Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase | 0.0047 | 0.0081 | 0.5 |
Plasmodium falciparum | phosphoglucomutase-2 | 0.0047 | 0.0081 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) | 0.0047 | 0.0081 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0169 | 0.0152 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.2734 | 0.983 | 0.9828 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0169 | 0.0152 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1187 | 0.4216 | 0.4169 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0081 | 0.5 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0047 | 0.0081 | 0.4553 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0169 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.1594 | 0.5695 | 0.5674 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0081 | 0.0034 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0169 | 0.0106 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0047 | 0.0081 | 0.003 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0809 | 0.2845 | 0.2799 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0017 |
Mycobacterium leprae | conserved hypothetical protein | 0.0047 | 0.0081 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0047 | 0.0081 | 0.5 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Giardia lamblia | Hypothetical protein | 0.1641 | 0.5865 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.0179 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0124 | 0.0085 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0047 | 0.0081 | 0.0042 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Mycobacterium ulcerans | hypothetical protein | 0.1641 | 0.5865 | 1 |
Brugia malayi | UBASH3A protein homolog | 0.0047 | 0.0081 | 0.4553 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Giardia lamblia | Hypothetical protein | 0.1641 | 0.5865 | 0.5 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0809 | 0.2845 | 0.2817 |
Mycobacterium leprae | PROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) | 0.0047 | 0.0081 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.2734 | 0.983 | 0.9828 |
Schistosoma mansoni | 6-phosphofructokinase | 0.2781 | 1 | 1 |
Treponema pallidum | phosphoglyceromutase | 0.0047 | 0.0081 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0169 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.2734 | 0.983 | 0.9829 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0063 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0056 | 0.0008 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0169 | 1 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Echinococcus multilocularis | serine:threonine protein phosphatase PGAM5 | 0.0047 | 0.0081 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0081 | 0.0034 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.0047 | 0.0081 | 0.003 |
Onchocerca volvulus | 0.2781 | 1 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0124 | 0.0085 |
Loa Loa (eye worm) | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0034 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0164 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0081 | 0.0034 |
Mycobacterium leprae | POSSIBLE HYDROLASE MUTT1 | 0.0047 | 0.0081 | 0.5 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Schistosoma mansoni | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0017 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.2781 | 1 | 1 |
Plasmodium vivax | phosphoglucomutase-2, putative | 0.0047 | 0.0081 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0809 | 0.2845 | 0.2817 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0169 | 0.013 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0048 | 0.2673 |
Plasmodium falciparum | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0064 | 0.3583 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0047 | 0.0081 | 0.0042 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1187 | 0.4216 | 0.4169 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.1641 | 0.5865 | 1 |
Entamoeba histolytica | phosphoglycerate mutase family protein. putative | 0.0047 | 0.0081 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0081 | 0.0034 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.1641 | 0.5865 | 1 |
Plasmodium vivax | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2781 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0081 | 0.0017 |
Mycobacterium leprae | probable isochorismate synthase EntC | 0.0047 | 0.0081 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0169 | 0.013 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.0137 | 0.0073 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0081 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1187 | 0.4216 | 0.4169 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0169 | 0.0152 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Brugia malayi | phosphoglycerate mutase family protein | 0.0047 | 0.0081 | 0.4553 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0064 | 0.0025 |
Echinococcus granulosus | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Mycobacterium leprae | Probable phosphoglycerate mutase (phosphoglyceromutase) (phosphoglycerate phosphomutase) | 0.0047 | 0.0081 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0047 | 0.0081 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0064 | 0.0025 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Trichomonas vaginalis | phosphoglycerate mutase, putative | 0.0047 | 0.0081 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.2734 | 0.983 | 0.9828 |
Mycobacterium leprae | Possible phosphoglycerate mutase | 0.0047 | 0.0081 | 0.5 |
Echinococcus granulosus | serine:threonine protein phosphatase PGAM5 | 0.0047 | 0.0081 | 0.0042 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0169 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1187 | 0.4216 | 0.4169 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2734 | 0.983 | 0.9828 |
Loa Loa (eye worm) | hypothetical protein | 0.2781 | 1 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2781 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2781 | 1 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.2781 | 1 | 1 |
Echinococcus multilocularis | phosphoglycerate mutase | 0.0047 | 0.0081 | 0.0042 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.