Detailed information for compound 1798581

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.652 | Formula: C24H40N2OS
  • H donors: 1 H acceptors: 1 LogP: 9.01 Rotable bonds: 18
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC(=O)N/N=C/c1cccc(c1)SC
  • InChi: 1S/C24H40N2OS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-24(27)26-25-21-22-17-16-18-23(20-22)28-2/h16-18,20-21H,3-15,19H2,1-2H3,(H,26,27)/b25-21+
  • InChiKey: BPCBYVYCKPRUPI-NJNXFGOHSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Kinase, NEK 0.0085 0.0098 1
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase shark 0.0085 0.0098 0.0037
Leishmania major protein kinase, putative 0.0085 0.0098 0.5
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0102 0.013 1
Echinococcus multilocularis FL cytokine receptor 0.0085 0.0098 0.0037
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0085 0.0098 0.0037
Giardia lamblia Kinase, NEK 0.0085 0.0098 1
Toxoplasma gondii protein kinase domain-containing protein 0.0085 0.0098 0.5
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Entamoeba histolytica receptor protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0085 0.0098 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis AGC family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Entamoeba histolytica receptor protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0085 0.0098 0.0037
Schistosoma mansoni tyrosine protein kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/EPH protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0085 0.0098 0.0037
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0102 0.013 1
Brugia malayi SH2 domain containing protein 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0085 0.0098 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis receptor type guanylyl cyclase 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/DDR protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0085 0.0098 0.0098
Echinococcus multilocularis natriuretic peptide receptor 1 0.0085 0.0098 0.0037
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0085 0.0098 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus activated cdc42 kinase 1 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0036 0.0005 0.0005
Trypanosoma cruzi protein kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0098 0.0037
Trichomonas vaginalis protein kinase atn1, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) phosphatidylinositol 3 0.017 0.026 0.0264
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0085 0.0098 0.0037
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni ephrin receptor 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0085 0.0098 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trypanosoma cruzi protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0085 0.0098 0.0037
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0191 0.0299 0.0243
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Echinococcus multilocularis protein kinase 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0085 0.0098 0.0037
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0191 0.0299 0.0299
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis integrin linked protein kinase 0.0085 0.0098 0.0037
Echinococcus multilocularis activin receptor type 0.0085 0.0098 0.0037
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus activin receptor type 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Trypanosoma brucei protein kinase, putative 0.0085 0.0098 1
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Trypanosoma brucei Pseudokinase, putative 0.0085 0.0098 1
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase 0.0085 0.0098 0.0037
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0085 0.0098 0.0037
Plasmodium vivax protein kinase, putative 0.0085 0.0098 0.5
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Echinococcus granulosus ephrin type A receptor 4 A 0.0085 0.0098 0.0037
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0034 0.0002 0.0002
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Brugia malayi hypothetical protein 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus tyrosine protein kinase Src42A 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0191 0.0299 0.0243
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0102 0.013 1
Onchocerca volvulus 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus kinase suppressor of Ras 1 0.0085 0.0098 0.0037
Echinococcus granulosus raf serine:threonine protein kinase 0.0085 0.0098 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0102 0.013 1
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0029 0.0029
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis raf serine:threonine protein kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.5229 0.984 1
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0085 0.0098 0.0037
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0085 0.0098 0.0099
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0085 0.0098 0.0099
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase Blk 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0098 0.0037
Echinococcus multilocularis kinase suppressor of Ras 1 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0102 0.013 1
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TK family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Furin-like cysteine rich region family protein 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus fibroblast growth factor receptor 4 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase csk 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Plasmodium falciparum protein kinase, putative 0.0085 0.0098 0.5
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Plasmodium falciparum protein kinase, putative 0.0085 0.0098 0.5
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trypanosoma brucei Flagellum attachment zone protein 20 0.0085 0.0098 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase ABL1 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase HCK 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus tyrosine protein kinase pr2 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0085 0.0098 0.0037
Plasmodium vivax tyrosine kinase-like protein, putative 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0085 0.0098 0.0037
