Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.03 | 0.4318 | 0.4318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | glutathione reductase | 0.013 | 0.1606 | 0.1606 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0055 | 0.041 | 0.0825 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0045 | 0.0257 | 0.5 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0029 | 0.0029 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0649 | 1 |
Onchocerca volvulus | Putative organic anion transporter | 0.0032 | 0.0046 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0045 | 0.0257 | 0.1351 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0055 | 0.041 | 0.0825 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0055 | 0.041 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0055 | 0.041 | 0.041 |
Plasmodium vivax | glutathione reductase, putative | 0.013 | 0.1606 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0055 | 0.041 | 0.0825 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0055 | 0.041 | 0.9893 |
Schistosoma mansoni | coup transcription factor | 0.0055 | 0.041 | 0.0825 |
Plasmodium falciparum | glutathione reductase | 0.013 | 0.1606 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.007 | 0.0649 | 0.1307 |
Schistosoma mansoni | thyroid hormone receptor | 0.0341 | 0.4969 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0029 | 0.0071 |
Schistosoma mansoni | hypothetical protein | 0.0287 | 0.41 | 0.8251 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0055 | 0.041 | 0.0825 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Trypanosoma brucei | trypanothione reductase | 0.013 | 0.1606 | 1 |
Onchocerca volvulus | 0.0055 | 0.041 | 0.9893 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0055 | 0.041 | 0.041 |
Plasmodium vivax | thioredoxin reductase, putative | 0.013 | 0.1606 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.041 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.051 | 0.051 |
Echinococcus multilocularis | organic anion transporting polypeptide 30B | 0.0032 | 0.0046 | 0.0092 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0033 | 0.0067 | 0.0067 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0055 | 0.041 | 0.0825 |
Echinococcus granulosus | Solute carrier organic anion transporter family | 0.0032 | 0.0046 | 0.0111 |
Schistosoma mansoni | single-minded | 0.0055 | 0.0422 | 0.0849 |
Brugia malayi | nuclear receptor NHR-88 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0029 | 0.0029 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0045 | 0.0257 | 0.0516 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.041 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.002 | 0.002 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.041 | 0.0825 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0055 | 0.041 | 0.041 |
Onchocerca volvulus | 0.0041 | 0.0193 | 0.425 | |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.041 | 0.1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0041 | 0.0192 | 0.0387 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0055 | 0.041 | 0.0825 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0045 | 0.0257 | 0.5 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.007 | 0.0649 | 0.1307 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0029 | 0.0029 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0045 | 0.0257 | 0.1351 |
Onchocerca volvulus | 0.0032 | 0.0046 | 0.043 | |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0269 | 0.3823 | 0.7693 |
Schistosoma mansoni | organic anion transporter | 0.0032 | 0.0046 | 0.0092 |
Schistosoma mansoni | nuclear hormone receptor | 0.0055 | 0.041 | 0.0825 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0029 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2609 | 0.5251 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0041 | 0.0192 | 0.0469 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0055 | 0.041 | 0.041 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0055 | 0.041 | 0.9893 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0055 | 0.041 | 0.0825 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.03 | 0.4318 | 0.4318 |
Brugia malayi | hypothetical protein | 0.0186 | 0.2496 | 0.2496 |
Schistosoma mansoni | thyroid hormone receptor | 0.0341 | 0.4969 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0055 | 0.041 | 0.1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0029 | 0.0029 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0055 | 0.041 | 0.041 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.007 | 0.0649 | 0.0649 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0029 | 0.0059 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.0248 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.0414 | 0.0833 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.2496 | 0.2496 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0055 | 0.041 | 0.041 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0045 | 0.0257 | 0.1397 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.3823 | 0.3823 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Plasmodium falciparum | thioredoxin reductase | 0.0045 | 0.0257 | 0.0061 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0055 | 0.041 | 0.1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.013 | 0.1606 | 1 |
Echinococcus granulosus | lamin | 0.0031 | 0.0029 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Onchocerca volvulus | Putative organic anion transporter | 0.0032 | 0.0046 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0297 | 0.4268 | 0.4268 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0055 | 0.041 | 0.0825 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0192 | 0.0192 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0165 | 0.2165 | 0.4357 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0171 | 0.2267 | 0.2267 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.007 | 0.0649 | 0.2911 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.0014 | 0.0014 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0045 | 0.0257 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0414 | 0.0833 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.007 | 0.0649 | 0.2911 |
Schistosoma mansoni | lamin | 0.0031 | 0.0029 | 0.0059 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0029 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.041 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0045 | 0.0257 | 0.0516 |
Brugia malayi | PAS domain containing protein | 0.0055 | 0.0422 | 0.0422 |
Echinococcus granulosus | single minded 2 | 0.0041 | 0.0193 | 0.047 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0049 | 0.0313 | 0.171 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0045 | 0.0257 | 0.1397 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0045 | 0.0257 | 0.1397 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.041 | 0.1 |
