TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 354.852 | Formula: C16H19ClN2O3S
H donors: 1 H acceptors: 2 LogP: 3.88 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CCOCCOC(=O)/C(=C(/NCc1ccc(cc1)Cl)\SC)/C#N
InChi: 1S/C16H19ClN2O3S/c1-3-21-8-9-22-16(20)14(10-18)15(23-2)19-11-12-4-6-13(17)7-5-12/h4-7,19H,3,8-9,11H2,1-2H3/b15-14-
InChiKey: FICDJBNUICCGFJ-PFONDFGASA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0137	0.0292
Schistosoma mansoni	multidrug resistance protein	0.003	0.0016	0.0025
Brugia malayi	G-protein coupled receptor	0.0041	0.0137	0.0133
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0137	0.0283
Brugia malayi	ABC transporter family protein	0.003	0.0016	0.0012
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0137	0.0283
Onchocerca volvulus		0.0041	0.0137	0.0604
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0137	0.0292
Echinococcus granulosus	neuropeptide receptor	0.0041	0.0137	0.0292
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0083	0.0597	0.4217
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Brugia malayi	ABC transporter family protein	0.009	0.0675	0.0671
Giardia lamblia	Multidrug resistance-associated protein 1	0.003	0.0016	0.0085
Plasmodium falciparum	ABC transporter G family member 2	0.0157	0.1395	1
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Echinococcus granulosus	serotonin receptor	0.0041	0.0137	0.0292
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0041	0.0137	0.0283
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.0064	0.0385	0.1691
Schistosoma mansoni	hypothetical protein	0.013	0.1108	0.2354
Schistosoma mansoni	jumonji domain containing protein	0.0074	0.0498	0.1052
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0137	0.0283
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0056	0.0302	0.2077
Plasmodium falciparum	ABC transporter B family member 4, putative	0.003	0.0016	0.0083
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Plasmodium vivax	proteasome subunit beta type-5, putative	0.0083	0.0597	0.4265
Giardia lamblia	Proteasome subunit beta type 2	0.004	0.013	0.0925
Schistosoma mansoni	smdr1	0.003	0.0016	0.0025
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0041	0.0137	0.0283
Brugia malayi	jmjC domain containing protein	0.0093	0.0705	0.0701
Schistosoma mansoni	ATP-binding cassette sub-family g2 (white protein) (abcg2)	0.0157	0.1395	0.2965
Entamoeba histolytica	P-glycoprotein-5	0.009	0.0675	0.4776
Mycobacterium tuberculosis	Proteasome beta subunit PrcB; assembles with alpha subunit PrcA.	0.0083	0.0597	0.5324
Schistosoma mansoni	multidrug resistance protein	0.003	0.0016	0.0025
Onchocerca volvulus		0.0041	0.0137	0.0604
Onchocerca volvulus		0.0041	0.0137	0.0604
Brugia malayi	ABC transporter	0.003	0.0016	0.0012
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.0065	0.0396	0.2759
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0041	0.0137	0.0292
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0065	0.0396	0.1743
Toxoplasma gondii	ABC transporter, putative	0.003	0.0016	0.0083
Loa Loa (eye worm)	ABC transporter	0.003	0.0016	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Plasmodium vivax	SET domain protein, putative	0.0029	0.0012	0.0053
Trypanosoma cruzi	proteasome subunit beta type-2, putative	0.004	0.013	0.0828
Wolbachia endosymbiont of Brugia malayi	ABC-type multidrug transport system, ATPase and permease component	0.003	0.0016	0.5
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	myosin xvIII	0.0041	0.0137	0.0283
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	orexin receptor type 2	0.0041	0.0137	0.0292
Brugia malayi	ABC transporter family protein	0.003	0.0016	0.0012
Echinococcus multilocularis	multidrug resistance protein 1	0.009	0.0675	0.1429
Brugia malayi	Serotonin receptor	0.0041	0.0137	0.0133
Onchocerca volvulus		0.0041	0.0137	0.0604
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0041	0.0137	0.0283
Echinococcus granulosus	neuropeptide Y receptor	0.0041	0.0137	0.0292
