136	1
Echinococcus granulosus	lamin dm0	0.0093	0.0229	0.0229
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0043	0.0088	0.1237
Echinococcus granulosus	survival motor neuron protein 1	0.0266	0.0715	0.0715
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0043	0.0088	0.0088
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0043	0.0088	0.6237
Echinococcus granulosus	inositol monophosphatase 1	0.0042	0.0084	0.0084
Trypanosoma brucei	phosphoglycerate mutase, putative	0.006	0.0136	0.0118
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0016	0.0013	0.0013
Echinococcus granulosus	dnaJ subfamily B	0.0936	0.2595	0.2595
Onchocerca volvulus		0.0066	0.0152	0.0152
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.1524	0.4248	0.4238
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0255
Mycobacterium ulcerans	lipoprotein LpqD	0.006	0.0136	0.0091
Mycobacterium tuberculosis	Conserved hypothetical protein	0.006	0.0136	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0105	0.0262	0.0262
Echinococcus granulosus	lysine specific demethylase 5A	0.0072	0.017	0.017
Loa Loa (eye worm)	phosphoglycerate mutase	0.006	0.0136	0.0136
Mycobacterium ulcerans	hydrolase MutT1	0.006	0.0136	0.0091
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0016	0.0013	0.0013
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.3571	1	1
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0089	0.0089
Giardia lamblia	Hypothetical protein	0.2108	0.5888	1
Schistosoma mansoni	lamin	0.0093	0.0229	0.0229
Schistosoma mansoni	cpg binding protein	0.0069	0.0162	0.0162
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.006	0.0136	0.0118
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0016	0.0013	0.0013
Trypanosoma brucei	6-phosphofructo-2-kinase 2	0.3511	0.9831	0.983
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0042	0.0084	0.0066
Brugia malayi	Intermediate filament tail domain containing protein	0.0093	0.0229	0.3202
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.0093	0.0229	0.0229
Brugia malayi	CXXC zinc finger family protein	0.0066	0.0152	0.2121
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0088	0.6237
Mycobacterium tuberculosis	Probable conserved lipoprotein LpqD	0.006	0.0136	1
Trypanosoma cruzi	phosphoglycerate mutase family member 5, putative	0.006	0.0136	0.0118
Schistosoma mansoni	jumonji domain containing protein	0.0018	0.0018	0.0018
Onchocerca volvulus	Protein UBASH3A homolog	0.006	0.0136	0.0136
Echinococcus multilocularis	dnaJ subfamily B	0.0936	0.2595	0.2595
Loa Loa (eye worm)	hypothetical protein	0.3511	0.9831	0.9831
Schistosoma mansoni	microtubule-associated protein tau	0.0777	0.2149	0.2149
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.0042	0.0084	0.5
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein	0.1524	0.4248	0.4238
Trypanosoma brucei	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Toxoplasma gondii	phosphoglycerate mutase family protein	0.006	0.0136	0.396
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Echinococcus granulosus	cpg binding protein	0.0069	0.0162	0.0162
Onchocerca volvulus		0.0093	0.0229	0.0229
Loa Loa (eye worm)	hypothetical protein	0.006	0.0136	0.0136
Leishmania major	fructose-6-phosphate2-kinase/fructose-2,6-bisph os phatase-likeprotein	0.006	0.0136	0.0118
Echinococcus multilocularis	lamin	0.0093	0.0229	0.0229
Onchocerca volvulus		0.0054	0.012	0.012
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0105	0.0262	0.0262
Echinococcus multilocularis	6 phosphofructo 2 kinase:fructose 2	0.3571	1	1
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Leishmania major	hypothetical protein, unknown function	0.006	0.0136	0.0118
Schistosoma mansoni	phosphatidylserine receptor	0.0018	0.0018	0.0018
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0043	0.0088	0.007
Trypanosoma brucei	Serine/threonine-protein phosphatase PGAM5, mitochondrial, putative	0.006	0.0136	0.0118
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136
Echinococcus multilocularis	neuropeptide s receptor	0.052	0.1429	0.1429
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0105	0.0262	0.0262
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0042	0.0084	0.0066
