Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0021 | 0.2804 | 0.2726 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.2804 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.2804 | 0.0376 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0107 | 0.000000002293 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0011 | 0.0107 | 0.0107 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0021 | 0.2804 | 0.0376 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 1 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0021 | 0.2804 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.2804 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0011 | 0.0107 | 0.0423 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.2523 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 1 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0021 | 0.2804 | 0.0376 |
Entamoeba histolytica | recQ family DNA helicase | 0.0011 | 0.0107 | 0.0381 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0021 | 0.2804 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.2523 | 0.2442 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0021 | 0.2804 | 0.0376 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.2804 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.2804 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.2804 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.2523 | 0.8958 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.2804 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.2523 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.2804 | 0.0376 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 1 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.2523 | 0.2523 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.2804 | 0.2726 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.2523 | 0.8958 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0107 | 0.0381 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0021 | 0.2804 | 1 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.2523 | 0.2523 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.2523 | 1 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.2804 | 0.0376 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0021 | 0.2804 | 0.0376 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.2804 | 0.0376 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.2523 | 0.8998 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.2523 | 0.5 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.2804 | 0.0376 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.2523 | 0.8998 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.2804 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.0021 | 0.2804 | 0.2804 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.2523 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.2804 | 0.2726 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 1 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.2804 | 1 |
Schistosoma mansoni | DNA helicase recq1 | 0.0021 | 0.2804 | 0.2804 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.2804 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.