Brugia malayi	G-protein coupled receptor	0.0041	0.0137	0.0133
Echinococcus multilocularis	ATP binding cassette sub family B	0.003	0.0016	0.0025
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Mycobacterium tuberculosis	Probable short-chain type dehydrogenase/reductase	0.0056	0.0302	0.2623
Mycobacterium leprae	proteasome (beta subunit) PrcB	0.0083	0.0597	1
Plasmodium vivax	ABC transporter B family member 7, putative	0.003	0.0016	0.0083
Toxoplasma gondii	ATP-binding cassette sub-family B member 5	0.003	0.0016	0.0083
Brugia malayi	jmjC domain containing protein	0.0034	0.0069	0.0065
Echinococcus multilocularis	allatostatin A receptor	0.0041	0.0137	0.0283
Brugia malayi	Dopamine receptor protein 2	0.0041	0.0137	0.0133
Echinococcus granulosus	allatostatin A receptor	0.0041	0.0137	0.0292
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	3-hydroxyacyl-CoA dehydrogenase	0.0056	0.0302	0.0636
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.0083	0.0597	0.0594
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Plasmodium vivax	ABC transporter B family member 6, putative	0.003	0.0016	0.0083
Brugia malayi	ABC transporter transmembrane region family protein	0.003	0.0016	0.0012
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.009	0.0675	0.4819
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Plasmodium falciparum	proteasome subunit beta type-2, putative	0.004	0.013	0.0905
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.004	0.013	0.0523
Onchocerca volvulus		0.0041	0.0137	0.0604
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0041	0.0137	0.0283
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	hypothetical protein	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	jmjC domain-containing protein	0.0059	0.0332	0.0328
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0041	0.0137	0.0292
Loa Loa (eye worm)	3-hydroxyacyl-CoA dehydrogenase type II	0.0052	0.0262	0.0257
Echinococcus granulosus	multidrug resistance protein 1	0.009	0.0675	0.1437
Echinococcus granulosus	neuropeptides capa receptor	0.0041	0.0137	0.0292
Schistosoma mansoni	hypothetical protein	0.0041	0.0137	0.0283
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Entamoeba histolytica	probable proteasome subunit beta type 2, putative	0.004	0.013	0.0828
Brugia malayi	multidrug Resistance Protein family member (mrp-5), putative	0.003	0.0016	0.0012
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0012	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Plasmodium vivax	ABC transporter G family member 2, putative	0.0157	0.1395	1
Plasmodium vivax	multidrug resistance protein 2, putative	0.003	0.0016	0.0083
Echinococcus granulosus	leukotriene A 4 hydrolase	0.0462	0.4695	1
Plasmodium falciparum	ABC transporter B family member 5, putative	0.003	0.0016	0.0083
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.003	0.0016	0.0012
Brugia malayi	G protein-coupled receptor F59B2.13	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Brugia malayi	larval opioid receptor	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	multidrug resistance protein	0.003	0.0016	0.0025
Echinococcus multilocularis	ATP binding cassette sub family G	0.0157	0.1395	0.2965
Brugia malayi	Pre-SET motif family protein	0.0029	0.0012	0.0007
Plasmodium falciparum	ABC transporter B family member 6, putative	0.003	0.0016	0.0083
Plasmodium falciparum	multidrug resistance protein 1	0.009	0.0675	0.4819
Onchocerca volvulus		0.0041	0.0137	0.0604
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0041	0.0137	0.0283
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Echinococcus multilocularis	jumonji domain containing protein	0.004	0.0125	0.0257
Echinococcus multilocularis	neuropeptide receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus multilocularis	leukotriene A 4 hydrolase	0.0462	0.4695	1
Leishmania major	proteasome beta 5 subunit, putative	0.0083	0.0597	0.4217
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.0083	0.0597	0.4217