Echinococcus multilocularis	serine:threonine protein phosphatase PGAM5	0.006	0.0136	0.0136
Echinococcus granulosus	microtubule associated protein 2	0.0777	0.2149	0.2149
Echinococcus granulosus	jumonji domain containing 1A	0.0018	0.0018	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0018	0.0018
Chlamydia trachomatis	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase	0.006	0.0136	0.5
Onchocerca volvulus		0.006	0.0136	0.0136
Echinococcus granulosus	phosphoglycerate mutase	0.006	0.0136	0.0136
Schistosoma mansoni	6-phosphofructokinase	0.3571	1	1
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0068	0.0159	0.0159
Schistosoma mansoni	cpg binding protein	0.0069	0.0162	0.0162
Echinococcus granulosus	JmjC domain containing protein 4	0.0018	0.0018	0.0018
Mycobacterium leprae	conserved hypothetical protein	0.006	0.0136	1
Leishmania major	phosphoglycerate mutase family member 5, putative	0.006	0.0136	0.0118
Trichomonas vaginalis	conserved hypothetical protein	0.006	0.0136	1
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.006	0.0136	1
Mycobacterium ulcerans	fructose-2,6-bisphosphatase GpmB	0.2108	0.5888	1
Plasmodium vivax	phosphoglycerate mutase, putative	0.006	0.0136	1
Mycobacterium ulcerans	phosphohistidine phosphatase SixA	0.006	0.0136	0.0091
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Brugia malayi	F/Y-rich N-terminus family protein	0.002	0.0023	0.0327
Echinococcus granulosus	phosphoglycerate mutase	0.006	0.0136	0.0136
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.006	0.0136	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0091	0.0224	0.0224
Loa Loa (eye worm)	hypothetical protein	0.3571	1	1
Loa Loa (eye worm)	histone methyltransferase	0.002	0.0024	0.0024
Mycobacterium leprae	Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase)	0.006	0.0136	1
Schistosoma mansoni	inositol monophosphatase	0.0042	0.0084	0.0084
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0124	0.0317	1
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.002	0.0024	0.0024
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0043	0.0088	0.0088
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0016	0.0013	0.0013
Echinococcus granulosus	neuropeptide s receptor	0.052	0.1429	0.1429
Toxoplasma gondii	phosphoglycerate mutase	0.006	0.0136	0.396
Schistosoma mansoni	hypothetical protein	0.0054	0.012	0.012
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.3571	1	1
Echinococcus granulosus	phosphoglycerate mutase	0.006	0.0136	0.0136
Trypanosoma cruzi	phosphoglycerate mutase protein, putative	0.006	0.0136	0.0118
Trypanosoma cruzi	6-phosphofructo-2-kinase 1	0.3511	0.9831	0.983
Brugia malayi	jmjC domain containing protein	0.0068	0.0159	0.2225
Echinococcus multilocularis	lamin dm0	0.0093	0.0229	0.0229
Echinococcus multilocularis	neuropeptide receptor A26	0.052	0.1429	0.1429
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0042	0.0084	0.0066
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.1524	0.4248	0.4238
Onchocerca volvulus	Protein UBASH3A homolog	0.006	0.0136	0.0136
Brugia malayi	Inositol-1	0.0042	0.0084	0.1172
Schistosoma mansoni	inositol monophosphatase	0.0042	0.0084	0.0084
Mycobacterium leprae	conserved hypothetical protein	0.006	0.0136	1
Mycobacterium leprae	probable isochorismate synthase EntC	0.006	0.0136	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0018	0.0018	0.0018
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0022	0.0029	0.0029
Onchocerca volvulus		0.0093	0.0229	0.0229
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136
Leishmania major	phosphoglycerate mutase, putative	0.006	0.0136	0.0118
Leishmania major	phosphoglycerate mutase protein, putative	0.006	0.0136	0.0118
Onchocerca volvulus	Protein UBASH3A homolog	0.006	0.0136	0.0136
Mycobacterium ulcerans	bifunctional RNase H/acid phosphatase	0.006	0.0136	0.0091
Trypanosoma cruzi	phosphoglycerate mutase, putative	0.006	0.0136	0.0118
Mycobacterium ulcerans	acid phosphatase	0.006	0.0136	0.0091
Echinococcus granulosus	neuropeptide receptor A26	0.052	0.1429	0.1429
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0089	0.0089
Brugia malayi	intermediate filament protein	0.0093	0.0229	0.3202
