Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3344 | 0.9775 | 0.9775 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0849 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3401 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3344 | 0.9775 | 0.9775 |
Giardia lamblia | Hypothetical protein | 0.2007 | 0.4538 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3401 | 1 | 1 |
Trypanosoma brucei | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1451 | 0.2359 | 0.2359 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1451 | 0.2359 | 0.2359 |
Giardia lamblia | Hypothetical protein | 0.2007 | 0.4538 | 1 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0849 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase 1 | 0.3344 | 0.9775 | 0.9775 |
Mycobacterium ulcerans | hypothetical protein | 0.2007 | 0.4538 | 0.5 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.1451 | 0.2359 | 0.2359 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3401 | 1 | 1 |
Trypanosoma cruzi | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3401 | 1 | 1 |
Echinococcus multilocularis | 6 phosphofructo 2 kinase:fructose 2 | 0.3401 | 1 | 1 |
Mycobacterium ulcerans | fructose-2,6-bisphosphatase GpmB | 0.2007 | 0.4538 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.195 | 0.4313 | 0.4313 |
Onchocerca volvulus | 0.3401 | 1 | 1 | |
Brugia malayi | intracellular kinase | 0.0849 | 0 | 0.5 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative | 0.3401 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0849 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3344 | 0.9775 | 0.9775 |
Trypanosoma brucei | 6-phosphofructo-2-kinase 2 | 0.3344 | 0.9775 | 0.9775 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0849 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0849 | 0 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.3401 | 1 | 1 |
Leishmania major | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-1-like protein | 0.1451 | 0.2359 | 0.2359 |
Entamoeba histolytica | phosphoglycerate mutase family protein, putative | 0.2007 | 0.4538 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.