Schistosoma mansoni	hypothetical protein	0.0041	0.0137	0.0283
Onchocerca volvulus		0.0041	0.0137	0.0604
Loa Loa (eye worm)	G-protein coupled receptor	0.0041	0.0137	0.0133
Wolbachia endosymbiont of Brugia malayi	ABC-type protease secretion system, ATPase and permease component, AprD	0.003	0.0016	0.5
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0029	0.0012	0.0053
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0034	0.0069	0.0138
Brugia malayi	Melatonin receptor type 1A	0.0041	0.0137	0.0133
Plasmodium falciparum	proteasome subunit beta type-5	0.0083	0.0597	0.4265
Echinococcus granulosus	lysine specific demethylase 5A	0.0034	0.0069	0.0147
Leishmania major	ATP-binding cassette protein subfamily G, member 4, putative	0.0157	0.1395	1
Schistosoma mansoni	opsin-like receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0056	0.0302	0.0636
Echinococcus multilocularis	ATP binding cassette sub family B	0.003	0.0016	0.0025
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.0065	0.0396	0.0844
Echinococcus granulosus	multidrug resistance protein 1	0.009	0.0675	0.1437
Loa Loa (eye worm)	neuropeptide F receptor	0.0041	0.0137	0.0133
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0041	0.0137	0.0292
Echinococcus granulosus	neuropeptide receptor	0.0041	0.0137	0.0292
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	g-protein coupled receptor	0.0041	0.0137	0.0283
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	neuropeptide Y receptor	0.0041	0.0137	0.0283
Plasmodium falciparum	ABC transporter B family member 3, putative	0.003	0.0016	0.0083
Plasmodium vivax	ABC transporter B family member 4, putative	0.003	0.0016	0.0083
Echinococcus granulosus	neuropeptides capa receptor	0.0041	0.0137	0.0292
Brugia malayi	hypothetical protein	0.0212	0.1995	0.1991
Loa Loa (eye worm)	neuropeptide F receptor	0.0041	0.0137	0.0133
Brugia malayi	multidrug resistance protein 3	0.009	0.0675	0.0671
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0041	0.0137	0.0292
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	adenoreceptor	0.0041	0.0137	0.0283
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Echinococcus multilocularis	sex peptide receptor	0.0041	0.0137	0.0283
Echinococcus granulosus	jumonji domain containing protein	0.004	0.0125	0.0266
Echinococcus granulosus	ATP binding cassette sub family G	0.0157	0.1395	0.2972
Trichomonas vaginalis	ABC transporter, half transporter, putative	0.009	0.0675	0.3017
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.009	0.0675	0.1437
Echinococcus multilocularis	dro:myosuppressin receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0041	0.0137	0.0283
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Echinococcus multilocularis	orexin receptor type 2	0.0041	0.0137	0.0283
Schistosoma mansoni	ABC transporter	0.0133	0.1139	0.2418
Trypanosoma cruzi	ABC transporter, putative	0.0157	0.1395	1
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0041	0.0137	0.0133
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0041	0.0137	0.0133
Mycobacterium ulcerans	proteasome PrcB	0.0083	0.0597	0.4217
Plasmodium vivax	ABC transporter B family member 3, putative	0.003	0.0016	0.0083
Schistosoma mansoni	hypothetical protein	0.0041	0.0137	0.0283
Leishmania major	proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative	0.0065	0.0396	0.2759
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Trichomonas vaginalis	set domain proteins, putative	0.0231	0.2199	1
Echinococcus granulosus	3 hydroxyacyl coenzyme A dehydrogenase type 2	0.0056	0.0302	0.0644
Echinococcus multilocularis	serotonin receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus multilocularis	neuropeptide receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.004	0.013	0.0268
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0041	0.0137	0.0283
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0041	0.0137	0.0133
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.004	0.013	0.0523
