Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Adenosine A2 receptor | Starlite/ChEMBL | References |
Rattus norvegicus | Adenosine A1 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear hormone receptor | 0.0392 | 1 | 1 |
Trichomonas vaginalis | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0392 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0392 | 1 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0392 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0392 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0392 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0392 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0392 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0392 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0392 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0392 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0392 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0392 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0392 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0392 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0392 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0392 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0392 | 1 | 1 |
Trypanosoma cruzi | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Trichomonas vaginalis | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0392 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0392 | 1 | 1 |
Trypanosoma brucei | thymidine kinase | 0.025 | 0.231 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0392 | 1 | 1 |
Leishmania major | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0392 | 1 | 1 |
Trichomonas vaginalis | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Onchocerca volvulus | 0.0392 | 1 | 0.5 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0392 | 1 | 1 |
Trypanosoma cruzi | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0392 | 1 | 1 |
Giardia lamblia | Deoxynucleoside kinase | 0.0374 | 0.9024 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0392 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0392 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0392 | 1 | 0.5 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0392 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0392 | 1 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0392 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0392 | 1 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0392 | 1 | 1 |
Entamoeba histolytica | thymidine kinase, putative | 0.025 | 0.231 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0392 | 1 | 1 |
Brugia malayi | steroid hormone receptor | 0.0392 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0392 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0392 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0392 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0392 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0392 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0392 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0392 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0392 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0392 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0392 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.