Brugia malayi ephrin receptor 1 precursor 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/CSK protein kinase 0.0085 0.0098 0.0099
Onchocerca volvulus 0.0085 0.0098 0.5
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0085 0.0098 0.5
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/FAK protein kinase 0.0085 0.0098 0.0099
Onchocerca volvulus 0.0085 0.0098 0.5
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0098 1
Trichomonas vaginalis protein tyrosine kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Leishmania major hypothetical protein, conserved 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0085 0.0098 0.0037
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0085 0.0098 0.5
Giardia lamblia Kinase 0.0085 0.0098 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0085 0.0098 0.0037
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0085 0.0098 0.0037
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni serine/threonine RGC 0.0085 0.0098 0.0098
Loa Loa (eye worm) TK/ACK protein kinase 0.0085 0.0098 0.0099
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Echinococcus multilocularis protein kinase 0.0085 0.0098 0.0037
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus tyrosine kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis epidermal growth factor receptor 0.0085 0.0098 0.0037
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.5229 0.984 1
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Echinococcus granulosus retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Brugia malayi C-terminal src kinase protein 1 0.0085 0.0098 0.0099
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0085 0.0098 0.0037
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0085 0.0098 0.0037
Onchocerca volvulus 0.0085 0.0098 0.5
Echinococcus multilocularis heat shock protein 70 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica ankyrin repeat protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase shark 0.0085 0.0098 0.0037
Plasmodium falciparum tyrosine kinase-like protein 0.0085 0.0098 0.5
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus multilocularis c src tyrosine kinase 0.0085 0.0098 0.0037
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0085 0.0098 0.7507
Echinococcus granulosus integrin linked protein kinase 0.0085 0.0098 0.0037
Brugia malayi SH2 domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine kinase 0.0085 0.0098 0.0037
Echinococcus granulosus epidermal growth factor receptor 0.0085 0.0098 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0085 0.0098 0.0037
Echinococcus granulosus receptor type guanylyl cyclase 0.0085 0.0098 0.0037
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi hypothetical protein 0.0085 0.0098 0.0099
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0085 0.0098 0.0037
Onchocerca volvulus 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0085 0.0098 0.0037
Echinococcus multilocularis protein KINase family member (kin 25) 0.0085 0.0098 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0085 0.0098 0.0099
Onchocerca volvulus 0.0085 0.0098 0.5
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0098 0.0098
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Brugia malayi Raf kinase 0.0085 0.0098 0.0099
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0066 0.0062 0.0063
Plasmodium vivax tyrosine kinase-like protein, putative 0.0085 0.0098 0.5
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0089 0.0107 0.0109
Echinococcus multilocularis tyrosine protein kinase Abl 0.0085 0.0098 0.0037
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Schistosoma mansoni protein tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0098 0.0037
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis activated cdc42 kinase 1 0.0085 0.0098 0.0037
Schistosoma mansoni ephrin receptor 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/ALK protein kinase 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Brugia malayi hypothetical protein 0.0085 0.0098 0.0099
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Loa Loa (eye worm) TK/Met protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0045 0.0023 0.1637
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/ABL protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0102 0.013 1
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Plasmodium falciparum protein kinase, putative 0.0085 0.0098 0.5
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.5229 0.984 1
Echinococcus granulosus c src tyrosine kinase 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) RGC/RGC protein kinase 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0085 0.0098 0.0037
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Brugia malayi bone morphogenetic protein type 1 receptor 0.0085 0.0098 0.0099
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0085 0.0098 0.0037
Echinococcus granulosus insulin receptor 0.0085 0.0098 0.0037
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0029 0.0029
Echinococcus multilocularis insulin receptor 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/EGFR protein kinase 0.0085 0.0098 0.0099
Toxoplasma gondii protein kinase 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase HCK 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Schistosoma mansoni hypothetical protein 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi protein-tyrosine kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Entamoeba histolytica tyrosin kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Onchocerca volvulus 0.0085 0.0098 0.5
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0085 0.0098 0.0098
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) serine/threonine protein kinase 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.5229 0.984 1
Echinococcus granulosus activated cdc42 kinase 1 0.0085 0.0098 0.0037
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0081 0.009 0.6931
Giardia lamblia Protein 21.1 0.0085 0.0098 1
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0085 0.0098 0.0098
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Echinococcus granulosus tyrosine kinase 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase Blk 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus tyrosine protein kinase Srms 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Brugia malayi Guanylyl cyclase protein 23 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Loa Loa (eye worm) TK/INSR protein kinase 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni serine/threonine protein kinase 0.0085 0.0098 0.0098