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Plasmodium falciparum	multidrug resistance-associated protein 1	0.003	0.0016	0.0083
Echinococcus granulosus	neuropeptide s receptor	0.0041	0.0137	0.0292
Brugia malayi	Serotonin receptor	0.0041	0.0137	0.0133
Entamoeba histolytica	proteasome subunit beta type 5 precursor, putative	0.0083	0.0597	0.4217
Echinococcus granulosus	ATP binding cassette sub family G	0.0157	0.1395	0.2972
Loa Loa (eye worm)	ABC transporter transmembrane region family protein	0.003	0.0016	0.0012
Trichomonas vaginalis	ABC transporter, putative	0.009	0.0675	0.3017
Schistosoma mansoni	multidrug resistance protein	0.009	0.0675	0.1429
Echinococcus granulosus	peregrin	0.0028	0.0004	0.0009
Trichomonas vaginalis	ABC transporter, half transporter, putative	0.009	0.0675	0.3017
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0137	0.0292
Loa Loa (eye worm)	ABC transporter	0.0133	0.1139	0.1135
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0041	0.0137	0.0283
Brugia malayi	multidrug resistance related protein 1	0.003	0.0016	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0041	0.0137	0.0604
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0012	0.0016
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0041	0.0137	0.0283
Giardia lamblia	Proteasome subunit beta type 1	0.0065	0.0396	0.2882
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0041	0.0137	0.0292
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0029	0.0012	0.0016
Giardia lamblia	ABC transporter, putative	0.003	0.0016	0.0085
Loa Loa (eye worm)	ATP-binding cassette sub-family B member 2	0.009	0.0675	0.0671
Onchocerca volvulus		0.0041	0.0137	0.0604
Echinococcus multilocularis	fmrfamide receptor	0.0041	0.0137	0.0283
Plasmodium vivax	proteasome subunit beta type-1, putative	0.0065	0.0396	0.2819
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.009	0.0675	0.1429
Echinococcus granulosus	PHD finger protein rhinoceros	0.0028	0.0004	0.0009
Brugia malayi	putative neuropeptide receptor	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	ATP binding cassette sub family G	0.0157	0.1395	0.2972
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0012	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	biogenic amine 5HT receptor	0.0041	0.0137	0.0292
Echinococcus multilocularis	neuropeptide s receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0041	0.0137	0.0283
Echinococcus granulosus	multidrug resistance protein 1	0.0064	0.0385	0.082
Echinococcus granulosus	somatostatin receptor	0.0041	0.0137	0.0292
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Brugia malayi	neuropeptide F receptor	0.0041	0.0137	0.0133
Brugia malayi	RE15519p	0.0041	0.0137	0.0133
Echinococcus granulosus	g-protein coupled receptor	0.0041	0.0137	0.0292
Leishmania major	ATP-binding cassette protein subfamily B, member 2, putative	0.009	0.0675	0.4776
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0224	0.022
Brugia malayi	hypothetical protein	0.003	0.0016	0.0012
Brugia malayi	ABC transporter transmembrane region family protein	0.003	0.0016	0.0012
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0041	0.0137	0.0133
Schistosoma mansoni	opsin-like receptor	0.0041	0.0137	0.0283
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0157	0.1395	1
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Brugia malayi	Proteasome A-type and B-type family protein	0.0083	0.0597	0.0594
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0137	0.0292
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0137	0.0283
Toxoplasma gondii	proteasome subunit beta type 1, putative	0.0065	0.0396	0.2819
Loa Loa (eye worm)	hypothetical protein	0.0952	1	1
Echinococcus multilocularis	multidrug resistance associated protein 1	0.003	0.0016	0.0025
Toxoplasma gondii	proteasome subunit beta type, putative	0.0083	0.0597	0.4265
Schistosoma mansoni	growth hormone secretagogue receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	proteasome subunit beta type 2	0.004	0.013	0.0126