Schistosoma mansoni	phd/f-box containing protein	0.0018	0.0018	0.0018
Echinococcus granulosus	phosphoglycerate mutase	0.006	0.0136	0.0136
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0016	0.0013	0.0013
Echinococcus granulosus	lamin	0.0093	0.0229	0.0229
Loa Loa (eye worm)	intermediate filament protein	0.0093	0.0229	0.0229
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0068	0.0159	0.0159
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0105	0.0262	0.0262
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0043	0.0088	0.0088
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0042	0.0084	0.2198
Mycobacterium ulcerans	hypothetical protein	0.2108	0.5888	1
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0022	0.0029	0.0029
Brugia malayi	hypothetical protein	0.0266	0.0715	1
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0018	0.0018
Schistosoma mansoni	cpg binding protein	0.0066	0.0152	0.0152
Trypanosoma brucei	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative	0.006	0.0136	0.0118
Trypanosoma brucei	glycerolphosphate mutase, putative	0.006	0.0136	0.0118
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Mycobacterium ulcerans	phosphoglycerate mutase	0.006	0.0136	0.0091
Mycobacterium leprae	conserved hypothetical protein	0.006	0.0136	1
Echinococcus granulosus	serine:threonine protein phosphatase PGAM5	0.006	0.0136	0.0136
Echinococcus multilocularis	serine:threonine protein phosphatase PGAM5	0.006	0.0136	0.0136
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.006	0.0136	1
Schistosoma mansoni	lamin	0.0093	0.0229	0.0229
Schistosoma mansoni	intermediate filament proteins	0.0093	0.0229	0.0229
Echinococcus granulosus	ubiquitin specific protease 41	0.0043	0.0088	0.0088
Trichomonas vaginalis	inositol monophosphatase, putative	0.0042	0.0084	0.5877
Mycobacterium leprae	PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)	0.006	0.0136	1
Schistosoma mansoni	hypothetical protein	0.0936	0.2595	0.2595
Echinococcus granulosus	serine:threonine protein phosphatase PGAM5	0.006	0.0136	0.0136
Echinococcus granulosus	intermediate filament protein	0.0093	0.0229	0.0229
Entamoeba histolytica	phosphoglycerate mutase family protein. putative	0.006	0.0136	0.0091
Giardia lamblia	Hypothetical protein	0.2108	0.5888	1
Leishmania major	glycerolphosphate mutase, putative	0.006	0.0136	0.0118
Trypanosoma brucei	phosphoglycerate mutase protein, putative	0.006	0.0136	0.0118
Mycobacterium ulcerans	phosphoglyceromutase	0.006	0.0136	0.0091
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0105	0.0262	0.3663
Trypanosoma cruzi	Histidine phosphatase superfamily (branch 1), putative	0.006	0.0136	0.0118
Treponema pallidum	phosphoglyceromutase	0.006	0.0136	0.5
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.005	0.0107	0.0107
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0042	0.0084	0.0066
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0018	0.0018
Plasmodium falciparum	phosphoglycerate mutase, putative	0.006	0.0136	1
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0105	0.0262	0.0262
Schistosoma mansoni	jumonji domain containing protein	0.0068	0.0159	0.0159
Mycobacterium tuberculosis	Glucosyl-3-phosphoglycerate phosphatase GpgP	0.006	0.0136	1
Trypanosoma cruzi	glycerolphosphate mutase, putative	0.006	0.0136	0.0118
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0255
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.006	0.0136	0.0091
Schistosoma mansoni	protein phosphatase 2C	0.0018	0.0018	0.0018
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	0.0018	0.0018	0.0018
Toxoplasma gondii	phosphoglycerate mutase family protein	0.006	0.0136	0.396
Mycobacterium tuberculosis	Possible phosphoglycerate mutase Gpm2 (phosphoglyceromutase) (PGAM) (BPG-dependent PGAM)	0.006	0.0136	1
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0043	0.0088	0.0008
Schistosoma mansoni	phosphoglycerate mutase	0.006	0.0136	0.0136
Mycobacterium leprae	POSSIBLE HYDROLASE MUTT1	0.006	0.0136	1
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136
Trichomonas vaginalis	phosphoglycerate mutase, putative	0.006	0.0136	1
Leishmania major	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.3511	0.9831	0.983