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Loa Loa (eye worm) TK/RYK protein kinase 0.0085 0.0098 0.0099
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0085 0.0098 0.0098
Loa Loa (eye worm) SRC-1 0.0085 0.0098 0.0099
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Brugia malayi SRC-1 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Echinococcus multilocularis transfer RNA-Thr 0.0085 0.0098 0.0037
Entamoeba histolytica serine/threonine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0099 0.0124 0.9555
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Onchocerca volvulus 0.0085 0.0098 0.5
Brugia malayi Receptor family ligand binding region containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/FER protein kinase 0.0085 0.0098 0.0099
Brugia malayi Tyrosine-protein kinase PR2 0.0085 0.0098 0.0099
Echinococcus granulosus natriuretic peptide receptor 1 0.0085 0.0098 0.0037
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Echinococcus granulosus protein kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.0066 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0048 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0085 0.0098 0.0037
Brugia malayi Immunoglobulin I-set domain containing protein 0.0085 0.0098 0.0099
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.007 0.007 0.5294
Schistosoma mansoni protein kinase 0.0085 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Trichomonas vaginalis STE family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica cysteine surface protein, putative 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK/ROR protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus tyrosine protein kinase Lyn 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Loa Loa (eye worm) protein kinase domain-containing protein 0.0085 0.0098 0.0099
Echinococcus multilocularis tyrosine protein kinase pr2 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0102 0.013 0.0132
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Echinococcus granulosus protein tyrosine kinase 0.0085 0.0098 0.0037
Onchocerca volvulus Tyrosine kinase homolog 0.0085 0.0098 0.5
Brugia malayi Tyrosine-protein kinase abl-1 0.0085 0.0098 0.0099
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0085 0.0098 0.5
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0098 0.0037
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Schistosoma mansoni tyrosine kinase 0.0085 0.0098 0.0098
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) hypothetical protein 0.0085 0.0098 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0098 0.7507
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0085 0.0098 0.7507
Leishmania major protein kinase, putative 0.0085 0.0098 0.5
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0085 0.0098 0.0037
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0085 0.0098 0.7507
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica protein kinase, putative 0.0085 0.0098 0.7507
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0085 0.0098 0.0037
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Brugia malayi Protein kinase domain containing protein 0.0085 0.0098 0.0099
Plasmodium falciparum tyrosine kinase-like protein 0.0085 0.0098 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0029 0.0029
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0085 0.0098 0.0099
Echinococcus multilocularis ephrin type A receptor 4 A 0.0085 0.0098 0.0037
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus granulosus tyrosine protein kinase Src64B 0.0085 0.0098 0.0037
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0085 0.0098 0.7507
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0034 0.0002 0.0002
Brugia malayi integrin-linked kinase 0.0085 0.0098 0.0099
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.007 0.007 0.5294
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica hypothetical protein, conserved 0.0085 0.0098 0.7507
Loa Loa (eye worm) TKL/MLK/LZK protein kinase 0.5229 0.984 1
Echinococcus multilocularis tyrosine kinase 0.0085 0.0098 0.0037
Loa Loa (eye worm) hypothetical protein 0.5229 0.984 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0085 0.0098 0.7507
Entamoeba histolytica ankyrin repeat protein 0.0085 0.0098 0.7507
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0085 0.0098 0.0099
Loa Loa (eye worm) TK protein kinase 0.0085 0.0098 0.0099
Entamoeba histolytica protein kinase domain containing protein 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0085 0.0098 0.0037
Echinococcus multilocularis tyrosine protein kinase csk 0.0085 0.0098 0.0037
Entamoeba histolytica tyrosine kinase, putative 0.0085 0.0098 0.7507
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis protein tyrosine kinase 0.0085 0.0098 0.0037
Entamoeba histolytica hypothetical protein 0.0081 0.009 0.6931
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0085 0.0098 0.0037
Entamoeba histolytica hypothetical protein 0.0085 0.0098 0.7507
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0085 0.0098 0.5
Trichomonas vaginalis TKL family protein kinase 0.0085 0.0098 0.7507
Echinococcus multilocularis tyrosine protein kinase Srms 0.0085 0.0098 0.0037
Toxoplasma gondii STE kinase 0.0085 0.0098 0.5

Activities

Activity type Activity value Assay description Source Reference
-logMIC (functional) = 0.61 Fungistatic activity against Candida albicans MTCC 227 after 48 hr by tube dilution method ChEMBL. No reference
-logMIC (functional) = 1.81 Bacteriostatic activity against Escherichia coli MTCC 1652 after 24 hr by tube dilution method ChEMBL. No reference
MBC (functional) = 0.061 uM/ml Bactericidal activity against Escherichia coli MTCC 1652 ChEMBL. No reference
MFC (functional) > 0.122 uM/ml Fungicidal activity against Candida albicans MTCC 227 ChEMBL. No reference
Ratio (functional) = 3 Ratio of MFC to MIC for Candida albicans MTCC 227 LITERATURE. No reference
Ratio (functional) = 3 Ratio of MBC to MIC for Escherichia coli MTCC 1652 LITERATURE. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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