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0034	0.0069	0.0138
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Plasmodium vivax	ABC transporter B family member 5, putative	0.003	0.0016	0.0083
Echinococcus granulosus	dro:myosuppressin receptor	0.0041	0.0137	0.0292
Trypanosoma cruzi	proteasome beta 6 subunit, putative	0.0065	0.0396	0.2759
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	amine GPCR	0.0041	0.0137	0.0283
Echinococcus granulosus	G protein coupled receptor 139	0.0041	0.0137	0.0292
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0137	0.0283
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0041	0.0137	0.0283
Brugia malayi	Dopamine receptor	0.0041	0.0137	0.0133
Trichomonas vaginalis	abcb9, putative	0.009	0.0675	0.3017
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.0083	0.0597	0.2664
Chlamydia trachomatis	ABC transporter ATP binding protein/permease	0.009	0.0675	0.5
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Schistosoma mansoni	neuropeptide F-like receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0041	0.0137	0.0283
Entamoeba histolytica	ABC transporter, putative	0.0157	0.1395	1
Echinococcus multilocularis	multidrug resistance protein 1	0.0064	0.0385	0.0812
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Entamoeba histolytica	P-glycoprotein-2, putative	0.009	0.0675	0.4776
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0041	0.0137	0.0133
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.009	0.0675	0.3017
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	melatonin receptor type 1A	0.0041	0.0137	0.0133
Leishmania major	3-oxoacyl-(acyl-carrier protein) reductase, putative	0.0056	0.0302	0.2077
Plasmodium vivax	multidrug resistance protein 1, putative	0.009	0.0675	0.4819
Loa Loa (eye worm)	leukotriene A4 hydrolase	0.0462	0.4695	0.4693
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Echinococcus multilocularis	lysine specific demethylase 5A	0.0034	0.0069	0.0138
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0041	0.0137	0.0283
Giardia lamblia	MRP-like ABC transporter	0.003	0.0016	0.0085
Trichomonas vaginalis	abcb9, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	proteasome (prosome, macropain)	0.0083	0.0597	0.1265
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0041	0.0137	0.0133
Echinococcus multilocularis	ATP binding cassette sub family G	0.0157	0.1395	0.2965
Loa Loa (eye worm)	hypothetical protein	0.009	0.0675	0.0671
Echinococcus multilocularis	proteasome (prosome, macropain) subunit, beta	0.0065	0.0396	0.0836
Echinococcus granulosus	multidrug resistance associated protein 7	0.003	0.0016	0.0034
Loa Loa (eye worm)	ABC transporter	0.003	0.0016	0.0012
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0157	0.1395	1
Schistosoma mansoni	amine GPCR	0.0041	0.0137	0.0283
Onchocerca volvulus		0.0041	0.0137	0.0604
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Trypanosoma brucei	proteasome subunit beta type-5, putative	0.0083	0.0597	0.4217
Echinococcus granulosus	neuropeptide receptor A26	0.0041	0.0137	0.0292
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0644	0.064
Echinococcus granulosus	biogenic amine 5HT receptor	0.0041	0.0137	0.0292
Echinococcus granulosus	5'partial\|ATP binding cassette sub family B	0.0088	0.0644	0.1372
Echinococcus multilocularis	ATP binding cassette sub family B	0.003	0.0016	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Brugia malayi	follicle stimulating hormone receptor	0.0041	0.0137	0.0133
Echinococcus multilocularis	multidrug resistance protein 1	0.009	0.0675	0.1429
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Echinococcus granulosus	ATP binding cassette sub family B	0.003	0.0016	0.0034
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Mycobacterium ulcerans	short-chain type dehydrogenase/reductase	0.0056	0.0302	0.2077
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.004	0.013	0.0268