Schistosoma mansoni | lamin | 0.0031 | 0.0029 | 0.0059 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0055 | 0.041 | 0.0825 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0055 | 0.041 | 0.1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0055 | 0.041 | 0.0825 |
Onchocerca volvulus | 0.0032 | 0.0046 | 0.043 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0055 | 0.041 | 0.041 |
Schistosoma mansoni | organic anion transporter | 0.0032 | 0.0046 | 0.0092 |
Loa Loa (eye worm) | acetyltransferase | 0.0165 | 0.2165 | 0.2165 |
Brugia malayi | nuclear hormone receptor | 0.0055 | 0.041 | 0.041 |
Echinococcus multilocularis | Solute carrier organic anion transporter family | 0.0032 | 0.0046 | 0.0092 |
Loa Loa (eye worm) | thioredoxin reductase | 0.013 | 0.1606 | 0.1606 |
Onchocerca volvulus | Putative organic anion transporter | 0.0032 | 0.0046 | 0.043 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.007 | 0.0649 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0055 | 0.041 | 0.041 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0049 | 0.0313 | 0.171 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0055 | 0.041 | 0.0825 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0045 | 0.0257 | 0.0257 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0055 | 0.041 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0032 | 0.0046 | 0.0046 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0055 | 0.041 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0658 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0193 | 0.2609 | 0.5251 |
Toxoplasma gondii | thioredoxin reductase | 0.013 | 0.1606 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.0414 | 0.0414 |
Brugia malayi | steroid hormone receptor | 0.0055 | 0.041 | 0.041 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.013 | 0.1606 | 1 |
Onchocerca volvulus | 0.0032 | 0.0046 | 0.043 | |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0049 | 0.0313 | 0.0415 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.013 | 0.1606 | 0.3918 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0045 | 0.0257 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus granulosus | geminin | 0.0193 | 0.2609 | 0.6364 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0055 | 0.041 | 0.041 |
Brugia malayi | bHLH-PAS transcription factor | 0.0041 | 0.0193 | 0.0193 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0032 | 0.0046 | 0.0046 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0045 | 0.0257 | 0.0626 |
Loa Loa (eye worm) | sodium-independent organic anion transporter | 0.0032 | 0.0046 | 0.0046 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.013 | 0.1606 | 0.3232 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0045 | 0.0257 | 1 |
Brugia malayi | hypoxia-induced factor 1 | 0.0171 | 0.2267 | 0.2267 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0165 | 0.2165 | 0.4357 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0055 | 0.041 | 0.0825 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0055 | 0.041 | 0.041 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0045 | 0.0257 | 0.5 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0287 | 0.41 | 0.8251 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0165 | 0.2165 | 0.2165 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0045 | 0.0257 | 0.1351 |
Brugia malayi | hypothetical protein | 0.0269 | 0.3823 | 0.3823 |
Onchocerca volvulus | 0.0032 | 0.0046 | 0.043 | |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0045 | 0.0257 | 0.5 |
Brugia malayi | sodium-independent organic anion transporter family protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0055 | 0.041 | 0.0825 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.03 | 0.4318 | 0.4318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0055 | 0.041 | 0.041 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0055 | 0.041 | 0.1 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0029 | 0.0071 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.007 | 0.0649 | 0.1584 |
Onchocerca volvulus | 0.0032 | 0.0046 | 0.043 | |
Leishmania major | trypanothione reductase | 0.013 | 0.1606 | 1 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0041 | 0.0193 | 0.0388 |
Brugia malayi | prostaglandin transporter | 0.0032 | 0.0046 | 0.0046 |
Echinococcus granulosus | organic anion transporting polypeptide 30B | 0.0032 | 0.0046 | 0.0111 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0041 | 0.0192 | 0.0387 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0269 | 0.3823 | 0.9324 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0055 | 0.0422 | 0.0849 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.041 | 0.041 |
Onchocerca volvulus | 0.0055 | 0.0414 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0192 | 0.0387 |
Plasmodium falciparum | glutathione reductase | 0.0045 | 0.0257 | 0.0061 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.041 | 0.1 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0341 | 0.4969 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0049 | 0.0313 | 0.0762 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0033 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0055 | 0.041 | 0.041 |
Treponema pallidum | NADH oxidase | 0.0045 | 0.0257 | 0.5 |
Plasmodium falciparum | thioredoxin reductase | 0.013 | 0.1606 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0287 | 0.41 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.013 | 0.1606 | 0.1606 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0046 | 0.0046 |
Brugia malayi | Thioredoxin reductase | 0.013 | 0.1606 | 0.1606 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0326 | 0.4728 | 0.4728 |
Schistosoma mansoni | hypothetical protein | 0.0193 | 0.2609 | 0.5251 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0029 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0055 | 0.041 | 0.041 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0055 | 0.041 | 0.9893 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.0014 | 0.0014 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0055 | 0.041 | 0.1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0055 | 0.041 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.041 | 0.041 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0055 | 0.041 | 0.1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0055 | 0.041 | 0.041 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.016 | 0.2092 | 0.5102 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0049 | 0.0313 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0045 | 0.0257 | 0.1351 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0055 | 0.041 | 0.041 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0049 | 0.0313 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.