Echinococcus granulosus	phd:f box containing protein	0.0018	0.0018	0.0018
Echinococcus multilocularis	phd:f box containing protein	0.0018	0.0018	0.0018
Brugia malayi	phosphoglycerate mutase family protein	0.006	0.0136	0.1908
Loa Loa (eye worm)	hypothetical protein	0.006	0.0136	0.0136
Entamoeba histolytica	phosphoglycerate mutase family protein, putative	0.006	0.0136	0.0091
Mycobacterium ulcerans	hypothetical protein	0.006	0.0136	0.0091
Mycobacterium leprae	PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)	0.006	0.0136	1
Echinococcus multilocularis	ubiquitin specific protease 41	0.0043	0.0088	0.0088
Trypanosoma cruzi	phosphoglycerate mutase, putative	0.006	0.0136	0.0118
Echinococcus multilocularis	inositol monophosphatase 1	0.0042	0.0084	0.0084
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0042	0.0084	0.5877
Onchocerca volvulus		0.3571	1	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0072	0.017	0.017
Echinococcus multilocularis	jumonji domain containing 1A	0.0018	0.0018	0.0018
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0066	0.0152	0.0152
Mycobacterium tuberculosis	PE-PGRS family protein PE_PGRS11	0.006	0.0136	1
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.002	0.0024	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0266	0.0715	0.0715
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0105	0.0262	0.0262
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0043	0.0088	0.007
Brugia malayi	UBASH3A protein homolog	0.006	0.0136	0.1908
Onchocerca volvulus		0.006	0.0136	0.0136
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0042	0.0084	0.5877
Echinococcus multilocularis	lysine specific demethylase 5A	0.0068	0.0159	0.0159
Loa Loa (eye worm)	jmjC domain-containing protein	0.0018	0.0018	0.0018
Brugia malayi	jmjC domain containing protein	0.0072	0.017	0.2372
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0043	0.0088	0.0088
Brugia malayi	phosphoglycerate mutase family protein	0.006	0.0136	0.1908
Schistosoma mansoni	phosphoglycerate mutase	0.006	0.0136	0.0136
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0139	0.0358	0.0358
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0105	0.0262	0.0262
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136
Leishmania major	hypothetical protein, conserved	0.006	0.0136	0.0118
Trypanosoma cruzi	phosphoglycerate mutase family member 5, putative	0.006	0.0136	0.0118
Mycobacterium tuberculosis	Possible hydrolase MutT1	0.006	0.0136	1
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0072	0.017	0.017
Toxoplasma gondii	phosphoglycerate mutase family protein	0.006	0.0136	0.396
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0043	0.0088	0.007
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.3571	1	1
Echinococcus multilocularis	JmjC domain containing protein 4	0.0018	0.0018	0.0018
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0229	0.0229
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0088	0.0088
Echinococcus multilocularis	phosphoglycerate mutase	0.006	0.0136	0.0136
Trypanosoma cruzi	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative	0.3571	1	1
Trypanosoma cruzi	glycerolphosphate mutase, putative	0.006	0.0136	0.0118
Trypanosoma cruzi	phosphoglycerate mutase protein, putative	0.006	0.0136	0.0118
Onchocerca volvulus	Protein UBASH3A homolog	0.006	0.0136	0.0136
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0255
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0105	0.0262	0.0262
Echinococcus multilocularis	survival motor neuron protein 1	0.0266	0.0715	0.0715
Echinococcus granulosus	lysine specific demethylase 6a	0.0018	0.0018	0.0018
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0255
Mycobacterium leprae	Possible phosphoglycerate mutase	0.006	0.0136	1
Toxoplasma gondii	phosphoglycerate mutase family protein	0.006	0.0136	0.396
Mycobacterium tuberculosis	Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase)	0.006	0.0136	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0043	0.0088	0.6237
Schistosoma mansoni	hypothetical protein	0.006	0.0136	0.0136

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2229709

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1798063