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Giardia lamblia	ABC transporter	0.0154	0.1365	1
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.009	0.0675	0.3017
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	G-protein coupled receptor	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	ATP binding cassette sub family B	0.003	0.0016	0.0034
Schistosoma mansoni	leukotriene A4 hydrolase (M01 family)	0.0462	0.4695	1
Plasmodium falciparum	multidrug resistance-associated protein 2	0.003	0.0016	0.0083
Trichomonas vaginalis	multidrug resistance protein 1, 2, putative	0.009	0.0675	0.3017
Onchocerca volvulus		0.0041	0.0137	0.0604
Trichomonas vaginalis	abcb9, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	ATP binding cassette sub family B	0.0088	0.0644	0.1365
Mycobacterium ulcerans	transmembrane ABC transporter ATP-binding protein	0.0157	0.1395	1
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Brugia malayi	Pre-SET motif family protein	0.0203	0.1895	0.1892
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Schistosoma mansoni	amine GPCR	0.0041	0.0137	0.0283
Giardia lamblia	Multidrug resistance-associated protein 1	0.003	0.0016	0.0085
Giardia lamblia	Proteasome subunit beta type 5 precursor	0.0083	0.0597	0.436
Loa Loa (eye worm)	hypothetical protein	0.003	0.0016	0.0012
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0041	0.0137	0.0283
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Leishmania major	p-glycoprotein	0.009	0.0675	0.4776
Schistosoma mansoni	proteasome subunit beta 2 (T01 family)	0.004	0.013	0.0268
Trichomonas vaginalis	ABC transporter, putative	0.009	0.0675	0.3017
Schistosoma mansoni	proteasome subunit beta 1 (T01 family)	0.0065	0.0396	0.0836
Plasmodium falciparum	proteasome subunit beta type-1, putative	0.0065	0.0396	0.2819
Brugia malayi	sulfakinin receptor protein	0.0041	0.0137	0.0133
Echinococcus granulosus	multidrug resistance protein 1	0.0064	0.0385	0.082
Echinococcus granulosus	neuropeptide FF receptor 2	0.0041	0.0137	0.0292
Leishmania major	ATP-binding cassette protein subfamily G, member 6, putative	0.0157	0.1395	1
Schistosoma mansoni	amine GPCR	0.0041	0.0137	0.0283
Leishmania major	proteasome beta 2 subunit, putative	0.004	0.013	0.0828
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Echinococcus granulosus	proteasome prosome macropain	0.0083	0.0597	0.1273
Echinococcus granulosus	tm gpcr rhodopsin	0.0041	0.0137	0.0292
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.009	0.0675	0.1437
Plasmodium vivax	proteasome subunit beta type-2, putative	0.004	0.013	0.0905
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0203	0.1895	0.1892
Trypanosoma cruzi	ATP-binding cassette protein, putative	0.0157	0.1395	1
Echinococcus granulosus	7TM GPCR rhodopsin	0.0041	0.0137	0.0292
Trichomonas vaginalis	lipid A export ATP-binding/permease protein msba, putative	0.009	0.0675	0.3017
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.009	0.0675	0.1437
Schistosoma mansoni	ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7)	0.003	0.0016	0.0025
Brugia malayi	AKH receptor	0.0041	0.0137	0.0133
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.009	0.0675	0.3017
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.009	0.0675	0.1429
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0029	0.0012	0.0016
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Trypanosoma brucei	proteasome beta 6 subunit	0.0065	0.0396	0.2759
Onchocerca volvulus		0.0041	0.0137	0.0604
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Onchocerca volvulus		0.0041	0.0137	0.0604
Loa Loa (eye worm)	hypothetical protein	0.009	0.0675	0.0671
Schistosoma mansoni	smdr2	0.009	0.0675	0.1429
Echinococcus multilocularis	ATP binding cassette sub family G	0.0157	0.1395	0.2965
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.009	0.0675	0.1437
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0041	0.0137	0.0292
Echinococcus granulosus	sex peptide receptor	0.0041	0.0137	0.0292
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	neuropeptide F-like receptor	0.0041	0.0137	0.0283
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.009	0.0675	0.3017
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Brugia malayi	ABC transporter family protein	0.003	0.0016	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Trichomonas vaginalis	ABC transporter, putative	0.009	0.0675	0.3017
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0041	0.0137	0.0604
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Entamoeba histolytica	P-glycoprotein-1	0.009	0.0675	0.4776
Brugia malayi	G protein-coupled receptor	0.0041	0.0137	0.0133
Onchocerca volvulus		0.0029	0.0012	0.0034
Brugia malayi	ORL1-like opioid receptor	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0041	0.0137	0.0283
Brugia malayi	3-hydroxyacyl-CoA dehydrogenase type II	0.0056	0.0302	0.0298
Schistosoma mansoni	neuropeptide receptor	0.0041	0.0137	0.0283
Echinococcus granulosus	multidrug resistance associated protein 1	0.003	0.0016	0.0034
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Trypanosoma brucei	ABC transporter, putative	0.0157	0.1395	1
Brugia malayi	ABC transporter family protein	0.0133	0.1139	0.1135
Entamoeba histolytica	P-glycoprotein-2	0.009	0.0675	0.4776
Entamoeba histolytica	P-glycoprotein-2	0.009	0.0675	0.4776
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0041	0.0137	0.0292
Mycobacterium tuberculosis	Probable transmembrane multidrug efflux pump	0.009	0.0675	0.6029
Onchocerca volvulus		0.0231	0.2199	1
Brugia malayi	putative neuropeptide receptor NPR1	0.0041	0.0137	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0041	0.0137	0.0292
Schistosoma mansoni	multidrug resistance protein	0.003	0.0016	0.0025
Schistosoma mansoni	multidrug resistance protein	0.009	0.0675	0.1429
Schistosoma mansoni	amine GPCR	0.0041	0.0137	0.0283
Loa Loa (eye worm)	multidrug resistance protein 3	0.009	0.0675	0.0671
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0041	0.0137	0.0133
Plasmodium falciparum	ABC transporter B family member 7, putative	0.003	0.0016	0.0083
Echinococcus multilocularis	serotonin receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.009	0.0675	0.1429
Brugia malayi	proteasome subunit beta type 1	0.0065	0.0396	0.0392
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0093	0.0705	0.1502
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Onchocerca volvulus		0.0041	0.0137	0.0604
Onchocerca volvulus		0.0041	0.0137	0.0604
Plasmodium vivax	multidrug resistance-associated protein 1, putative	0.003	0.0016	0.0083
Schistosoma mansoni	opsin-like receptor	0.0041	0.0137	0.0283
Onchocerca volvulus		0.0041	0.0137	0.0604
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.009	0.0675	0.1429
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0041	0.0137	0.0133
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	proteasome subunit beta type 1	0.0065	0.0396	0.0392
Echinococcus granulosus	multidrug resistance protein 1	0.009	0.0675	0.1437
Mycobacterium tuberculosis	Probable conserved transmembrane ATP-binding protein ABC transporter	0.013	0.1108	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0041	0.0137	0.0292
Echinococcus multilocularis	G protein coupled receptor 139	0.0041	0.0137	0.0283
Echinococcus granulosus	hypothetical protein	0.0041	0.0137	0.0292
Echinococcus granulosus	7tm_1 domain containing protein	0.0041	0.0137	0.0292
Onchocerca volvulus		0.0041	0.0137	0.0604
Echinococcus granulosus	rhodopsin orphan GPCR	0.0041	0.0137	0.0292
Echinococcus multilocularis	neuropeptides capa receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0041	0.0137	0.0283
Schistosoma mansoni	histamine h1 receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	proteasome catalytic subunit 3 (T01 family)	0.0083	0.0597	0.1265
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0041	0.0137	0.0133
Trichomonas vaginalis	ABC transporter, putative	0.009	0.0675	0.3017
Brugia malayi	P-glycoprotein-like protein	0.003	0.0016	0.0012
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0029	0.0012	0.0016
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Loa Loa (eye worm)	jmjC domain-containing protein	0.0034	0.0069	0.0065
Entamoeba histolytica	P-glycoprotein 5, putative	0.009	0.0675	0.4776
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Echinococcus multilocularis	neuropeptide receptor A26	0.0041	0.0137	0.0283
Brugia malayi	neuropeptide F receptor	0.0041	0.0137	0.0133
Plasmodium falciparum	multidrug resistance protein 2	0.003	0.0016	0.0083
Toxoplasma gondii	ATP-binding cassette G family transporter ABCG84	0.0157	0.1395	1
Onchocerca volvulus		0.009	0.0675	0.3054
Schistosoma mansoni	biogenic amine receptor	0.0041	0.0137	0.0283
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.009	0.0675	0.1429
Echinococcus granulosus	proteasome prosome macropain subunit beta	0.004	0.013	0.0277
Toxoplasma gondii	ABC transporter family protein	0.003	0.0016	0.0083
Schistosoma mansoni	multidrug resistance protein	0.009	0.0675	0.1429
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0041	0.0137	0.0283
Trypanosoma cruzi	20S proteasome subunit	0.004	0.013	0.0828
Echinococcus multilocularis	g protein coupled receptor	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.003	0.0016	0.0012
Loa Loa (eye worm)	TYRA-2 protein	0.0041	0.0137	0.0133
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0029	0.0012	0.0016
Toxoplasma gondii	ABC transporter transmembrane region domain-containing protein	0.003	0.0016	0.0083
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	ATP binding cassette sub family B	0.003	0.0016	0.0025
Trichomonas vaginalis	ATP-binding cassette transporter, putative	0.009	0.0675	0.3017
Toxoplasma gondii	proteasome subunit beta type 2, putative	0.004	0.013	0.0905
Echinococcus granulosus	g protein coupled receptor	0.0041	0.0137	0.0292
Trypanosoma brucei	proteasome subunit beta type-2, putative	0.004	0.013	0.0828
Echinococcus granulosus	fmrfamide receptor	0.0041	0.0137	0.0292
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0041	0.0137	0.0283
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Toxoplasma gondii	ATP-binding cassette transporter ABC.B1	0.009	0.0675	0.4819
Trypanosoma brucei	ATP-binding cassette protein, putative	0.0157	0.1395	1
Schistosoma mansoni	neuropeptide f receptor 76f	0.0041	0.0137	0.0283
Trichomonas vaginalis	taga, putative	0.009	0.0675	0.3017
Schistosoma mansoni	multidrug resistance protein	0.003	0.0016	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0093	0.0705	0.1494
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0041	0.0137	0.0133
Plasmodium vivax	multidrug resistance-associated protein 2, putative	0.003	0.0016	0.0083
Loa Loa (eye worm)	ABC transporter	0.003	0.0016	0.0012
Brugia malayi	GnHR receptor homolog	0.0041	0.0137	0.0133
Echinococcus granulosus	neuropeptide Y receptor	0.0041	0.0137	0.0292
Brugia malayi	proteasome subunit beta type 2	0.004	0.013	0.0126
Brugia malayi	hypothetical protein	0.0041	0.0137	0.0133
Echinococcus multilocularis	neuropeptides capa receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis		0.003	0.0016	0.0025
Echinococcus granulosus	histone lysine methyltransferase setb	0.0029	0.0012	0.0025
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	multidrug resistance associated protein 7	0.003	0.0016	0.0025
Onchocerca volvulus		0.0041	0.0137	0.0604
Echinococcus multilocularis	somatostatin receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	neuropeptide Y receptor	0.0041	0.0137	0.0283
Entamoeba histolytica	P-glyco protein 6, putative	0.009	0.0675	0.4776
Echinococcus multilocularis	fmrfamide receptor	0.0041	0.0137	0.0283
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0041	0.0137	0.0283
Entamoeba histolytica	proteasome subunit beta type 1, putative	0.0065	0.0396	0.2759

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2272998

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1803604